Rhodiola Rosea
15 benefits mapped to clinical evidence across supplements.
Dose per serving from products
188 products in our catalogue print how much Rhodiola Rosea a serving holds.
Most common: 50 mg to 100 mg, 41% of 188 products.
| Dose per serving | Products |
|---|---|
| 10 mg or less | 2 |
| 10 mg to 25 mg | 18 |
| 25 mg to 50 mg | 25 |
| 50 mg to 100 mg | 77 |
| 100 mg to 250 mg | 32 |
| 250 mg to 500 mg | 25 |
| over 500 mg | 9 |
Dose per serving from research
19 study groups in 14 studies say how much Rhodiola Rosea participants took a day.
These are the doses the studies gave. They are not a recommendation.
Most common: 100 mg to 250 mg and 500 mg to 1 g and 1 g to 2.5 g, 26% of 19 study groups each.
| Daily dose | Study groups |
|---|---|
| 100 mg to 250 mg | 5 |
| 250 mg to 500 mg | 3 |
| 500 mg to 1 g | 5 |
| 1 g to 2.5 g | 5 |
| 2.5 g to 5 g | 1 |
Benefit Evidence
Fatigue down, attention up
~15% antifatigue
Attention/memory improved
Research sources
Mood balance (7)
- The Effects of Rhodiola rosea L. Extract on Anxiety, Stress, Cognition and Other Mood Symptoms
PubMed ID: 26502953
Open trial in mildly anxious adults reported reduced anxiety/stress and improved overall mood after 14 days.
- Effect of a Combination of Magnesium, B Vitamins, Rhodiola, and Green Tea (L-Theanine) on Chronically Stressed Healthy Individuals-A Randomized, Placebo-Controlled Study
PubMed ID: 35565828
28-day Mg+B-vit+green tea+rhodiola reduced DASS-42 stress scores clinically vs placebo; mood-related benefit for the combination.
- Clinical trial of Rhodiola rosea L. extract SHR-5 in the treatment of mild to moderate depression
PubMed ID: 17990195
Phase III randomized, doubleâblind trial showed significant reductions in depressive symptoms and related subscales vs placebo.
- A randomised, double-blind, placebo-controlled, parallel-group study of the standardised extract shr-5 of the roots of Rhodiola rosea in the treatment of subjects with stress-related fatigue
PubMed ID: 19016404
Reduced burnout and somatic complaints could improve mood; primary focus was fatigue/attention but moodârelevant changes observed.
- [Three preparations of compound Chinese herbal medicines for de-adaptation to high altitude: a randomized, placebo-controlled trial]
PubMed ID: 21486552
Improvement in symptoms including attention/memory and drowsiness could contribute to improved mood in soldiers after highâaltitude duty.
- [Effects of rhodiola rosea on oxidative stress and negative emotional states in patients with obstructive sleep apnea]
PubMed ID: 31623042
3-month use in OSA associated with reduced anxiety/depression scores (SDS/SAS) though multi-arm design confounds attribution.
- Antidepressants effects of Rhodiola capsule combined with sertraline for major depressive disorder: A randomized double-blind placebo-controlled clinical trial
PubMed ID: 32090788
Adding Rhodiola to sertraline improved depression ratings more than sertraline+placebo; dose-response noted (adjunctive benefit).
Stress & Anxiety (7)
- A randomised, double-blind, placebo-controlled, parallel-group study of the standardised extract shr-5 of the roots of Rhodiola rosea in the treatment of subjects with stress-related fatigue
PubMed ID: 19016404
Lowered cortisol awakening response and reduced burnout indicate a measurable stressâreduction effect in stressed patients.
- The Effects of Rhodiola rosea L. Extract on Anxiety, Stress, Cognition and Other Mood Symptoms
PubMed ID: 26502953
Open study in mildly anxious adults showed statistically significant reductions in anxiety after 14 days.
- Neuropeptide Y stimulation as primary target for preventive measures of maladaptative cardiovascular reactions in occupational chronic stress exposure
PubMed ID: 23272529
Multiâadaptogen supplementation improved cardiovascular responses to a mild stressor in military personnel (multiâherb mix).
- A combination of green tea, rhodiola, magnesium and B vitamins modulates brain activity and protects against the effects of induced social stress in healthy volunteers
PubMed ID: 33896388
Combined supplement containing Rhodiola modulated EEG and some stress responses during the Trier Social Stress Test.
- Effect of a Combination of Magnesium, B Vitamins, Rhodiola, and Green Tea (L-Theanine) on Chronically Stressed Healthy Individuals-A Randomized, Placebo-Controlled Study
PubMed ID: 35565828
Large RCT of a formula including Rhodiola showed clinically meaningful reduction in DASS-42 stress vs placebo (robust result for combination).
- A randomized trial of two different doses of a SHR-5 Rhodiola rosea extract versus placebo and control of capacity for mental work
PubMed ID: 12725561
Antifatigue/mental work capacity improvements under stress in cadets imply an adaptogenic, stressâbuffering effect.
- Clinical trial of Rhodiola rosea L. extract SHR-5 in the treatment of mild to moderate depression
PubMed ID: 17990195
Clinical trial in mildâmoderate depression reduced emotional instability and somatization; likely overlap with reduced anxiety symptoms.
Vitality (6)
- Effect of a Combination of Magnesium, B Vitamins, Rhodiola, and Green Tea (L-Theanine) on Chronically Stressed Healthy Individuals-A Randomized, Placebo-Controlled Study
PubMed ID: 35565828
Combination supplement reduced stress and cold-pain sensitivity and improved daytime functionâbroad effects consistent with improved vitality for the formula.
- Rhodiola rosea in stress induced fatigue--a double blind cross-over study of a standardized extract SHR-5 with a repeated low-dose regimen on the mental performance of healthy physicians during night duty
PubMed ID: 11081987
Improved performance and reduced fatigue in nightâduty physicians indicates meaningful vitality improvements in stressful conditions.
- A randomized trial of two different doses of a SHR-5 Rhodiola rosea extract versus placebo and control of capacity for mental work
PubMed ID: 12725561
Large cadet study with strong antifatigue and mental performance effects supports increased vitality under acute stress.
- A randomised, double-blind, placebo-controlled, parallel-group study of the standardised extract shr-5 of the roots of Rhodiola rosea in the treatment of subjects with stress-related fatigue
PubMed ID: 19016404
Reduced burnout, improved attention and lower cortisol awakening response together reflect an increase in overall vitality in fatigued patients.
- [Three preparations of compound Chinese herbal medicines for de-adaptation to high altitude: a randomized, placebo-controlled trial]
PubMed ID: 21486552
Symptom relief across fatigue, attention and cardiorespiratory complaints after highâaltitude deâadaptation supports broader vitality benefits (large sample, subjective outcomes).
- The Effect of Short-Term Rhodiola rosea Supplementation on Simulated Game Time, Perceived Fatigue, and Performance in Basketball Players
PubMed ID: 41373984
Multi-week Rhodiola supplementation improved performance, recovery and antioxidant status in athletesâpractical vitality improvements.
Energy & Fatigue (6)
- [Three preparations of compound Chinese herbal medicines for de-adaptation to high altitude: a randomized, placebo-controlled trial]
PubMed ID: 21486552
Large singleâblind trial in soldiers deâadaptation reported symptom improvements including fatigue; subjective but sizable sample.
- Salidroside and exercise performance in healthy active young adults - an exploratory, randomized, double-blind, placebo-controlled study
PubMed ID: 39601362
Salidroside raised percent predicted VO2 during high-intensity intermittent exercise, consistent with increased physiological capacity/energy.
- The influence of adaptogens on ultraweak biophoton emission: a pilot-experiment
PubMed ID: 19170145
Small pilot RCT showed decreased selfâreported tiredness vs placebo (exploratory but positive).
- Rhodiola rosea in stress induced fatigue--a double blind cross-over study of a standardized extract SHR-5 with a repeated low-dose regimen on the mental performance of healthy physicians during night duty
PubMed ID: 11081987
Wellâdesigned doubleâblind crossover RCT found significant reductions in mental fatigue and improved cognitive performance during night duty.
- A randomized trial of two different doses of a SHR-5 Rhodiola rosea extract versus placebo and control of capacity for mental work
PubMed ID: 12725561
Large randomized doubleâblind trial showed a robust antifatigue index and improved mental work capacity vs placebo (highly significant).
- A randomised, double-blind, placebo-controlled, parallel-group study of the standardised extract shr-5 of the roots of Rhodiola rosea in the treatment of subjects with stress-related fatigue
PubMed ID: 19016404
Randomized trial in stressârelated fatigue reported significant reductions in burnout/fatigue vs placebo with objective attention improvements.
Stress resilience (6)
- Neuropeptide Y stimulation as primary target for preventive measures of maladaptative cardiovascular reactions in occupational chronic stress exposure
PubMed ID: 23272529
Adaptogen regimen altered cardiovascular responses to a stressor (multiâherb), consistent with stressâresponse modulation.
- The Effects of Rhodiola rosea L. Extract on Anxiety, Stress, Cognition and Other Mood Symptoms
PubMed ID: 26502953
Reported reductions in perceived stress and anxiety suggest an effect on psychological stress response in mildly anxious adults.
- A randomised, double-blind, placebo-controlled, parallel-group study of the standardised extract shr-5 of the roots of Rhodiola rosea in the treatment of subjects with stress-related fatigue
PubMed ID: 19016404
Reduced cortisol awakening response and improved burnout in stressârelated fatigue patients support effects on HPA axis/stress balancing.
- A randomized trial of two different doses of a SHR-5 Rhodiola rosea extract versus placebo and control of capacity for mental work
PubMed ID: 12725561
Antifatigue and improved mental work under stress support a balancing effect on stress response in cadets.
- Effect of a Combination of Magnesium, B Vitamins, Rhodiola, and Green Tea (L-Theanine) on Chronically Stressed Healthy Individuals-A Randomized, Placebo-Controlled Study
PubMed ID: 35565828
Combination formula lowered stress scores and cold pain sensitivity with durable effectsâevidence for improved stress-response balance for the combination.
- A combination of green tea, rhodiola, magnesium and B vitamins modulates brain activity and protects against the effects of induced social stress in healthy volunteers
PubMed ID: 33896388
Multi-ingredient supplement including Rhodiola moderated some physiological and EEG responses to acute social stress.
Focus & concentration (5)
- A randomized trial of two different doses of a SHR-5 Rhodiola rosea extract versus placebo and control of capacity for mental work
PubMed ID: 12725561
Large trial in cadets improved capacity for mental work and antifatigue index, indicating enhanced cognitive work performance.
- Rhodiola rosea in stress induced fatigue--a double blind cross-over study of a standardized extract SHR-5 with a repeated low-dose regimen on the mental performance of healthy physicians during night duty
PubMed ID: 11081987
Nightâduty RCT demonstrated significant improvements in attention/concentration tests with Rhodiola.
- Double-blind, placebo-controlled, randomised study of single dose effects of ADAPT-232 on cognitive functions
PubMed ID: 20374974
Singleâdose adaptogen mix containing Rhodiola improved attention/speed/accuracy 2 hours after dosing (multiâherb but positive cognitive signal).
- [Three preparations of compound Chinese herbal medicines for de-adaptation to high altitude: a randomized, placebo-controlled trial]
PubMed ID: 21486552
Reported improvements in attention/memory symptoms among soldiers after deâadaptation treatment with Rhodiola capsules.
- A randomised, double-blind, placebo-controlled, parallel-group study of the standardised extract shr-5 of the roots of Rhodiola rosea in the treatment of subjects with stress-related fatigue
PubMed ID: 19016404
Objective attention improvements (CCPT II indices) in stressârelated fatigue patients demonstrate enhanced mental focus.
Exercise recovery (5)
- Salidroside and exercise performance in healthy active young adults - an exploratory, randomized, double-blind, placebo-controlled study
PubMed ID: 39601362
Salidroside attenuated post-exercise myoglobin rise and prevented fatigue-inertia increasesâevidence for aiding recovery after high-intensity exercise.
- Rhodiola algida improves chemotherapy-induced oral mucositis in breast cancer patients
PubMed ID: 20374035
Faster hematologic recovery and reduced oral mucositis during chemotherapy indicate accelerated recovery after physiologic insult.
- The Effect of Short-Term Rhodiola rosea Supplementation on Simulated Game Time, Perceived Fatigue, and Performance in Basketball Players
PubMed ID: 41373984
Improved heart-rate recovery after simulated games and increased antioxidant markersâsupports faster physiological recovery in athletes.
- [Preventive and treatment effect of composite Rhodiolae on acute lung injury in patients with severe pulmonary hypertension during extracorporeal circulation]
PubMed ID: 14571608
Perioperative composite Rhodiola reduced acute lung injury rates and improved pulmonary markersâsupports improved surgical recovery outcomes (composite product).
- [Early use of Chinese drug rhodiola compound for patients with post-trauma and inflammation in prevention of ALI/ARDS]
PubMed ID: 11829830
Perioperative Rhodiolaâcontaining compound improved gas exchange and reduced ARDS occurrenceâsupports faster/safer postâoperative recovery (compound product).
Immune support (5)
- [Early use of Chinese drug rhodiola compound for patients with post-trauma and inflammation in prevention of ALI/ARDS]
PubMed ID: 11829830
Perioperative compound containing Rhodiola roughly halved ARDS rates and improved gas exchangeâconsistent with antiâinflammatory/immuneâmodulating benefit (compound product).
- [Effects of Rhodiola rosea injection on intrapulmonary shunt and blood IL-6 and TNF-α levels during single lung ventilation in patients undergoing radical resection of esophageal cancer]
PubMed ID: 38708504
Perioperative IV Rhodiola reduced IL-6 and TNF-α during single-lung ventilationâdirect anti-inflammatory/immunomodulatory signal.
- Rhodiola algida improves chemotherapy-induced oral mucositis in breast cancer patients
PubMed ID: 20374035
During chemotherapy Rhodiola algida was associated with faster WBC recovery and less oral mucositis, indicating immune/supportive effects.
- Impact of Chisan (ADAPT-232) on the quality-of-life and its efficacy as an adjuvant in the treatment of acute non-specific pneumonia
PubMed ID: 16323290
ADAPTâ232 (contains Rhodiola) shortened antibiotic duration in pneumonia and improved clinical recovery, suggesting immune support at population level.
- Complementary usage of Rhodiola crenulata (L.) in chronic obstructive pulmonary disease patients: the effects on cytokines and T cells
PubMed ID: 25403334
Randomized trial in COPD showed significant reductions in IFNâÎł, CD8+ T cells and hsâCRPâclear immunomodulatory/antiâinflammatory signal.
Endurance (5)
- The Effect of Short-Term Rhodiola rosea Supplementation on Simulated Game Time, Perceived Fatigue, and Performance in Basketball Players
PubMed ID: 41373984
VO2max increased and simulated-game completion times shortened in basketball players after 4 weeks of Rhodiolaâclear endurance improvements.
- Salidroside and exercise performance in healthy active young adults - an exploratory, randomized, double-blind, placebo-controlled study
PubMed ID: 39601362
Salidroside increased oxygen uptake during high-intensity intermittent exercise, supporting improved stamina.
- A randomized trial of two different doses of a SHR-5 Rhodiola rosea extract versus placebo and control of capacity for mental work
PubMed ID: 12725561
Antifatigue effects and improved mental work capacity may translate to better stamina under stress conditions.
- Effects of the Combined Supplementation of Caffeine and Rhodiola Rosea with Resistance Training on Lower Limb Explosive Power in Male Volleyball Players
PubMed ID: 40005009
Combined Rhodiola+caffeine enhanced repeated-jump and sustained jump performance in volleyball playersâstamina-related benefits (combination product).
- Dietary supplement with a combination of Rhodiola crenulata and Ginkgo biloba enhances the endurance performance in healthy volunteers
PubMed ID: 19568709
Rhodiola+Ginkgo trial increased VO2max from baseline more than placebo, suggesting endurance improvement (combined formula).
Relaxation (4)
- Clinical trial of Rhodiola rosea L. extract SHR-5 in the treatment of mild to moderate depression
PubMed ID: 17990195
Improvements in insomnia subscale and reduced somatic complaints in depressed patients suggest better relaxation/sleep onset.
- The Effects of Rhodiola rosea L. Extract on Anxiety, Stress, Cognition and Other Mood Symptoms
PubMed ID: 26502953
Subjects reported reduced stress and anxiety which can manifest as increased relaxation (open study without placebo).
- A randomised, double-blind, placebo-controlled, parallel-group study of the standardised extract shr-5 of the roots of Rhodiola rosea in the treatment of subjects with stress-related fatigue
PubMed ID: 19016404
Reduced burnout and cortisol awakening response imply decreased physiological hyperarousal and greater relaxation.
- Effect of a Combination of Magnesium, B Vitamins, Rhodiola, and Green Tea (L-Theanine) on Chronically Stressed Healthy Individuals-A Randomized, Placebo-Controlled Study
PubMed ID: 35565828
Combination product reduced DASS-42 stress and improved daytime dysfunction componentsâconsistent with increased relaxation in daily life.
Mental clarity (4)
- Rhodiola rosea in stress induced fatigue--a double blind cross-over study of a standardized extract SHR-5 with a repeated low-dose regimen on the mental performance of healthy physicians during night duty
PubMed ID: 11081987
Significant improvements in several cognitive/attention tasks during night duty indicate clearer cognitive function under stress.
- Double-blind, placebo-controlled, randomised study of single dose effects of ADAPT-232 on cognitive functions
PubMed ID: 20374974
Singleâdose adaptogen mix yielded shortâterm improvements in attention/speed/accuracy consistent with transient cognitive clarity gains.
- A randomized trial of two different doses of a SHR-5 Rhodiola rosea extract versus placebo and control of capacity for mental work
PubMed ID: 12725561
Improved mental work capacity in cadets supports sharper cognitive clarity during demanding tasks.
- A randomised, double-blind, placebo-controlled, parallel-group study of the standardised extract shr-5 of the roots of Rhodiola rosea in the treatment of subjects with stress-related fatigue
PubMed ID: 19016404
Objective attentional improvements in stressed patients reflect clearer cognitive processing.
Workout performance (4)
- Effects of the Combined Supplementation of Caffeine and Rhodiola Rosea with Resistance Training on Lower Limb Explosive Power in Male Volleyball Players
PubMed ID: 40005009
Rhodiola plus caffeine improved jump performance, sustained power and lowered RPE in trained volleyball players (combination design).
- Salidroside and exercise performance in healthy active young adults - an exploratory, randomized, double-blind, placebo-controlled study
PubMed ID: 39601362
Salidroside increased oxygen uptake and reduced muscle-damage marker after high-intensity intermittent exerciseâimproved exercise performance capacity.
- Dietary supplement with a combination of Rhodiola crenulata and Ginkgo biloba enhances the endurance performance in healthy volunteers
PubMed ID: 19568709
Rhodiola+Ginkgo increased VO2max versus placebo over 7 weeks (multiâherb formula) indicating improved aerobic performance.
- The Effect of Short-Term Rhodiola rosea Supplementation on Simulated Game Time, Perceived Fatigue, and Performance in Basketball Players
PubMed ID: 41373984
28-day randomized trial in basketball players found faster simulated-game times, improved VO2max and faster HR recoveryâmeaningful performance gains.
Healthy aging (2)
- [Effect of rhodiola on serum troponin 1, cardiac integral backscatter and left ventricle ejective fraction of patients who received epirubicin-contained chemotherapy]
PubMed ID: 21302483
Cardioprotective effects (lower troponin, preserved LVEF) during chemo suggest tissue protection relevant to healthy aging.
- Protective effects of salidroside on epirubicin-induced early left ventricular regional systolic dysfunction in patients with breast cancer
PubMed ID: 22770377
Salidroside limited ROS rise and preserved regional systolic functionâdirect antioxidant/cardioprotective data supportive of antiâaging mechanisms.
Motivation & confidence (1)
- A randomized trial of two different doses of a SHR-5 Rhodiola rosea extract versus placebo and control of capacity for mental work
PubMed ID: 12725561
Improved mental work capacity and antifatigue index in cadets could translate to increased motivation under task stress.
Sleep quality (1)
- Clinical trial of Rhodiola rosea L. extract SHR-5 in the treatment of mild to moderate depression
PubMed ID: 17990195
Depression trial reported improvements on insomnia subscale with SHRâ5 vs placebo.
Similar by evidence
Supplements the same benefits carry qualifying findings for â a fact about the evidence graph, not a recommendation to swap.
Products with Rhodiola Rosea
Search all380 products whose verified label declares Rhodiola Rosea â not every bottle that mentions it in a title.
Being studied right now
Recruiting clinical trials registered on ClinicalTrials.gov. A trial in progress has no result yet â this is what the field is asking, not what it found.