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Astaxanthin

17 benefits mapped to clinical evidence across supplements.

Dose per serving from products

1,670 products in our catalogue print how much Astaxanthin a serving holds.

Most common: 10 mg to 25 mg, 26% of 1,670 products.

Dose per servingProducts
25 mcg or less
70
25 mcg to 50 mcg
102
50 mcg to 100 mcg
118
100 mcg to 250 mcg
143
250 mcg to 500 mcg
108
500 mcg to 1 mg
118
1 mg to 2.5 mg
136
2.5 mg to 5 mg
245
5 mg to 10 mg
120
10 mg to 25 mg
433
over 25 mg
77

Dose per serving from research

59 study groups in 45 studies say how much Astaxanthin participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 10 mg to 25 mg, 37% of 59 study groups.

Daily doseStudy groups
500 mcg or less
2
500 mcg to 1 mg
2
1 mg to 2.5 mg
2
2.5 mg to 5 mg
9
5 mg to 10 mg
20
10 mg to 25 mg
22
over 25 mg
2

See every study group

Commonly used together

13 of 59 study groups took Astaxanthin with something else. Shown: what 3 or more different studies gave.

What was given together, not what works together.

Taken withStudy groups
Lutein
3
Zeaxanthin
3

Benefit Evidence

Lower MDA/TAC +

+SOD, -MDA

Lower CK/AST +

818 people
Inflammation
Moderate

↓IL-6/TNF-α

↓CRP/ESR

483 people

Anti-inflammatory, antioxidant support

+oocyte outcomes

Cytokines/oxidative stress -

318 people
Metabolism
Moderate

Lipids/adiponectin

+HDL -TG

Glucose/insulin resistance

307 people
Fertility
Moderate

Oxidative stress↓, oocytes↑

Inflammation↓, embryos↑

286 people

Vision: +4.6 VA

Skin: wrinkles/elasticity

Cognition/Oxidative: -21s, -65%

412 people
Heart health
Moderate

Lipids/oxidative stress

Glucose/endothelial

277 people
Vitality
Moderate

Antioxidant + fertility

+pregnancy, -ROS

Exercise performance + metabolism

194 people

Fatigue ↓, +13

Recovery/efficiency ↑, +1.2%

184 people
Endurance
Moderate

Faster, +power

Better fat use

176 people
Skin health
Moderate

Wrinkles/elasticity/hydration improved

UV resistance +5 mJ/cm2

176 people
Eye health
Moderate

Retinal function + blood flow

Visual acuity + fatigue

266 people

Pain/function, −20.8 mm

Inflammation, CRP↓

222 people

Wrinkles, elasticity +moisture

Barrier + collagen genes

144 people

Processing speed + cognition

Fatigue recovery - oxidative stress

169 people

Choroidal flow +

Endothelial/metabolic +

76 people

Less muscle damage

Better fuel use

Anti‑inflammatory +VANT

72 people

Research sources

Antioxidant (16)
  1. The Beneficial Effects of Astaxanthin on Glucose Metabolism and Modified Low-Density Lipoprotein in Healthy Volunteers and Subjects with Prediabetes

    PubMed ID: 34959932

    12 mg/day reduced oxidized-LDL and improved related markers over 12 weeks (human trial with metabolic/endothelial endpoints).

  2. Astaxanthin ameliorates inflammation, oxidative stress, and reproductive outcomes in endometriosis patients undergoing assisted reproduction: A randomized, triple-blind placebo-controlled clinical trial

    PubMed ID: 37020589

    12-week astaxanthin increased TAC and SOD and decreased MDA in women with endometriosis (robust human biomarker changes).

  3. Astaxanthin supplementation impact on insulin resistance, lipid profile, blood pressure, and oxidative stress in polycystic ovary syndrome patients: A triple-blind randomized clinical trial

    PubMed ID: 37874168

    Triple-blind RCT in PCOS showed increased TAC and decreased MDA with astaxanthin alone.

  4. Astaxanthin treatment ameliorates ER stress in polycystic ovary syndrome patients: a randomized clinical trial

    PubMed ID: 36854788

    Astaxanthin prior to ART raised follicular TAC and reduced ER-stress markers in a randomized trial.

  5. Randomized clinical trial of astaxanthin supplement on serum inflammatory markers and ER stress-apoptosis gene expression in PBMCs of women with PCOS

    PubMed ID: 39036884

    RCT in PCOS women showed reduced ER-stress and inflammation with concomitant antioxidant biomarker changes in immune cells.

  6. Astaxanthin improves assisted reproductive technology outcomes in poor ovarian responders through alleviating oxidative stress, inflammation, and apoptosis: a randomized clinical trial

    PubMed ID: 39482765

    Triple-blind RCT in poor ovarian responders showed increased SOD/TAC and decreased MDA attributable to astaxanthin.

  7. Impact of astaxanthin on oxidative markers, uric acid, and clinical symptoms in heart failure: a randomized clinical trial

    PubMed ID: 41162864

    Heart-failure RCT reported large increases in SOD/TAC and large decreases in MDA with 20 mg/day astaxanthin.

  8. Redox-sensitive miRNAs and Humanin could mediate effects of exercise and astaxanthin on oxidative stress and inflammation in type 2 diabetes

    PubMed ID: 41249265

    In T2DM, astaxanthin increased total antioxidant capacity and altered redox-sensitive miRNAs in an RCT.

  9. Boosting Antioxidant Defense: The Effect of Astaxantin on Superoxidase Dismutase and Malondialdehyde Reduction in Patients with Head and Neck Cancer Receiving Cisplatin Chemotherapy

    PubMed ID: 39487992

    Trial in head-and-neck cancer patients on cisplatin showed astaxanthin increased SOD and lowered MDA.

  10. Effect of astaxanthin supplementation on muscle damage and oxidative stress markers in elite young soccer players

    PubMed ID: 22828460

    Reduced postexercise muscle‑enzyme release and preservation of total antioxidative status suggest antioxidant protection.

  11. Antioxidant effect of astaxanthin on phospholipid peroxidation in human erythrocytes

    PubMed ID: 21276280

    Dose-dependent incorporation into erythrocytes and reductions in erythrocyte lipid peroxides support antioxidant action.

  12. Protective effects of Haematococcus astaxanthin on oxidative stress in healthy smokers

    PubMed ID: 21883001

    Dose-dependent reductions in isoprostane and improvements in SOD/TAC in heavy smokers show robust antioxidant activity in at‑risk humans.

  13. Effect of astaxanthin supplementation on paraoxonase 1 activities and oxidative stress status in young soccer players

    PubMed ID: 23192897

    In soccer players astaxanthin increased PON1 activity and thiol antioxidants, indicating improved antioxidant defense.

  14. Markers of Hypoxia and Oxidative Stress in Aging Volunteers Ingesting Lycosomal Formulation of Dark Chocolate Containing Astaxanthin

    PubMed ID: 30379308

    Lycosome astaxanthin formulation markedly raised serum ASTX and reduced oxidized LDL/MDA (small human groups but strong biomarker effects).

  15. Improvement of Executive Function after Short-Term Administration of an Antioxidants Mix Containing Bacopa, Lycopene, Astaxanthin and Vitamin B12: The BLAtwelve Study

    PubMed ID: 33375429

    Antioxidant mix containing astaxanthin reduced circulating oxidative-stress marker (8-isoprostane) in older adults with cognitive benefit (multi-ingredient trial).

  16. The antioxidant and anti-inflammatory effects of astaxanthin supplementation on the expression of miR-146a and miR-126 in patients with type 2 diabetes mellitus: A randomised, double-blind, placebo-controlled clinical trial

    PubMed ID: 33445213

    8 mg/day decreased MDA and IL-6 and downregulated pro‑inflammatory miR-146a in T2DM patients (direct oxidative/inflammatory biomarker improvements).

Inflammation (9)
  1. Administration of natural astaxanthin increases serum HDL-cholesterol and adiponectin in subjects with mild hyperlipidemia

    PubMed ID: 19892350

    Increased adiponectin and improved lipids suggest anti‑inflammatory/metabolic modulation in mild hyperlipidemia.

  2. The antioxidant and anti-inflammatory effects of astaxanthin supplementation on the expression of miR-146a and miR-126 in patients with type 2 diabetes mellitus: A randomised, double-blind, placebo-controlled clinical trial

    PubMed ID: 33445213

    8 mg/day lowered IL-6 and MDA and downregulated pro-inflammatory miR-146a in T2DM patients—direct anti-inflammatory biomarker changes.

  3. The Beneficial Effects of Astaxanthin on Glucose Metabolism and Modified Low-Density Lipoprotein in Healthy Volunteers and Subjects with Prediabetes

    PubMed ID: 34959932

    Reduced oxidized-LDL and improved metabolic markers that can lower inflammatory stress, though direct inflammatory cytokine changes were limited.

  4. Astaxanthin ameliorates inflammation, oxidative stress, and reproductive outcomes in endometriosis patients undergoing assisted reproduction: A randomized, triple-blind placebo-controlled clinical trial

    PubMed ID: 37020589

    Astaxanthin reduced multiple pro-inflammatory cytokines (serum and follicular fluid) in endometriosis patients—strong anti-inflammatory signal with clinical reproductive endpoints.

  5. Astaxanthin supplementation impact on insulin resistance, lipid profile, blood pressure, and oxidative stress in polycystic ovary syndrome patients: A triple-blind randomized clinical trial

    PubMed ID: 37874168

    Astaxanthin improved oxidative stress and insulin resistance indices in PCOS, with accompanying anti-inflammatory effects.

  6. A randomized interventional clinical trial assessing the safety and effectiveness of PeaNoc XL tablets in managing joint pain and inflammation in arthritis patients

    PubMed ID: 37767025

    Combination PEA + astaxanthin reduced TNF-α, IL-6, IL-1β and CRP in arthritis patients, indicating anti-inflammatory action though astaxanthin's isolated role unclear.

  7. Randomized clinical trial of astaxanthin supplement on serum inflammatory markers and ER stress-apoptosis gene expression in PBMCs of women with PCOS

    PubMed ID: 39036884

    RCT in PCOS women demonstrated significant reductions in IL-6, IL-18, TNF-α and downregulation of ER-stress/apoptosis genes in immune cells with astaxanthin.

  8. Astaxanthin treatment decreases pro-inflammatory cytokines and improves reproductive outcomes in patients with polycystic ovary syndrome undergoing assisted reproductive technology: A randomized clinical trial

    PubMed ID: 38916710

    PCOS infertile women study showed decreases in systemic IL-6 and IL-1β with astaxanthin.

  9. Astaxanthin supplement improves clinical outcomes, quality of life, and inflammatory factors in patients with rheumatoid arthritis: a randomized clinical trial

    PubMed ID: 40569081

    RA trial reported reductions in ESR/CRP and disease activity with 20 mg/day astaxanthin.

Immune support (6)
  1. The antioxidant and anti-inflammatory effects of astaxanthin supplementation on the expression of miR-146a and miR-126 in patients with type 2 diabetes mellitus: A randomised, double-blind, placebo-controlled clinical trial

    PubMed ID: 33445213

    Decreased IL-6 in T2DM patients, indicating an anti-inflammatory effect relevant to immune balance.

  2. Astaxanthin ameliorates inflammation, oxidative stress, and reproductive outcomes in endometriosis patients undergoing assisted reproduction: A randomized, triple-blind placebo-controlled clinical trial

    PubMed ID: 37020589

    Astaxanthin reduced pro-inflammatory cytokines (IL-1β, TNF-α) in serum and follicular fluid—shows anti-inflammatory/immunomodulatory effects in humans.

  3. Astaxanthin supplementation impact on insulin resistance, lipid profile, blood pressure, and oxidative stress in polycystic ovary syndrome patients: A triple-blind randomized clinical trial

    PubMed ID: 37874168

    PCOS trial showed antioxidant and metabolic improvements and some anti-inflammatory biomarker changes.

  4. A randomized interventional clinical trial assessing the safety and effectiveness of PeaNoc XL tablets in managing joint pain and inflammation in arthritis patients

    PubMed ID: 37767025

    Open-label add-on study (PEA + astaxanthin) reduced proinflammatory cytokines in arthritis patients, though combination limits attribution.

  5. Randomized clinical trial of astaxanthin supplement on serum inflammatory markers and ER stress-apoptosis gene expression in PBMCs of women with PCOS

    PubMed ID: 39036884

    RCT in PCOS showed significant reductions in IL-6, IL-18, TNF-α and downregulation of ER-stress/apoptosis genes in PBMCs with astaxanthin.

  6. Astaxanthin treatment decreases pro-inflammatory cytokines and improves reproductive outcomes in patients with polycystic ovary syndrome undergoing assisted reproductive technology: A randomized clinical trial

    PubMed ID: 38916710

    PCOS infertile women trial showed lowered systemic IL-6 and IL-1β with astaxanthin and improved ART outcomes.

Metabolism (6)
  1. Astaxanthin supplementation enhances metabolic adaptation with aerobic training in the elderly

    PubMed ID: 34110707

    Astaxanthin combined with aerobic training increased fat oxidation and exercise efficiency—favorable for metabolic health over time.

  2. Astaxanthin Supplemented with High-Intensity Functional Training Decreases Adipokines Levels and Cardiovascular Risk Factors in Men with Obesity

    PubMed ID: 36678157

    Obese men undergoing CrossFit plus astaxanthin had greater improvements in body composition, lipids and adipokines than exercise or supplement alone (combined intervention).

  3. Administration of natural astaxanthin increases serum HDL-cholesterol and adiponectin in subjects with mild hyperlipidemia

    PubMed ID: 19892350

    Dose‑response RCT demonstrated decreases in triglycerides and increases in HDL and adiponectin in mild hyperlipidemia — strong metabolic signals.

  4. Astaxanthin improves glucose metabolism and reduces blood pressure in patients with type 2 diabetes mellitus

    PubMed ID: 29384321

    8 mg/day in T2DM raised adiponectin, reduced visceral fat and triglycerides and lowered fructosamine—direct metabolic improvements in patients.

  5. The Beneficial Effects of Astaxanthin on Glucose Metabolism and Modified Low-Density Lipoprotein in Healthy Volunteers and Subjects with Prediabetes

    PubMed ID: 34959932

    12 mg/day for 12 weeks improved 2-h OGTT glucose, lowered 2-h insulin and modestly reduced HbA1c, and improved insulin sensitivity indices in humans.

  6. Astaxanthin supplementation impact on insulin resistance, lipid profile, blood pressure, and oxidative stress in polycystic ovary syndrome patients: A triple-blind randomized clinical trial

    PubMed ID: 37874168

    Triple-blind RCT in PCOS showed significant improvements in fasting glucose, HOMA-IR and insulin with astaxanthin.

Fertility (6)
  1. Astaxanthin treatment ameliorates ER stress in polycystic ovary syndrome patients: a randomized clinical trial

    PubMed ID: 36854788

    Astaxanthin before ART in PCOS reduced ER-stress markers and increased follicular TAC and high-quality embryo rate in a randomized trial.

  2. Astaxanthin improves assisted reproductive technology outcomes in poor ovarian responders through alleviating oxidative stress, inflammation, and apoptosis: a randomized clinical trial

    PubMed ID: 39482765

    Triple-blind RCT in poor ovarian responders showed improved serum antioxidant markers, reduced follicular inflammation/cfDNA, and increased retrieved MII oocytes and high-quality embryos with astaxanthin.

  3. Astaxanthin treatment decreases pro-inflammatory cytokines and improves reproductive outcomes in patients with polycystic ovary syndrome undergoing assisted reproductive technology: A randomized clinical trial

    PubMed ID: 38916710

    PCOS infertile women given astaxanthin had lower systemic inflammation and higher oocyte retrieval and MII counts during ART.

  4. Combined conventional/antioxidant "Astaxanthin" treatment for male infertility: a double blind, randomized trial

    PubMed ID: 16110353

    Randomized trial in men showed reduced sperm oxidative stress, improved motility and a large increase in pregnancy rates with 16 mg/day.

  5. Astaxanthin ameliorates inflammation, oxidative stress, and reproductive outcomes in endometriosis patients undergoing assisted reproduction: A randomized, triple-blind placebo-controlled clinical trial

    PubMed ID: 37020589

    6 mg/day for 12 weeks reduced oxidative/inflammatory markers and increased oocyte yield and high-quality embryos in women with endometriosis undergoing ART.

  6. Astaxanthin supplementation impact on insulin resistance, lipid profile, blood pressure, and oxidative stress in polycystic ovary syndrome patients: A triple-blind randomized clinical trial

    PubMed ID: 37874168

    PCOS trial improved glucose metabolism and oxidative stress markers; relevant to reproductive/metabolic health though ART outcomes less emphasized.

Healthy aging (5)
  1. Improvement of Executive Function after Short-Term Administration of an Antioxidants Mix Containing Bacopa, Lycopene, Astaxanthin and Vitamin B12: The BLAtwelve Study

    PubMed ID: 33375429

    Antioxidant mix including astaxanthin markedly improved executive function and lowered oxidative markers in older adults—supports cognitive aspects of healthy aging (multi-ingredient).

  2. An Examination into the Effects of a Nutraceutical Supplement on Cognition, Stress, Eye Health, and Skin Satisfaction in Adults with Self-Reported Cognitive Complaints: A Randomized, Double-Blind, Placebo-Controlled Trial

    PubMed ID: 38892705

    Nutraceutical trial in adults with subjective memory complaints improved episodic memory and increased BDNF; astaxanthin was part of a combination product.

  3. Carotenoids in Age-related Maculopathy Italian Study (CARMIS): two-year results of a randomized study

    PubMed ID: 22009916

    Long‑term combination supplement (including astaxanthin) stabilized/improved visual function in age‑related maculopathy, supporting age‑related benefit though multi‑nutrient.

  4. Cosmetic benefits of astaxanthin on humans subjects

    PubMed ID: 22428137

    Multiple small trials report improved skin wrinkles and elasticity with oral/topical astaxanthin, relevant to aging appearance.

  5. Markers of Hypoxia and Oxidative Stress in Aging Volunteers Ingesting Lycosomal Formulation of Dark Chocolate Containing Astaxanthin

    PubMed ID: 30379308

    Increased tissue oxygenation and reduced oxidative damage with enhanced astaxanthin bioavailability—mechanisms relevant to aging resilience (small human groups).

Heart health (5)
  1. Impact of astaxanthin on oxidative markers, uric acid, and clinical symptoms in heart failure: a randomized clinical trial

    PubMed ID: 41162864

    Randomized trial in heart-failure patients (20 mg/day) showed large antioxidant improvements and marked symptom (fatigue/dyspnea) reductions, directly relevant to cardiac patients.

  2. The Beneficial Effects of Astaxanthin on Glucose Metabolism and Modified Low-Density Lipoprotein in Healthy Volunteers and Subjects with Prediabetes

    PubMed ID: 34959932

    12 mg/day improved endothelial index (RHI) and reduced oxidized-LDL and post-load insulin/glucose—supports vascular health in humans.

  3. Astaxanthin Supplemented with High-Intensity Functional Training Decreases Adipokines Levels and Cardiovascular Risk Factors in Men with Obesity

    PubMed ID: 36678157

    Obese men on CrossFit + astaxanthin had favorable lipid profile changes (↑HDL, ↓LDL/TC/TG) that benefit cardiovascular risk, though combined intervention complicates attribution.

  4. Markers of Hypoxia and Oxidative Stress in Aging Volunteers Ingesting Lycosomal Formulation of Dark Chocolate Containing Astaxanthin

    PubMed ID: 30379308

    Astaxanthin (especially lycosome formulation) increased tissue oxygen saturation and serum NO while reducing oxidized LDL—mechanistic support for circulation (small groups).

  5. Administration of natural astaxanthin increases serum HDL-cholesterol and adiponectin in subjects with mild hyperlipidemia

    PubMed ID: 19892350

    Dose-ranging RCT showed reductions in triglycerides, increases in HDL and rises in adiponectin in mild hyperlipidemia — relevant to cardiovascular risk/circulation.

Vitality (4)
  1. Combined conventional/antioxidant "Astaxanthin" treatment for male infertility: a double blind, randomized trial

    PubMed ID: 16110353

    Improved sperm function and higher pregnancy rates could reflect improved reproductive vitality in treated men.

  2. The Beneficial Effects of Astaxanthin on Glucose Metabolism and Modified Low-Density Lipoprotein in Healthy Volunteers and Subjects with Prediabetes

    PubMed ID: 34959932

    Improved glucose tolerance, insulin dynamics and endothelial index over 12 weeks—metabolic improvements that can enhance overall vigor.

  3. Astaxanthin supplementation enhances metabolic adaptation with aerobic training in the elderly

    PubMed ID: 34110707

    When combined with aerobic training, astaxanthin increased fat oxidation and efficiency in older adults—boosts functional vitality with exercise.

  4. Impact of astaxanthin on oxidative markers, uric acid, and clinical symptoms in heart failure: a randomized clinical trial

    PubMed ID: 41162864

    Heart-failure RCT reported large reductions in fatigue severity alongside antioxidant improvements, indicating meaningful vitality benefits.

Energy & Fatigue (4)
  1. Markers of Hypoxia and Oxidative Stress in Aging Volunteers Ingesting Lycosomal Formulation of Dark Chocolate Containing Astaxanthin

    PubMed ID: 30379308

    Marked increases in tissue oxygen saturation and serum astaxanthin (lycosome formulation) suggest improved oxygen delivery and cellular energetics (small study).

  2. Effect of astaxanthin supplementation on muscle damage and oxidative stress markers in elite young soccer players

    PubMed ID: 22828460

    Lower postexercise muscle enzymes and preserved antioxidant status in soccer players may reduce fatigue/strain.

  3. Impact of astaxanthin on oxidative markers, uric acid, and clinical symptoms in heart failure: a randomized clinical trial

    PubMed ID: 41162864

    Marked reduction in fatigue severity score in heart-failure patients (20 mg/day) supports reduced fatigue under stressed conditions.

  4. Astaxanthin supplementation enhances metabolic adaptation with aerobic training in the elderly

    PubMed ID: 34110707

    Astaxanthin plus training increased fat oxidation and exercise efficiency in older adults, indicating improved cellular energy utilization during exercise.

Endurance (4)
  1. Astaxanthin supplementation enhances metabolic adaptation with aerobic training in the elderly

    PubMed ID: 34110707

    Enhanced fat oxidation and exercise efficiency with training in older adults implies improved endurance capacity over time (12-week adjunct study).

  2. Effect of astaxanthin supplementation on muscle damage and oxidative stress markers in elite young soccer players

    PubMed ID: 22828460

    Elite soccer players showed less exercise‑related enzyme release and preserved antioxidant status, supportive of endurance resilience.

  3. Astaxanthin Supplemented with High-Intensity Functional Training Decreases Adipokines Levels and Cardiovascular Risk Factors in Men with Obesity

    PubMed ID: 36678157

    Combined intervention improved body composition and muscle-related adipokines; may support endurance when paired with training.

  4. Exploring the Impact of Astaxanthin Supplementation in Conjunction with a 12-Week CrossFit Training Regimen on Selected Adipo-Myokines Levels in Obese Males

    PubMed ID: 39275173

    CrossFit + astaxanthin led to increases in decorin/follistatin and decreases in myostatin/activin/TGF-β1, biomarker changes consistent with improved muscle capacity/endurance.

Skin health (4)
  1. Cosmetic benefits of astaxanthin on humans subjects

    PubMed ID: 22428137

    Small human trials (oral ± topical 6 mg/day) reported improvements in wrinkles, elasticity and hydration measures.

  2. Markers of Hypoxia and Oxidative Stress in Aging Volunteers Ingesting Lycosomal Formulation of Dark Chocolate Containing Astaxanthin

    PubMed ID: 30379308

    Improved oxidative stress markers with enhanced astaxanthin bioavailability may benefit skin health indirectly (small, combined product).

  3. The effectiveness of a standardized rose hip powder, containing seeds and shells of Rosa canina, on cell longevity, skin wrinkles, moisture, and elasticity

    PubMed ID: 26604725

    Small RCT showed astaxanthin improved wrinkle depth, moisture and elasticity over 8 weeks (human randomized double‑blind trial).

  4. Supplementating with dietary astaxanthin combined with collagen hydrolysate improves facial elasticity and decreases matrix metalloproteinase-1 and -12 expression: a comparative study with placebo

    PubMed ID: 24955642

    Combination of astaxanthin (2 mg) with collagen improved facial elasticity and barrier function; attribution to astaxanthin alone limited.

Eye health (3)
  1. Carotenoids in Age-related Maculopathy Italian Study (CARMIS): two-year results of a randomized study

    PubMed ID: 22009916

    A 2‑year lutein/zeaxanthin/astaxanthin-containing supplement stabilized/improved visual function in age‑related maculopathy; astaxanthin attribution uncertain.

  2. Astaxanthin (AstaReal(®)) Improved Acute and Chronic Digital Eye Strain in Children: A Randomized Double-Blind Placebo-Controlled Trial

    PubMed ID: 40014233

    Pediatric RCT (4 mg/day) showed reduced digital eye strain symptoms and improved objective visual measures and stereopsis vs placebo.

  3. Effects of Astaxanthin, Lutein, and Zeaxanthin on Eye-Hand Coordination and Smooth-Pursuit Eye Movement after Visual Display Terminal Operation in Healthy Subjects: A Randomized, Double-Blind Placebo-Controlled Intergroup Trial

    PubMed ID: 36986186

    Astaxanthin + lutein/zeaxanthin improved post-VDT eye–hand coordination and increased MPOD; effects likely aided by combination but clinically relevant improvements seen.

Joint comfort (3)
  1. A Multicenter, Randomized, Double-Blinded, Placebo-Controlled Clinical Trial to Evaluate the Efficacy and Safety of a Krill Oil, Astaxanthin, and Oral Hyaluronic Acid Complex on Joint Health in People with Mild Osteoarthritis

    PubMed ID: 37686801

    12-week randomized trial of a krill-oil/astaxanthin/HA product reduced knee pain and improved function vs placebo, though multi-ingredient limits attribution to astaxanthin alone.

  2. A randomized interventional clinical trial assessing the safety and effectiveness of PeaNoc XL tablets in managing joint pain and inflammation in arthritis patients

    PubMed ID: 37767025

    PEA + astaxanthin added to standard therapy in arthritis reduced inflammatory markers and WOMAC scores; astaxanthin contribution unclear.

  3. Astaxanthin supplement improves clinical outcomes, quality of life, and inflammatory factors in patients with rheumatoid arthritis: a randomized clinical trial

    PubMed ID: 40569081

    20 mg/day astaxanthin for 8 weeks improved disease activity and function in rheumatoid arthritis patients in an RCT.

Skin appearance (3)
  1. The effectiveness of a standardized rose hip powder, containing seeds and shells of Rosa canina, on cell longevity, skin wrinkles, moisture, and elasticity

    PubMed ID: 26604725

    RCT showed significant increases in skin elasticity (Corneometer/elasticity metrics) after 8 weeks of astaxanthin (human trial).

  2. Cosmetic benefits of astaxanthin on humans subjects

    PubMed ID: 22428137

    Clinical trials reported improved skin elasticity with oral/topical astaxanthin.

  3. Supplementating with dietary astaxanthin combined with collagen hydrolysate improves facial elasticity and decreases matrix metalloproteinase-1 and -12 expression: a comparative study with placebo

    PubMed ID: 24955642

    Astaxanthin plus collagen improved skin elasticity and molecular markers versus placebo, though product was combined.

Mental clarity (2)
  1. Improvement of Executive Function after Short-Term Administration of an Antioxidants Mix Containing Bacopa, Lycopene, Astaxanthin and Vitamin B12: The BLAtwelve Study

    PubMed ID: 33375429

    Antioxidant mix including astaxanthin improved executive function tests in older adults, but contribution of astaxanthin alone is uncertain.

  2. An Examination into the Effects of a Nutraceutical Supplement on Cognition, Stress, Eye Health, and Skin Satisfaction in Adults with Self-Reported Cognitive Complaints: A Randomized, Double-Blind, Placebo-Controlled Trial

    PubMed ID: 38892705

    12-week nutraceutical improved episodic memory and increased BDNF in adults with subjective memory complaints; astaxanthin was a component of the blend.

Blood circulation (2)
  1. Markers of Hypoxia and Oxidative Stress in Aging Volunteers Ingesting Lycosomal Formulation of Dark Chocolate Containing Astaxanthin

    PubMed ID: 30379308

    Marked increases in tissue oxygen saturation and serum NO with astaxanthin-containing lycosome chocolate indicate improved microcirculatory/flow parameters (small study).

  2. The Beneficial Effects of Astaxanthin on Glucose Metabolism and Modified Low-Density Lipoprotein in Healthy Volunteers and Subjects with Prediabetes

    PubMed ID: 34959932

    Improved reactive hyperemia index (RHI) after 12 mg/day suggests better endothelial-mediated blood flow (human RCT).

Exercise recovery (2)
  1. Astaxanthin supplementation enhances metabolic adaptation with aerobic training in the elderly

    PubMed ID: 34110707

    With endurance training, astaxanthin increased fat oxidation and efficiency in older adults—may aid recovery/adaptation (human RCT adjunctive to training).

  2. Effect of astaxanthin supplementation on muscle damage and oxidative stress markers in elite young soccer players

    PubMed ID: 22828460

    Soccer players showed reduced postexercise CK/AST and preserved antioxidant status, supporting faster biochemical recovery.

Similar by evidence

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Products with Astaxanthin

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2001 products whose verified label declares Astaxanthin — not every bottle that mentions it in a title.

Being studied right now

Recruiting clinical trials registered on ClinicalTrials.gov. A trial in progress has no result yet — this is what the field is asking, not what it found.