51 supplements analyzed and ranked by clinical evidence.
Sleep improved; pain eased
Sleep worsened; sedation rose
Sleep onset/quality
31%↓ delirium
Sleep quality +64%
PSQI -3.1
Deep sleep +2.5pp
Vagal HRV + sleep
PSQI ↓ ~4
Stress hormones + sleep
Sleep quality + latency
Deep sleep + duration
Anxiety/stress eased
TRP↓ melatonin↓
Sleep onset↓ duration↑
Sleep quality↑
Pain/spasticity, sleep +
Sleep efficiency +6.85
Sleep efficiency/time +58m
Fewer wakings/arousals
PSQI -1.7
Better sleep quality
+58 min sleep
Fewer sleep problems
Sleep quality +1.7 PSQI
Sleep timing variability
Sleep duration +
Sleep quality ↑
+84 min sleep
+6.6% efficiency
PLM ↓, sleep ↑
Melatonin phase shift
Insomnia/cortisol ↓
SWS/EEG ↑
Deeper sleep +N3
Faster night consolidation
Duration↓wakings↑58min
Efficiency↑latency↓1.7pp
PSQI↑cortisol↓
Sleep quality, TST
Latency, efficiency
+25 min TIB
Improved sleep efficiency
Sleep continuity +TST
Sleep quality modestly
Sleep improved, -1.7
Sleep quality + duration
Deep sleep +50%
Sleep onset −24 min
Sleep quality improved
Sleep latency ↓16 min
Overall sleep quality improved
Insomnia severity, PSQI ↓
Sleep onset/quality +21.7 min
Deeper sleep, no next-day impairment
Morning slowing, then better sleep
Sleep onset/quality: improved
Cortisol/stress: reduced
Sleep latency: -7.7 min
Sleep quality: +PSQI, −2.9 ISI
Deep sleep ↑, REM ↓
Melatonin/NAC: better sleep
Oxidative stress: +GSH, -MDA
Sleep quality, +PSQI
Sleep duration, improved
Sleepiness, reduced
Subjective sleep quality +
Sleep duration/latency +23 min
Less waking, better sleep
PSQI −44%, better sleep
Improved sleep with lithium
Sleep improved
Deep sleep +
Sleep maintenance, onset
Daytime sleepiness/functioning
Sleep quality: no data
Pain/swelling: worse sleep
Relapse -20%: better sleep
Sleep quality: +
Sleep restoration: +
Pain ↓ sleep +
PSQI p<0.0001
PSQI ↓, ALT/viremia ↓
PSQI ↑ slight
TST +27 min
Fewer night sweats
+73% hot flush drop
Better sleep efficiency
Improved sleep; +73% hot flushes
Sleep improved; MN 5.7→1.4
Insomnia improved more
Mood/anxiety better
Better sleep +98 days
Less cold sleep issues
Sleep routine improved
No sleep change
Faster sleep onset; +24 min
Longer, better sleep; +22 min
Less fatigue, better sleep
MMSE +3.4
Better oxygenation, sleep stages
Less insomnia, +SaO2
Melatonin + sleep quality
Sleep quality, duration
Vasomotor symptoms −38%
Physical/social symptoms −24%
Better sleep quality, -1.5
Longer sleep, better efficiency
NHP sleep p<0.001
Sleep + mood; ratio↓
Sleep +15 min
Sleep modestly improved
Hot flushes/night sweats −73%
Insomnia, total score↓
Anxiety↓, sleep better
Longer sleep +27 min
Lower anxiety −5%
Less fatigue/stress
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