Passion Flower
7 benefits mapped to clinical evidence across supplements.
Dose per serving from products
221 products in our catalogue print how much Passion Flower a serving holds.
Most common: 100 mg to 250 mg, 31% of 221 products.
| Dose per serving | Products |
|---|---|
| 2.5 mg or less | 2 |
| 2.5 mg to 5 mg | 11 |
| 5 mg to 10 mg | 6 |
| 10 mg to 25 mg | 19 |
| 25 mg to 50 mg | 44 |
| 50 mg to 100 mg | 39 |
| 100 mg to 250 mg | 68 |
| 250 mg to 500 mg | 23 |
| over 500 mg | 9 |
Dose per serving from research
5 study groups in 5 studies say how much Passion Flower participants took a day.
These are the doses the studies gave. They are not a recommendation.
Most common: 250 mg to 500 mg, 40% of 5 study groups.
| Daily dose | Study groups |
|---|---|
| 10 mg or less | 1 |
| 10 mg to 25 mg | 0 |
| 25 mg to 50 mg | 1 |
| 50 mg to 100 mg | 1 |
| 100 mg to 250 mg | 0 |
| 250 mg to 500 mg | 2 |
Benefit Evidence
Anxiety ↓; focus unchanged
No cognitive/sedation effect
EEG shift; focus stable
Anxiety ↓; focus unchanged
No cognitive/sedation effect
EEG shift; focus stable
Research sources
Stress & Anxiety (10)
- Preoperative oral Passiflora incarnata reduces anxiety in ambulatory surgery patients: a double-blind, placebo-controlled study
PubMed ID: 18499602
Premedication trial showed significant reduction in preoperative anxiety without sedation — robust anxiolysis evidence.
- Effects of Passiflora incarnata and Valeriana officinalis in the control of anxiety due to tooth extraction: a randomized controlled clinical trial
PubMed ID: 38743126
Passiflora lowered STAI‑S during tooth extraction vs placebo — moderate evidence for reduced anxiety.
- Effects of Passiflora incarnata Linnaeus on polysomnographic sleep parameters in subjects with insomnia disorder: a double-blind randomized placebo-controlled study
PubMed ID: 31714321
Increased total sleep time in insomnia patients may reflect reduced nighttime restlessness.
- Herbal medicines as anxiolytics prior to third molar surgical extraction. A randomized controlled clinical trial
PubMed ID: 32951121
Large RCT: 500 mg Passiflora produced anxiolysis comparable to midazolam for dental procedure — strong evidence for anxiety reduction.
- Effects of passiflora incarnata and midazolam for control of anxiety in patients undergoing dental extraction
PubMed ID: 27918731
Passiflora before third‑molar extraction reduced anxiety similarly to midazolam with fewer adverse effects — strong anxiolytic signal.
- Passiflora incarnata Linneaus as an anxiolytic before spinal anesthesia
PubMed ID: 22048283
Single dose Passiflora prevented preoperative anxiety rise — practical support during acute nervousness.
- Effects of a fixed herbal drug combination (Ze 185) to an experimental acute stress setting in healthy men - An explorative randomized placebo-controlled double-blind study
PubMed ID: 29433687
Herbal combination including Passiflora reduced subjective anxiety under acute stress — supportive but multicomponent.
- A combination of plant extracts in the treatment of outpatients with adjustment disorder with anxious mood: controlled study versus placebo
PubMed ID: 9107558
Multi‑herb product including passionflower reduced HAM‑A vs placebo — anxiety reduction plausible though attribution uncertain.
- Passionflower in the treatment of generalized anxiety: a pilot double-blind randomized controlled trial with oxazepam
PubMed ID: 11679026
Pilot RCT: Passiflora reduced generalized anxiety comparably to oxazepam — supports an anxiolytic effect.
- Passionflower in the treatment of opiates withdrawal: a double-blind randomized controlled trial
PubMed ID: 11679027
Adjunctive Passiflora improved mental/emotional opiate‑withdrawal symptoms — anxiolytic/mental symptom benefit.
Mood balance (10)
- Effects of a fixed herbal drug combination (Ze 185) to an experimental acute stress setting in healthy men - An explorative randomized placebo-controlled double-blind study
PubMed ID: 29433687
Herbal combo including passionflower reduced subjective anxiety during acute stress — suggests calming effect but multicomponent.
- A combination of plant extracts in the treatment of outpatients with adjustment disorder with anxious mood: controlled study versus placebo
PubMed ID: 9107558
Multi‑extract herbal product including passionflower lowered HAM‑A scores vs placebo — supports calmer mood though not isolated.
- Passionflower in the treatment of generalized anxiety: a pilot double-blind randomized controlled trial with oxazepam
PubMed ID: 11679026
Small RCT: Passiflora reduced generalized anxiety similarly to oxazepam — consistent with calmer mood.
- Passionflower in the treatment of opiates withdrawal: a double-blind randomized controlled trial
PubMed ID: 11679027
Adjunctive improvement in mental withdrawal symptoms indicates emotional symptom support.
- Preoperative oral Passiflora incarnata reduces anxiety in ambulatory surgery patients: a double-blind, placebo-controlled study
PubMed ID: 18499602
Oral Passiflora before outpatient surgery reduced anxiety without sedation — calming effect with preserved alertness.
- Passiflora incarnata Linneaus as an anxiolytic before spinal anesthesia
PubMed ID: 22048283
Single preoperative dose prevented expected anxiety rise without cognitive/hemodynamic impairment — indicates calmer mood.
- The impact of combined nutraceutical supplementation on quality of life and metabolic changes during the menopausal transition: a pilot randomized trial
PubMed ID: 28852842
Multi‑component product including passionflower reduced irritability in menopausal women (Kuppermann Index) — plausible contribution from passionflower but confounded.
- Effects of passiflora incarnata and midazolam for control of anxiety in patients undergoing dental extraction
PubMed ID: 27918731
Preoperative anxiolysis comparable to midazolam but with less memory loss and sedation — calmer mood with fewer side effects.
- Herbal medicines as anxiolytics prior to third molar surgical extraction. A randomized controlled clinical trial
PubMed ID: 32951121
Large triple‑blind RCT: single oral Passiflora before dental extraction reduced anxiety comparable to midazolam — supports calmer mood without heavy sedation.
- Effects of Passiflora incarnata and Valeriana officinalis in the control of anxiety due to tooth extraction: a randomized controlled clinical trial
PubMed ID: 38743126
Randomized trial: Passiflora lowered measured state anxiety during tooth extraction vs placebo — calmer mood evidence.
Focus & concentration (4)
- Herbal medicines as anxiolytics prior to third molar surgical extraction. A randomized controlled clinical trial
PubMed ID: 32951121
Anxiolysis comparable to midazolam but without adverse cognitive effects suggests preserved or enhanced calm focus.
- Passiflora incarnata Linneaus as an anxiolytic before spinal anesthesia
PubMed ID: 22048283
Preoperative prevention of anxiety increase occurred without psychomotor slowing — supports calm focus during stressful tasks.
- Preoperative oral Passiflora incarnata reduces anxiety in ambulatory surgery patients: a double-blind, placebo-controlled study
PubMed ID: 18499602
Reduced anxiety before surgery without psychomotor impairment implies preserved focus with greater calm.
- Passionflower in the treatment of generalized anxiety: a pilot double-blind randomized controlled trial with oxazepam
PubMed ID: 11679026
Anxiolysis without work‑impairing side effects vs oxazepam suggests better calm focus in daily functioning.
Sleep quality (3)
- Effects of Passiflora incarnata Linnaeus on polysomnographic sleep parameters in subjects with insomnia disorder: a double-blind randomized placebo-controlled study
PubMed ID: 31714321
Randomized, double‑blind PSG study: 2 weeks Passiflora increased total sleep time ≈23 minutes vs placebo — strong direct evidence for sleep quantity benefit.
- A double-blind, placebo-controlled investigation of the effects of Passiflora incarnata (passionflower) herbal tea on subjective sleep quality
PubMed ID: 21294203
Double‑blind crossover trial: drinking Passiflora tea for one week improved self‑rated sleep quality (subjective benefit).
- Efficacy and safety of a polyherbal sedative-hypnotic formulation NSF-3 in primary insomnia in comparison to zolpidem: a randomized controlled trial
PubMed ID: 23543804
Polyherbal product including passionflower performed similarly to zolpidem for short‑term insomnia — supports symptomatic relief though multicomponent.
Relaxation (2)
- Effects of passiflora incarnata and midazolam for control of anxiety in patients undergoing dental extraction
PubMed ID: 27918731
Clinical anxiolysis with less sedation than midazolam suggests relaxed state without heavy impairment.
- Effects of Passiflora incarnata Linnaeus on polysomnographic sleep parameters in subjects with insomnia disorder: a double-blind randomized placebo-controlled study
PubMed ID: 31714321
Increased total sleep time and within‑group sleep efficiency improvements imply deeper/restorative sleep for some users.
Sleep onset (2)
- Efficacy and safety of a polyherbal sedative-hypnotic formulation NSF-3 in primary insomnia in comparison to zolpidem: a randomized controlled trial
PubMed ID: 23543804
Polyherbal tablet (valerian, passionflower, hops) decreased sleep latency within groups — suggests easier sleep onset though multi‑ingredient.
- A double-blind, placebo-controlled investigation of the effects of Passiflora incarnata (passionflower) herbal tea on subjective sleep quality
PubMed ID: 21294203
Subjective sleep quality improvement over 1 week may include easier sleep onset (self‑reported).
Antioxidant (1)
- The Effect of Piceatannol from Passion Fruit (Passiflora edulis) Seeds on Metabolic Health in Humans
PubMed ID: 29057795
Piceatannol (passion‑fruit seed compound) improved metabolic/vascular markers—consistent with antioxidant/phytoalexin activity (fruit seed, not flower).
Similar by evidence
Supplements the same benefits carry qualifying findings for — a fact about the evidence graph, not a recommendation to swap.
Products with Passion Flower
Search all706 products whose verified label declares Passion Flower — not every bottle that mentions it in a title.
Being studied right now
Recruiting clinical trials registered on ClinicalTrials.gov. A trial in progress has no result yet — this is what the field is asking, not what it found.