Panax Ginseng
18 benefits mapped to clinical evidence across supplements.
Dose per serving from products
147 products in our catalogue print how much Panax Ginseng a serving holds.
Most common: 25 mg to 50 mg, 25% of 147 products.
| Dose per serving | Products |
|---|---|
| 2.5 mg or less | 1 |
| 2.5 mg to 5 mg | 15 |
| 5 mg to 10 mg | 3 |
| 10 mg to 25 mg | 18 |
| 25 mg to 50 mg | 37 |
| 50 mg to 100 mg | 24 |
| 100 mg to 250 mg | 32 |
| 250 mg to 500 mg | 13 |
| over 500 mg | 4 |
Dose per serving from research
82 study groups in 59 studies say how much Panax Ginseng participants took a day.
These are the doses the studies gave. They are not a recommendation.
Most common: 2.5 g to 5 g, 34% of 82 study groups.
| Daily dose | Study groups |
|---|---|
| 100 mg or less | 4 |
| 100 mg to 250 mg | 10 |
| 250 mg to 500 mg | 5 |
| 500 mg to 1 g | 10 |
| 1 g to 2.5 g | 15 |
| 2.5 g to 5 g | 28 |
| 5 g to 10 g | 9 |
| over 10 g | 1 |
Commonly used together
8 of 82 study groups took Panax Ginseng with something else. Shown: what 3 or more different studies gave.
What was given together, not what works together.
| Taken with | Study groups |
|---|---|
| Ginkgo Biloba | 4 |
Benefit Evidence
Attention/memory +fast
Lower fatigue/stress -4.3
ADHD symptoms -2.25
Research sources
Illness recovery (20)
- Effects of Astragalus membranaceus and Panax notoginseng Saponins Extract on the Pharmacokinetics of Whey Protein Absorption, Intestinal Permeability, and Muscle Function: A Pilot Study
PubMed ID: 41683325
Panax notoginseng saponins increased amino acid (BCAA) absorption and produced small grip‑strength gains, suggesting improved nutritional recovery potential.
- Efficacy and Safety of "URSA Complex" in Subjects with Physical Fatigue: A Multicenter, Randomized, Double-blind, Placebo-controlled Trial
PubMed ID: 26830981
Multi‑ingredient pill including dried ginseng increased the proportion crossing below a fatigue cutoff vs placebo, implying faster symptomatic recovery from fatigue.
- Improvement of hematoma absorption and neurological function in patients with acute intracerebral hemorrhage treated with Xueshuantong
PubMed ID: 23062408
Herbal injection containing Panax components sped hematoma absorption and improved NIHSS after intracerebral hemorrhage, indicating faster neurological/structural recovery.
- Effect of Red Ginseng on Genotoxicity and Health-Related Quality of Life after Adjuvant Chemotherapy in Patients with Epithelial Ovarian Cancer: A Randomized, Double Blind, Placebo-Controlled Trial
PubMed ID: 28753932
Red ginseng reduced genotoxic marker and improved several QoL subscales post‑chemotherapy, consistent with improved recovery/rehabilitation.
- A new way: alleviating postembolization syndrome following transcatheter arterial chemoembolization
PubMed ID: 19216654
Addition of ginsenosides reduced post‑TACE symptoms (nausea/vomiting/fever) and improved liver tests, consistent with faster postprocedural recovery.
- [The effect of salvia miltiorrhiza and shengmai on inflammatory mediator and renal function of post-operative patients with obstructive jaundice]
PubMed ID: 12528557
Shengmai (contains ginseng) in post‑op patients reduced inflammation and improved renal markers—consistent with faster clinical recovery (multi‑component product).
- [Effect of Shenfu injection in postoperative recovery after abdominal surgery]
PubMed ID: 17455472
Shenfu injection (contains ginseng) shortened time to first gas after abdominal surgery and improved postoperative indices — relevant to faster postoperative recovery.
- [Effect of Panax notoginseng saponins on serum neuronal specific enolase and rehabilitation in patients with cerebral hemorrhage]
PubMed ID: 17343007
Adjunct PNS reduced NSE and improved NIHSS/Barthel after cerebral hemorrhage — direct functional recovery signal.
- Cardioprotection of Shenfu Injection against myocardial ischemia/reperfusion injury in open heart surgery
PubMed ID: 18568324
Shenfu Injection (contains ginseng) reduced perioperative myocardial injury markers and improved antioxidant status — supports quicker postop cardiac recovery.
- The beneficial effects of Kampo medicine Dai-ken-chu-to after hepatic resection: a prospective randomized control study
PubMed ID: 23435143
Dai-kenchu-to (contains ginseng) shortened time to first flatus/bowel movement and reduced post-op inflammation → clear perioperative recovery benefit.
- Radix/rhizoma notoginseng extract (sanchitongtshu) for ischemic stroke: a randomized controlled study
PubMed ID: 21094030
Panax notoginseng extract added to aspirin improved neurological deficit and ADL after ischemic stroke — improved recovery outcomes.
- Red ginseng extract improves coronary flow reserve and increases absolute numbers of various circulating angiogenic cells in patients with first ST-segment elevation acute myocardial infarction
PubMed ID: 20641058
Post-MI trial showed improved coronary flow reserve and angiogenic cells over 8 months, suggesting enhanced cardiac recovery.
- Daikenchuto stimulates colonic motility after laparoscopic-assisted colectomy
PubMed ID: 24895799
Randomized trial showed daikenchuto accelerated return of bowel function after colectomy (earlier flatus/bowel movement).
- Ginsenoside Rd Is Efficacious Against Acute Ischemic Stroke by Suppressing Microglial Proteasome-Mediated Inflammation
PubMed ID: 26081140
Pooled trials of ginsenoside Rd improved functional/neurological outcomes after acute ischemic stroke, consistent with faster recovery.
- The effects of the herbal medicine Daikenchuto (TJ-100) after esophageal cancer resection, open-label, randomized controlled trial
PubMed ID: 29892933
Daikenchuto after esophagectomy reduced postoperative weight loss (clinically relevant) → meaningful recovery benefit though multi‑component.
- Effect of herbal medicine daikenchuto on oral and enteral caloric intake after liver transplantation: A multicenter, randomized controlled trial
PubMed ID: 29747091
Daikenchuto sped return to oral/enteral intake and increased portal flow after liver transplant → clear postoperative recovery effect (multi‑herb formula).
- Efficacy and Safety of Panax notoginseng Saponins in the Treatment of Adults With Ischemic Stroke in China: A Randomized Clinical Trial
PubMed ID: 37338907
Large RCT of Panax notoginseng saponins increased functional independence after ischemic stroke — direct evidence of improved functional recovery.
- [Effects of Yiqi Huoxue Jiedu formula on the gut microbiota in elderly patients with pulmonary-derived sepsis based on 16S rDNA sequencing: a multicenter prospective randomized double-blind controlled trial]
PubMed ID: 40819941
Yiqi Huoxue Jiedu formula (contains Panax) reduced PCT and APACHE II vs control in elderly sepsis patients, indicating more rapid clinical improvement.
- Evaluation of TU-100 (Daikenchuto), a Traditional Japanese Kampo Medicine, as an Adjunct to Enhanced Recovery After Surgery, for Acceleration of Gastrointestinal Recovery After Bowel Resection: Results of a Proof-of-Concept, Phase 2, Randomized, Double-Blinded, Placebo-Controlled Trial
PubMed ID: 41114550
Daikenchuto (contains ginseng) shortened median LOS by ~1 day and increased early GI recovery (POD2) in bowel resection patients.
- [Effect of yiqi wenyang huoxue recipe on bone marrow stem cells' mobilization and its influence on heart function in patients with myocardial infarction]
PubMed ID: 19317161
Herbal recipe with ginseng increased CD34+ mobilization and produced smaller infarct / higher LVEF after MI — supports faster cardiac recovery.
Blood circulation (16)
- The efficacy of Chinese herbal medicines on acute coronary syndrome with renal insufficiency after percutaneous coronary intervention
PubMed ID: 31689480
Herbal capsules (one includes American ginseng) reduced cardiac events after PCI—clinical cardiovascular benefit (multi‑ingredient).
- Red ginseng extract improves coronary flow reserve and increases absolute numbers of various circulating angiogenic cells in patients with first ST-segment elevation acute myocardial infarction
PubMed ID: 20641058
Red ginseng increased coronary flow reserve and angiogenic cell counts in post-MI patients — direct microvascular circulation benefit.
- Efficacy and safety of Korean red ginseng for cold hypersensitivity in the hands and feet: a randomized, double-blind, placebo-controlled trial
PubMed ID: 25284751
8‑week RCT in women with cold hypersensitivity increased peripheral skin temperatures and reduced symptoms — objective peripheral circulation improvement.
- Ginsenoside Rd Is Efficacious Against Acute Ischemic Stroke by Suppressing Microglial Proteasome-Mediated Inflammation
PubMed ID: 26081140
Pooled data of ginsenoside Rd showed improved outcomes after ischemic stroke, consistent with vascular/neuroprotective effects.
- Blood pressure-lowering effect of Korean red ginseng associated with decreased circulating Lp-PLA2 activity and lysophosphatidylcholines and increased dihydrobiopterin level in prehypertensive subjects
PubMed ID: 26843120
Korean red ginseng produced clinically meaningful systolic/diastolic BP reductions (~6.5/5 mmHg) and improved vascular biomarkers → strong circulation signal.
- Effect of herbal medicine daikenchuto on oral and enteral caloric intake after liver transplantation: A multicenter, randomized controlled trial
PubMed ID: 29747091
Daikenchuto increased portal venous flow volume/velocity after liver transplant → objective circulation improvement (multi‑herb product).
- Xinyue Capsule in patients with stable coronary artery disease after percutaneous coronary intervention: a multicenter, randomized, placebo-controlled trial
PubMed ID: 32446979
Panax quinquefolius saponins (Xinyue) added to conventional therapy significantly reduced major cardiac events after PCI — strong cardiovascular/circulatory benefit.
- Efficacy and Safety of Panax notoginseng Saponins in the Treatment of Adults With Ischemic Stroke in China: A Randomized Clinical Trial
PubMed ID: 37338907
Panax notoginseng saponins increased functional independence after ischemic stroke — direct cerebrovascular benefit indicating improved circulation/outcomes.
- Efficacy of Xueshuantong Injection in Reducing Residual Inflammatory Risk in Unstable Angina Patients: A Randomized Double-Blind Controlled Trial
PubMed ID: 41111082
Xueshuantong injection (Panax notoginseng-derived) lowered inflammatory markers and improved symptoms in unstable angina—relevant to vascular health/circulation.
- Vascular effects of combined enriched Korean Red ginseng (Panax Ginseng) and American ginseng (Panax Quinquefolius) administration in individuals with hypertension and type 2 diabetes: A randomized controlled trial
PubMed ID: 32147072
Combined Korean red + American ginseng lowered central systolic BP and pulse waveform parameters in diabetics—favorable hemodynamic effects.
- [Effect of yiqi wenyang huoxue recipe on bone marrow stem cells' mobilization and its influence on heart function in patients with myocardial infarction]
PubMed ID: 19317161
Treatment increased peripheral CD34+ mobilization and improved LVEF and infarct size post‑MI — clear cardiovascular/hemodynamic benefit.
- [Clinical study on effect of Shenmai Injection in treating congestive heart failure]
PubMed ID: 14666758
Shenmai Injection (contains ginseng) added to routine care improved heart function and hemodynamic/blood markers in chronic heart failure patients.
- Effect of American ginseng (Panax quinquefolius L.) on arterial stiffness in subjects with type-2 diabetes and concomitant hypertension
PubMed ID: 23973636
3 g/day American ginseng for 12 weeks markedly reduced systolic BP and lowered radial augmentation index (arterial stiffness) in T2D hypertensives.
- Effects of huoxin formula on the arterial functions of patients with coronary heart disease
PubMed ID: 31199705
Adjunct Huoxin formula (includes Panax notoginseng) improved IMT, ABI, CAVI and reduced inflammatory markers in CHD patients.
- Combination of Panax notoginseng saponins and aspirin potentiates platelet inhibition with alleviated gastric injury via modulating arachidonic acid metabolism
PubMed ID: 33370633
Adding Panax notoginseng saponins to aspirin enhanced platelet inhibition and reduced aspirin‑induced gastric injury, showing strong effects on platelet/vascular markers (related species).
- [Effect of Radix notoginseng saponins on platelet activating molecule expression and aggregation in patients with blood hyperviscosity syndrome]
PubMed ID: 15143716
Panax notoginseng saponins reduced platelet activation/aggregation and modified vasoactive mediators, indicating improved blood flow/hemorheology (related Panax species).
Wellbeing (20)
- Shenfu decoction as adjuvant therapy for improving quality of life and hepatic dysfunction in patients with symptomatic chronic heart failure
PubMed ID: 25937255
Shenfu (contains ginseng) improved MLHFQ QoL scores in chronic heart failure patients versus control (direct QoL measure).
- Effect of Red Ginseng on Genotoxicity and Health-Related Quality of Life after Adjuvant Chemotherapy in Patients with Epithelial Ovarian Cancer: A Randomized, Double Blind, Placebo-Controlled Trial
PubMed ID: 28753932
Red ginseng improved multiple HRQL subscales and reduced a genotoxic marker in cancer survivors, indicating meaningful QoL benefits.
- Phyto-Female Complex for the relief of hot flushes, night sweats and quality of sleep: randomized, controlled, double-blind pilot study
PubMed ID: 17454163
3‑month multi‑herb formula including American ginseng markedly reduced hot flashes/night sweats and improved sleep in menopausal women → strong QoL signals.
- [American ginseng compound liquor on retarding-aging process]
PubMed ID: 1954661
Older adults reported symptomatic improvement with an American ginseng compound drink (subjective well‑being benefits).
- Effect of Memo®, a natural formula combination, on Mini-Mental State Examination scores in patients with mild cognitive impairment
PubMed ID: 23950642
Ginkgo+Panax+royal jelly in MCI improved MMSE and likely patient/caregiver‑observed function—benefit to overall well‑being (combination).
- Double-blind study of a multivitamin complex supplemented with ginseng extract
PubMed ID: 9034759
Pharmaton (multivitamin + G115) improved quality‑of‑life more than multivitamin alone — suggests ginseng contributes to overall well‑being in that formulation.
- Effects of Panax ginseng on quality of life
PubMed ID: 11895046
Short‑term (4‑week) improvements in SF‑36 mental/social domains and mental component summary, though effects faded by 8 weeks.
- Effects of sun ginseng on subjective quality of life in cancer patients: a double-blind, placebo-controlled pilot trial
PubMed ID: 16882101
Sun ginseng improved psychological domain WHOQOL and GHQ‑12 scores in cancer patients over 12 weeks (subjective overall well‑being gains).
- [Clinical study on effect of total panax notoginseng saponins on immune related inner environment imbalance in rheumatoid arthritis patients]
PubMed ID: 17717913
Reduced inflammation and improved joint symptoms in RA patients likely improved quality of life/overall well‑being.
- Effects of red ginseng supplementation on menopausal symptoms and cardiovascular risk factors in postmenopausal women: a double-blind randomized controlled trial
PubMed ID: 22027944
Menopausal symptom scores improved along with lipid and carotid changes — meaningful QoL effects in postmenopausal women.
- Ginseng in the treatment of fatigue in multiple sclerosis: a randomized, placebo-controlled, double-blind pilot study
PubMed ID: 23301896
3-month RCT in female MS patients showed significant QoL (MSQOL-54) improvement with ginseng.
- Adjuvant effects of fermented red ginseng extract on advanced non-small cell lung cancer patients treated with chemotherapy
PubMed ID: 26142337
Fermented red ginseng improved fatigue and reduced chemo toxicity → improved patient‑reported well‑being as an adjunct.
- A randomized, double-blind, multicenter, placebo-controlled clinical study on the efficacy and safety of Shenmai injection in patients with chronic heart failure
PubMed ID: 27045864
Shenmai injection improved NYHA class, 6MWD and SF‑36 QoL short‑term → meaningful QoL/well‑being signal (multi‑herb).
- [A multicenter, large-sample, randomized clinical trial on improving the median survival time of advanced non-small cell lung cancer by combination of Ginseng Rg3 and chemotherapy]
PubMed ID: 29730918
Ginseng Rg3 addition improved survival and KPS in advanced NSCLC → improved clinical well‑being and performance status.
- The effect of ginseng on sexual dysfunction in menopausal women: A double-blind, randomized, controlled trial
PubMed ID: 31331583
Panax ginseng in postmenopausal women improved sexual function and MENQOL → clear QoL/well‑being benefit.
- A Phase II Randomized Controlled Trial of Renshen Yangrong Tang Herbal Extract Granules for Fatigue Reduction in Cancer Survivors
PubMed ID: 31668965
Multi‑herb RSYRT (includes ginseng) produced large, clinically meaningful fatigue and QoL improvements in cancer survivors.
- Korean red ginseng for cancer-related fatigue in colorectal cancer patients with chemotherapy: A randomised phase III trial
PubMed ID: 32172198
Large trial reported QoL/fatigue domain improvements (mood, walking) with Korean red ginseng during chemo, reflecting overall well‑being gains.
- Effects of Panax Ginseng on Health-Related Quality of Life in Patients with Non-Metastatic Breast Cancer: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial Ginseng for HRQOL in Breast Cancer
PubMed ID: 37218691
In women receiving chemotherapy, ginseng largely prevented decline across multiple quality‑of‑life domains (physical, social, emotional).
- Effect of Hydroponically Grown Red Panax Ginseng on Perceived Stress Level, Emotional Processing, and Cognitive Functions in Moderately Stressed Adults: A Randomized, Double-Blind, Placebo-Controlled Study
PubMed ID: 40289951
Hydroponic red ginseng reduced perceived stress and negative affect and improved cognitive latency, improving well‑being.
- Ginseng Berry Concentrate Alleviates Fatigue in Humans: A Randomized, Placebo-Controlled, Double-Blinded Clinical Trial
PubMed ID: 41022533
Ginseng berry reduced fatigue severity and resting lactic acid, contributing to improved daily well‑being.
Energy & Fatigue (16)
- The Effects of Korean Red Ginseng on Biological Aging and Antioxidant Capacity in Postmenopausal Women: A Double-Blind Randomized Controlled Study
PubMed ID: 34578969
8-week RCT in postmenopausal women increased mitochondrial marker, antioxidant status and significantly reduced fatigue severity.
- Korean red ginseng for cancer-related fatigue in colorectal cancer patients with chemotherapy: A randomised phase III trial
PubMed ID: 32172198
Phase III trial showed meaningful reductions in cancer-related fatigue and improvements in related QoL domains during chemotherapy.
- A Phase II Randomized Controlled Trial of Renshen Yangrong Tang Herbal Extract Granules for Fatigue Reduction in Cancer Survivors
PubMed ID: 31668965
Multi‑herb formula containing Renshen produced large, clinically meaningful fatigue reductions in cancer survivors (phase II RCT) → strong effect though multi‑ingredient.
- Anti-Fatigue Effects of Enzyme-Modified Ginseng Extract: A Randomized, Double-Blind, Placebo-Controlled Trial
PubMed ID: 27754709
Enzyme‑modified ginseng lowered VAS fatigue scores over 4 weeks (RCT) → moderate‑strong anti‑fatigue signal.
- Adjuvant effects of fermented red ginseng extract on advanced non-small cell lung cancer patients treated with chemotherapy
PubMed ID: 26142337
Fermented red ginseng adjunct to chemotherapy significantly improved patient‑reported fatigue (FSI) → strong evidence for fatigue reduction in this setting.
- Wisconsin Ginseng (Panax quinquefolius) to improve cancer-related fatigue: a randomized, double-blind trial, N07C2
PubMed ID: 23853057
Large multicenter RCT: American ginseng 2 g/day significantly improved cancer-related fatigue at 8 weeks.
- Ginseng in the treatment of fatigue in multiple sclerosis: a randomized, placebo-controlled, double-blind pilot study
PubMed ID: 23301896
3-month RCT in female MS patients showed reduced fatigue (MFIS) and improved QoL vs placebo.
- Effects of tissue-cultured mountain ginseng (Panax ginseng CA Meyer) extract on male patients with erectile dysfunction
PubMed ID: 19234482
Improved erectile function and satisfaction often correlates with increased subjective vitality.
- Pilot study of Panax quinquefolius (American ginseng) to improve cancer-related fatigue: a randomized, double-blind, dose-finding evaluation: NCCTG trial N03CA
PubMed ID: 19415341
Large American ginseng trial found no overall benefit but a suggestive, clinically relevant improvement in higher-dose subgroup for cancer-related fatigue.
- Single doses of Panax ginseng (G115) reduce blood glucose levels and improve cognitive performance during sustained mental activity
PubMed ID: 15982990
Reported reduced subjective mental fatigue after a single dose (200 mg) in an acute study.
- Efficacy and Safety of "URSA Complex" in Subjects with Physical Fatigue: A Multicenter, Randomized, Double-blind, Placebo-controlled Trial
PubMed ID: 26830981
Multi‑ingredient product containing ginseng increased the proportion of participants crossing below a fatigue cutoff compared with placebo.
- Antifatigue effects of Panax ginseng C.A. Meyer: a randomised, double-blind, placebo-controlled trial
PubMed ID: 23613825
Well‑powered RCT in chronic fatigue showed significant reductions in oxidative stress markers and improvements in mental fatigue with Panax ginseng.
- Effect of Red Ginseng on Genotoxicity and Health-Related Quality of Life after Adjuvant Chemotherapy in Patients with Epithelial Ovarian Cancer: A Randomized, Double Blind, Placebo-Controlled Trial
PubMed ID: 28753932
Red ginseng improved fatigue‑related QoL subscales in ovarian cancer patients post‑chemotherapy.
- A randomized, placebo-controlled trial investigating the acute and chronic benefits of American Ginseng (Cereboost®) on mood and cognition in healthy young adults, including in vitro investigation of gut microbiota changes as a possible mechanism of action
PubMed ID: 34396468
American ginseng reduced subjective mental fatigue and improved some mood/self‑assurance measures in healthy adults.
- Short-Term Panax Ginseng Extract Supplementation Reduces Fasting Blood Triacylglycerides and Oxygen Consumption during Sub-Maximal Aerobic Exercise in Male Recreational Athletes
PubMed ID: 38785940
Short‑term Panax reduced VO2 and energy cost during submaximal exercise, implying improved energetic efficiency.
- Ginseng Berry Concentrate Alleviates Fatigue in Humans: A Randomized, Placebo-Controlled, Double-Blinded Clinical Trial
PubMed ID: 41022533
Ginseng berry concentrate reduced multiple fatigue scales and lowered resting lactic acid in adults with daily fatigue.
Healthy aging (16)
- Effect of American ginseng (Panax quinquefolius L.) on arterial stiffness in subjects with type-2 diabetes and concomitant hypertension
PubMed ID: 23973636
American ginseng lowered arterial stiffness and systolic BP in hypertensive type‑2 diabetics—cardiovascular risk reduction relevant to healthy aging.
- The Effects of Korean Red Ginseng on Biological Aging and Antioxidant Capacity in Postmenopausal Women: A Double-Blind Randomized Controlled Study
PubMed ID: 34578969
Increased mtDNA copy number and antioxidant status in postmenopausal women indicate biologically plausible anti‑aging effects.
- The effect of Korean Red Ginseng on sarcopenia biomarkers in type 2 diabetes patients
PubMed ID: 32470863
Improvements in sarcopenia-related biomarkers (follistatin, SHBG, GDF-15) relevant to muscle aging in older women.
- Impact of extended ginsenoside Rb1 on early chronic kidney disease: a randomized, placebo-controlled study
PubMed ID: 27853891
Ginsenoside Rb1 slowed kidney function decline and reduced oxidative stress/inflammation in early CKD → supports mechanisms relevant to healthy aging.
- Effects of ginseng on peripheral blood mitochondrial DNA copy number and hormones in men with metabolic syndrome: A randomized clinical and pilot study
PubMed ID: 26860800
In men with metabolic syndrome, RG raised leukocyte mtDNA copy number (mitochondrial marker) and testosterone—biologic signals relevant to healthy aging.
- Antioxidative effects of Korean red ginseng in postmenopausal women: a double-blind randomized controlled trial
PubMed ID: 24814037
12‑week RCT showed red ginseng increased antioxidant SOD activity, suggesting anti‑oxidative/aging‑related effects.
- Beneficial effects of Korean red ginseng on lymphocyte DNA damage, antioxidant enzyme activity, and LDL oxidation in healthy participants: a randomized, double-blind, placebo-controlled trial
PubMed ID: 22805313
Korean red ginseng increased antioxidant enzymes and decreased oxidative damage in healthy adults (RCT), relevant to aging biology.
- Antioxidant effects of Panax ginseng C.A. Meyer in healthy subjects: a randomized, placebo-controlled clinical trial
PubMed ID: 21699953
4-week RCT in healthy volunteers showed decreased ROS/MDA and increased glutathione-related activity — supports anti-oxidative aging mechanisms.
- Non-organ-specific preventive effect of long-term administration of Korean red ginseng extract on incidence of human cancers
PubMed ID: 20521975
3‑year red ginseng trial showed reduced cancer incidence in males — long‑term disease‑prevention signal relevant to healthy aging.
- Panax ginseng enhances cognitive performance in Alzheimer disease
PubMed ID: 18580589
Short‑term cognitive improvements in AD and reversal on stopping suggest potential age-related cognitive support.
- [American ginseng compound liquor on retarding-aging process]
PubMed ID: 1954661
American ginseng compound in older adults improved aging‑related symptom scores and antioxidant markers (directly relevant to healthy aging).
- Red ginseng root extract mixed with Torilus fructus and Corni fructus improves facial wrinkles and increases type I procollagen synthesis in human skin: a randomized, double-blind, placebo-controlled study
PubMed ID: 20041778
Red ginseng‑containing mixture improved wrinkle appearance and increased type I procollagen, indicating anti‑aging effects on skin.
- Effects of ginseng berry saponins from panax ginseng on glucose metabolism of patients with prediabetes: A randomized, double-blinded, placebo-controlled, crossover trial
PubMed ID: 39004031
Ginseng berry saponin improved glucose handling and HDL in prediabetes, beneficial for metabolic aspects of healthy aging.
- Effects of huoxin formula on the arterial functions of patients with coronary heart disease
PubMed ID: 31199705
Huoxin formula (includes Panax notoginseng) improved arterial stiffness/IMT and lowered inflammatory markers in CHD patients—cardiovascular aging endpoints.
- Efficacy and Safety of Panax ginseng Sprout Extract in Subjective Memory Impairment: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial
PubMed ID: 38931306
Improved verbal memory, global cognition, and reduced AChE in older adults with subjective memory complaints supports cognitive aging benefits.
- Efficacy and safety of red ginseng extract powder (KGC05pg) in achieving glycemic control in prediabetic Korean adults: A 12-week, single-center, randomized, double-blind, parallel-group, placebo-controlled study
PubMed ID: 39969290
Korean red ginseng improved glycemic markers and insulin resistance in prediabetic adults, supporting metabolic health with aging.
Immune support (14)
- Effects of a new nutraceutical ingredient on allergen-induced sulphidoleukotrienes production and CD63 expression in allergic subjects
PubMed ID: 18817894
Multi‑herb supplement (includes Panax) significantly inhibited leukotriene production and basophil activation in allergic patients after 10 days.
- Immunomodulatory effects of two extracts of Panax ginseng C.A. Meyer
PubMed ID: 2100737
Randomized double‑blind trial showed enhanced neutrophil chemotaxis, phagocytosis and intracellular killing after 4–8 weeks of Panax ginseng extracts — supports cellular immune enhancement.
- [Effects of Shenmai injection on immune function in stomach cancer patients after chemotherapy]
PubMed ID: 8580688
Shenmai injection (contains ginseng) increased T cell counts and NK/LAK activity post‑chemotherapy — immunomodulatory effects in clinical context but multi‑component and cancer setting.
- Efficacy and safety of the standardised Ginseng extract G115 for potentiating vaccination against the influenza syndrome and protection against the common cold [corrected]
PubMed ID: 8879982
Well‑powered RCT with G115 showed higher antibody titres, increased NK activity and fewer influenza/common cold cases — strong clinical and immunologic evidence for immune support.
- [Clinical observation on nasopharyngeal carcinoma treated with combined therapy of radiotherapy and ginseng polysaccharide injection]
PubMed ID: 12577414
Ginseng polysaccharide adjunct with radiotherapy increased NK/LAK activity and T‑lymphocyte levels — immune marker improvements.
- A placebo-controlled trial of a proprietary extract of North American ginseng (CVT-E002) to prevent acute respiratory illness in institutionalized older adults
PubMed ID: 14687309
CVT‑E002 (North American ginseng extract) strongly reduced laboratory‑confirmed influenza and RSV in institutionalized older adults in RCTs.
- Efficacy of an extract of North American ginseng containing poly-furanosyl-pyranosyl-saccharides for preventing upper respiratory tract infections: a randomized controlled trial
PubMed ID: 16247099
Large RCT showed modest reductions in number, severity and duration of colds over 4 months with North American ginseng extract.
- Efficacy of COLD-fX in the prevention of respiratory symptoms in community-dwelling adults: a randomized, double-blinded, placebo controlled trial
PubMed ID: 16566675
Daily North American ginseng reduced late‑season respiratory illness incidence and shortened symptom duration in seniors.
- Preventive effect of Korean red ginseng for acute respiratory illness: a randomized and double-blind clinical trial
PubMed ID: 23255845
Korean red ginseng reduced incidence of acute respiratory illness in healthy adults over 12 weeks (RCT).
- A 14-week randomized, placebo-controlled, double-blind clinical trial to evaluate the efficacy and safety of ginseng polysaccharide (Y-75)
PubMed ID: 25297058
Randomized double‑blind trial of ginseng polysaccharide Y‑75 showed robust increases in NK cell activity, phagocytosis and TNF‑α over 8–14 weeks in healthy volunteers.
- Effect of ginseng polysaccharides and dendritic cells on the balance of Th1/Th2 T helper cells in patients with non-small cell lung cancer
PubMed ID: 25618966
NSCLC patients given DCs plus ginseng polysaccharides showed increased Th1 cytokines and Th1/Th2 ratios, indicating immune skewing (confounded by combined therapy).
- [A multicenter, large-sample, randomized clinical trial on improving the median survival time of advanced non-small cell lung cancer by combination of Ginseng Rg3 and chemotherapy]
PubMed ID: 29730918
Ginseng Rg3 reduced chemotherapy‑related myelosuppression (Hb/WBC declines) → supports hematologic/immune protection in oncology adjunct.
- Korean Red Ginseng Potentially Improves Maintaining Antibodies after COVID-19 Vaccination: A 24-Week Longitudinal Study
PubMed ID: 37049424
Continuous Korean Red Ginseng use was associated with a more sustained neutralizing antibody response after COVID‑19 vaccination (large longitudinal study).
- [Effects of Yiqi Huoxue Jiedu formula on the gut microbiota in elderly patients with pulmonary-derived sepsis based on 16S rDNA sequencing: a multicenter prospective randomized double-blind controlled trial]
PubMed ID: 40819941
Yiqi Huoxue Jiedu formula (includes Panax) lowered procalcitonin and improved clinical scores in sepsis patients, implying immunomodulation.
Mental clarity (15)
- Single doses of Panax ginseng (G115) reduce blood glucose levels and improve cognitive performance during sustained mental activity
PubMed ID: 15982990
Acute improvements in mental arithmetic and reduced subjective mental fatigue consistent with enhanced mental clarity after single dose.
- Effect of Memo®, a natural formula combination, on Mini-Mental State Examination scores in patients with mild cognitive impairment
PubMed ID: 23950642
MCI trial showed rapid MMSE gains with Ginkgo+Panax+royal jelly—clinically meaningful boost in cognition/clarity (combination).
- The memory enhancing effects of a Ginkgo biloba/Panax ginseng combination in healthy middle-aged volunteers
PubMed ID: 11140327
Ginkgo+Panax combo improved composite memory quality and cognitive function—translates to improved mental clarity (combination evidence).
- A randomized, placebo-controlled trial investigating the acute and chronic benefits of American Ginseng (Cereboost®) on mood and cognition in healthy young adults, including in vitro investigation of gut microbiota changes as a possible mechanism of action
PubMed ID: 34396468
Strong acute and short‑term improvements in attention accuracy and reaction time imply enhanced mental clarity with American ginseng.
- Antifatigue effects of Panax ginseng C.A. Meyer: a randomised, double-blind, placebo-controlled trial
PubMed ID: 23613825
Reductions in mental fatigue and oxidative stress in chronic fatigue patients are consistent with better mental clarity.
- Effects of Korean red ginseng extract on behavior in children with symptoms of inattention and hyperactivity/impulsivity: a double-blind randomized placebo-controlled trial
PubMed ID: 25369174
Improved attention scores and QEEG changes with Korean red ginseng support clearer cognitive processing in ADHD‑like children.
- Effect of Hydroponically Grown Red Panax Ginseng on Perceived Stress Level, Emotional Processing, and Cognitive Functions in Moderately Stressed Adults: A Randomized, Double-Blind, Placebo-Controlled Study
PubMed ID: 40289951
Improvements in cognitive processing latency indicate enhanced mental clarity in moderately stressed adults after short‑term ginseng.
- Efficacy and Safety of Panax ginseng Sprout Extract in Subjective Memory Impairment: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial
PubMed ID: 38931306
Global cognition (MoCA‑K) and memory improvements in older adults support clearer mental function.
- Acute effects of combined Bacopa, American ginseng and whole coffee fruit on working memory and cerebral haemodynamic response of the prefrontal cortex: a double-blind, placebo-controlled study
PubMed ID: 31736428
Improved N‑back accuracy and PFC hemodynamics after multi‑ingredient (contains ginseng) suggest better mental clarity acutely.
- Improved working memory performance following administration of a single dose of American ginseng (Panax quinquefolius L.) to healthy middle-age adults
PubMed ID: 25778987
Acute working memory improvements with American ginseng imply enhanced mental clarity/processing at 3 h.
- HT1001, a proprietary North American ginseng extract, improves working memory in schizophrenia: a double-blind, placebo-controlled study
PubMed ID: 22213250
Working memory improvements imply enhanced mental clarity/processing in treated patients.
- Panax ginseng (G115) improves aspects of working memory performance and subjective ratings of calmness in healthy young adults
PubMed ID: 20737519
Working memory and arithmetic improvements with G115 support clearer mental processing.
- Effects of American ginseng (Panax quinquefolius) on neurocognitive function: an acute, randomised, double-blind, placebo-controlled, crossover study
PubMed ID: 20676609
Consistent acute improvements in attention, working memory and reaction‑time accuracy indicate improved mental clarity.
- An open-label trial of Korean red ginseng as an adjuvant treatment for cognitive impairment in patients with Alzheimer's disease
PubMed ID: 18684311
Dose‑dependent cognitive/functional benefits in dementia imply clearer cognition at higher doses.
- Panax ginseng enhances cognitive performance in Alzheimer disease
PubMed ID: 18580589
Short‑term cognitive improvements in AD patients suggest some restoration of clarity while treated.
Memory (15)
- [Clinical study on a randomized, double-blind control of Shenwu gelatin capsule in treatment of mild cognitive impairment]
PubMed ID: 17993008
Compound medicine including ginseng improved memory quotient in mild cognitive impairment, comparable to aniracetam (multi‑ingredient trial).
- Panax ginseng enhances cognitive performance in Alzheimer disease
PubMed ID: 18580589
Open randomized study in AD patients found MMSE and ADAS improvements while on Panax ginseng (reversed after stopping) — strong memory‑related signal.
- Effect of Memo®, a natural formula combination, on Mini-Mental State Examination scores in patients with mild cognitive impairment
PubMed ID: 23950642
MCI trial: Ginkgo+Panax+royal jelly produced ~+2 MMSE points vs placebo in 4 weeks—clinically meaningful cognitive improvement (combination formula).
- The memory enhancing effects of a Ginkgo biloba/Panax ginseng combination in healthy middle-aged volunteers
PubMed ID: 11140327
Large RCT: Ginkgo+Panax combo produced ~7.5% improvement in composite memory quality sustained over 12 weeks (strong combo evidence).
- The cognitive, subjective, and physical effects of a ginkgo biloba/panax ginseng combination in healthy volunteers with neurasthenic complaints
PubMed ID: 9493479
Ginkgo+Panax dose‑related improvements on computerized cognitive tests over 90 days—combination evidence for memory.
- Neurocognitive effects a combined polyphenolic-rich herbal extract in healthy middle-aged adults - a randomised, double-blind, placebo-controlled study
PubMed ID: 38512715
28‑day mixed extract (includes Panax quinquefolius) significantly improved delayed recall and increased PFC activation.
- Efficacy and Safety of Panax ginseng Sprout Extract in Subjective Memory Impairment: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial
PubMed ID: 38931306
Panax ginseng sprout extract improved verbal and visual memory scores and reduced AChE in older adults with subjective memory complaints.
- Effects of Korean red ginseng on human gray matter volume and cognitive function: A voxel-based morphometry study
PubMed ID: 33217050
Randomized neuroimaging study reported parahippocampal GMV increases and modest cognitive test improvements including memory.
- Acute effects of combined Bacopa, American ginseng and whole coffee fruit on working memory and cerebral haemodynamic response of the prefrontal cortex: a double-blind, placebo-controlled study
PubMed ID: 31736428
Acute multi‑ingredient supplement containing American ginseng improved working memory and PFC activation → supports memory enhancement (component attribution partial).
- Improved working memory performance following administration of a single dose of American ginseng (Panax quinquefolius L.) to healthy middle-age adults
PubMed ID: 25778987
Single‑dose American ginseng improved working memory tasks at 3 h vs placebo → strong acute memory effect.
- Heat-processed ginseng enhances the cognitive function in patients with moderately severe Alzheimer's disease
PubMed ID: 22780999
Cognitive improvements (MMSE/ADAS) observed in Alzheimer's patients with heat-processed ginseng (pilot RCT).
- HT1001, a proprietary North American ginseng extract, improves working memory in schizophrenia: a double-blind, placebo-controlled study
PubMed ID: 22213250
Improved visual working memory in schizophrenia patients with North American ginseng (double-blind RCT).
- Panax ginseng (G115) improves aspects of working memory performance and subjective ratings of calmness in healthy young adults
PubMed ID: 20737519
G115 improved working memory/mental arithmetic after single and 7‑day dosing.
- Effects of American ginseng (Panax quinquefolius) on neurocognitive function: an acute, randomised, double-blind, placebo-controlled, crossover study
PubMed ID: 20676609
Acute standardized American ginseng improved immediate word recall and working memory speed in healthy young adults.
- An open-label trial of Korean red ginseng as an adjuvant treatment for cognitive impairment in patients with Alzheimer's disease
PubMed ID: 18684311
High‑dose Korean red ginseng improved ADAS and CDR scores in dementia patients over 12 weeks — supports memory/ cognitive benefit.
Sexual wellness (13)
- A new original nutraceutical formulation ameliorates the effect of Tadalafil on clinical score and cGMP accumulation
PubMed ID: 34286560
Multi-ingredient nutraceutical including ginseng added to tadalafil produced larger erectile-function gains; ginseng may have contributed to improved sexual function.
- Clinical efficacy of Korean red ginseng for erectile dysfunction
PubMed ID: 8750052
Randomized trial showed Korean red ginseng improved erectile function and satisfaction vs placebo — strong evidence for libido/sexual function benefit.
- A double-blind crossover study evaluating the efficacy of korean red ginseng in patients with erectile dysfunction: a preliminary report
PubMed ID: 12394711
Korean red ginseng RCT showed significant improvements in IIEF and objective rigidity measures — strong evidence for sexual function benefit.
- Study of the efficacy of Korean Red Ginseng in the treatment of erectile dysfunction
PubMed ID: 16855773
Korean red ginseng modestly improved self‑reported erectile function (IIEF‑5) in men with mild–moderate ED (double‑blind RCT).
- Effects of tissue-cultured mountain ginseng (Panax ginseng CA Meyer) extract on male patients with erectile dysfunction
PubMed ID: 19234482
Randomized double‑blind trial showed significant improvements in IIEF domains and overall sexual satisfaction after tissue‑cultured Panax ginseng.
- Effects of Korean red ginseng on sexual arousal in menopausal women: placebo-controlled, double-blind crossover clinical study
PubMed ID: 20141583
Korean red ginseng modestly improved sexual arousal domain and global assessment in menopausal women.
- Effects of Korean ginseng berry extract on sexual function in men with erectile dysfunction: a multicenter, placebo-controlled, double-blind clinical study
PubMed ID: 23254461
Korean ginseng berry extract improved erectile function (IIEF) and premature ejaculation scores in men (multicenter RCT).
- Effects of ginseng on peripheral blood mitochondrial DNA copy number and hormones in men with metabolic syndrome: A randomized clinical and pilot study
PubMed ID: 26860800
Red ginseng raised total testosterone in men with metabolic syndrome over 4 weeks—biologically plausible to enhance libido.
- Effects of Korean red ginseng on semen parameters in male infertility patients: A randomized, placebo-controlled, double-blind clinical study
PubMed ID: 25967606
12‑week RCT showed improvements in sperm concentration, motility and morphology—supports male reproductive health and potential libido/sexual function benefits.
- The effect of ginseng on sexual dysfunction in menopausal women: A double-blind, randomized, controlled trial
PubMed ID: 31331583
Panax ginseng RCT in postmenopausal women produced significant, clinically meaningful improvements in sexual function (FSFI) → strong evidence for libido/sexual function.
- Ginseng treatment improves the sexual side effects of methadone maintenance treatment
PubMed ID: 31082749
Ginseng supplementation reduced methadone‑associated sexual dysfunction vs placebo → moderate evidence for sexual function improvement.
- Vitamin E and ginseng supplementation to enhance female sexual function: a randomized, double-blind, placebo-controlled, clinical trial
PubMed ID: 32893745
Vitamin E + ginseng improved sexual desire and satisfaction domains (FSFI) though total sexual function unchanged — moderate evidence for libido.
- Semen quality in patients with Chlamydia trachomatis genital infection treated concurrently with prulifloxacin and a phytotherapeutic agent
PubMed ID: 21979301
Multi‑ingredient supplement including ginseng produced large, clinically meaningful improvements in sperm concentration/motility in men with infection‑related semen problems (sexual function proxy).
Focus & concentration (13)
- Panax ginseng (G115) improves aspects of working memory performance and subjective ratings of calmness in healthy young adults
PubMed ID: 20737519
Single and 7-day G115 dosing improved working memory measures and calmness — supports better focused cognition.
- Effect of Hydroponically Grown Red Panax Ginseng on Perceived Stress Level, Emotional Processing, and Cognitive Functions in Moderately Stressed Adults: A Randomized, Double-Blind, Placebo-Controlled Study
PubMed ID: 40289951
Hydroponic red ginseng improved cognitive planning latency and some processing measures vs placebo in stressed adults.
- Efficacy and Safety of Panax ginseng Sprout Extract in Subjective Memory Impairment: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial
PubMed ID: 38931306
Panax ginseng sprout extract improved verbal/visual memory and global cognition in older adults, which supports better focus.
- Acute effects of combined Bacopa, American ginseng and whole coffee fruit on working memory and cerebral haemodynamic response of the prefrontal cortex: a double-blind, placebo-controlled study
PubMed ID: 31736428
Multi‑ingredient supplement including American ginseng acutely improved working memory and PFC hemodynamics → supports focus (attribution partial).
- Improved working memory performance following administration of a single dose of American ginseng (Panax quinquefolius L.) to healthy middle-age adults
PubMed ID: 25778987
Single‑dose American ginseng improved working memory at 3 h in healthy middle‑aged adults → acute focus/cognitive attention benefit.
- Heat-processed ginseng enhances the cognitive function in patients with moderately severe Alzheimer's disease
PubMed ID: 22780999
Heat-processed ginseng produced cognitive test improvements in Alzheimer's patients (pilot RCT).
- HT1001, a proprietary North American ginseng extract, improves working memory in schizophrenia: a double-blind, placebo-controlled study
PubMed ID: 22213250
North American ginseng improved visual working memory in schizophrenia patients (double-blind RCT).
- Effects of American ginseng (Panax quinquefolius) on neurocognitive function: an acute, randomised, double-blind, placebo-controlled, crossover study
PubMed ID: 20676609
Standardized American ginseng acutely improved attention, working memory speed and recall in healthy adults.
- An open-label trial of Korean red ginseng as an adjuvant treatment for cognitive impairment in patients with Alzheimer's disease
PubMed ID: 18684311
High‑dose Korean red ginseng improved ADAS/CDR in dementia as adjuvant — implies cognitive/attentional benefit at higher doses.
- Single doses of Panax ginseng (G115) reduce blood glucose levels and improve cognitive performance during sustained mental activity
PubMed ID: 15982990
Single‑dose Panax ginseng improved mental arithmetic performance (serial sevens) and reduced subjective mental fatigue acutely.
- Efficacy of Omega-3 and Korean Red Ginseng in Children with Subthreshold ADHD: A Double-Blind, Randomized, Placebo-Controlled Trial
PubMed ID: 32847461
Omega‑3 + Korean red ginseng trial in children with subthreshold ADHD improved attention/ADHD ratings (combo product).
- Effects of Korean red ginseng extract on behavior in children with symptoms of inattention and hyperactivity/impulsivity: a double-blind randomized placebo-controlled trial
PubMed ID: 25369174
Korean red ginseng RCT in children improved inattention scores and QEEG indices—strong direct signal for focus.
- A randomized, placebo-controlled trial investigating the acute and chronic benefits of American Ginseng (Cereboost®) on mood and cognition in healthy young adults, including in vitro investigation of gut microbiota changes as a possible mechanism of action
PubMed ID: 34396468
Randomized trial of American ginseng showed robust improvements in attention accuracy and faster reaction time (acute and acute‑on‑chronic).
Metabolism (10)
- Diabetes-ameliorating effects of fermented red ginseng and causal effects on hormonal interactions: testing the hypothesis by multiple group path analysis
PubMed ID: 23675990
Fermented red ginseng in postmenopausal women produced modest but significant improvements in HbA1c, insulin and HOMA‑IR—direct metabolic benefit.
- Co-administration of a konjac-based fibre blend and American ginseng (Panax quinquefolius L.) on glycaemic control and serum lipids in type 2 diabetes: a randomized controlled, cross-over clinical trial
PubMed ID: 28687934
Konjac fiber + American ginseng lowered HbA1c and improved lipid profile over 12 weeks—meaningful metabolic improvements (combination).
- [Effect of panax quinquefolius saponin on insulin sensitivity in patients of coronary heart disease with blood glucose abnormality]
PubMed ID: 18198636
American ginseng saponin adjunct improved beta‑cell function and lowered cholesterol in CHD patients with glucose abnormalities — metabolic/endocrine improvements.
- [Effect of renshen jianxin capsule for alleviating insulin resistance in patients with coronary heart disease and glucose tolerance impairment]
PubMed ID: 19960983
Ginseng‑containing capsule improved insulin sensitivity in CHD patients with impaired glucose tolerance over 20 weeks.
- Supplementation of cheonggukjang and red ginseng cheonggukjang can improve plasma lipid profile and fasting blood glucose concentration in subjects with impaired fasting glucose
PubMed ID: 21128827
Red‑ginseng cheonggukjang lowered total and LDL cholesterol and fasting glucose in impaired fasting glucose subjects — strong metabolic benefit.
- Postprandial glucose-lowering effects of fermented red ginseng in subjects with impaired fasting glucose or type 2 diabetes: a randomized, double-blind, placebo-controlled clinical trial
PubMed ID: 25015735
Randomized double‑blind trial of fermented red ginseng reduced postprandial glucose and glucose AUC and increased 2‑h insulin in impaired fasting glucose/T2D subjects.
- Effects of ginseng berry saponins from panax ginseng on glucose metabolism of patients with prediabetes: A randomized, double-blinded, placebo-controlled, crossover trial
PubMed ID: 39004031
Ginseng berry saponin significantly reduced 2‑h postprandial glucose, improved HOMA‑IR and increased HDL in prediabetic individuals (well‑powered trial).
- Efficacy and safety of red ginseng extract powder (KGC05pg) in achieving glycemic control in prediabetic Korean adults: A 12-week, single-center, randomized, double-blind, parallel-group, placebo-controlled study
PubMed ID: 39969290
Korean red ginseng improved fasting and postload glucose and HOMA‑IR in prediabetic adults in an RCT.
- Short-Term Panax Ginseng Extract Supplementation Reduces Fasting Blood Triacylglycerides and Oxygen Consumption during Sub-Maximal Aerobic Exercise in Male Recreational Athletes
PubMed ID: 38785940
Short‑term Panax lowered fasting triglycerides, a favorable metabolic effect.
- Co-administration of viscous fiber, Salba-chia and ginseng on glycemic management in type 2 diabetes: a double-blind randomized controlled trial
PubMed ID: 33486572
24‑week combination including American + Korean red ginseng modestly improved HbA1c (−0.27% overall; −0.56% in higher baseline HbA1c subgroup).
Alertness (9)
- Acute effects of combined Bacopa, American ginseng and whole coffee fruit on working memory and cerebral haemodynamic response of the prefrontal cortex: a double-blind, placebo-controlled study
PubMed ID: 31736428
Improved N‑back performance and increased PFC activation after multi‑ingredient including ginseng support alertness gains.
- Improved working memory performance following administration of a single dose of American ginseng (Panax quinquefolius L.) to healthy middle-age adults
PubMed ID: 25778987
Acute working memory gains at 3 h imply improved alertness/concentration after American ginseng.
- Panax ginseng (G115) improves aspects of working memory performance and subjective ratings of calmness in healthy young adults
PubMed ID: 20737519
Working memory and arithmetic performance gains imply better alertness after dosing.
- Effects of American ginseng (Panax quinquefolius) on neurocognitive function: an acute, randomised, double-blind, placebo-controlled, crossover study
PubMed ID: 20676609
Improvements in choice reaction time accuracy and working memory speed indicate heightened alertness acutely.
- A randomized, placebo-controlled trial investigating the acute and chronic benefits of American Ginseng (Cereboost®) on mood and cognition in healthy young adults, including in vitro investigation of gut microbiota changes as a possible mechanism of action
PubMed ID: 34396468
American ginseng produced faster reaction times and improved attention accuracy—direct evidence for better alertness.
- Single doses of Panax ginseng (G115) reduce blood glucose levels and improve cognitive performance during sustained mental activity
PubMed ID: 15982990
Single‑dose study reported improved cognitive performance and reduced mental fatigue consistent with better alertness.
- Effects of Korean red ginseng extract on behavior in children with symptoms of inattention and hyperactivity/impulsivity: a double-blind randomized placebo-controlled trial
PubMed ID: 25369174
QEEG improvements and inattention score reductions in Korean red ginseng trial indicate improved alertness/attentional arousal.
- Efficacy of Omega-3 and Korean Red Ginseng in Children with Subthreshold ADHD: A Double-Blind, Randomized, Placebo-Controlled Trial
PubMed ID: 32847461
Omega‑3 + Korean red ginseng in children improved ADHD symptoms including alertness/attention (combination product).
- Effect of Hydroponically Grown Red Panax Ginseng on Perceived Stress Level, Emotional Processing, and Cognitive Functions in Moderately Stressed Adults: A Randomized, Double-Blind, Placebo-Controlled Study
PubMed ID: 40289951
Cognitive processing latency (planning) improved, consistent with better alertness/processing speed.
Mood balance (6)
- Effect of Red Ginseng on Genotoxicity and Health-Related Quality of Life after Adjuvant Chemotherapy in Patients with Epithelial Ovarian Cancer: A Randomized, Double Blind, Placebo-Controlled Trial
PubMed ID: 28753932
Red ginseng improved emotional QoL subscales after chemotherapy, indicating mood benefits in that population.
- Neurocognitive effects a combined polyphenolic-rich herbal extract in healthy middle-aged adults - a randomised, double-blind, placebo-controlled study
PubMed ID: 38512715
Multi‑ingredient supplement including Panax improved positive affect and PFC activation versus placebo in middle‑aged adults.
- Effects of sun ginseng on subjective quality of life in cancer patients: a double-blind, placebo-controlled pilot trial
PubMed ID: 16882101
Sun ginseng improved psychological WHOQOL and GHQ‑12 scores in cancer patients, indicating mood/psychological well‑being benefit.
- Korean red ginseng for cancer-related fatigue in colorectal cancer patients with chemotherapy: A randomised phase III trial
PubMed ID: 32172198
Trial showed significant improvement in the 'Mood' fatigue-related domain during chemotherapy with Korean red ginseng.
- Effects of Panax Ginseng on Health-Related Quality of Life in Patients with Non-Metastatic Breast Cancer: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial Ginseng for HRQOL in Breast Cancer
PubMed ID: 37218691
Emotional well‑being was preserved/improved in chemotherapy patients taking ginseng versus placebo.
- Effect of Hydroponically Grown Red Panax Ginseng on Perceived Stress Level, Emotional Processing, and Cognitive Functions in Moderately Stressed Adults: A Randomized, Double-Blind, Placebo-Controlled Study
PubMed ID: 40289951
Hydroponic red ginseng significantly reduced perceived stress and negative affect vs placebo in moderately stressed adults.
Endurance (4)
- A randomized, double-blind, multicenter, placebo-controlled clinical study on the efficacy and safety of Shenmai injection in patients with chronic heart failure
PubMed ID: 27045864
6MWD improvement in CHF patients indicates better functional endurance (SMI contains ginseng).
- Short-Term Panax Ginseng Extract Supplementation Reduces Fasting Blood Triacylglycerides and Oxygen Consumption during Sub-Maximal Aerobic Exercise in Male Recreational Athletes
PubMed ID: 38785940
Decreased oxygen consumption during submaximal aerobic exercise implies improved endurance capacity or efficiency.
- Ginseng Berry Concentrate Alleviates Fatigue in Humans: A Randomized, Placebo-Controlled, Double-Blinded Clinical Trial
PubMed ID: 41022533
Lower resting lactic acid and reduced fatigue may help sustain longer activity, supporting endurance.
- Ginseng improves pulmonary functions and exercise capacity in patients with COPD
PubMed ID: 12814035
Marked improvements in VO2max and exercise capacity in COPD patients indicate better endurance.
Workout performance (4)
- Ginseng improves pulmonary functions and exercise capacity in patients with COPD
PubMed ID: 12814035
Randomized trial in COPD showed large, clinically meaningful improvements in FVC, FEV1 and VO2max (clear exercise capacity gains).
- A randomized, double-blind, multicenter, placebo-controlled clinical study on the efficacy and safety of Shenmai injection in patients with chronic heart failure
PubMed ID: 27045864
Shenmai injection (contains ginseng) improved 6‑minute walk distance in CHF patients → moderate evidence of functional/ exercise performance gain (multi‑herb injection).
- Short-Term Panax Ginseng Extract Supplementation Reduces Fasting Blood Triacylglycerides and Oxygen Consumption during Sub-Maximal Aerobic Exercise in Male Recreational Athletes
PubMed ID: 38785940
Panax reduced VO2 during submaximal aerobic exercise and decreased energy cost in recreational male athletes.
- Ginseng Berry Concentrate Alleviates Fatigue in Humans: A Randomized, Placebo-Controlled, Double-Blinded Clinical Trial
PubMed ID: 41022533
Ginseng berry lowered resting lactic acid and reduced fatigue scores, which may support exercise performance.
Vitality (4)
- Effect of Hydroponically Grown Red Panax Ginseng on Perceived Stress Level, Emotional Processing, and Cognitive Functions in Moderately Stressed Adults: A Randomized, Double-Blind, Placebo-Controlled Study
PubMed ID: 40289951
Reduced perceived stress and negative affect plus cognitive improvements can increase subjective vitality over short term.
- The Effects of Korean Red Ginseng on Biological Aging and Antioxidant Capacity in Postmenopausal Women: A Double-Blind Randomized Controlled Study
PubMed ID: 34578969
Fatigue reduction and mitochondrial improvements in postmenopausal women indicate increased vitality.
- Effects of tissue-cultured mountain ginseng (Panax ginseng CA Meyer) extract on male patients with erectile dysfunction
PubMed ID: 19234482
Improved erectile function and satisfaction typically correlate with higher subjective vitality.
- Ginseng Berry Concentrate Alleviates Fatigue in Humans: A Randomized, Placebo-Controlled, Double-Blinded Clinical Trial
PubMed ID: 41022533
Reductions in fatigue and lactic acid align with increased subjective and physiological vitality.
Stress & Anxiety (1)
- Effect of Hydroponically Grown Red Panax Ginseng on Perceived Stress Level, Emotional Processing, and Cognitive Functions in Moderately Stressed Adults: A Randomized, Double-Blind, Placebo-Controlled Study
PubMed ID: 40289951
Hydroponic red ginseng significantly reduced perceived stress (PSS) and negative affect over 3 weeks in moderately stressed adults.
Sleep quality (1)
- Phyto-Female Complex for the relief of hot flushes, night sweats and quality of sleep: randomized, controlled, double-blind pilot study
PubMed ID: 17454163
Multi‑herb formula containing American ginseng markedly improved sleep quality in menopausal women.
Similar by evidence
Supplements the same benefits carry qualifying findings for — a fact about the evidence graph, not a recommendation to swap.
Products with Panax Ginseng
Search all371 products whose verified label declares Panax Ginseng — not every bottle that mentions it in a title.
Being studied right now
Recruiting clinical trials registered on ClinicalTrials.gov. A trial in progress has no result yet — this is what the field is asking, not what it found.