Royal Jelly
12 benefits mapped to clinical evidence across supplements.
Dose per serving from products
163 products in our catalogue print how much Royal Jelly a serving holds.
Most common: 250 mg to 500 mg, 31% of 163 products.
| Dose per serving | Products |
|---|---|
| 2.5 mg or less | 9 |
| 2.5 mg to 5 mg | 11 |
| 5 mg to 10 mg | 8 |
| 10 mg to 25 mg | 4 |
| 25 mg to 50 mg | 24 |
| 50 mg to 100 mg | 17 |
| 100 mg to 250 mg | 30 |
| 250 mg to 500 mg | 50 |
| 500 mg to 1 g | 2 |
| over 1 g | 8 |
Dose per serving from research
15 study groups in 14 studies say how much Royal Jelly participants took a day.
These are the doses the studies gave. They are not a recommendation.
Most common: 500 mg to 1 g, 33% of 15 study groups.
| Daily dose | Study groups |
|---|---|
| 250 mg or less | 1 |
| 250 mg to 500 mg | 2 |
| 500 mg to 1 g | 5 |
| 1 g to 2.5 g | 2 |
| 2.5 g to 5 g | 4 |
| 5 g to 10 g | 1 |
Benefit Evidence
Vascular/inflammation +21%
Lipids/cholesterol -23%
Inflammation/enzymes -19%
Research sources
Hormone balance (3)
- Effect of royal jelly ingestion for six months on healthy volunteers
PubMed ID: 22995464
6-month RJ increased testosterone and T/DHEA-S ratios; indicates endocrine effects in men (or studied population).
- Effect of Royal Jelly on premenstrual syndrome among Iranian medical sciences students: a randomized, triple-blind, placebo-controlled study
PubMed ID: 25146061
Triple-blind RCT: 2 months oral RJ significantly reduced PMS symptom scores — strong clinical endocrine-related symptom benefit.
- Effect of royal jelly on menopausal symptoms: A randomized placebo-controlled clinical trial
PubMed ID: 31470366
1000 mg/day RJ for 8 weeks reduced menopausal symptom scores in a randomized trial — supports hormonal-symptom modulation.
Inflammation (3)
- Apitherapy with Royal Jelly and Green Propolis EPP-AF(®) Improves Cardiovascular Risk Markers in Patients Undergoing Hemodialysis
PubMed ID: 40864045
Hemodialysis RCT found a significant decrease in IL‑6, a key inflammatory cytokine.
- A Randomized, Double-Blind Comparison Study of Royal Jelly to Augment Vascular Endothelial Function in Healthy Volunteers
PubMed ID: 34588374
RJ supplementation reduced hsCRP and improved endothelial function vs placebo in healthy adults (4-week RCT).
- Evaluation of gastric tolerability for long-term use of diclofenac and celecoxib in male albino rats and potential gastroprotective benefits of royal jelly: a randomized controlled trial
PubMed ID: 39680822
Animal study showed reduced gastric ulceration and improved oxidative/inflammatory markers with RJ co‑treatment.
Heart health (3)
- Hypocholesterolemic efficacy of royal jelly in healthy mild hypercholesterolemic adults
PubMed ID: 27937077
Protein-enriched RJ for 3 months lowered total cholesterol and LDL in mildly hypercholesterolemic adults.
- A Randomized, Double-Blind Comparison Study of Royal Jelly to Augment Vascular Endothelial Function in Healthy Volunteers
PubMed ID: 34588374
4-week RCT showed improved endothelial function (Ln-RHI) and reduced hsCRP — direct vascular marker improvement.
- Apitherapy with Royal Jelly and Green Propolis EPP-AF(®) Improves Cardiovascular Risk Markers in Patients Undergoing Hemodialysis
PubMed ID: 40864045
Hemodialysis RCT of RJ+propolis produced a significant reduction in total cholesterol (attributable to combined products).
Antioxidant (3)
- Effects of royal jelly supplementation on glycemic control and oxidative stress factors in type 2 diabetic female: a randomized clinical trial
PubMed ID: 24610413
8-week RJ in T2DM increased SOD/GPx activities and lowered MDA — clear antioxidant-marker changes.
- Impact of royal jelly consumption on oxidative stress, anti-oxidant markers and physical activities of patients with multiple sclerosis: a randomized double-blind placebo-controlled study
PubMed ID: 40824557
Randomized trial in RRMS showed marked increase in SOD and decrease in MDA (strong direct antioxidant biomarker evidence).
- Evaluation of gastric tolerability for long-term use of diclofenac and celecoxib in male albino rats and potential gastroprotective benefits of royal jelly: a randomized controlled trial
PubMed ID: 39680822
In rats, RJ reduced MDA and increased SOD, demonstrating antioxidant effects in animal model.
Skin repair (2)
- Evaluation of gastric tolerability for long-term use of diclofenac and celecoxib in male albino rats and potential gastroprotective benefits of royal jelly: a randomized controlled trial
PubMed ID: 39680822
Animal data show reduced gastric mucosal damage (healing/protection) with RJ co‑treatment.
- The effect of royal jelly on oral mucositis in patients undergoing radiotherapy and chemotherapy
PubMed ID: 24919094
Oral RJ added to standard mouth care shortened healing time of oral mucositis in patients receiving chemo/radiotherapy (controlled study).
Metabolism (2)
- Effect of royal jelly ingestion for six months on healthy volunteers
PubMed ID: 22995464
6-month RJ improved insulinogenic index (IGI) and some glycemic responses.
- Effects of royal jelly supplementation on glycemic control and oxidative stress factors in type 2 diabetic female: a randomized clinical trial
PubMed ID: 24610413
8-week RCT in women with T2DM produced large HbA1c reduction (−1.62%) and improved fasting glucose/insulin markers.
Skin appearance (2)
- Effect of facial application of essence containing royal jelly extract on stratum corneum moisture content: A placebo-controlled, double-blind, parallel-group study
PubMed ID: 35778882
Double-blind split-face trial: topical RJ essence increased cheek stratum corneum moisture over 4 weeks with good tolerability.
- Effect of Protease-Treated Royal Jelly Extract on Facial Wrinkles: A Placebo-Controlled, Double-Blind, Parallel-Group Study
PubMed ID: 41134061
Topical protease‑treated RJ cream reduced wrinkle depth and increased skin hydration and dermal thickness in an RCT.
Endurance (1)
- Effects of protease-treated royal jelly on muscle strength in elderly nursing home residents: A randomized, double-blind, placebo-controlled, dose-response study
PubMed ID: 28900247
One-year pRJ attenuated handgrip strength decline in elderly (dose-dependent), implying preserved muscular function/endurance.
Mood balance (1)
- Effect of Royal Jelly on premenstrual syndrome among Iranian medical sciences students: a randomized, triple-blind, placebo-controlled study
PubMed ID: 25146061
PMS score reductions likely include mood-symptom improvements; strong RCT evidence for symptom relief.
Bone health (1)
- Effects of royal jelly on bone metabolism in postmenopausal women: a randomized, controlled study
PubMed ID: 32880201
6-month RCT in early postmenopausal women attenuated femoral BMD decline and preserved bone formation marker (P1NP).
Healthy aging (1)
- Effect of Protease-Treated Royal Jelly Extract on Facial Wrinkles: A Placebo-Controlled, Double-Blind, Parallel-Group Study
PubMed ID: 41134061
Topical RJ produced statistically significant reductions in wrinkle depth and improved skin hydration/thickness versus placebo.
Digestive support (1)
- Evaluation of gastric tolerability for long-term use of diclofenac and celecoxib in male albino rats and potential gastroprotective benefits of royal jelly: a randomized controlled trial
PubMed ID: 39680822
Rat study: RJ co‑treatment reduced diclofenac/celecoxib‑induced stomach ulcer damage, indicating gastroprotective effects.
Similar by evidence
Supplements the same benefits carry qualifying findings for — a fact about the evidence graph, not a recommendation to swap.
Products with Royal Jelly
Search all248 products whose verified label declares Royal Jelly — not every bottle that mentions it in a title.
Being studied right now
Recruiting clinical trials registered on ClinicalTrials.gov. A trial in progress has no result yet — this is what the field is asking, not what it found.