Akkermansia muciniphila
14 benefits mapped to clinical evidence across supplements.
Dose per serving from products
98 products in our catalogue print how much Akkermansia muciniphila a serving holds.
Most common: 250 billion CFU to 500 billion CFU, 22% of 98 products.
| Dose per serving | Products |
|---|---|
| 0.05 billion CFU or less | 1 |
| 0.05 billion CFU to 0.1 billion CFU | 15 |
| 0.1 billion CFU to 0.25 billion CFU | 1 |
| 0.25 billion CFU to 0.5 billion CFU | 1 |
| 0.5 billion CFU to 1 billion CFU | 11 |
| 1 billion CFU to 2.5 billion CFU | 10 |
| 2.5 billion CFU to 5 billion CFU | 8 |
| 5 billion CFU to 10 billion CFU | 11 |
| 10 billion CFU to 25 billion CFU | 8 |
| 25 billion CFU to 50 billion CFU | 3 |
| 50 billion CFU to 100 billion CFU | 4 |
| 100 billion CFU to 250 billion CFU | 3 |
| 250 billion CFU to 500 billion CFU | 22 |
Benefit Evidence
Immune markers ↓, +50% TGF-β1
MDRO/AMR burden ↓, A. muciniphila
Symptoms improved, no safety issues
Immune markers ↓, +50% TGF-β1
MDRO/AMR burden ↓, A. muciniphila
Symptoms improved, no safety issues
Research sources
Gut health (21)
- Effect of Lacticaseibacillus rhamnosus IDCC 3201 on irritable bowel syndrome with constipation: a randomized, double-blind, and placebo-controlled trial
PubMed ID: 39333245
Probiotic improved IBS symptoms and enriched Akkermansia plus specific fecal metabolites—direct flora improvement evidence.
- Gut microbiome and metabolome alterations in traditional Chinese medicine damp-heat constitution following treatment with a Chinese patent medicine and lifestyle intervention
PubMed ID: 38851100
Ermiao Pill + lifestyle enriched Akkermansia and beneficial metabolites—evidence of improved gut flora.
- Akkermansia muciniphila supplementation in patients with overweight/obese type 2 diabetes: Efficacy depends on its baseline levels in the gut
PubMed ID: 39879980
Direct supplementation with live A. muciniphila achieved colonization in low-baseline subjects—strong flora-modifying evidence.
- Multi-species probiotic supplement enhances vagal nerve function - results of a randomized controlled trial in patients with depression and healthy controls
PubMed ID: 40298641
Probiotic increased Akkermansia abundance in depressed patients after 12 weeks—supports flora improvement.
- Comparing the effects of yogurt containing Akkermansia muciniphilia postbiotic with yogurt containing Lactobacillus rhamnosus postbiotic on body composition, biochemical indices, appetite, and depression scores in overweight or obese adults: A randomized, double-blind, controlled clinical trial
PubMed ID: 40451504
Yogurt fortified with A. muciniphila postbiotic modified anthropometrics and implies beneficial gut flora action.
- Effects of home-based exercise training on gut microbiota and possible relations with cognitive function and metabolic health in postmenopausal women with type 2 diabetes mellitus: a randomized control trial
PubMed ID: 41109629
Exercise raised Akkermansia levels in T2D postmenopausal women—supportive of flora improvements via lifestyle.
- A yeast fermentate improves gastrointestinal discomfort and constipation by modulation of the gut microbiome: results from a randomized double-blind placebo-controlled pilot trial
PubMed ID: 28870194
EpiCor trial increased Akkermansia and improved bowel habits in a subgroup—microbiome and function both altered.
- Diets that differ in their FODMAP content alter the colonic luminal microenvironment
PubMed ID: 25016597
FODMAP dietary changes markedly altered A. muciniphila and total bacterial abundance—strong diet‑microbiome link.
- Efficacy of Lactococcus lactis subsp. lactis LY-66 and Lactobacillus plantarum PL-02 in Enhancing Explosive Strength and Endurance: A Randomized, Double-Blinded Clinical Trial
PubMed ID: 38931275
Athlete-derived probiotics increased Akkermansia in some groups and improved fitness—shows beneficial flora modulation.
- Clinical efficacy of weight loss herbal intervention therapy and lifestyle modifications on obesity and its association with distinct gut microbiome: A randomized double-blind phase 2 study
PubMed ID: 37033234
Randomized trial showed increased A. muciniphila abundance associated with clinical improvements—strong evidence of favorable flora change.
- Resistant Maltodextrin Consumption in a Double-Blind, Randomized, Crossover Clinical Trial Induces Specific Changes in Potentially Beneficial Gut Bacteria
PubMed ID: 35683992
Resistant maltodextrin raised beneficial bacteria and produced borderline increases in Akkermansia in low‑baseline individuals.
- Changes in the intestinal microbiota of healthy adults induced by brown yogurt and relationships of bacterial taxa with specific components
PubMed ID: 35521810
Brown yogurt formulation increased A. muciniphila and shifted other gut taxa in healthy adults.
- Increased circulating butyrate and ursodeoxycholate during probiotic intervention in humans with type 2 diabetes
PubMed ID: 34996347
Multi‑strain probiotic (including Akkermansia) raised plasma butyrate and UDCA with microbiome‑linked metabolic effects.
- The Prebiotic Effects of Oats on Blood Lipids, Gut Microbiota, and Short-Chain Fatty Acids in Mildly Hypercholesterolemic Subjects Compared With Rice: A Randomized, Controlled Trial
PubMed ID: 34956218
Oats (β‑glucan) increased A.m and SCFAs in a randomized trial — dietary promotion of beneficial flora and metabolites.
- Genistein stimulates insulin sensitivity through gut microbiota reshaping and skeletal muscle AMPK activation in obese subjects
PubMed ID: 32152146
Genistein markedly reduced circulating LPS and improved insulin sensitivity, supporting barrier integrity.
- Improvements to postprandial glucose control in subjects with type 2 diabetes: a multicenter, double blind, randomized placebo-controlled trial of a novel probiotic formulation
PubMed ID: 32675291
Targeted probiotic containing Akkermansia and butyrate producers increased stool detection of strains and improved glucose control.
- Improvement of Lipoprotein Profile and Metabolic Endotoxemia by a Lifestyle Intervention That Modifies the Gut Microbiota in Subjects With Metabolic Syndrome
PubMed ID: 31451009
Lifestyle/functional‑food program in MetS raised A.m and decreased LPS — supports reduced endotoxemia/stronger barrier.
- Investigation the effect of oleoylethanolamide supplementation on the abundance of Akkermansia muciniphila bacterium and the dietary intakes in people with obesity: A randomized clinical trial
PubMed ID: 31132422
OEA capsules increased fecal A.m and reduced intake in obese adults — demonstrates microbiome modulation by a supplement.
- Supplementation with Akkermansia muciniphila in overweight and obese human volunteers: a proof-of-concept exploratory study
PubMed ID: 31263284
Direct oral A. muciniphila supplementation increased fecal A. muciniphila and produced metabolic benefits—direct evidence of engraftment/impact.
- A dietary intervention with functional foods reduces metabolic endotoxaemia and attenuates biochemical abnormalities by modifying faecal microbiota in people with type 2 diabetes
PubMed ID: 30266575
Functional‑food diet increased Akkermansia and reduced endotoxemia (LPS) in people with T2D.
- Fecal Akkermansia muciniphila Is Associated with Body Composition and Microbiota Diversity in Overweight and Obese Women with Breast Cancer Participating in a Presurgical Weight Loss Trial
PubMed ID: 30420171
Higher A.m associated with greater microbiota diversity and lower fat mass — supportive of healthier flora.
Weight management (12)
- The Prebiotic Effects of Oats on Blood Lipids, Gut Microbiota, and Short-Chain Fatty Acids in Mildly Hypercholesterolemic Subjects Compared With Rice: A Randomized, Controlled Trial
PubMed ID: 34956218
Oats raised A.m and SCFAs and improved cholesterol — dietary fiber produced A.m‑mediated metabolic responses.
- Mediterranean diet consumption affects the endocannabinoid system in overweight and obese subjects: possible links with gut microbiome, insulin resistance and inflammation
PubMed ID: 33763720
Mediterranean diet changed endocannabinoid markers and increased A.m — links diet composition, A.m and metabolic signalling.
- Clinical efficacy of weight loss herbal intervention therapy and lifestyle modifications on obesity and its association with distinct gut microbiome: A randomized double-blind phase 2 study
PubMed ID: 37033234
Randomized trial with significant weight/BMI reductions concomitant with increased A. muciniphila.
- Akkermansia muciniphila supplementation in patients with overweight/obese type 2 diabetes: Efficacy depends on its baseline levels in the gut
PubMed ID: 39879980
Live A. muciniphila reduced body weight and fat mass in low-baseline T2D patients—strong direct evidence.
- Comparing the effects of yogurt containing Akkermansia muciniphilia postbiotic with yogurt containing Lactobacillus rhamnosus postbiotic on body composition, biochemical indices, appetite, and depression scores in overweight or obese adults: A randomized, double-blind, controlled clinical trial
PubMed ID: 40451504
A. muciniphila postbiotic yogurt reduced waist, WHtR and body fat percent in overweight adults.
- A dietary intervention with functional foods reduces metabolic endotoxaemia and attenuates biochemical abnormalities by modifying faecal microbiota in people with type 2 diabetes
PubMed ID: 30266575
Functional‑food intervention in T2D raised A.m and improved HbA1c/endotoxaemia — demonstrates diet‑dependent response linked to A.m.
- Fecal Akkermansia muciniphila Is Associated with Body Composition and Microbiota Diversity in Overweight and Obese Women with Breast Cancer Participating in a Presurgical Weight Loss Trial
PubMed ID: 30420171
In overweight women, higher stool Akkermansia correlated with substantially lower fat mass (observational within trial).
- Diets that differ in their FODMAP content alter the colonic luminal microenvironment
PubMed ID: 25016597
Randomized FODMAP crossover produced large, rapid changes in Akkermansia—demonstrates diet responsiveness of this species.
- Supplementation with Akkermansia muciniphila in overweight and obese human volunteers: a proof-of-concept exploratory study
PubMed ID: 31263284
Human supplementation improved insulin and endotoxin measures that favor weight‑related metabolic health.
- Investigation the effect of oleoylethanolamide supplementation on the abundance of Akkermansia muciniphila bacterium and the dietary intakes in people with obesity: A randomized clinical trial
PubMed ID: 31132422
OEA increased Akkermansia and reduced energy/carbohydrate intake in obese adults, supporting appetite/weight control.
- Improvement of Lipoprotein Profile and Metabolic Endotoxemia by a Lifestyle Intervention That Modifies the Gut Microbiota in Subjects With Metabolic Syndrome
PubMed ID: 31451009
Functional‑food + activity program raised Akkermansia and improved metabolic markers indicating enhanced diet response in MetS.
- Genistein stimulates insulin sensitivity through gut microbiota reshaping and skeletal muscle AMPK activation in obese subjects
PubMed ID: 32152146
Genistein raised A.m and improved insulin and oxidative metabolism — supplement‑diet interaction showing enhanced response.
Metabolism (12)
- Beneficial Effects of Akkermansia muciniphila Are Not Associated with Major Changes in the Circulating Endocannabinoidome but Linked to Higher Mono-Palmitoyl-Glycerol Levels as New PPARα Agonists
PubMed ID: 33477821
Supplementation raised 1‑/2‑palmitoyl‑glycerols (PPARα agonists) which stimulate fatty‑acid oxidation.
- Increased circulating butyrate and ursodeoxycholate during probiotic intervention in humans with type 2 diabetes
PubMed ID: 34996347
WBF‑011 probiotic including A.m increased butyrate/UDCA and correlated with improved HbA1c in responders — metabolic improvement signal.
- Clinical efficacy of weight loss herbal intervention therapy and lifestyle modifications on obesity and its association with distinct gut microbiome: A randomized double-blind phase 2 study
PubMed ID: 37033234
Weight/BMI reductions with increased Akkermansia suggest lowered metabolic risk.
- Akkermansia muciniphila supplementation in patients with overweight/obese type 2 diabetes: Efficacy depends on its baseline levels in the gut
PubMed ID: 39879980
Live A. muciniphila reduced weight/fat and HbA1c in T2D—strong evidence for lowering metabolic risk in responsive subjects.
- Comparing the effects of yogurt containing Akkermansia muciniphilia postbiotic with yogurt containing Lactobacillus rhamnosus postbiotic on body composition, biochemical indices, appetite, and depression scores in overweight or obese adults: A randomized, double-blind, controlled clinical trial
PubMed ID: 40451504
A. muciniphila–fortified yogurt reduced waist and body fat percent—supports improved metabolic profile.
- A dietary intervention with functional foods reduces metabolic endotoxaemia and attenuates biochemical abnormalities by modifying faecal microbiota in people with type 2 diabetes
PubMed ID: 30266575
Functional‑food RCT in T2D raised A.m and improved HbA1c and endotoxaemia.
- The Prebiotic Effects of Oats on Blood Lipids, Gut Microbiota, and Short-Chain Fatty Acids in Mildly Hypercholesterolemic Subjects Compared With Rice: A Randomized, Controlled Trial
PubMed ID: 34956218
Oats increased Akkermansia and SCFAs and lowered total/LDL cholesterol—cardiometabolic risk improvement.
- Serum metabolite profiling yields insights into health promoting effect of A. muciniphila in human volunteers with a metabolic syndrome
PubMed ID: 34812127
Serum metabolome after A. muciniphila showed increased ketone and fatty‑acid oxidation markers indicating raised metabolic rate.
- Genistein stimulates insulin sensitivity through gut microbiota reshaping and skeletal muscle AMPK activation in obese subjects
PubMed ID: 32152146
Genistein increased Akkermansia, reduced HOMA‑IR and circulating LPS—strong reduction in metabolic risk markers.
- Improvements to postprandial glucose control in subjects with type 2 diabetes: a multicenter, double blind, randomized placebo-controlled trial of a novel probiotic formulation
PubMed ID: 32675291
Targeted probiotic with A.m improved postprandial glucose AUC and trended to reduce A1c — supports reduced metabolic risk.
- Improvement of Lipoprotein Profile and Metabolic Endotoxemia by a Lifestyle Intervention That Modifies the Gut Microbiota in Subjects With Metabolic Syndrome
PubMed ID: 31451009
Functional‑food + activity lowered endotoxaemia and favorably changed lipoprotein particles in metabolic syndrome.
- Supplementation with Akkermansia muciniphila in overweight and obese human volunteers: a proof-of-concept exploratory study
PubMed ID: 31263284
A. muciniphila supplementation improved insulin measures and lowered LPS—markers of lower cardiometabolic risk.
Blood sugar (9)
- Improvement of Lipoprotein Profile and Metabolic Endotoxemia by a Lifestyle Intervention That Modifies the Gut Microbiota in Subjects With Metabolic Syndrome
PubMed ID: 31451009
Lifestyle/functional‑food program in MetS improved metabolic markers and raised A.m — supportive evidence for lower metabolic/glycemic risk.
- Supplementation with Akkermansia muciniphila in overweight and obese human volunteers: a proof-of-concept exploratory study
PubMed ID: 31263284
Three‑month oral A. muciniphila (live/pasteurized) improved fasting insulin and insulin resistance markers in humans.
- Akkermansia muciniphila supplementation in patients with overweight/obese type 2 diabetes: Efficacy depends on its baseline levels in the gut
PubMed ID: 39879980
Live A. muciniphila improved HbA1c and glycemic control in low-baseline T2D subjects—strong direct evidence.
- Clinical efficacy of weight loss herbal intervention therapy and lifestyle modifications on obesity and its association with distinct gut microbiome: A randomized double-blind phase 2 study
PubMed ID: 37033234
Herbal+lifestyle group had metabolic improvements; glycemic measures improved alongside increased A. muciniphila (metabolic link plausible).
- Increased circulating butyrate and ursodeoxycholate during probiotic intervention in humans with type 2 diabetes
PubMed ID: 34996347
Multi‑strain probiotic (including Akkermansia) raised butyrate/UDCA and correlated with glycemic improvements in T2D responders.
- Adjuvant Probiotics of Lactobacillus salivarius subsp. salicinius AP-32, L. johnsonii MH-68, and Bifidobacterium animalis subsp. lactis CP-9 Attenuate Glycemic Levels and Inflammatory Cytokines in Patients With Type 1 Diabetes Mellitus
PubMed ID: 35299968
Adjunct probiotic in T1D decreased fasting glucose and HbA1c while raising Akkermansia and lowering inflammation.
- Genistein stimulates insulin sensitivity through gut microbiota reshaping and skeletal muscle AMPK activation in obese subjects
PubMed ID: 32152146
Genistein markedly improved insulin sensitivity (HOMA‑IR) while increasing Akkermansia.
- Improvements to postprandial glucose control in subjects with type 2 diabetes: a multicenter, double blind, randomized placebo-controlled trial of a novel probiotic formulation
PubMed ID: 32675291
Targeted probiotic including Akkermansia improved post‑meal glucose AUC and tended to lower A1c in T2D.
- A dietary intervention with functional foods reduces metabolic endotoxaemia and attenuates biochemical abnormalities by modifying faecal microbiota in people with type 2 diabetes
PubMed ID: 30266575
Functional‑food RCT in T2D increased Akkermansia and improved HbA1c and endotoxaemia.
Inflammation (7)
- Increased circulating butyrate and ursodeoxycholate during probiotic intervention in humans with type 2 diabetes
PubMed ID: 34996347
Multi‑strain probiotic including A.m increased butyrate and UDCA and correlated with improved glycemic control — anti‑inflammatory bile acid shifts.
- Akkermansia muciniphila supplementation in patients with overweight/obese type 2 diabetes: Efficacy depends on its baseline levels in the gut
PubMed ID: 39879980
Live A. muciniphila improved glycemic/weight outcomes in T2D, which commonly coincide with reduced systemic inflammation.
- A dietary intervention with functional foods reduces metabolic endotoxaemia and attenuates biochemical abnormalities by modifying faecal microbiota in people with type 2 diabetes
PubMed ID: 30266575
Dietary intervention raised Akkermansia and reduced metabolic endotoxaemia (LPS) in T2D patients.
- Supplementation with Akkermansia muciniphila in overweight and obese human volunteers: a proof-of-concept exploratory study
PubMed ID: 31263284
A. muciniphila supplementation lowered plasma LPS, a driver of systemic inflammation in humans.
- Improvement of Lipoprotein Profile and Metabolic Endotoxemia by a Lifestyle Intervention That Modifies the Gut Microbiota in Subjects With Metabolic Syndrome
PubMed ID: 31451009
Lifestyle/functional food program reduced plasma LPS and improved metabolic inflammation markers in MetS.
- Genistein stimulates insulin sensitivity through gut microbiota reshaping and skeletal muscle AMPK activation in obese subjects
PubMed ID: 32152146
Genistein increased Akkermansia and sharply reduced circulating LPS and inflammatory markers.
- Adjuvant Probiotics of Lactobacillus salivarius subsp. salicinius AP-32, L. johnsonii MH-68, and Bifidobacterium animalis subsp. lactis CP-9 Attenuate Glycemic Levels and Inflammatory Cytokines in Patients With Type 1 Diabetes Mellitus
PubMed ID: 35299968
Adjunct probiotic in T1D raised Akkermansia and produced large reductions in pro‑inflammatory cytokines.
Fat burn (4)
- Comparing the effects of yogurt containing Akkermansia muciniphilia postbiotic with yogurt containing Lactobacillus rhamnosus postbiotic on body composition, biochemical indices, appetite, and depression scores in overweight or obese adults: A randomized, double-blind, controlled clinical trial
PubMed ID: 40451504
A. muciniphila postbiotic yogurt significantly reduced waist circumference and body fat percent in overweight adults.
- Akkermansia muciniphila supplementation in patients with overweight/obese type 2 diabetes: Efficacy depends on its baseline levels in the gut
PubMed ID: 39879980
Live A. muciniphila reduced body weight and fat mass in low-baseline T2D participants—applicable to abdominal fat.
- Clinical efficacy of weight loss herbal intervention therapy and lifestyle modifications on obesity and its association with distinct gut microbiome: A randomized double-blind phase 2 study
PubMed ID: 37033234
Herbal+lifestyle trial produced larger weight/BMI loss versus placebo concurrent with increased A. muciniphila.
- Fecal Akkermansia muciniphila Is Associated with Body Composition and Microbiota Diversity in Overweight and Obese Women with Breast Cancer Participating in a Presurgical Weight Loss Trial
PubMed ID: 30420171
Higher fecal Akkermansia in overweight women linked to ~7.5 kg less fat mass (observational within trial).
Liver support (4)
- Increased circulating butyrate and ursodeoxycholate during probiotic intervention in humans with type 2 diabetes
PubMed ID: 34996347
Multi‑strain probiotic including Akkermansia raised circulating UDCA and glyco‑UDCA (bile acids relevant to liver health) and associated with glycemic benefit.
- Beneficial Effects of Akkermansia muciniphila Are Not Associated with Major Changes in the Circulating Endocannabinoidome but Linked to Higher Mono-Palmitoyl-Glycerol Levels as New PPARα Agonists
PubMed ID: 33477821
A.m increased PPARα‑activating lipids that have hepatic metabolic effects — mechanistic support for hepatic benefits.
- Serum metabolite profiling yields insights into health promoting effect of A. muciniphila in human volunteers with a metabolic syndrome
PubMed ID: 34812127
A. muciniphila changed serum metabolites toward increased β‑oxidation and ketone bodies—metabolic effects relevant to liver fat handling.
- Comparing the effects of yogurt containing Akkermansia muciniphilia postbiotic with yogurt containing Lactobacillus rhamnosus postbiotic on body composition, biochemical indices, appetite, and depression scores in overweight or obese adults: A randomized, double-blind, controlled clinical trial
PubMed ID: 40451504
A. muciniphila–fortified yogurt reduced AST, a liver enzyme—direct evidence of liver benefit.
Cholesterol (3)
- Effects of home-based exercise training on gut microbiota and possible relations with cognitive function and metabolic health in postmenopausal women with type 2 diabetes mellitus: a randomized control trial
PubMed ID: 41109629
Exercise program increased HDL and raised Akkermansia—direct evidence for improved cholesterol profile (HDL).
- The Prebiotic Effects of Oats on Blood Lipids, Gut Microbiota, and Short-Chain Fatty Acids in Mildly Hypercholesterolemic Subjects Compared With Rice: A Randomized, Controlled Trial
PubMed ID: 34956218
Oats (β‑glucan) trial increased Akkermansia and produced significant reductions in total and LDL cholesterol.
- Improvement of Lipoprotein Profile and Metabolic Endotoxemia by a Lifestyle Intervention That Modifies the Gut Microbiota in Subjects With Metabolic Syndrome
PubMed ID: 31451009
Functional‑food + activity program lowered LPS and improved small LDL/HDL particle profiles alongside raised Akkermansia.
Energy & Fatigue (3)
- Pasteurized Akkermansia muciniphila HB05 (HB05P) Improves Muscle Strength and Function: A 12-Week, Randomized, Double-Blind, Placebo-Controlled Clinical Trial
PubMed ID: 39683431
Improved leg muscle strength in older adults plausibly increases functional energy and capacity.
- Serum metabolite profiling yields insights into health promoting effect of A. muciniphila in human volunteers with a metabolic syndrome
PubMed ID: 34812127
Metabolome shifts after A. muciniphila indicated increased ketone bodies and fatty‑acid oxidation—substrates for energy.
- Efficacy of Lactococcus lactis subsp. lactis LY-66 and Lactobacillus plantarum PL-02 in Enhancing Explosive Strength and Endurance: A Randomized, Double-Blinded Clinical Trial
PubMed ID: 38931275
Athlete probiotic trial raised VO2max and explosive strength—objective markers of improved energetic capacity.
Focus & concentration (3)
- Effects of home-based exercise training on gut microbiota and possible relations with cognitive function and metabolic health in postmenopausal women with type 2 diabetes mellitus: a randomized control trial
PubMed ID: 41109629
Exercise program in T2D increased Akkermansia and was linked to better cognition—direct cognitive benefit evidence.
- A randomized, placebo-controlled trial investigating the acute and chronic benefits of American Ginseng (Cereboost®) on mood and cognition in healthy young adults, including in vitro investigation of gut microbiota changes as a possible mechanism of action
PubMed ID: 34396468
American ginseng improved attention/working memory in humans; in vitro gut simulation increased Akkermansia and SCFAs suggesting a microbiome‑mediated mechanism.
- Multi-species probiotic supplement enhances vagal nerve function - results of a randomized controlled trial in patients with depression and healthy controls
PubMed ID: 40298641
Multispecies probiotic increased vagal HRV and Akkermansia in depressed patients, with improved depression measures—direct support for mood-related benefit.
Appetite suppression (3)
- Mediterranean diet consumption affects the endocannabinoid system in overweight and obese subjects: possible links with gut microbiome, insulin resistance and inflammation
PubMed ID: 33763720
Mediterranean diet altered endocannabinoid markers (AEA/OEA ratios) and increased A.m — biological link to satiety/appetite regulation.
- Investigation the effect of oleoylethanolamide supplementation on the abundance of Akkermansia muciniphila bacterium and the dietary intakes in people with obesity: A randomized clinical trial
PubMed ID: 31132422
Oleoylethanolamide increased Akkermansia and reduced energy and carbohydrate intake in obese adults.
- Comparing the effects of yogurt containing Akkermansia muciniphilia postbiotic with yogurt containing Lactobacillus rhamnosus postbiotic on body composition, biochemical indices, appetite, and depression scores in overweight or obese adults: A randomized, double-blind, controlled clinical trial
PubMed ID: 40451504
Postbiotic-fortified yogurt significantly decreased reported appetite scores—direct evidence for appetite control.
Digestive support (3)
- Effect of Lacticaseibacillus rhamnosus IDCC 3201 on irritable bowel syndrome with constipation: a randomized, double-blind, and placebo-controlled trial
PubMed ID: 39333245
Tyndallized L. rhamnosus significantly improved IBS-SSS and increased Akkermansia—direct evidence for digestive symptom improvement.
- A yeast fermentate improves gastrointestinal discomfort and constipation by modulation of the gut microbiome: results from a randomized double-blind placebo-controlled pilot trial
PubMed ID: 28870194
Yeast fermentate trial improved bowel frequency/consistency and increased A. muciniphila in symptomatic subgroup.
- Diets that differ in their FODMAP content alter the colonic luminal microenvironment
PubMed ID: 25016597
High vs low FODMAP diets produced large shifts in mucus‑associated A. muciniphila and stool environment relevant to digestion.
Immune support (2)
- Adjuvant Probiotics of Lactobacillus salivarius subsp. salicinius AP-32, L. johnsonii MH-68, and Bifidobacterium animalis subsp. lactis CP-9 Attenuate Glycemic Levels and Inflammatory Cytokines in Patients With Type 1 Diabetes Mellitus
PubMed ID: 35299968
Probiotic adjunct in T1D raised Akkermansia and produced broad reductions in pro‑inflammatory cytokines and increased TGF‑β1.
- Efficacy of ETB-F01, Heat-Killed Akkermansia muciniphila Strain EB-AMDK19, in Patients with Respiratory Symptoms: A Multicenter Clinical Trial
PubMed ID: 39683507
Heat-killed A. muciniphila reduced cough and breathlessness—suggests immune/airway inflammatory modulation.
Healthy aging (1)
- Pasteurized Akkermansia muciniphila HB05 (HB05P) Improves Muscle Strength and Function: A 12-Week, Randomized, Double-Blind, Placebo-Controlled Clinical Trial
PubMed ID: 39683431
Randomized trial in older adults showed pasteurized A. muciniphila improved leg muscle strength and follistatin—directly relevant to healthy aging and sarcopenia prevention.
Similar by evidence
Supplements the same benefits carry qualifying findings for — a fact about the evidence graph, not a recommendation to swap.
Products with Akkermansia muciniphila
Search all322 products whose verified label declares Akkermansia muciniphila — not every bottle that mentions it in a title.
Being studied right now
Recruiting clinical trials registered on ClinicalTrials.gov. A trial in progress has no result yet — this is what the field is asking, not what it found.