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Perilla Oil

7 benefits mapped to clinical evidence across supplements.

Dose per serving from products

24 products in our catalogue print how much Perilla Oil a serving holds.

Most common: 50 mg to 100 mg, 42% of 24 products.

Dose per servingProducts
25 mg to 50 mg
3
50 mg to 100 mg
10
100 mg to 250 mg
5
250 mg to 500 mg
5
over 500 mg
1

Dose per serving from research

6 study groups in 5 studies say how much Perilla Oil participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 2.5 g to 5 g, 50% of 6 study groups.

Daily doseStudy groups
1 g to 2.5 g
1
2.5 g to 5 g
3
5 g to 10 g
2

See every study group

Benefit Evidence

Cholesterol
Moderate

LDL-C ↓, TC ↓

TG ↓, HDL-C ↑

488 people
Heart health
Moderate

Lipids↓, HDL↑

Inflammation↓

488 people

Cognition + BDNF

Depression risk -9.6%

149 people

Cognition + BDNF

Bone density +5%

101 people

Lower glucose spikes

−0.67 mmol/L FBG

150 people

EPDS prevalence ↓9.6%

ALA levels → lower distress

100 people

Cognition/antioxidants ↑

ω-3/BDNF ↑

49 people

Research sources

Cholesterol (3)
  1. Outcomes of Perilla Seed Oil as an Additional Neuroprotective Therapy in Patients with Mild to Moderate Dementia: A Randomized Control Trial

    PubMed ID: 30543172

    Perilla seed oil significantly lowered total and LDL cholesterol in a randomized trial—direct evidence for cholesterol-lowering.

  2. Effects of marine-derived and plant-derived omega-3 polyunsaturated fatty acids on erythrocyte fatty acid composition in type 2 diabetic patients

    PubMed ID: 35144649

    Perilla supplementation in T2DM lowered LDL‑C and modified erythrocyte fatty‑acid composition—supports cholesterol/lipid balance.

  3. [Effects of ω-3 polyunsaturated fatty acids from different sources on glucolipid metabolism in type 2 diabetic patients with dyslipidemia]

    PubMed ID: 31177752

    Perilla oil lowered LDL‑C and ApoB in T2DM patients compared with other ω‑3 sources—strong comparative clinical evidence.

Heart health (3)
  1. Outcomes of Perilla Seed Oil as an Additional Neuroprotective Therapy in Patients with Mild to Moderate Dementia: A Randomized Control Trial

    PubMed ID: 30543172

    Large randomized dementia trial found perilla seed oil significantly lowered total and LDL cholesterol—clinically relevant heart/dyslipidemia benefit.

  2. [Effects of ω-3 polyunsaturated fatty acids from different sources on glucolipid metabolism in type 2 diabetic patients with dyslipidemia]

    PubMed ID: 31177752

    Well‑conducted trial in T2DM showed perilla oil specifically lowered LDL‑C and ApoB versus other ω‑3 sources—strong evidence for lipid/heart support.

  3. Effects of marine-derived and plant-derived omega-3 polyunsaturated fatty acids on erythrocyte fatty acid composition in type 2 diabetic patients

    PubMed ID: 35144649

    In 150 T2DM patients, perilla lowered fasting glucose and modestly reduced LDL‑C—beneficial cardiometabolic effects.

Brain health (2)
  1. Perilla seed oil in combination with nobiletin-rich ponkan powder enhances cognitive function in healthy elderly Japanese individuals: a possible supplement for brain health in the elderly

    PubMed ID: 35171190

    12‑month study in elderly: perilla + nobiletin improved cognitive index, increased RBC ω‑3 and serum BDNF—solid evidence for cognitive/brain benefit when combined with nobiletin.

  2. Effects of Varied Omega-3 Fatty Acid Supplementation on Postpartum Mental Health and the Association between Prenatal Erythrocyte Omega-3 Fatty Acid Levels and Postpartum Mental Health

    PubMed ID: 37892462

    Perilla supplementation in pregnancy reduced postpartum depressive symptoms and higher erythrocyte ALA was associated with lower distress—supports perilla's brain/mood relevance.

Healthy aging (2)
  1. Perilla seed oil improves bone health by inhibiting bone resorption in healthy Japanese adults: A 12-month, randomized, double-blind, placebo-controlled trial

    PubMed ID: 36637040

    12‑month randomized trial showed increased calcaneal bone density surrogate and reduced bone resorption marker—meaningful for aging-related bone loss prevention.

  2. Perilla seed oil in combination with nobiletin-rich ponkan powder enhances cognitive function in healthy elderly Japanese individuals: a possible supplement for brain health in the elderly

    PubMed ID: 35171190

    12‑month trial in elderly: perilla + nobiletin improved global cognitive index, increased RBC ω‑3 and BDNF, and improved antioxidant potential—supports healthy cognitive aging when combined with nobiletin.

Energy & Fatigue (1)
  1. Effects of marine-derived and plant-derived omega-3 polyunsaturated fatty acids on erythrocyte fatty acid composition in type 2 diabetic patients

    PubMed ID: 35144649

    Lower fasting glucose in T2DM after 6 months of perilla suggests improved metabolic/energetic regulation.

Mood balance (1)
  1. Effects of Varied Omega-3 Fatty Acid Supplementation on Postpartum Mental Health and the Association between Prenatal Erythrocyte Omega-3 Fatty Acid Levels and Postpartum Mental Health

    PubMed ID: 37892462

    Randomized perilla supplementation in pregnancy reduced postpartum depressive symptoms and higher maternal ALA associated with lower distress—strong, clinically relevant mood signal.

Cell health (1)
  1. Perilla seed oil in combination with nobiletin-rich ponkan powder enhances cognitive function in healthy elderly Japanese individuals: a possible supplement for brain health in the elderly

    PubMed ID: 35171190

    Perilla + nobiletin improved antioxidant potential and raised RBC ω‑3 and BDNF—supports cellular protection/antioxidant defenses.

Similar by evidence

Supplements the same benefits carry qualifying findings for — a fact about the evidence graph, not a recommendation to swap.

Products with Perilla Oil

Search all

49 products whose verified label declares Perilla Oil — not every bottle that mentions it in a title.