Mangosteen
10 benefits mapped to clinical evidence across supplements.
Dose per serving from products
49 products in our catalogue print how much Mangosteen a serving holds.
Most common: 100 mg to 250 mg, 61% of 49 products.
| Dose per serving | Products |
|---|---|
| 10 mg or less | 1 |
| 10 mg to 25 mg | 5 |
| 25 mg to 50 mg | 4 |
| 50 mg to 100 mg | 2 |
| 100 mg to 250 mg | 30 |
| 250 mg to 500 mg | 6 |
| over 500 mg | 1 |
Benefit Evidence
Systemic inflammation ↓ CRP
Local gingival inflammation ↓ IL-1β/PGE2/MMP-8
Research sources
Inflammation (5)
- Effect of a mangosteen dietary supplement on human immune function: a randomized, double-blind, placebo-controlled trial
PubMed ID: 19697997
CRP decreased and immune cell markers changed after 30 days, indicating anti‑inflammatory/immunomodulatory effects (some pro‑inflammatory cytokines also rose).
- Evaluation of Mangosteen juice blend on biomarkers of inflammation in obese subjects: a pilot, dose finding study
PubMed ID: 19843321
Dose‑dependent HS‑CRP reduction in obese subjects (significant at highest dose) suggests anti‑inflammatory action at adequate dose.
- Clinical and microbiological efficacy of 4% Garcinia mangostana L. pericarp gel as local drug delivery in the treatment of chronic periodontitis: A randomized, controlled clinical trial
PubMed ID: 28321995
Adding 4% mangosteen gel to SRP improved clinical periodontal indices and reduced key pathogens at 3 months.
- The Clinical Effect of a Propolis and Mangosteen Extract Complex in Subjects with Gingivitis: A Randomized, Double-Blind, and Placebo-Controlled Clinical Trial
PubMed ID: 39275315
Propolis–mangosteen complex produced large reductions in multiple GCF pro‑inflammatory biomarkers (IL‑1β, PGE2, MMP‑8) vs placebo.
- Clinical and Immunological Efficacy of Mangosteen and Propolis Extracted Complex in Patients with Gingivitis: A Multi-Centered Randomized Controlled Clinical Trial
PubMed ID: 34444764
Oral MAEC supplement reduced gingival inflammation and crevicular IL‑6, reflecting improved local inflammatory balance.
Oral health (4)
- Clinical and Immunological Efficacy of Mangosteen and Propolis Extracted Complex in Patients with Gingivitis: A Multi-Centered Randomized Controlled Clinical Trial
PubMed ID: 34444764
Oral mangosteen+propolis supplement for 8 weeks reduced gingival inflammation and improved some PROMs with good safety.
- Effects of herbal mouthwash containing the pericarp extract of Garcinia mangostana L on halitosis, plaque and papillary bleeding index
PubMed ID: 17274236
Randomized trial showed mangosteen‑pericarp mouthwash significantly reduced volatile sulfur compounds and improved halitosis measures.
- The Clinical Effect of a Propolis and Mangosteen Extract Complex in Subjects with Gingivitis: A Randomized, Double-Blind, and Placebo-Controlled Clinical Trial
PubMed ID: 39275315
Propolis–mangosteen complex drastically lowered GCF inflammatory biomarkers, supporting improved periodontal health.
- Clinical and microbiological efficacy of 4% Garcinia mangostana L. pericarp gel as local drug delivery in the treatment of chronic periodontitis: A randomized, controlled clinical trial
PubMed ID: 28321995
Randomized clinical trial (25 vs 25) found 4% mangosteen gel adjunct produced clinically and microbiologically significant periodontal improvements.
Metabolism (3)
- Efficacy and tolerability of Meratrim for weight management: a randomized, double-blind, placebo-controlled study in healthy overweight human subjects
PubMed ID: 27558585
Meratrim (contains Garcinia mangostana) produced significant weight, waist and triglyceride improvements over 16 weeks.
- Efficacy and tolerability of an herbal formulation for weight management
PubMed ID: 23767862
Pooled trials with multi‑herb blend including Garcinia mangostana produced meaningful weight and metabolic marker improvements.
- Efficacy and tolerability of a novel herbal formulation for weight management
PubMed ID: 23784895
8‑week randomized trial of blend including mangosteen increased adiponectin and reduced weight/BMI.
Weight management (3)
- Efficacy and tolerability of a novel herbal formulation for weight management
PubMed ID: 23784895
8‑week randomized trial of the herbal blend including mangosteen demonstrated significant weight and BMI reductions versus placebo.
- Efficacy and tolerability of an herbal formulation for weight management
PubMed ID: 23767862
Pooled double‑blind trials including Garcinia mangostana showed large net weight and waist reductions (~5.2 kg).
- Efficacy and tolerability of Meratrim for weight management: a randomized, double-blind, placebo-controlled study in healthy overweight human subjects
PubMed ID: 27558585
16‑week RCT (Meratrim) produced ~5.1 kg greater weight loss versus placebo with significant waist and lipid benefits.
Heart health (2)
- Efficacy and tolerability of Meratrim for weight management: a randomized, double-blind, placebo-controlled study in healthy overweight human subjects
PubMed ID: 27558585
Meratrim produced favorable triglyceride and HDL changes, indicating cardiometabolic benefit in overweight adults.
- Efficacy and tolerability of an herbal formulation for weight management
PubMed ID: 23767862
Pooled trials reported improvements in cholesterol and triglycerides alongside weight loss, supporting heart‑related benefits.
Skin appearance (2)
- Clinical efficacy of herbal extracts in treatment of mild to moderate acne vulgaris: an 8-week, double-blinded, randomized, controlled trial
PubMed ID: 31424962
8‑week trial of a multi‑herbal blend including mangosteen reduced inflammatory and non‑inflammatory acne lesions and local inflammatory markers.
- A comparative study on the effectiveness of herbal extracts vs 2.5% benzoyl peroxide in the treatment of mild to moderate acne vulgaris
PubMed ID: 31012999
12‑week herbal extract regimen (including mangosteen) reduced acne comparably to benzoyl peroxide with higher adherence and satisfaction.
Hair growth (1)
- Biomolecules of Fermented Tropical Fruits and Fermenting Microbes as Regulators of Human Hair Loss, Hair Quality, and Scalp Microbiota
PubMed ID: 37189446
Large randomized, double‑blind trial showed significant objective increases in hair density, follicle ATP and reduced scalp lipid peroxidation with fermented mangosteen formula.
Mood balance (1)
- The efficacy of adjunctive Garcinia mangostana Linn. (mangosteen) pericarp extract for bipolar depression: 24-week randomised controlled trial
PubMed ID: 40637133
24‑week adjunctive mangosteen pericarp in bipolar depression produced modest but statistically significant improvements in depression/anxiety and functioning at week 24.
Immune support (1)
- Effect of a mangosteen dietary supplement on human immune function: a randomized, double-blind, placebo-controlled trial
PubMed ID: 19697997
30‑day xanthone‑rich product lowered CRP and altered T‑helper cell frequency (immunomodulatory changes).
Exercise recovery (1)
- Combined extracts of Garcinia mangostana fruit rind and Cinnamomum tamala leaf supplementation enhances muscle strength and endurance in resistance trained males
PubMed ID: 30348185
GMCT (mangosteen + C. tamala) increased strength, endurance and lean mass over 42 days in resistance‑trained men; multi‑ingredient limits attribution.
Similar by evidence
Supplements the same benefits carry qualifying findings for — a fact about the evidence graph, not a recommendation to swap.
Products with Mangosteen
Search all280 products whose verified label declares Mangosteen — not every bottle that mentions it in a title.