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Spirulina

18 benefits mapped to clinical evidence across supplements.

Dose per serving from products

590 products in our catalogue print how much Spirulina a serving holds.

Most common: 2.5 g to 5 g, 27% of 590 products.

Dose per servingProducts
10 mg or less
15
10 mg to 25 mg
22
25 mg to 50 mg
40
50 mg to 100 mg
42
100 mg to 250 mg
66
250 mg to 500 mg
126
500 mg to 1 g
79
1 g to 2.5 g
39
2.5 g to 5 g
157
over 5 g
4

Dose per serving from research

54 study groups in 45 studies say how much Spirulina participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 500 mg to 1 g, 28% of 54 study groups.

Daily doseStudy groups
500 mg or less
2
500 mg to 1 g
15
1 g to 2.5 g
12
2.5 g to 5 g
8
5 g to 10 g
13
10 g to 25 g
3
over 25 g
1

See every study group

Benefit Evidence

Inflammation
Moderate

↓ IL-6, hs-CRP

↓ IL-4, 32%

728 people

↓ weight/fat

↓ appetite/inflammation

932 people
Heart health
Moderate

Blood pressure, stiffness

Lipids, glucose, inflammation

701 people
Vitality
Moderate

Metabolic health: −1.43% HbA1c

Weight/lipid gains: −41 mg/dL TC

Immune/growth: +9 pp walking

1,364 people
Cholesterol
Moderate

TC, LDL ↓

TG, HDL ↑

597 people

Protein synthesis +AA

Micronutrient/child growth

1,421 people

Inflammation ↓; IL-4/IL-6

Immune balance ↑; IFN-γ

865 people
Antioxidant
Moderate

Antioxidant boost +56µM

Oxidative stress ↓

321 people

Liver markers improved

Arsenic detoxification +47.1%

187 people

Cognition +0.3 MMSE

Fatigue, learning

Development +0.7 motor

507 people

Iron↓, Ca/Mg↔

Hb↑, anemia↓

279 people

Hepatic mood/QoL +23.7

Stress/sleep mood lift

146 people

Energy/fatigue: +VO2, time-to-fatigue

Energy/fatigue: ↓MDA, ↑SOD/GSH

Energy/fatigue: +32% TE

112 people

Melanosis/keratosis improved; hair As -47.1%

Lesions and burning improved

101 people

Recovery: less damage

+32% fatigue time

76 people

Rhinitis symptoms ↓

IL-4 -32%

53 people

Antioxidant/anti-inflammatory recovery

Fatigue/endurance +8.9%

52 people

Rebound dyspepsia ↓55.6%

Reflux unchanged

43 people

Research sources

Inflammation (10)
  1. Spirulina maxima improves insulin sensitivity, lipid profile, and total antioxidant status in obese patients with well-treated hypertension: a randomized double-blind placebo-controlled study

    PubMed ID: 28617537

    Obese hypertensive RCT recorded decreased inflammatory markers (e.g., IL‑6) alongside metabolic benefits.

  2. A randomized double-blind, placebo-controlled study to establish the effects of spirulina in elderly Koreans

    PubMed ID: 18714150

    Elderly RCT showed decreased IL‑6 (pro‑inflammatory) versus placebo.

  3. Effects of Spirulina supplementation in patients with ulcerative colitis: a double-blind, placebo-controlled randomized trial

    PubMed ID: 38424572

    UC RCT improved antioxidant markers and some QoL/stool outcomes; inflammatory biomarkers largely unchanged but antioxidant changes suggest anti‑inflammatory potential.

  4. Effect of high-dose Spirulina supplementation on hospitalized adults with COVID-19: a randomized controlled trial

    PubMed ID: 38655258

    Hospitalized COVID trial (open‑label) reported decreased IL‑6 and favorable cytokine shifts (↑IFN‑γ).

  5. The effects of spirulina intake on clinical and metabolic parameters in Alzheimer's disease: A randomized, double-blind, controlled trial

    PubMed ID: 36861852

    Alzheimer's RCT showed reduced hs‑CRP and modest cognitive benefit, indicating decreased systemic inflammation.

  6. Antioxidant Efficacy of a Spirulina Liquid Extract on Oxidative Stress Status and Metabolic Disturbances in Subjects with Metabolic Syndrome

    PubMed ID: 35877734

    Phycocyanin-rich extract lowered oxidative stress and improved lipids; oxidative stress reductions often accompany lower inflammation.

  7. Efficacy of Spirulina 500 mg vs Triamcinolone Acetonide 0.1% for the Treatment of Oral Lichen Planus: A Randomized Clinical Trial

    PubMed ID: 35986466

    Adjunctive spirulina with steroids in oral lichen planus reduced lesion size and pain — clinically meaningful anti-inflammatory effect.

  8. Clinical comparison of the efficacy of spirulina platensis and cetirizine for treatment of allergic rhinitis

    PubMed ID: 32773785

    Allergic rhinitis RCT reduced IL‑4 and nasal inflammation markers — direct inflammatory cytokine reduction.

  9. Spirulina platensis effectively ameliorates anthropometric measurements and obesity-related metabolic disorders in obese or overweight healthy individuals: A randomized controlled trial

    PubMed ID: 30219433

    In calorie-restricted overweight/obese adults, spirulina lowered hs‑CRP and appetite, indicating anti-inflammatory effects.

  10. Effects of spirulina (Arthrospira) platensis supplementation on inflammation, physical and mental quality of life, and anthropometric measures in patients with relapsing-remitting multiple sclerosis (RRMS): a triple-blinded, randomized, placebo-controlled trial

    PubMed ID: 40877830

    Triple‑blind RCT in RRMS demonstrated robust reductions in proinflammatory cytokines IL‑1β and IL‑6.

Weight management (9)
  1. Spirulina supplementation and circuit resistance training (CRT) reduce serum asprosin and appetite and improve energy balance in men with obesity and overweight

    PubMed ID: 39259404

    Randomized trial in overweight men found spirulina (with circuit training) reduced calorie intake, lowered asprosin, and produced weight loss.

  2. Spirulina supplementation during gradual weight loss in competitive wrestlers

    PubMed ID: 33715648

    Wrestlers lost more fat and fat mass with spirulina during a weight-loss program — relevant athletic weight management context.

  3. Nutrition rehabilitation of undernourished children utilizing Spiruline and Misola

    PubMed ID: 16430775

    Large programmatic RCT in undernourished children: adding spirulina increased weight gain (context: nutritional rehabilitation).

  4. Effects of spirulina consumption on body weight, blood pressure, and endothelial function in overweight hypertensive Caucasians: a double-blind, placebo-controlled, randomized trial

    PubMed ID: 26813468

    Overweight hypertensive adults lost weight and BMI fell significantly after 3 months of 2 g/day spirulina.

  5. The effects of Spirulina Platensis on anthropometric indices, appetite, lipid profile and serum vascular endothelial growth factor (VEGF) in obese individuals: a randomized double blinded placebo controlled trial

    PubMed ID: 28431534

    1 g/day for 12 weeks in obese adults produced modest but statistically significant weight and appetite reductions.

  6. Effect of Arthrospira (Spirulina) maxima Supplementation and a Systematic Physical Exercise Program on the Body Composition and Cardiorespiratory Fitness of Overweight or Obese Subjects: A Double-Blind, Randomized, and Crossover Controlled Trial

    PubMed ID: 30275428

    4.5 g/day for 6 weeks reduced weight and body fat in overweight/obese men (additive with exercise) — robust short-term effect.

  7. Spirulina platensis effectively ameliorates anthropometric measurements and obesity-related metabolic disorders in obese or overweight healthy individuals: A randomized controlled trial

    PubMed ID: 30219433

    12-week trial during calorie restriction showed greater weight, waist and body-fat reductions with spirulina vs placebo.

  8. Hypolipidemic Effect of Arthrospira (Spirulina) maxima Supplementation and a Systematic Physical Exercise Program in Overweight and Obese Men: A Double-Blind, Randomized, and Crossover Controlled Trial

    PubMed ID: 31067674

    4.5 g/day trial showed modest BMI reductions along with lipid improvements in overweight/obese men.

  9. Impact of a 12-week High-Intensity Interval Training With Spirulina Supplementation on Insulin Resistance-Mediated by Apo-A, -B, and -J in Men With Obesity HIIT With Spirulina on Apolipoproteins

    PubMed ID: 40123054

    HIIT + spirulina study showed weight loss and improved metabolic markers, though exercise was a major driver.

Heart health (10)
  1. Benefits of Dietary Supplementation with Specific Silicon-Enriched Spirulina on Arterial Function in Healthy Elderly Individuals: A Randomized, Placebo-Controlled Trial

    PubMed ID: 40077730

    Silicon‑enriched spirulina RCT reduced aortic pulse wave velocity and systolic BP in older adults with elevated baseline aPWV/SBP—robust CV surrogate improvements in higher‑risk subgroup.

  2. Impact of a 12-week High-Intensity Interval Training With Spirulina Supplementation on Insulin Resistance-Mediated by Apo-A, -B, and -J in Men With Obesity HIIT With Spirulina on Apolipoproteins

    PubMed ID: 40123054

    HIIT + spirulina improved apolipoprotein profile (Apo‑A/Apo‑B) and metabolic risk factors, though exercise contributed significantly.

  3. A randomized, double-blind placebo-controlled add-on trial to assess the efficacy, safety, and anti-atherogenic effect of spirulina platensis in patients with inadequately controlled type 2 diabetes mellitus

    PubMed ID: 36598187

    Add‑on trial produced meaningful reductions in TC/LDL/TG and HbA1c, all favorable for cardiovascular risk.

  4. Antioxidant Efficacy of a Spirulina Liquid Extract on Oxidative Stress Status and Metabolic Disturbances in Subjects with Metabolic Syndrome

    PubMed ID: 35877734

    Reduced oxidative stress and improved HDL/TG in metabolic-syndrome subjects support cardiovascular risk reduction.

  5. Antihypertensive and antihyperlipemic of spirulina (Arthrospira platensis) sauce on patients with hypertension: A randomized triple-blind placebo-controlled clinical trial

    PubMed ID: 34542204

    Triple-blind RCT using spirulina-containing salad dressing lowered systolic/diastolic BP and improved lipids in hypertensive patients.

  6. Hypolipidemic Effect of Arthrospira (Spirulina) maxima Supplementation and a Systematic Physical Exercise Program in Overweight and Obese Men: A Double-Blind, Randomized, and Crossover Controlled Trial

    PubMed ID: 31067674

    Sizeable drops in TC and LDL-C in overweight/obese men support improved cardiometabolic profile.

  7. Spirulina maxima improves insulin sensitivity, lipid profile, and total antioxidant status in obese patients with well-treated hypertension: a randomized double-blind placebo-controlled study

    PubMed ID: 28617537

    Improvements in LDL-C, insulin sensitivity and TAS in obese hypertensive patients indicate cardiovascular risk benefits.

  8. Effects of spirulina consumption on body weight, blood pressure, and endothelial function in overweight hypertensive Caucasians: a double-blind, placebo-controlled, randomized trial

    PubMed ID: 26813468

    Overweight hypertensives had significant systolic BP reduction and improved arterial stiffness after 3 months.

  9. Effects of Spirulina platensis supplementation on lipid profile in HIV-infected antiretroviral naïve patients in Yaounde-Cameroon: a randomized trial study

    PubMed ID: 25496727

    Major improvements in atherogenic lipids in a large HIV cohort support cardiovascular risk reduction.

  10. A randomized double-blind, placebo-controlled study to establish the effects of spirulina in elderly Koreans

    PubMed ID: 18714150

    Cholesterol reductions in elderly trial support CV health to a moderate extent.

Vitality (7)
  1. Spirulina platensis versus silymarin in the treatment of chronic hepatitis C virus infection. A pilot randomized, comparative clinical trial

    PubMed ID: 22497849

    Chronic hepatitis C pilot: spirulina improved ALT and quality‑of‑life measures vs silymarin.

  2. The effect of Spirulina platensis versus soybean on insulin resistance in HIV-infected patients: a randomized pilot study

    PubMed ID: 22254118

    In HIV patients, spirulina improved insulin sensitivity and preserved lean mass—markers of metabolic/functional vitality.

  3. Nutrition rehabilitation of undernourished children utilizing Spiruline and Misola

    PubMed ID: 16430775

    Improved anthropometrics and nutritional status in undernourished children when spirulina was added.

  4. Effects of Spirulina platensis supplementation on lipid profile in HIV-infected antiretroviral naïve patients in Yaounde-Cameroon: a randomized trial study

    PubMed ID: 25496727

    Large HIV trial showed major lipid improvements that could contribute to overall health.

  5. Effects of spirulina consumption on body weight, blood pressure, and endothelial function in overweight hypertensive Caucasians: a double-blind, placebo-controlled, randomized trial

    PubMed ID: 26813468

    Weight loss and lower blood pressure in overweight hypertensives support general health/vitality.

  6. Multiple micronutrient supplementation using spirulina platensis and infant growth, morbidity, and motor development: Evidence from a randomized trial in Zambia

    PubMed ID: 30759117

    In infants, Spirulina-fortified porridge reduced respiratory morbidity and improved motor milestone acquisition — benefits to early-life vitality/development.

  7. A randomized, double-blind placebo-controlled add-on trial to assess the efficacy, safety, and anti-atherogenic effect of spirulina platensis in patients with inadequately controlled type 2 diabetes mellitus

    PubMed ID: 36598187

    Add‑on to metformin improved HbA1c and lipids substantially, outcomes that support broader health and vitality.

Cholesterol (9)
  1. Hypolipidemic Effect of Arthrospira (Spirulina) maxima Supplementation and a Systematic Physical Exercise Program in Overweight and Obese Men: A Double-Blind, Randomized, and Crossover Controlled Trial

    PubMed ID: 31067674

    4.5 g/day for 6 weeks produced sizeable, consistent reductions in total and LDL cholesterol in overweight/obese men (RCT crossover).

  2. Antihypertensive and antihyperlipemic of spirulina (Arthrospira platensis) sauce on patients with hypertension: A randomized triple-blind placebo-controlled clinical trial

    PubMed ID: 34542204

    Functional-food RCT in hypertensive patients lowered total and LDL cholesterol and triglycerides over 8 weeks.

  3. Antioxidant Efficacy of a Spirulina Liquid Extract on Oxidative Stress Status and Metabolic Disturbances in Subjects with Metabolic Syndrome

    PubMed ID: 35877734

    Phycocyanin-rich extract RCT increased HDL and decreased triglycerides in metabolic-syndrome subjects.

  4. A randomized, double-blind placebo-controlled add-on trial to assess the efficacy, safety, and anti-atherogenic effect of spirulina platensis in patients with inadequately controlled type 2 diabetes mellitus

    PubMed ID: 36598187

    Add‑on to metformin produced large, significant reductions in TC, LDL‑C and TG with a small increase in HDL‑C over 3 months.

  5. Impact of a 12-week High-Intensity Interval Training With Spirulina Supplementation on Insulin Resistance-Mediated by Apo-A, -B, and -J in Men With Obesity HIIT With Spirulina on Apolipoproteins

    PubMed ID: 40123054

    HIIT + spirulina improved apolipoprotein profile (↑Apo‑A, ↓Apo‑B) though exercise was a major contributor.

  6. The effects of Spirulina Platensis on anthropometric indices, appetite, lipid profile and serum vascular endothelial growth factor (VEGF) in obese individuals: a randomized double blinded placebo controlled trial

    PubMed ID: 28431534

    1 g/day for 12 weeks reduced total cholesterol modestly in obese adults.

  7. Effects of Spirulina platensis supplementation on lipid profile in HIV-infected antiretroviral naïve patients in Yaounde-Cameroon: a randomized trial study

    PubMed ID: 25496727

    Large randomized trial in ART‑naïve HIV patients showed dramatic reductions in TC/LDL and large HDL increases with 10 g/day spirulina.

  8. A randomized double-blind, placebo-controlled study to establish the effects of spirulina in elderly Koreans

    PubMed ID: 18714150

    Elderly RCT observed significant total cholesterol reductions vs placebo (sex‑specific effects reported).

  9. Spirulina maxima improves insulin sensitivity, lipid profile, and total antioxidant status in obese patients with well-treated hypertension: a randomized double-blind placebo-controlled study

    PubMed ID: 28617537

    Obese hypertensive RCT reported significant LDL-C decreases along with metabolic improvements.

Nutrition source (6)
  1. Algae Ingestion Increases Resting and Exercised Myofibrillar Protein Synthesis Rates to a Similar Extent as Mycoprotein in Young Adults

    PubMed ID: 37716611

    Single bolus study confirms spirulina provides bioavailable amino acids and stimulates MyoPS, supporting nutrient richness (protein).

  2. Nutrition rehabilitation of undernourished children utilizing Spiruline and Misola

    PubMed ID: 16430775

    Programmatic RCT showed spirulina (10 g/day) added to meals improved weight and z‑score gains in undernourished children—nutritional benefit.

  3. [Selenium deficiency and its dietary correction in patients with irritable bowel syndrome and chronic catarrhal colitis]

    PubMed ID: 17674518

    Spirulina‑based selenium supplement corrected selenium insufficiency in IBS/colitis patients (product was Se‑enriched).

  4. Spirulina as a daily nutritional supplement of young pre-school Cambodian children of deprived settings: a single-blinded, placebo-controlled, cross-over trial

    PubMed ID: 36476193

    2 g/day in preschool children modestly reduced anemia and tended to improve weight — evidence of nutritional benefit in undernourished populations.

  5. [Use of spirulina supplement for nutritional management of HIV-infected patients: study in Bangui, Central African Republic]

    PubMed ID: 19499738

    Large HIV trial reported higher blood protein (protidemia) with spirulina plus food aid, consistent with nutrient supply.

  6. Multiple micronutrient supplementation using spirulina platensis and infant growth, morbidity, and motor development: Evidence from a randomized trial in Zambia

    PubMed ID: 30759117

    Spirulina-fortified porridge provided nutrients that reduced cough and aided motor milestone acquisition in infants — practical nutrient benefit.

Immune support (6)
  1. Effect of high-dose Spirulina supplementation on hospitalized adults with COVID-19: a randomized controlled trial

    PubMed ID: 38655258

    Hospitalized COVID open‑label trial showed increased IFN‑γ, decreased IL‑6 and dramatic clinical improvements (immune‑related), though design limitations exist.

  2. Multiple micronutrient supplementation using spirulina platensis and infant growth, morbidity, and motor development: Evidence from a randomized trial in Zambia

    PubMed ID: 30759117

    Large infant RCT showed reduced cough incidence with Spirulina-fortified porridge, indicating respiratory immune benefits.

  3. Clinical comparison of the efficacy of spirulina platensis and cetirizine for treatment of allergic rhinitis

    PubMed ID: 32773785

    Allergic rhinitis RCT improved nasal symptoms and reduced IL‑4, indicating immune/ allergic modulation.

  4. Effects on Spirulina Supplementation on Immune Cells' Parameters of Elite College Athletes

    PubMed ID: 36297029

    In athletes, 3 g/day maintained leukocyte and monocyte proportions during heavy training — supportive of immune resilience.

  5. Arthrospira Enhances Seroclearance in Patients with Chronic Hepatitis B Receiving Nucleos(t)ide Analogue through Modulation of TNF-α/IFN-γ Profile

    PubMed ID: 35889747

    In hepatitis B patients spirulina increased IFN‑γ and reduced qHBsAg in some groups—direct immune modulation evidence.

  6. A randomized double-blind, placebo-controlled study to establish the effects of spirulina in elderly Koreans

    PubMed ID: 18714150

    Elderly RCT increased IL‑2 and decreased IL‑6, indicating modulation of immune markers.

Antioxidant (5)
  1. Antioxidant Efficacy of a Spirulina Liquid Extract on Oxidative Stress Status and Metabolic Disturbances in Subjects with Metabolic Syndrome

    PubMed ID: 35877734

    Phycocyanin-rich extract RCT lowered urinary isoprostanes (oxidative stress marker) vs placebo in metabolic-syndrome subjects.

  2. Effects of Spirulina supplementation in patients with ulcerative colitis: a double-blind, placebo-controlled randomized trial

    PubMed ID: 38424572

    RCT in ulcerative colitis showed significant increases in total antioxidant capacity and decreased MDA (lipid peroxidation).

  3. Spirulina maxima improves insulin sensitivity, lipid profile, and total antioxidant status in obese patients with well-treated hypertension: a randomized double-blind placebo-controlled study

    PubMed ID: 28617537

    Obese hypertensive RCT reported increased total antioxidant status (TAS) alongside metabolic benefits.

  4. The effect of Arthrospira platensis capsules on CD4 T-cells and antioxidative capacity in a randomized pilot study of adult women infected with human immunodeficiency virus not under HAART in Yaoundé, Cameroon

    PubMed ID: 25057105

    Small trial reported increased total antioxidant capacity (TAOS) with spirulina.

  5. A randomized double-blind, placebo-controlled study to establish the effects of spirulina in elderly Koreans

    PubMed ID: 18714150

    Elderly RCT: improved total antioxidant status and SOD activity vs placebo.

Detoxification (4)
  1. The Effect of Eight Weeks of Aerobic Exercise and Spirulina Supplementation on Some Liver Enzymes, Body Composition, and Cardiorespiratory Fitness in Overweight and Obese Adult Women

    PubMed ID: 40304664

    Spirulina (with/without exercise) led to improvements in ALT/AST in overweight/obese women, indicating improved hepatic markers.

  2. Arthrospira Enhances Seroclearance in Patients with Chronic Hepatitis B Receiving Nucleos(t)ide Analogue through Modulation of TNF-α/IFN-γ Profile

    PubMed ID: 35889747

    In chronic hepatitis B patients spirulina lowered HBsAg (in subgroup), raised IFN‑γ and reduced liver stiffness—consistent with improved liver health/function.

  3. Efficacy of spirulina extract plus zinc in patients of chronic arsenic poisoning: a randomized placebo-controlled study

    PubMed ID: 16615668

    Randomized trial (spirulina + zinc) markedly increased urinary arsenic excretion and improved skin lesions.

  4. Effect of Spirulina maxima Supplementation on Calcium, Magnesium, Iron, and Zinc Status in Obese Patients with Treated Hypertension

    PubMed ID: 26779620

    3‑month RCT showed spirulina lowered serum iron—consistent with an iron‑binding/chelating effect.

Mental clarity (3)
  1. Multiple Micronutrient Supplementation Using Spirulina platensis during the First 1000 Days is Positively Associated with Development in Children under Five Years: A Follow up of A Randomized Trial in Zambia

    PubMed ID: 30934863

    Follow-up of child trial showed persistent improvements in motor and language/personal-social scores — evidence of mental/developmental gains after early supplementation.

  2. The effects of spirulina intake on clinical and metabolic parameters in Alzheimer's disease: A randomized, double-blind, controlled trial

    PubMed ID: 36861852

    12‑week RCT in Alzheimer's patients produced small but statistically significant improvements in MMSE and reductions in hs‑CRP and insulin resistance markers.

  3. The Effects of Spirulina maxima Extract on Memory Improvement in Those with Mild Cognitive Impairment: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial

    PubMed ID: 36145090

    12‑week RCT in older adults with MCI showed significant improvements in visual learning and working memory — direct cognitive benefit.

Nutrient uptake (3)
  1. Spirulina as a daily nutritional supplement of young pre-school Cambodian children of deprived settings: a single-blinded, placebo-controlled, cross-over trial

    PubMed ID: 36476193

    2 g/day in Cambodian preschoolers significantly reduced anemia prevalence — field evidence of improving iron/hemoglobin status.

  2. Effect of Spirulina maxima Supplementation on Calcium, Magnesium, Iron, and Zinc Status in Obese Patients with Treated Hypertension

    PubMed ID: 26779620

    3‑month RCT in obese hypertensives showed a clear and significant decrease in serum iron with spirulina.

  3. The effects of spirulina supplementation on serum iron and ferritin, anemia parameters, and fecal occult blood in adults with ulcerative colitis: A randomized, double-blinded, placebo-controlled trial

    PubMed ID: 37739734

    RCT in ulcerative colitis found spirulina 1 g/day improved serum iron and MCV and prevented declines in RBC/hematocrit vs placebo.

Mood balance (2)
  1. The effects of spirulina (Arthrospira platensis) supplementation on anthropometric indices, blood pressure, sleep quality, mental health, fatigue status and quality of life in patients with ulcerative colitis: A randomised, double-blinded, placebo-controlled trial

    PubMed ID: 34107141

    In ulcerative colitis patients, 8 weeks of 1 g/day spirulina modestly reduced stress and improved quality of life — mood-related outcomes.

  2. Spirulina platensis versus silymarin in the treatment of chronic hepatitis C virus infection. A pilot randomized, comparative clinical trial

    PubMed ID: 22497849

    Chronic hepatitis C trial reported improved quality‑of‑life and sexual function scores with spirulina (mood/psychosocial benefit).

Energy & Fatigue (2)
  1. Spirulina supplementation and circuit resistance training (CRT) reduce serum asprosin and appetite and improve energy balance in men with obesity and overweight

    PubMed ID: 39259404

    In overweight men, spirulina was associated with increased reported energy and increased energy expenditure alongside appetite/hormone changes.

  2. Effect of Arthrospira (Spirulina) maxima Supplementation and a Systematic Physical Exercise Program on the Body Composition and Cardiorespiratory Fitness of Overweight or Obese Subjects: A Double-Blind, Randomized, and Crossover Controlled Trial

    PubMed ID: 30275428

    Six-week trial (4.5 g/day) improved VO2max and time-to-fatigue in overweight/obese men — supports increased functional energy/endurance.

Skin appearance (2)
  1. Efficacy of Spirulina 500 mg vs Triamcinolone Acetonide 0.1% for the Treatment of Oral Lichen Planus: A Randomized Clinical Trial

    PubMed ID: 35986466

    Adjunctive spirulina reduced lesion size and pain in oral lichen planus — shows anti-inflammatory/dermatologic benefit in mucocutaneous disease.

  2. Efficacy of spirulina extract plus zinc in patients of chronic arsenic poisoning: a randomized placebo-controlled study

    PubMed ID: 16615668

    Skin lesion scores (melanosis/keratosis) improved in arsenic‑poisoned patients receiving spirulina+zinc.

Exercise recovery (2)
  1. Algae Ingestion Increases Resting and Exercised Myofibrillar Protein Synthesis Rates to a Similar Extent as Mycoprotein in Young Adults

    PubMed ID: 37716611

    Tracer‑based RCT showed a single spirulina bolus raised plasma amino acids and stimulated myofibrillar protein synthesis at rest and after exercise similar to a high‑quality fungal protein.

  2. Spirulina supplementation during gradual weight loss in competitive wrestlers

    PubMed ID: 33715648

    Wrestlers lost more fat and had decreased myostatin during weight-loss period, suggesting favorable muscle-related signaling.

Allergy relief (1)
  1. Clinical comparison of the efficacy of spirulina platensis and cetirizine for treatment of allergic rhinitis

    PubMed ID: 32773785

    Randomized trial in allergic rhinitis showed marked clinical symptom improvements (rhinorrhea, nasal obstruction) and IL‑4 reductions with 2 g/day for 2 months.

Endurance (1)
  1. Effect of Arthrospira (Spirulina) maxima Supplementation and a Systematic Physical Exercise Program on the Body Composition and Cardiorespiratory Fitness of Overweight or Obese Subjects: A Double-Blind, Randomized, and Crossover Controlled Trial

    PubMed ID: 30275428

    6-week supplementation improved VO2max and time-to-fatigue in overweight/obese men, particularly with exercise.

Digestive support (1)
  1. Spirulina Platensis Attenuates Rebound Dyspeptic Symptoms After Proton Pump Inhibitors' Discontinuation: Phase 2 Placebo-controlled Trial

    PubMed ID: 38401078

    Phase 2 RCT showed spirulina reduced the likelihood of rebound dyspepsia after stopping PPIs vs placebo.

Similar by evidence

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Products with Spirulina

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Being studied right now

Recruiting clinical trials registered on ClinicalTrials.gov. A trial in progress has no result yet — this is what the field is asking, not what it found.