Lupin
12 benefits mapped to clinical evidence across supplements.
Dose per serving from research
8 study groups in 7 studies say how much Lupin participants took a day.
These are the doses the studies gave. They are not a recommendation.
Most common: 10 g to 25 g, 75% of 8 study groups.
| Daily dose | Study groups |
|---|---|
| 10 g to 25 g | 6 |
| 25 g to 50 g | 2 |
Benefit Evidence
Research sources
Metabolism (7)
- Personalized nutrition in type 2 diabetes remission: application of digital twin technology for predictive glycemic control
PubMed ID: 39634180
Digital‑twin personalized nutrition produced large HbA1c reductions and weight loss — directly relevant to metabolic improvement.
- Consuming a mixed diet enriched with lupin protein beneficially affects plasma lipids in hypercholesterolemic subjects: a randomized controlled trial
PubMed ID: 24746974
Crossover RCT showed lupin protein lowered LDL and other cardiometabolic markers in hypercholesterolemic subjects.
- Hypocholesterolaemic effects of lupin protein and pea protein/fibre combinations in moderately hypercholesterolaemic individuals
PubMed ID: 22032303
Lupin protein reduced total and LDL cholesterol in an RCT—evidence for beneficial metabolic effects.
- The formation of short-chain fatty acids is positively associated with the blood lipid-lowering effect of lupin kernel fiber in moderately hypercholesterolemic adults
PubMed ID: 24572041
Lupin kernel fiber lowered total, LDL cholesterol and triglycerides in a controlled trial—supports metabolic benefit.
- Lupin protein compared to casein lowers the LDL cholesterol:HDL cholesterol-ratio of hypercholesterolemic adults
PubMed ID: 19680704
Replacing protein with lupin protein modestly lowered LDL and improved LDL:HDL ratio in hypercholesterolemic adults (metabolic/cardio risk marker).
- Effects of lupin-enriched foods on body composition and cardiovascular disease risk factors: a 12-month randomized controlled weight loss trial
PubMed ID: 20938438
12‑month lupin‑enriched foods improved fasting insulin and HOMA (insulin sensitivity) despite no weight change.
- Lupin protein positively affects plasma LDL cholesterol and LDL:HDL cholesterol ratio in hypercholesterolemic adults after four weeks of supplementation: a randomized, controlled crossover study
PubMed ID: 23902673
Randomized human trial: 25 g/day lupin protein lowered LDL and systolic BP — favorable metabolic/cardiovascular markers.
Protein source (6)
- Effects of legume kernel fibres and citrus fibre on putative risk factors for colorectal cancer: a randomised, double-blind, crossover human intervention trial
PubMed ID: 24060277
Lupin kernel fibre trial shows significant fiber and colonic metabolite benefits—contributes to plant‑based nutritional value.
- Consuming a mixed diet enriched with lupin protein beneficially affects plasma lipids in hypercholesterolemic subjects: a randomized controlled trial
PubMed ID: 24746974
25 g/day lupin protein in a randomized crossover trial vs milk protein—supports lupin as a high‑quality plant protein.
- Hypocholesterolaemic effects of lupin protein and pea protein/fibre combinations in moderately hypercholesterolaemic individuals
PubMed ID: 22032303
Direct RCT using 25 g/day lupin protein (bars) demonstrating meaningful dietary replacement—strong evidence lupin is an effective plant protein source.
- Lupin protein positively affects plasma LDL cholesterol and LDL:HDL cholesterol ratio in hypercholesterolemic adults after four weeks of supplementation: a randomized, controlled crossover study
PubMed ID: 23902673
Human RCT with lupin protein isolate showing cardiometabolic benefits at dietary dosing — supports plant-based nutrition claims.
- Lupin protein compared to casein lowers the LDL cholesterol:HDL cholesterol-ratio of hypercholesterolemic adults
PubMed ID: 19680704
Lupin protein substituted for casein in RCT and produced metabolic benefits — supports use as plant protein.
- The formation of short-chain fatty acids is positively associated with the blood lipid-lowering effect of lupin kernel fiber in moderately hypercholesterolemic adults
PubMed ID: 24572041
Four‑week lupin kernel fiber RCT demonstrates plant‑derived fiber benefits on lipids and SCFA production.
Heart health (6)
- Consuming a mixed diet enriched with lupin protein beneficially affects plasma lipids in hypercholesterolemic subjects: a randomized controlled trial
PubMed ID: 24746974
Crossover RCT: lupin protein lowered LDL, homocysteine and other cardio‑metabolic markers in hypercholesterolemic subjects.
- Hypocholesterolaemic effects of lupin protein and pea protein/fibre combinations in moderately hypercholesterolaemic individuals
PubMed ID: 22032303
Randomized dietary trial showed lupin protein (25 g/day) significantly lowered total cholesterol and LDL—strong evidence for cardiovascular risk factor improvement.
- Lupin protein positively affects plasma LDL cholesterol and LDL:HDL cholesterol ratio in hypercholesterolemic adults after four weeks of supplementation: a randomized, controlled crossover study
PubMed ID: 23902673
Randomized human trial: lupin protein isolate (25 g/day) lowered LDL (notably in higher-baseline subgroup) and reduced systolic BP by ~8 mmHg — strong direct cardiometabolic benefit.
- Lupin kernel fibre-enriched foods beneficially modify serum lipids in men
PubMed ID: 15508014
One‑month lupin kernel fibre reduced total and LDL cholesterol in healthy men — cardio‑metabolic benefit.
- Lupin protein compared to casein lowers the LDL cholesterol:HDL cholesterol-ratio of hypercholesterolemic adults
PubMed ID: 19680704
Six‑week RCT: replacing protein with lupin protein modestly lowered LDL and improved LDL:HDL ratio in hypercholesterolemic adults.
- The formation of short-chain fatty acids is positively associated with the blood lipid-lowering effect of lupin kernel fiber in moderately hypercholesterolemic adults
PubMed ID: 24572041
Lupin kernel fiber reduced total, LDL cholesterol and triglycerides in a randomized, controlled crossover trial—robust lipid benefits.
Satiety (4)
- Effects of legume kernel fibres and citrus fibre on putative risk factors for colorectal cancer: a randomised, double-blind, crossover human intervention trial
PubMed ID: 24060277
Lupin fibre increases bulk and SCFA which are associated with satiety; fullness was not directly measured but is plausible.
- Hypocholesterolaemic effects of lupin protein and pea protein/fibre combinations in moderately hypercholesterolaemic individuals
PubMed ID: 22032303
Lupin protein (25 g/day) is likely to promote satiety relative to lower‑protein alternatives (indirect evidence from protein intervention).
- Lupin-enriched bread increases satiety and reduces energy intake acutely
PubMed ID: 17093146
Lupin‑enriched bread markedly increased subjective satiety and reduced subsequent intake in crossover trials.
- The formation of short-chain fatty acids is positively associated with the blood lipid-lowering effect of lupin kernel fiber in moderately hypercholesterolemic adults
PubMed ID: 24572041
Lupin fiber intervention increases SCFA and fiber intake—mechanistically consistent with prolonged fullness (indirect).
Bowel regularity (4)
- Effects of legume kernel fibres and citrus fibre on putative risk factors for colorectal cancer: a randomised, double-blind, crossover human intervention trial
PubMed ID: 24060277
Lupin kernel fibre trials increased stool bulk, sped transit and raised butyrate—direct high‑quality evidence lupin is an effective natural fiber source.
- The formation of short-chain fatty acids is positively associated with the blood lipid-lowering effect of lupin kernel fiber in moderately hypercholesterolemic adults
PubMed ID: 24572041
Four‑week RCT (25 g/d lupin kernel fiber) produced measurable physiological benefits (lipids, SCFA)—strong fiber evidence.
- Lupin kernel fibre foods improve bowel function and beneficially modify some putative faecal risk factors for colon cancer in men
PubMed ID: 16469156
Direct human evidence: lupin kernel fibre improved bowel habits and faecal biomarkers — strong evidence as a fiber source.
- Lupin kernel fibre-enriched foods beneficially modify serum lipids in men
PubMed ID: 15508014
One‑month lupin kernel fibre reduced cholesterol and improved lipid ratios — typical benefits of viscous/fermentable fibre.
Muscle maintenance (3)
- Hypocholesterolaemic effects of lupin protein and pea protein/fibre combinations in moderately hypercholesterolaemic individuals
PubMed ID: 22032303
Trial used substantial lupin protein (25 g/day) demonstrating that lupin is a significant plant protein source supportive of muscle maintenance.
- Consuming a mixed diet enriched with lupin protein beneficially affects plasma lipids in hypercholesterolemic subjects: a randomized controlled trial
PubMed ID: 24746974
Lupin protein intervention vs milk protein supports lupin as a protein source; relevant to preserving lean mass (indirect evidence).
- Switching treatment to cipaglucosidase alfa plus miglustat positively affects patient-reported outcome measures in patients with late-onset Pompe disease
PubMed ID: 39535661
Switching enzyme therapy in Pompe disease improved walk distance and breathing measures — directly relevant to muscle function/maintenance in a muscle disease context.
Digestive support (3)
- The formation of short-chain fatty acids is positively associated with the blood lipid-lowering effect of lupin kernel fiber in moderately hypercholesterolemic adults
PubMed ID: 24572041
Four‑week lupin kernel fiber lowered lipids and increased SCFA production; supports beneficial gut physiological effects.
- Effects of legume kernel fibres and citrus fibre on putative risk factors for colorectal cancer: a randomised, double-blind, crossover human intervention trial
PubMed ID: 24060277
Two‑week lupin kernel fibre RCT increased faecal weight, shortened transit time and raised butyrate—strong direct evidence for gut comfort/colon health.
- Lupin kernel fibre foods improve bowel function and beneficially modify some putative faecal risk factors for colon cancer in men
PubMed ID: 16469156
Randomized feeding (38 men): lupin kernel fibre improved defecation frequency, transit time and faecal butyrate — clear gut comfort effects.
Stomach comfort (3)
- Effects of legume kernel fibres and citrus fibre on putative risk factors for colorectal cancer: a randomised, double-blind, crossover human intervention trial
PubMed ID: 24060277
Lupin kernel fibre increased stool bulk and transit without reported adverse GI effects in the short trial—suggests tolerability, but evidence is limited.
- The formation of short-chain fatty acids is positively associated with the blood lipid-lowering effect of lupin kernel fiber in moderately hypercholesterolemic adults
PubMed ID: 24572041
Four‑week controlled trial reported physiological benefits with no notable tolerability signals—indirect support for being gentle in studied doses.
- Liking of health-functional foods containing lupin kernel fibre following repeated consumption in a dietary intervention setting
PubMed ID: 20542068
Repeated daily consumption of lupin‑fibre foods was well tolerated with no drop in overall liking — practical tolerability signal.
Weight management (2)
- Lupin-enriched bread increases satiety and reduces energy intake acutely
PubMed ID: 17093146
Acute reductions in subsequent energy intake after lupin‑enriched bread suggest potential to support weight control.
- Personalized nutrition in type 2 diabetes remission: application of digital twin technology for predictive glycemic control
PubMed ID: 39634180
Personalized nutrition intervention achieved marked weight loss — directly relevant to weight‑support benefits.
Nutrition source (2)
- Hypocholesterolaemic effects of lupin protein and pea protein/fibre combinations in moderately hypercholesterolaemic individuals
PubMed ID: 22032303
Lupin protein supplementation (25 g/day) provides substantial plant protein and improved serum lipids—supports the idea of a nutrient/protein boost.
- Consuming a mixed diet enriched with lupin protein beneficially affects plasma lipids in hypercholesterolemic subjects: a randomized controlled trial
PubMed ID: 24746974
Randomized crossover with lupin protein (25 g/day) demonstrates nutritional replacement effects vs milk protein.
Daily comfort (1)
- Personalized nutrition in type 2 diabetes remission: application of digital twin technology for predictive glycemic control
PubMed ID: 39634180
Sustained improvements in HbA1c, weight and liver fat indicate broad daily‑wellness benefits from a comprehensive nutrition program.
Appetite suppression (1)
- Lupin-enriched bread increases satiety and reduces energy intake acutely
PubMed ID: 17093146
Acute crossover trials: lupin‑enriched bread increased satiety, lowered subsequent intake and suppressed ghrelin vs white bread.
Similar by evidence
Supplements the same benefits carry qualifying findings for — a fact about the evidence graph, not a recommendation to swap.