Daily comfort

Pain/function ↓

NSAID need ↓

Pain/sleep: better, +11%

Spasticity: better, +45%

Sedation/AE: worse, 31%

Pain/function ↓ ~25-50%

Less NSAID use

Joint space preserved +0.3mm

Pain ↓; comfort ↑

Function ↑; daily ease ↑

Pain/function improvement

Biomarker shifts -31%

Strength/mobility +17%

Mass/weight gains

Hospital stay -4.3d

Pain/comfort up

+10% pain relief

Symptoms/function improved

Fatigue/recovery +31%

Physical function +15%

Cognition/sleep improved

Pain relief + function

Less discomfort/anxiety

Psychosis relief +19%

Mood/cognition gains -4.6

UTI relief, fewer recurrences

+88.6% cure; -60.8% recurrences

UTI fewer, comfort better

Pain/symptoms lower, -21% UTI

Pain relief & function

Respiratory/allergy relief

Similar symptom relief

Better than placebo

Filling/QoL: +50 pts

Exercise: +28 W, +1.8 min

HbA1c −2.9%, comfort ↑

Weight −7.4kg, comfort ↑

Fewer colds

Worse onset symptoms

Mood/anxiety/function +4.2

Post-stop worsening

Less pain, less stiffness

+pressure tolerance