Skullcap
11 benefits mapped to clinical evidence across supplements.
Dose per serving from products
58 products in our catalogue print how much Skullcap a serving holds.
Most common: 50 mg to 100 mg, 31% of 58 products.
| Dose per serving | Products |
|---|---|
| 10 mg or less | 1 |
| 10 mg to 25 mg | 7 |
| 25 mg to 50 mg | 3 |
| 50 mg to 100 mg | 18 |
| 100 mg to 250 mg | 8 |
| 250 mg to 500 mg | 11 |
| 500 mg to 1 g | 8 |
| over 1 g | 2 |
Benefit Evidence
Research sources
Mood balance (4)
- American Skullcap (Scutellaria lateriflora): a randomised, double-blind placebo-controlled crossover study of its effects on mood in healthy volunteers
PubMed ID: 23878109
American skullcap produced a highly significant decrease in POMS total mood disturbance among healthy volunteers.
- Efficacy and Tolerability of a Chemically Characterized Scutellaria lateriflora L. Extract-Based Food Supplement for Sleep Management: A Single-Center, Controlled, Randomized, Crossover, Double-Blind Clinical Trial
PubMed ID: 40362800
Sleep improvements and reduced sleep latency with S. lateriflora are consistent with a calmer mood and reduced nighttime arousal.
- Effects of a Scutellaria baicalensis/Crataegus laevigata, magnesium and chromium supplement on stressed individuals: A randomised, double-blind, placebo-controlled, crossover trial
PubMed ID: 41194549
Supplement containing Scutellaria reduced trait anxiety and POMS disturbance in stressed adults, indicating calmer mood.
- The Effects of Combined Scutellaria and Saffron Supplementation on Mood Regulation in Participants with Mild-to-Moderate Depressive Symptoms: A Randomized, Double-Blind, Placebo-Controlled Study
PubMed ID: 40077679
Six‑week RCT of saffron and scutellaria extracts produced modest improvements in depression/anxiety/wellbeing measures versus placebo (placebo responses substantial).
Stress & Anxiety (3)
- American Skullcap (Scutellaria lateriflora): a randomised, double-blind placebo-controlled crossover study of its effects on mood in healthy volunteers
PubMed ID: 23878109
American skullcap improved overall mood (large POMS effect), compatible with a gentle calming action in mildly anxious participants.
- Effects of a Scutellaria baicalensis/Crataegus laevigata, magnesium and chromium supplement on stressed individuals: A randomised, double-blind, placebo-controlled, crossover trial
PubMed ID: 41194549
Multi‑ingredient supplement reduced trait anxiety in stressed adults; Scutellaria may contribute.
- Efficacy and Tolerability of a Chemically Characterized Scutellaria lateriflora L. Extract-Based Food Supplement for Sleep Management: A Single-Center, Controlled, Randomized, Crossover, Double-Blind Clinical Trial
PubMed ID: 40362800
Sleep quality and latency improvements in insomnia patients indicate a clinically meaningful calming/sedative effect at bedtime.
Immune support (2)
- [The effect of he jie decoction on the TCRV beta 7 of chronic hepatitis B patients]
PubMed ID: 12583341
Multi‑herb decoction containing Scutellaria increased a measured immune marker (TCRV beta7) and had higher apparent response in chronic hepatitis B patients.
- The safety of flavocoxid, a medical food, in the dietary management of knee osteoarthritis
PubMed ID: 19857081
Flavonoid medical food containing Scutellaria had fewer upper respiratory adverse events vs placebo, suggesting an immune‑related safety signal.
Relaxation (2)
- Efficacy and Tolerability of a Chemically Characterized Scutellaria lateriflora L. Extract-Based Food Supplement for Sleep Management: A Single-Center, Controlled, Randomized, Crossover, Double-Blind Clinical Trial
PubMed ID: 40362800
Crossover RCT in mild–moderate insomnia showed improved sleep quality and reduced sleep latency — consistent with relaxation effect.
- Effects of a Scutellaria baicalensis/Crataegus laevigata, magnesium and chromium supplement on stressed individuals: A randomised, double-blind, placebo-controlled, crossover trial
PubMed ID: 41194549
Multi‑ingredient supplement containing Scutellaria reduced trait anxiety and improved mood in stressed adults; multi‑ingredient limits attribution.
Sleep quality (2)
- Efficacy and Tolerability of a Chemically Characterized Scutellaria lateriflora L. Extract-Based Food Supplement for Sleep Management: A Single-Center, Controlled, Randomized, Crossover, Double-Blind Clinical Trial
PubMed ID: 40362800
Crossover RCT in mild–moderate insomnia improved PSQI, decreased sleep latency and increased total sleep time with S. lateriflora extract.
- Effects of a Scutellaria baicalensis/Crataegus laevigata, magnesium and chromium supplement on stressed individuals: A randomised, double-blind, placebo-controlled, crossover trial
PubMed ID: 41194549
Multi‑ingredient supplement (contains Scutellaria) increased total sleep time and improved sleep measures in stressed adults.
Detoxification (1)
- [A multicenter randomized controlled study on the efficacy and safety of Yinzhihuang oral solution for the treatment of neonatal indirect hyperbilirubinemia in term newborn infants]
PubMed ID: 22176900
Yinzhihuang solution (contains Scutellaria) plus phototherapy increased bilirubin reduction and reduced phototherapy need in neonatal jaundice—supports hepatic/bilirubin clearance.
Digestive support (1)
- [Application of dannang recipe no. 2 in the perioperative stage of laparoscopic cholecystectomy]
PubMed ID: 19317164
Multi‑herb recipe including Scutellaria significantly sped recovery of bowel function after gallbladder surgery (time to bowel sounds, flatus, defecation).
Skin health (1)
- [Clinical observation on auxiliary treatment of hormone dependence dermatitis by shufeng liangxue decoction]
PubMed ID: 19317172
Herbal decoction including Scutellaria plus standard care produced higher cure rates and lower 3‑month relapse in hormone‑dependent dermatitis (clinical skin benefit).
Respiratory comfort (1)
- [Clinical comparative study of intravenous piperacillin sodium or injection of scutellaria compound in patients with pulmonary infection]
PubMed ID: 2208421
In pneumonia patients a Scutellaria compound injection had similar clinical efficacy to piperacillin suggesting respiratory benefit in infection context (compound product).
Antioxidant (1)
- [Huangqin Qingre Chubi Capsules in improving oxidative stress of patients with ankylosing spondylitis via activating PPARγ mediated AMPK/FOXO3a pathway]
PubMed ID: 32237331
HQC capsules (contain Scutellaria) increased SOD/TAOC and decreased MDA in patients with ankylosing spondylitis; multi‑herb product limits attribution.
Stress resilience (1)
- Effects of a Scutellaria baicalensis/Crataegus laevigata, magnesium and chromium supplement on stressed individuals: A randomised, double-blind, placebo-controlled, crossover trial
PubMed ID: 41194549
Crossover RCT in stressed adults showed improved trait anxiety, mood, sleep and stress‑era cognitive performance with a supplement containing Scutellaria.
Similar by evidence
Supplements the same benefits carry qualifying findings for — a fact about the evidence graph, not a recommendation to swap.
Products with Skullcap
Search all211 products whose verified label declares Skullcap — not every bottle that mentions it in a title.