Stomach comfort

Less stomach upset

Much fewer symptoms

Nausea/vomiting -20pp

Delayed CINV +QoL

Gastric emptying -51%

Reduced reflux pain

+17.0% less CKD

Faster stomach pH

Pain relief, +36%

Nausea reduction, -43%

Bloating/fullness relief

−95% drug absorption

Diarrhea reduced 28.9%

Diarrhea relief -42.5pp

Dyspepsia comfort NNT7

Less pain/bloating

GIS: significant drop

Crying −124 min

Reflux symptoms ↓44-51%

Dyspepsia improved

Stomachache -43%

Diarrhea relief +33/39

Less bloating/constipation

Shorter recovery -16.7%

Less pain; better QOL

+19-21% nausea control

Similar GERD relief

Bulk +33%

Transit -21%

Nausea, borborygmi +50g

Diarrhoea, loose stools 20-25g

Dyspepsia symptoms -81%

Gut balance -72%

Gut bacteria shifts

Bile-gene increase