Chromium
11 benefits mapped to clinical evidence across supplements.
Dose per serving from products
10,171 products in our catalogue print how much Chromium a serving holds.
Most common: 100 mcg to 250 mcg, 30% of 10,171 products.
| Dose per serving | Products |
|---|---|
| 1 mcg or less | 123 |
| 1 mcg to 2.5 mcg | 388 |
| 2.5 mcg to 5 mcg | 291 |
| 5 mcg to 10 mcg | 517 |
| 10 mcg to 25 mcg | 1,277 |
| 25 mcg to 50 mcg | 1,819 |
| 50 mcg to 100 mcg | 1,678 |
| 100 mcg to 250 mcg | 3,070 |
| 250 mcg to 500 mcg | 408 |
| 500 mcg to 1 mg | 237 |
| over 1 mg | 363 |
Dose per serving from research
64 study groups in 50 studies say how much Chromium participants took a day.
These are the doses the studies gave. They are not a recommendation.
Most common: 250 mcg to 500 mcg and 500 mcg to 1 mg, 28% of 64 study groups each.
| Daily dose | Study groups |
|---|---|
| 25 mcg or less | 4 |
| 25 mcg to 50 mcg | 2 |
| 50 mcg to 100 mcg | 1 |
| 100 mcg to 250 mcg | 14 |
| 250 mcg to 500 mcg | 18 |
| 500 mcg to 1 mg | 18 |
| 1 mg to 2.5 mg | 1 |
| 2.5 mg to 5 mg | 2 |
| 5 mg to 10 mg | 0 |
| 10 mg to 25 mg | 0 |
| 25 mg to 50 mg | 1 |
| over 50 mg | 3 |
Commonly used together
19 of 63 study groups took Chromium with something else. Shown: what 3 or more different studies gave.
What was given together, not what works together.
| Taken with | Study groups |
|---|---|
| Gymnema Sylvestre | 3 |
Benefit Evidence
Research sources
Cholesterol (39)
- Characterization of the metabolic and physiologic response to chromium supplementation in subjects with type 2 diabetes mellitus
PubMed ID: 20022616
Improved insulin sensitivity and glycemic markers (A1c in responders) are favorable blood biomarker changes with chromium picolinate.
- Safety and efficacy of oral DMSA therapy for children with autism spectrum disorders: Part A--medical results
PubMed ID: 19852789
DMSA chelation significantly increased urinary chromium loss, a clinically relevant effect on blood/body chromium status (implicates need to monitor markers).
- In patients with HIV-infection, chromium supplementation improves insulin resistance and other metabolic abnormalities: a randomized, double-blind, placebo controlled trial
PubMed ID: 20163347
Lowered triglycerides and improved HOMA‑IR indicate positive changes in common blood markers.
- Beneficial effect of chromium supplementation on glucose, HbA1C and lipid variables in individuals with newly onset type-2 diabetes
PubMed ID: 21570271
Reported reductions in LDL and modest TC/TG improvements in diabetics given chromium‑containing brewer's yeast.
- [Efficacy of tianmaixiaoke tablets in the treatment of newly diagnosed type 2 diabetes mellitus in China]
PubMed ID: 22944053
Chromium picolinate raised serum chromium and improved HbA1c/HOMA metrics in a subgroup — directly measured blood markers relevant to metabolic health.
- The effect of different bearing surfaces on metal ion levels in urine following 28 mm metal-on-metal and 28 mm metal-on-polyethylene total hip arthroplasty
PubMed ID: 23963035
Randomized trial showed very large (15x–26x) increases in urinary Cr/Co with metal‑on‑metal hips — strong evidence of implant-driven changes in metal blood/excretion markers.
- Metal hypersensitivity and metal ion levels in patients with coated or uncoated total knee arthroplasty: a randomised controlled study
PubMed ID: 23860793
Randomized knee implant trial measured plasma metal ions and found no elevation at 1 year — important safety/marker data.
- [Clinical assessment of dietary correction of metabolic syndrome by using specialized food product enriched with chrome]
PubMed ID: 24006749
Human metabolic‑syndrome trial reported a large LDL‑C reduction (−28.3%), directly supporting an effect on cholesterol in that study.
- Effects of supplemental nanoparticle trivalent chromium on the nutrient utilization, growth performance and serum traits of broilers
PubMed ID: 24947563
Nanoparticle chromium picolinate reduced LDL in broilers (direct lipid change in animals; human relevance uncertain).
- The Effects of Chromium Supplementation on Endocrine Profiles, Biomarkers of Inflammation, and Oxidative Stress in Women with Polycystic Ovary Syndrome: a Randomized, Double-Blind, Placebo-Controlled Trial
PubMed ID: 26613790
PCOS RCT showed reductions in hs‑CRP and MDA (improvements in inflammatory/oxidative blood markers).
- Chromium Supplementation and the Effects on Metabolic Status in Women with Polycystic Ovary Syndrome: A Randomized, Double-Blind, Placebo-Controlled Trial
PubMed ID: 26279073
PCOS RCT produced favorable changes in serum insulin and insulin‑sensitivity indices (blood biomarker improvements).
- Beneficial effects of oral chromium picolinate supplementation on glycemic control in patients with type 2 diabetes: A randomized clinical study
PubMed ID: 26302914
T2DM trial improved key blood markers (fasting/postprandial glucose, HbA1c).
- Controlling type-2 diabetes by inclusion of Cr-enriched yeast bread in the daily dietary pattern: a randomized clinical trial
PubMed ID: 27734127
Chromium‑enriched yeast RCT demonstrated improved HbA1c, fasting glucose and BP — direct improvements in clinically relevant blood markers.
- Effects of Supplemental Chromium Propionate on Serum Lipids, Carcass Traits, and Meat Quality of Heat-Stressed Broilers
PubMed ID: 27660074
Broiler study found dose‑dependent reductions in triglycerides and LDL‑C with chromium propionate, relevant to cholesterol/lipid health (animal data).
- A cross-sectional study measuring vanadium and chromium levels in paediatric patients with CKD
PubMed ID: 28592575
Study documented frequently elevated plasma chromium in children with CKD — directly relevant to systemic chromium blood measurements and marker interpretation.
- Comparison of metal ion concentrations and implant survival after total hip arthroplasty with metal-on-metal versus metal-on-polyethylene articulations
PubMed ID: 28699417
Long-term follow-up showed higher serum chromium with metal‑on‑metal hips — direct data on blood chromium levels.
- The Influences of Chromium Supplementation on Glycemic Control, Markers of Cardio-Metabolic Risk, and Oxidative Stress in Infertile Polycystic ovary Syndrome Women Candidate for In vitro Fertilization: a Randomized, Double-Blind, Placebo-Controlled Trial
PubMed ID: 29307112
PCOS RCT demonstrated improvements in fasting glucose, insulin resistance and triglycerides — these are clinically used blood markers of metabolic health.
- The short-term supplementation of monacolin K improves the lipid and metabolic patterns of hypertensive and hypercholesterolemic subjects at low cardiovascular risk
PubMed ID: 29951651
One‑month multi‑ingredient supplement (monacolin K + chromium) plus diet lowered total and LDL cholesterol more than diet alone; monacolin K is a likely major driver.
- Safety and Efficacy of NC120 for Improving Lipid Profile: A Double Blind Randomized Controlled Trial
PubMed ID: 31073102
28‑day RCT of a combination product (includes chromium) lowered TC and LDL vs placebo—relevant to cholesterol though confounded.
- The Influences of Chromium Supplementation on Metabolic Status in Patients with Type 2 Diabetes Mellitus and Coronary Heart Disease
PubMed ID: 31243685
Significant decreases in fasting glucose, insulin, HOMA‑IR and hs‑CRP in diabetics after chromium supplementation—meaningful blood marker changes.
- Improving the endothelial dysfunction in type 2 diabetes with chromium and vitamin D(3) byreducing homocysteine and oxidative stress: A randomized placebo-controlled trial
PubMed ID: 32971450
Randomized trial showed reductions in homocysteine, MDA and VCAM‑1 with chromium (±vit D) — direct improvement in blood biomarkers.
- A pilot study of the effects of chromium picolinate supplementation on serum fetuin-A, metabolic and inflammatory factors in patients with nonalcoholic fatty liver disease: A double-blind, placebo-controlled trial
PubMed ID: 33045675
Chromium picolinate lowered triglycerides, insulin, HOMA-IR and fetuin-A in NAFLD — direct improvements in several blood markers.
- Chromium picolinate balances the metabolic and clinical markers in nonalcoholic fatty liver disease: a randomized, double-blind, placebo-controlled trial
PubMed ID: 32804855
RCT showed improvements in adipokines and oxidative-stress blood markers (TAC, SOD, MDA) as well as weight/body-fat reductions.
- A comparative study to assess the use of chromium in type 2 diabetes mellitus
PubMed ID: 38024820
Direct RCT evidence: chromium supplementation produced large reductions in HbA1c and fasting glucose and favorable lipid changes.
- Efficacy and Tolerability of a Food Supplement Based on Zea mays L., Gymnema sylvestre (Retz.) R.br.ex Sm, Zinc and Chromium for the Maintenance of Normal Carbohydrate Metabolism: A Monocentric, Randomized, Double-Blind, Placebo-Controlled Clinical Trial
PubMed ID: 39125340
Multi‑ingredient supplement (includes chromium) lowered fasting glucose and modestly lowered HbA1c at higher dose; chromium contribution plausible but not isolated.
- The effect of chromium on inflammatory markers, 1st and 2nd phase insulin secretion in type 2 diabetes
PubMed ID: 23494740
Improved insulin sensitivity and reduced IL‑6 (inflammatory marker) in T2DM represent favorable changes in clinically relevant blood markers.
- Synchronizing positive effect of vitamin C and chromium on hyper lipidemia, hyperglycemia, liver enzymes and BMI of diabetes mellitus type 2 patients
PubMed ID: 38747270
Chromium+vitamin C was associated with improved HbA1c, LDL and liver enzymes in diabetics, showing broad blood‑marker improvements though not isolate chromium.
- Effects of niacin-bound chromium and grape seed proanthocyanidin extract on the lipid profile of hypercholesterolemic subjects: a pilot study
PubMed ID: 11508317
Niacin‑bound chromium produced ~10% total cholesterol and ~14% LDL declines; combination with grape seed extract produced larger (~16–20%) reductions.
- Chromium picolinate and biotin combination reduces atherogenic index of plasma in patients with type 2 diabetes mellitus: a placebo-controlled, double-blinded, randomized clinical trial
PubMed ID: 17496732
Chromium picolinate+biotin improved AIP, triglycerides and LDL/HDL ratio in obese T2D subjects.
- Combination of chromium and biotin improves coronary risk factors in hypercholesterolemic type 2 diabetes mellitus: a placebo-controlled, double-blind randomized clinical trial
PubMed ID: 17684468
Subgroup of hypercholesterolemic T2D patients showed LDL‑C and total cholesterol decreases with chromium picolinate+biotin.
- Effects of Chromium and Carnitine Co-supplementation on Body Weight and Metabolic Profiles in Overweight and Obese Women with Polycystic Ovary Syndrome: a Randomized, Double-Blind, Placebo-Controlled Trial
PubMed ID: 30977089
Multiple lipid and glycemic improvements reported in the PCOS RCT (chromium + carnitine) suggest benefits to several blood markers, though multi‑ingredient limits attribution.
- Effects of chromium supplementation on serum high-density lipoprotein cholesterol levels in men taking beta-blockers. A randomized, controlled trial
PubMed ID: 1683196
8‑week chromium supplementation increased HDL by ≈0.15 mmol/L in men on beta‑blockers—direct favorable effect on a cholesterol fraction.
- Elevated intakes of supplemental chromium improve glucose and insulin variables in individuals with type 2 diabetes
PubMed ID: 9356027
Demonstrated improvements in HbA1c, fasting/2‑hr glucose and reduced insulin in T2DM trial — strong support for positive changes in common blood markers.
- The effects of inorganic chromium and brewer's yeast supplementation on glucose tolerance, serum lipids and drug dosage in individuals with type 2 diabetes
PubMed ID: 11376359
Lower fasting/post-load glucose, fructosamine and triglycerides are direct improvements in blood markers.
- Effect of chromium supplementation on glucose tolerance and lipid profile
PubMed ID: 11533750
Improvements in glucose tolerance, fructosamine, triglycerides and HDL constitute positive changes in blood markers.
- Beneficial effects of chromium in people with type 2 diabetes, and urinary chromium response to glucose load as a possible indicator of status
PubMed ID: 11899964
Decreases in mean glucose and fructosamine in responders support blood marker improvements for some individuals.
- The influence of chromium chloride-containing milk to glycemic control of patients with type 2 diabetes mellitus: a randomized, double-blind, placebo-controlled trial
PubMed ID: 16784965
Chromium‑fortified milk produced clear improvements in FPG, fasting insulin and HbA1c in men with T2DM (strong blood marker evidence).
- Influence of chromium-enriched yeast on blood glucose and insulin variables, blood lipids, and markers of oxidative stress in subjects with type 2 diabetes mellitus
PubMed ID: 16632892
Chromium‑enriched yeast increased serum chromium and improved fasting glucose/insulin and oxidative stress markers — direct blood marker changes.
- Chromium picolinate supplementation attenuates body weight gain and increases insulin sensitivity in subjects with type 2 diabetes
PubMed ID: 16873787
Chromium picolinate improved insulin sensitivity and GHb and limited visceral fat gain — meaningful changes in clinical blood markers.
Metabolism (36)
- Chromium picolinate supplementation attenuates body weight gain and increases insulin sensitivity in subjects with type 2 diabetes
PubMed ID: 16873787
Improved insulin sensitivity and glycemic control plus attenuated visceral fat gain indicate broader metabolic improvements.
- Phenotype of subjects with type 2 diabetes mellitus may determine clinical response to chromium supplementation
PubMed ID: 17998017
In T2D, chromium picolinate increased the proportion of insulin-sensitivity responders, indicating a clinically relevant metabolic effect in a subgroup.
- Characterization of the metabolic and physiologic response to chromium supplementation in subjects with type 2 diabetes mellitus
PubMed ID: 20022616
RCT: meaningful metabolic improvements (insulin sensitivity, tissue lipids) in responder subgroup indicate overall metabolic benefit for some individuals.
- In patients with HIV-infection, chromium supplementation improves insulin resistance and other metabolic abnormalities: a randomized, double-blind, placebo controlled trial
PubMed ID: 20163347
Multiple metabolic improvements (HOMA‑IR, triglycerides, body fat) in insulin‑resistant patients support broader metabolic benefit.
- Beneficial effect of chromium supplementation on glucose, HbA1C and lipid variables in individuals with newly onset type-2 diabetes
PubMed ID: 21570271
Diabetics showed marked glycemic and some lipid improvements with chromium‑containing brewer's yeast (small, single‑blind study).
- Effect of chromium dinicocysteinate supplementation on circulating levels of insulin, TNF-α, oxidative stress, and insulin resistance in type 2 diabetic subjects: randomized, double-blind, placebo-controlled study
PubMed ID: 22674882
T2D randomized trial showed improvements in insulin, HOMA‑IR and TNF‑α—strongest human study in dataset supporting metabolic benefit.
- [Efficacy of tianmaixiaoke tablets in the treatment of newly diagnosed type 2 diabetes mellitus in China]
PubMed ID: 22944053
Human RCT: chromium picolinate significantly improved HbA1c and insulin metrics in low‑Cr T2D subgroup — strong evidence for metabolic benefit in selected patients.
- [Clinical assessment of dietary correction of metabolic syndrome by using specialized food product enriched with chrome]
PubMed ID: 24006749
Human trial in metabolic‑syndrome patients showed multiple beneficial metabolic outcomes (weight, BP, LDL), supporting improved overall metabolic profile in that cohort.
- Association of serum concentrations of magnesium and some trace elements with cardiometabolic risk factors and liver enzymes in adolescents: the CASPIAN-III Study
PubMed ID: 25422091
Cross‑sectional association between lower serum chromium and metabolic syndrome suggests a link to metabolic health (observational only).
- Chromium picolinate reduces insulin resistance in polycystic ovary syndrome: Randomized controlled trial
PubMed ID: 26663540
6‑month PCOS RCT lowered insulin and BMI and improved ovulation—multidimensional metabolic improvements.
- Chromium Supplementation and the Effects on Metabolic Status in Women with Polycystic Ovary Syndrome: A Randomized, Double-Blind, Placebo-Controlled Trial
PubMed ID: 26279073
PCOS RCT improved insulin sensitivity markers (important metabolic health indicators).
- Beneficial effects of oral chromium picolinate supplementation on glycemic control in patients with type 2 diabetes: A randomized clinical study
PubMed ID: 26302914
T2DM RCT with clinically meaningful improvements in glucose control and HbA1c (broad metabolic benefit).
- Controlling type-2 diabetes by inclusion of Cr-enriched yeast bread in the daily dietary pattern: a randomized clinical trial
PubMed ID: 27734127
Chromium‑enriched yeast RCT in T2D produced improvements in glycemia, weight and BP — strong evidence of broad metabolic benefit in that small trial.
- The Influences of Chromium Supplementation on Glycemic Control, Markers of Cardio-Metabolic Risk, and Oxidative Stress in Infertile Polycystic ovary Syndrome Women Candidate for In vitro Fertilization: a Randomized, Double-Blind, Placebo-Controlled Trial
PubMed ID: 29307112
Randomized chromium-only trial in PCOS improved multiple metabolic markers (glucose, insulin resistance, triglycerides) over 8 weeks.
- The Influences of Chromium Supplementation on Metabolic Status in Patients with Type 2 Diabetes Mellitus and Coronary Heart Disease
PubMed ID: 31243685
Multiple metabolic improvements in a randomized diabetic trial (glucose, insulin, HOMA‑IR, hs‑CRP) indicate broad metabolic benefit.
- Improving the endothelial dysfunction in type 2 diabetes with chromium and vitamin D(3) byreducing homocysteine and oxidative stress: A randomized placebo-controlled trial
PubMed ID: 32971450
Improvements in oxidative/inflammatory and endothelial markers (homocysteine, VCAM‑1, MDA) are consistent with systemic metabolic/vascular benefits.
- A pilot study of the effects of chromium picolinate supplementation on serum fetuin-A, metabolic and inflammatory factors in patients with nonalcoholic fatty liver disease: A double-blind, placebo-controlled trial
PubMed ID: 33045675
Multiple favorable changes (HOMA-IR, insulin, triglycerides, fetuin-A, QUICKI) in NAFLD patients indicate broad metabolic benefits from chromium picolinate in this small RCT.
- Chromium picolinate balances the metabolic and clinical markers in nonalcoholic fatty liver disease: a randomized, double-blind, placebo-controlled trial
PubMed ID: 32804855
Cr-picolinate produced weight/fat reductions, improved adipokines and antioxidant markers in NAFLD patients — meaningful multi-domain metabolic improvements.
- A comparative study to assess the use of chromium in type 2 diabetes mellitus
PubMed ID: 38024820
Substantial improvements in HbA1c, fasting glucose and some lipids indicate broad metabolic benefit in this small randomized chromium supplementation trial.
- Efficacy and Tolerability of a Food Supplement Based on Zea mays L., Gymnema sylvestre (Retz.) R.br.ex Sm, Zinc and Chromium for the Maintenance of Normal Carbohydrate Metabolism: A Monocentric, Randomized, Double-Blind, Placebo-Controlled Clinical Trial
PubMed ID: 39125340
Multi‑ingredient formulation (contains chromium) improved fasting glucose and HbA1c (higher dose); overall metabolic benefit plausible but cannot be attributed solely to chromium.
- The effects of chromium and vitamin D(3) co-supplementation on insulin resistance and tumor necrosis factor-alpha in type 2 diabetes: a randomized placebo-controlled trial
PubMed ID: 31593637
Prevention of worsening insulin resistance and reduced inflammatory marker in T2DM supports overall metabolic benefit.
- The effect of chromium on inflammatory markers, 1st and 2nd phase insulin secretion in type 2 diabetes
PubMed ID: 23494740
Strong human RCT evidence for improved insulin sensitivity and reduced IL‑6 in T2DM, supporting overall metabolic benefit.
- Synchronizing positive effect of vitamin C and chromium on hyper lipidemia, hyperglycemia, liver enzymes and BMI of diabetes mellitus type 2 patients
PubMed ID: 38747270
Chromium+vitamin C produced favorable changes in glycemic control, lipids and BMI in diabetics, indicating improved metabolic profile though chromium not isolated.
- Four-week supplementation with a natural dietary compound produces favorable changes in body composition
PubMed ID: 10345151
Multi‑ingredient supplement including chromium improved body composition during a dieting/exercise protocol, indicating beneficial metabolic effects in that context.
- [Assessment of efficiency of dietotherapy with addition of a vitamin-mineral complex in patients with diabetes mellitus type 2]
PubMed ID: 25300112
Vitamin‑mineral complex (contains chromium) produced larger blood glucose reductions versus diet alone in T2D women—supports metabolic improvement.
- The effect of chromium picolinate and biotin supplementation on glycemic control in poorly controlled patients with type 2 diabetes mellitus: a placebo-controlled, double-blinded, randomized trial
PubMed ID: 17109595
Chromium picolinate+biotin improved post‑load glucose exposure, fructosamine and triglycerides — relevant to overall metabolic profile.
- Combination of chromium and biotin improves coronary risk factors in hypercholesterolemic type 2 diabetes mellitus: a placebo-controlled, double-blind randomized clinical trial
PubMed ID: 17684468
Randomized trial showed modest glycemic and lipid improvements, supporting overall metabolic benefit in some patients.
- Chromium picolinate and biotin combination improves glucose metabolism in treated, uncontrolled overweight to obese patients with type 2 diabetes
PubMed ID: 17506119
Large RCT demonstrated clinically meaningful improvements in glycemic control—strong signal for metabolic health benefits from chromium picolinate+biotin adjunct therapy.
- Ascophyllum nodosum and Fucus vesiculosus on glycemic status and on endothelial damage markers in dysglicemic patients
PubMed ID: 30714233
Nutraceutical including chromium improved glycemic indices, HOMA‑IR and inflammatory markers in dysglycemic subjects (multi‑ingredient evidence).
- Effects of Chromium and Carnitine Co-supplementation on Body Weight and Metabolic Profiles in Overweight and Obese Women with Polycystic Ovary Syndrome: a Randomized, Double-Blind, Placebo-Controlled Trial
PubMed ID: 30977089
Multi‑endpoint metabolic improvements (weight, fasting glucose, insulin, HOMA‑IR, lipids) in an RCT support broader metabolic benefit, but chromium was combined with carnitine.
- Elevated intakes of supplemental chromium improve glucose and insulin variables in individuals with type 2 diabetes
PubMed ID: 9356027
Comprehensive metabolic improvements (HbA1c, glucose, insulin, cholesterol) in a sizable T2DM RCT support a meaningful effect on overall metabolic health in diabetics.
- The effects of inorganic chromium and brewer's yeast supplementation on glucose tolerance, serum lipids and drug dosage in individuals with type 2 diabetes
PubMed ID: 11376359
Consistent improvements in glucose, fructosamine and triglycerides in T2DM indicate broad metabolic benefit in that population.
- Effect of chromium supplementation on glucose tolerance and lipid profile
PubMed ID: 11533750
Multiple favorable shifts (glucose tolerance, fructosamine, TG/HDL) support overall metabolic improvements.
- Beneficial effects of chromium in people with type 2 diabetes, and urinary chromium response to glucose load as a possible indicator of status
PubMed ID: 11899964
Mean glycemic and some lipid improvements in responders show population-heterogeneous but meaningful metabolic effects.
- The influence of chromium chloride-containing milk to glycemic control of patients with type 2 diabetes mellitus: a randomized, double-blind, placebo-controlled trial
PubMed ID: 16784965
Strong randomized evidence of improved fasting glucose, fasting insulin and HbA1c in men with T2DM supports overall metabolic benefit.
- Influence of chromium-enriched yeast on blood glucose and insulin variables, blood lipids, and markers of oxidative stress in subjects with type 2 diabetes mellitus
PubMed ID: 16632892
Small RCT showing fasting glucose reduction and favorable insulin/oxidative stress marker changes supports metabolic benefit.
Blood sugar (35)
- Beneficial effect of chromium supplementation on glucose, HbA1C and lipid variables in individuals with newly onset type-2 diabetes
PubMed ID: 21570271
Small human trial with chromium‑containing brewer's yeast showed large reductions in fasting glucose and HbA1c.
- [Efficacy of tianmaixiaoke tablets in the treatment of newly diagnosed type 2 diabetes mellitus in China]
PubMed ID: 22944053
Randomized human study: chromium picolinate raised serum Cr and produced large HbA1c drops in low-baseline Cr patients — strong direct evidence for glycemic improvement in a subgroup.
- Effects of supplemental vitamin C and chromium on metabolic and hormonal responses, antioxidant status, and tonic immobility reactions of transported broiler chickens
PubMed ID: 24446191
Direct measures in broilers showed altered insulin and glucose/insulin ratio with chromium supplementation—clear relevance to carbohydrate metabolism (animal model).
- Chromium picolinate reduces insulin resistance in polycystic ovary syndrome: Randomized controlled trial
PubMed ID: 26663540
6‑month chromium picolinate RCT in PCOS lowered fasting insulin and BMI and improved ovulation (metabolic benefit).
- Chromium Supplementation and the Effects on Metabolic Status in Women with Polycystic Ovary Syndrome: A Randomized, Double-Blind, Placebo-Controlled Trial
PubMed ID: 26279073
Double‑blind RCT in PCOS: significant improvements in serum insulin, HOMA‑IR and QUICKI (insulin sensitivity markers).
- Chromium picolinate and biotin combination reduces atherogenic index of plasma in patients with type 2 diabetes mellitus: a placebo-controlled, double-blinded, randomized clinical trial
PubMed ID: 17496732
Chromium picolinate+biotin intervention improved atherogenic index/triglycerides in T2D which often accompanies glycemic improvements (supports glucose–lipid profile).
- Combination of chromium and biotin improves coronary risk factors in hypercholesterolemic type 2 diabetes mellitus: a placebo-controlled, double-blind randomized clinical trial
PubMed ID: 17684468
Large randomized trial showed modest reductions in HbA1c and fasting glucose with chromium picolinate+biotin.
- Chromium picolinate and biotin combination improves glucose metabolism in treated, uncontrolled overweight to obese patients with type 2 diabetes
PubMed ID: 17506119
Large RCT: chromium picolinate+biotin produced clinically meaningful HbA1c and fasting glucose reductions versus placebo.
- Ascophyllum nodosum and Fucus vesiculosus on glycemic status and on endothelial damage markers in dysglicemic patients
PubMed ID: 30714233
Nutraceutical including chromium picolinate improved HbA1c, fasting/postprandial glucose and HOMA‑IR in dysglycemic patients (multi‑ingredient).
- Effects of Chromium and Carnitine Co-supplementation on Body Weight and Metabolic Profiles in Overweight and Obese Women with Polycystic Ovary Syndrome: a Randomized, Double-Blind, Placebo-Controlled Trial
PubMed ID: 30977089
12‑week RCT in overweight PCOS showed improved fasting glucose, insulin and HOMA‑IR, but chromium was co‑administered with carnitine (confounder).
- A Dietary Supplement Containing Cinnamon, Chromium and Carnosine Decreases Fasting Plasma Glucose and Increases Lean Mass in Overweight or Obese Pre-Diabetic Subjects: A Randomized, Placebo-Controlled Trial
PubMed ID: 26406981
4‑month trial of cinnamon+chromium+carnosine in prediabetics produced a small but significant fasting glucose reduction and increased lean mass; multi‑ingredient limits specificity.
- Elevated intakes of supplemental chromium improve glucose and insulin variables in individuals with type 2 diabetes
PubMed ID: 9356027
Large RCT in type 2 diabetes showing significant improvements in HbA1c, fasting and 2‑hr glucose and reduced insulin — strong direct evidence of improved glycemic control.
- The effects of inorganic chromium and brewer's yeast supplementation on glucose tolerance, serum lipids and drug dosage in individuals with type 2 diabetes
PubMed ID: 11376359
Randomized cross-over in type 2 diabetes showed significant decreases in glucose and fructosamine with two chromium forms.
- Effect of chromium supplementation on glucose tolerance and lipid profile
PubMed ID: 11533750
Double-blind cross-over (200 µg/day CrCl3) improved glucose tolerance and fructosamine in free-living adults.
- Beneficial effects of chromium in people with type 2 diabetes, and urinary chromium response to glucose load as a possible indicator of status
PubMed ID: 11899964
Randomized crossover in NIDDM reported decreased mean glucose and fructosamine in responders after chromium supplementation.
- The influence of chromium chloride-containing milk to glycemic control of patients with type 2 diabetes mellitus: a randomized, double-blind, placebo-controlled trial
PubMed ID: 16784965
Randomized double-blind chromium‑fortified milk (400 µg/d) markedly lowered fasting glucose, fasting insulin and improved HbA1c in men with T2DM.
- Influence of chromium-enriched yeast on blood glucose and insulin variables, blood lipids, and markers of oxidative stress in subjects with type 2 diabetes mellitus
PubMed ID: 16632892
Chromium‑enriched yeast (400 µg/d) in small RCT reduced fasting glucose and improved insulin parameters in well‑controlled T2DM.
- Chromium picolinate supplementation attenuates body weight gain and increases insulin sensitivity in subjects with type 2 diabetes
PubMed ID: 16873787
Chromium picolinate (1000 µg) added to sulfonylurea improved insulin sensitivity and GHb (HbA1c) in T2DM.
- Phenotype of subjects with type 2 diabetes mellitus may determine clinical response to chromium supplementation
PubMed ID: 17998017
Randomized trial in type 2 diabetes: chromium picolinate increased insulin-sensitivity responder rate (63% vs 30%), indicating meaningful glycemic/insulin effects.
- Characterization of the metabolic and physiologic response to chromium supplementation in subjects with type 2 diabetes mellitus
PubMed ID: 20022616
Large RCT: chromium picolinate improved insulin sensitivity and glycemia in insulin‑resistant/poorer‑control responders.
- In patients with HIV-infection, chromium supplementation improves insulin resistance and other metabolic abnormalities: a randomized, double-blind, placebo controlled trial
PubMed ID: 20163347
RCT in insulin‑resistant HIV patients: chromium nicotinate improved insulin resistance (HOMA‑IR) and fasting insulin.
- Effect of chromium dinicocysteinate supplementation on circulating levels of insulin, TNF-α, oxidative stress, and insulin resistance in type 2 diabetic subjects: randomized, double-blind, placebo-controlled study
PubMed ID: 22674882
Randomized T2D trial: chromium dinicocysteinate produced significant decreases in insulin and HOMA‑IR, supporting glucose/insulin benefits.
- Efficacy and Tolerability of a Food Supplement Based on Zea mays L., Gymnema sylvestre (Retz.) R.br.ex Sm, Zinc and Chromium for the Maintenance of Normal Carbohydrate Metabolism: A Monocentric, Randomized, Double-Blind, Placebo-Controlled Clinical Trial
PubMed ID: 39125340
3‑month RCT of a multi‑ingredient supplement containing chromium reduced fasting glucose and (at higher dose) HbA1c, but chromium's isolated effect cannot be determined.
- A comparative study to assess the use of chromium in type 2 diabetes mellitus
PubMed ID: 38024820
Randomized trial of oral chromium (200 μg BID) in uncontrolled T2D produced large, clinically meaningful reductions in HbA1c and fasting glucose over 3 months.
- A pilot study of the effects of chromium picolinate supplementation on serum fetuin-A, metabolic and inflammatory factors in patients with nonalcoholic fatty liver disease: A double-blind, placebo-controlled trial
PubMed ID: 33045675
RCT of chromium picolinate in NAFLD showed significant improvements in HOMA-IR and insulin vs placebo — direct evidence of improved glycemic/insulin control.
- A novel nutritional supplement containing amino acids and chromium decreases postprandial glucose response in a randomized, double-blind, placebo-controlled study
PubMed ID: 32579549
Randomized crossover trial (Cr picolinate + amino acids) reduced postprandial glucose iAUC by ~24%—supports postprandial glucose control (chromium present though product included other actives).
- The Influences of Chromium Supplementation on Metabolic Status in Patients with Type 2 Diabetes Mellitus and Coronary Heart Disease
PubMed ID: 31243685
Randomized human trial (200 µg/day) in diabetics showed significant reductions in fasting glucose and HOMA‑IR—direct evidence for glycemic improvement.
- The effects of chromium and vitamin D(3) co-supplementation on insulin resistance and tumor necrosis factor-alpha in type 2 diabetes: a randomized placebo-controlled trial
PubMed ID: 31593637
Randomized trial in T2DM reported prevention of worsening insulin resistance with chromium (±vitamin D) vs control—supports insulin/glycemic benefit.
- The Influences of Chromium Supplementation on Glycemic Control, Markers of Cardio-Metabolic Risk, and Oxidative Stress in Infertile Polycystic ovary Syndrome Women Candidate for In vitro Fertilization: a Randomized, Double-Blind, Placebo-Controlled Trial
PubMed ID: 29307112
Randomized trial (200 µg/day chromium) in PCOS showed significant improvements in fasting glucose and HOMA-IR over 8 weeks.
- Controlling type-2 diabetes by inclusion of Cr-enriched yeast bread in the daily dietary pattern: a randomized clinical trial
PubMed ID: 27734127
Chromium‑enriched yeast RCT in T2D showed improvements in fasting glucose, OGTT AUC and HbA1c — strong direct evidence for glycemic benefit.
- Beneficial effects of oral chromium picolinate supplementation on glycemic control in patients with type 2 diabetes: A randomized clinical study
PubMed ID: 26302914
Randomized trial in poorly controlled T2DM: marked reductions in fasting/postprandial glucose and larger HbA1c drop.
- The effect of chromium on inflammatory markers, 1st and 2nd phase insulin secretion in type 2 diabetes
PubMed ID: 23494740
Randomized human trial: chromium chloride improved insulin sensitivity and insulin responsivity in type 2 diabetes (strong direct evidence for glycemic benefit).
- Synchronizing positive effect of vitamin C and chromium on hyper lipidemia, hyperglycemia, liver enzymes and BMI of diabetes mellitus type 2 patients
PubMed ID: 38747270
Diabetics given chromium + vitamin C showed improved HbA1c and glucose‑related outcomes, but chromium was combined with vitamin C so attribution is partial.
- [Assessment of efficiency of dietotherapy with addition of a vitamin-mineral complex in patients with diabetes mellitus type 2]
PubMed ID: 25300112
Vitamin‑mineral complex containing chromium produced larger glucose fall in women with T2D on low‑calorie diet (multi‑nutrient formula).
- The effect of chromium picolinate and biotin supplementation on glycemic control in poorly controlled patients with type 2 diabetes mellitus: a placebo-controlled, double-blinded, randomized trial
PubMed ID: 17109595
Chromium picolinate + biotin reduced OGTT glucose AUC and fructosamine in poorly controlled T2D (direct glycemic benefit).
Fat burn (17)
- Effects of supplemental nanoparticle trivalent chromium on the nutrient utilization, growth performance and serum traits of broilers
PubMed ID: 24947563
Nano chromium picolinate lowered LDL in broilers (animal lipid‑metabolism signal; limited human applicability).
- Effects of Supplemental Chromium Propionate on Serum Lipids, Carcass Traits, and Meat Quality of Heat-Stressed Broilers
PubMed ID: 27660074
Chromium propionate lowered triglycerides and LDL‑C in broilers — animal evidence for effects on lipid metabolism.
- The Influences of Chromium Supplementation on Glycemic Control, Markers of Cardio-Metabolic Risk, and Oxidative Stress in Infertile Polycystic ovary Syndrome Women Candidate for In vitro Fertilization: a Randomized, Double-Blind, Placebo-Controlled Trial
PubMed ID: 29307112
PCOS RCT showed a clinically meaningful drop in triglycerides (~−19 mg/dL), indicating an effect on lipid/fat metabolism.
- A pilot study of the effects of chromium picolinate supplementation on serum fetuin-A, metabolic and inflammatory factors in patients with nonalcoholic fatty liver disease: A double-blind, placebo-controlled trial
PubMed ID: 33045675
Chromium picolinate reduced triglycerides in NAFLD patients — evidence for an effect on lipid (fat) metabolism, though other lipids were unchanged.
- Chromium picolinate balances the metabolic and clinical markers in nonalcoholic fatty liver disease: a randomized, double-blind, placebo-controlled trial
PubMed ID: 32804855
RCT reported decreases in body fat mass and favorable adipokine changes (leptin/adiponectin), indicating meaningful effects on fat/metabolic adipose biology.
- Effect of chromium supplementation on glucose tolerance and lipid profile
PubMed ID: 11533750
Decreased triglycerides and increased HDL suggest favorable effects on lipid/fat metabolism.
- The effects of inorganic chromium and brewer's yeast supplementation on glucose tolerance, serum lipids and drug dosage in individuals with type 2 diabetes
PubMed ID: 11376359
Observed decreases in triglycerides with chromium supplementation indicate an effect on fat-related markers.
- Effects of Chromium and Carnitine Co-supplementation on Body Weight and Metabolic Profiles in Overweight and Obese Women with Polycystic Ovary Syndrome: a Randomized, Double-Blind, Placebo-Controlled Trial
PubMed ID: 30977089
PCOS trial (chromium + carnitine) improved triglycerides and LDL/total cholesterol—multi‑ingredient but supports lipid benefits.
- Chromium picolinate and biotin combination reduces atherogenic index of plasma in patients with type 2 diabetes mellitus: a placebo-controlled, double-blinded, randomized clinical trial
PubMed ID: 17496732
Improved AIP and triglycerides and LDL/HDL ratio with chromium picolinate+biotin, indicating favorable fat‑metabolism effects.
- The effect of chromium picolinate and biotin supplementation on glycemic control in poorly controlled patients with type 2 diabetes mellitus: a placebo-controlled, double-blinded, randomized trial
PubMed ID: 17109595
Chromium picolinate + biotin lowered triglycerides in poorly controlled T2D — direct lipid (fat metabolism) effect.
- Four-week supplementation with a natural dietary compound produces favorable changes in body composition
PubMed ID: 10345151
Multi‑ingredient supplement accelerated fat loss during a diet/exercise program; chromium was a component and may have contributed to fat‑metabolism effects.
- Characterization of the metabolic and physiologic response to chromium supplementation in subjects with type 2 diabetes mellitus
PubMed ID: 20022616
Responders had reductions in myocellular and intrahepatic lipid stores, indicating improved fat handling in tissues.
- In patients with HIV-infection, chromium supplementation improves insulin resistance and other metabolic abnormalities: a randomized, double-blind, placebo controlled trial
PubMed ID: 20163347
Chromium nicotinate lowered triglycerides and reduced body/trunk fat—direct fat‑metabolism/repartitioning signals.
- Beneficial effect of chromium supplementation on glucose, HbA1C and lipid variables in individuals with newly onset type-2 diabetes
PubMed ID: 21570271
Small diabetic trial reported modest improvements in lipids (TC, TG, LDL) with chromium‑containing brewer's yeast.
- [Clinical assessment of dietary correction of metabolic syndrome by using specialized food product enriched with chrome]
PubMed ID: 24006749
Significant weight loss and large LDL‑C decrease in humans imply effects on lipid/fat metabolism or distribution (trial context).
- Chromium picolinate supplementation attenuates body weight gain and increases insulin sensitivity in subjects with type 2 diabetes
PubMed ID: 16873787
Chromium picolinate attenuated visceral fat gain vs placebo in T2DM, suggesting modest effects on fat deposition.
- A comparative study to assess the use of chromium in type 2 diabetes mellitus
PubMed ID: 38024820
Trial reported reductions in total cholesterol and increases in HDL with chromium supplementation, suggesting a favorable effect on lipid/fat metabolism markers.
Nutrient uptake (13)
- A comparative study to assess the use of chromium in type 2 diabetes mellitus
PubMed ID: 38024820
Glycemic improvements are consistent with enhanced insulin‑mediated nutrient handling; trial directly supports improved metabolic handling after chromium.
- The effects of chromium and vitamin D(3) co-supplementation on insulin resistance and tumor necrosis factor-alpha in type 2 diabetes: a randomized placebo-controlled trial
PubMed ID: 31593637
Chromium prevented worsening insulin resistance in T2DM — consistent with improved nutrient (glucose) handling.
- The Influences of Chromium Supplementation on Metabolic Status in Patients with Type 2 Diabetes Mellitus and Coronary Heart Disease
PubMed ID: 31243685
Improved insulin sensitivity (HOMA‑IR, reduced insulin) suggests enhanced cellular nutrient uptake/utilization in diabetics.
- A pilot study of the effects of chromium picolinate supplementation on serum fetuin-A, metabolic and inflammatory factors in patients with nonalcoholic fatty liver disease: A double-blind, placebo-controlled trial
PubMed ID: 33045675
Improved insulin sensitivity (HOMA-IR, QUICKI) implies enhanced cellular handling of glucose/nutrients in chromium picolinate–treated NAFLD patients.
- The effect of chromium on inflammatory markers, 1st and 2nd phase insulin secretion in type 2 diabetes
PubMed ID: 23494740
Improved insulin sensitivity implies enhanced cellular uptake and utilization of nutrients (notably glucose) in T2DM patients treated with chromium chloride.
- The effects of inorganic chromium and brewer's yeast supplementation on glucose tolerance, serum lipids and drug dosage in individuals with type 2 diabetes
PubMed ID: 11376359
Improved glycemic indices suggest enhanced insulin-mediated nutrient handling in diabetics.
- Influence of chromium-enriched yeast on blood glucose and insulin variables, blood lipids, and markers of oxidative stress in subjects with type 2 diabetes mellitus
PubMed ID: 16632892
Chromium‑enriched yeast improved fasting glucose/insulin and some oxidative stress markers, indicating enhanced nutrient/metabolic handling.
- Chromium picolinate supplementation attenuates body weight gain and increases insulin sensitivity in subjects with type 2 diabetes
PubMed ID: 16873787
Improvements in insulin sensitivity/HbA1c on chromium picolinate suggest better utilization of nutrients (glucose).
- Effect of chromium supplementation on productive and reproductive performances and some metabolic parameters in late gestation and early lactation of dairy cows
PubMed ID: 22552822
Dairy cows receiving chromium‑L‑methionine showed increased lactose and reproductive cycling—clear evidence of altered nutrient partitioning/use (animal data).
- [Efficacy of tianmaixiaoke tablets in the treatment of newly diagnosed type 2 diabetes mellitus in China]
PubMed ID: 22944053
Chromium picolinate increased serum chromium and improved HbA1c/HOMA metrics in low‑Cr T2D patients — suggests enhanced insulin-mediated nutrient partitioning.
- Effects of supplemental vitamin C and chromium on metabolic and hormonal responses, antioxidant status, and tonic immobility reactions of transported broiler chickens
PubMed ID: 24446191
Poultry study showed altered insulin and antioxidant markers with chromium, consistent with improved nutrient handling/utilization in that model.
- Effects of supplemental nanoparticle trivalent chromium on the nutrient utilization, growth performance and serum traits of broilers
PubMed ID: 24947563
NanoCrPic increased chromium utilization relative to other forms in broilers (clear nutrient‑use effect in animals).
- Dietary chromium methionine supplementation could alleviate immunosuppressive effects of heat stress in broiler chicks
PubMed ID: 26440004
Chromium‑methionine improved feed efficiency and growth in heat‑stressed broiler chicks (enhanced nutrient utilization in animals).
Heart health (10)
- Effect of chromium supplementation on glucose tolerance and lipid profile
PubMed ID: 11533750
CrCl3 (200 µg/day) improved triglycerides and increased HDL in adults—directly relevant to heart health markers.
- Synchronizing positive effect of vitamin C and chromium on hyper lipidemia, hyperglycemia, liver enzymes and BMI of diabetes mellitus type 2 patients
PubMed ID: 38747270
Diabetic patients receiving chromium+vitamin C had improved LDL and other metabolic markers relevant to cardiovascular risk, but chromium not isolated.
- Effects of niacin-bound chromium and grape seed proanthocyanidin extract on the lipid profile of hypercholesterolemic subjects: a pilot study
PubMed ID: 11508317
Niacin‑bound chromium lowered total and LDL cholesterol (~10–14%) in hypercholesterolemic adults — relevant to heart risk factors.
- Chromium picolinate and biotin combination reduces atherogenic index of plasma in patients with type 2 diabetes mellitus: a placebo-controlled, double-blinded, randomized clinical trial
PubMed ID: 17496732
Chromium picolinate+biotin improved atherogenic index, triglycerides and LDL/HDL ratios in obese T2D subjects (lipid improvements relevant to heart health).
- Elevated intakes of supplemental chromium improve glucose and insulin variables in individuals with type 2 diabetes
PubMed ID: 9356027
High-dose chromium picolinate reduced total cholesterol in T2DM trial — plausible indirect benefit for heart health via lipid improvement.
- The effects of inorganic chromium and brewer's yeast supplementation on glucose tolerance, serum lipids and drug dosage in individuals with type 2 diabetes
PubMed ID: 11376359
Observed decreases in triglycerides with chromium supplementation in type 2 diabetes support cardiovascular risk improvement.
- [Clinical assessment of dietary correction of metabolic syndrome by using specialized food product enriched with chrome]
PubMed ID: 24006749
Human trial reported large systolic BP reduction (−20.5%) and LDL‑C lowering (−28.3%), both relevant to cardiovascular risk.
- Chromium Exposure and Risk of Cardiovascular Disease in High Cardiovascular Risk Subjects - Nested Case-Control Study in the Prevention With Mediterranean Diet (PREDIMED) Study
PubMed ID: 28392547
Nested case-control study: higher toenail chromium associated with lower incident CVD in non-diabetic subgroup (statistically significant), suggesting possible cardiovascular benefit of higher chromium exposure.
- Chromium Supplementation Reduces Resting Heart Rate in Patients with Metabolic Syndrome and Impaired Glucose Tolerance
PubMed ID: 28856601
Chromium yeast lowered resting heart rate in metabolic-syndrome/IGT participants, implying reduced sympathetic drive and a potential cardiac-autonomic effect.
- Improving the endothelial dysfunction in type 2 diabetes with chromium and vitamin D(3) byreducing homocysteine and oxidative stress: A randomized placebo-controlled trial
PubMed ID: 32971450
Chromium (±vit D) lowered endothelial/inflammatory markers (VCAM‑1, homocysteine) in T2DM patients—mechanistically supportive for vascular/heart health.
Weight management (11)
- Controlling type-2 diabetes by inclusion of Cr-enriched yeast bread in the daily dietary pattern: a randomized clinical trial
PubMed ID: 27734127
Chromium‑enriched yeast RCT reported weight reduction along with improved glycemia in T2D patients.
- Four-week supplementation with a natural dietary compound produces favorable changes in body composition
PubMed ID: 10345151
Randomized double‑blind trial: multi‑ingredient product containing chromium picolinate accelerated fat loss and preserved lean mass during a diet/exercise program; chromium was one component so effect attribution is partial.
- [Clinical assessment of dietary correction of metabolic syndrome by using specialized food product enriched with chrome]
PubMed ID: 24006749
Small human RCT of chromium‑enriched seaweed jam found a clinically meaningful body mass reduction (≈−5%).
- Chromium supplementation alters the performance and health of feedlot cattle during the receiving period and enhances their metabolic response to a lipopolysaccharide challenge
PubMed ID: 22665638
Feedlot steers supplemented with chromium showed improved ADG and reduced acute weight loss after challenge—strong animal evidence for body‑weight effects (direction: gain).
- In patients with HIV-infection, chromium supplementation improves insulin resistance and other metabolic abnormalities: a randomized, double-blind, placebo controlled trial
PubMed ID: 20163347
Chromium nicotinate modestly reduced total body fat and trunk fat over 16 weeks in insulin‑resistant HIV patients.
- Effects of chromium picolinate on food intake and satiety
PubMed ID: 18715218
CrPic reduced calorie intake and hunger with a trend toward weight reduction in overweight women.
- Chromium picolinate supplementation attenuates body weight gain and increases insulin sensitivity in subjects with type 2 diabetes
PubMed ID: 16873787
Chromium picolinate limited overall weight gain and visceral fat increase vs placebo in T2DM on sulfonylurea.
- Effects of Chromium and Carnitine Co-supplementation on Body Weight and Metabolic Profiles in Overweight and Obese Women with Polycystic Ovary Syndrome: a Randomized, Double-Blind, Placebo-Controlled Trial
PubMed ID: 30977089
RCT reported clinically meaningful weight loss (~−3.6 kg) in supplemented group, but chromium was combined with carnitine so attribution to chromium alone is uncertain.
- Chromium picolinate reduces insulin resistance in polycystic ovary syndrome: Randomized controlled trial
PubMed ID: 26663540
6‑month PCOS RCT produced a significant BMI reduction (direct human evidence for weight change).
- Chromium picolinate balances the metabolic and clinical markers in nonalcoholic fatty liver disease: a randomized, double-blind, placebo-controlled trial
PubMed ID: 32804855
12-week RCT of chromium picolinate in NAFLD showed decreases in body weight and body fat mass versus placebo — direct evidence supporting modest weight/body-fat effects.
- Efficacy of a novel calcium/potassium salt of (-)-hydroxycitric acid in weight control
PubMed ID: 16366421
Combination including niacin‑bound chromium produced larger weight loss and lipid improvements vs HCA alone in obese subjects (multi‑ingredient evidence).
Appetite suppression (5)
- Effects of supplemental chromium propionate and rumen-protected amino acids on productivity, diet digestibility, and energy balance of peak-lactation dairy cattle
PubMed ID: 24731641
Chromium propionate increased dry‑matter intake in lactating cows (clear appetite/feeding effect in animals).
- A double-blind, placebo-controlled, exploratory trial of chromium picolinate in atypical depression: effect on carbohydrate craving
PubMed ID: 16184071
RCT showed chromium picolinate reduced carbohydrate craving and improved response in high‑craving patients (direct human evidence for lowering sugar/carbohydrate craving).
- Effects of chromium picolinate on food intake and satiety
PubMed ID: 18715218
Human RCT: chromium picolinate significantly reduced food intake, hunger and fat cravings in overweight women.
- Effects of chromium propionate supplementation during the periparturient period and early lactation on metabolism, performance, and cytological endometritis in dairy cows
PubMed ID: 25087037
Periparturient dairy cows given chromium propionate tended to have improved prepartum feed intake (directly relevant to appetite control in that model).
- Dietary chromium methionine supplementation could alleviate immunosuppressive effects of heat stress in broiler chicks
PubMed ID: 26440004
Broiler study reported increased feed intake with chromium‑methionine (direct appetite effect in animals).
Muscle maintenance (4)
- A Dietary Supplement Containing Cinnamon, Chromium and Carnosine Decreases Fasting Plasma Glucose and Increases Lean Mass in Overweight or Obese Pre-Diabetic Subjects: A Randomized, Placebo-Controlled Trial
PubMed ID: 26406981
Trial including chromium (with cinnamon and carnosine) increased fat‑free mass (+1.2 kg), suggesting possible support for lean mass maintenance/gain.
- Four-week supplementation with a natural dietary compound produces favorable changes in body composition
PubMed ID: 10345151
Multi‑ingredient supplement (including chromium picolinate) helped preserve fat‑free mass during diet/exercise, indicating a role in lean‑mass maintenance though chromium was not isolated.
- Effects of dietary supplementation of organic chromium (picolinate) on physical and biochemical characteristics of semen and carcass traits of male turkeys
PubMed ID: 25458321
Chromium picolinate in male turkeys improved carcass yield measures (animal evidence suggesting effects on lean mass/composition).
- [Effect of chromium yeast and chromium picolinate on body composition of obese, non-diabetic patients during and after a formula diet]
PubMed ID: 9480618
Chromium picolinate increased lean body mass during the maintenance period after VLCD — direct support for lean-mass preservation.
Hair & Nails (2)
- The Effects of Chromium Supplementation on Endocrine Profiles, Biomarkers of Inflammation, and Oxidative Stress in Women with Polycystic Ovary Syndrome: a Randomized, Double-Blind, Placebo-Controlled Trial
PubMed ID: 26613790
8‑week RCT in women with PCOS showed a significant reduction in hirsutism scores (direct hair/skin outcome).
- Dietary Intervention for Control of Clinical Symptom in Patients with Systemic Metal Allergy: A Single Center Randomized Controlled Clinical Study
PubMed ID: 38379275
Randomized dietary intervention reducing nickel/cobalt/chromium intake improved eczema in metal‑allergic patients, showing chromium exposure can affect skin in sensitized individuals (not a supplementation benefit).
Healthy aging (1)
- Improving the endothelial dysfunction in type 2 diabetes with chromium and vitamin D(3) byreducing homocysteine and oxidative stress: A randomized placebo-controlled trial
PubMed ID: 32971450
Randomized trial showed reductions in oxidative stress markers (MDA) and homocysteine with chromium (±vit D), which are plausibly relevant to healthy aging.
Similar by evidence
Supplements the same benefits carry qualifying findings for — a fact about the evidence graph, not a recommendation to swap.
Products with Chromium
Search all11848 products whose verified label declares Chromium — not every bottle that mentions it in a title.
Being studied right now
Recruiting clinical trials registered on ClinicalTrials.gov. A trial in progress has no result yet — this is what the field is asking, not what it found.