Gamma Oryzanol
8 benefits mapped to clinical evidence across supplements.
Dose per serving from products
91 products in our catalogue print how much Gamma Oryzanol a serving holds.
Most common: 10 mg to 25 mg and 100 mg to 250 mg, 27% of 91 products each.
| Dose per serving | Products |
|---|---|
| 10 mg or less | 2 |
| 10 mg to 25 mg | 25 |
| 25 mg to 50 mg | 12 |
| 50 mg to 100 mg | 18 |
| 100 mg to 250 mg | 25 |
| 250 mg to 500 mg | 9 |
Benefit Evidence
Research sources
Cholesterol (6)
- A blend of sesame oil and rice bran oil lowers blood pressure and improves the lipid profile in mild-to-moderate hypertensive patients
PubMed ID: 27055965
Large open dietary intervention with sesame+rice-bran oil blend markedly lowered LDL-C in hypertensives; rice bran oil (γ-oryzanol source) implicated but confounded by blend.
- Rice Bran Oil Containing Gamma-Oryzanol Improves Lipid Profiles and Antioxidant Status in Hyperlipidemic Subjects: A Randomized Double-Blind Controlled Trial
PubMed ID: 30265563
Dose-related LDL-C lowering in a double-blind RCT with rice bran oil containing γ-oryzanol supports a cholesterol-lowering effect within the oil matrix.
- Efficacy of Food Supplement Based on Monacolins, γ-Oryzanol, and γ-Aminobutyric Acid in Mild Dyslipidemia: A Randomized, Double-Blind, Parallel-Armed, Placebo-Controlled Clinical Trial
PubMed ID: 39275298
Randomized placebo-controlled multi-ingredient RYR product (monacolin K + γ-oryzanol + GABA) produced large LDL reductions; strong lipid signal though multiple actives likely responsible.
- Supplementing the standard diet with brown rice bran powder might effectively improve the metabolic syndrome characteristics and antioxidant status: an open label randomized controlled trial
PubMed ID: 39775811
Brown rice bran powder RCT lowered LDL-C in metabolic syndrome patients, supporting cholesterol benefit though bran contains multiple active components.
- Similar cholesterol-lowering properties of rice bran oil, with varied gamma-oryzanol, in mildly hypercholesterolemic men
PubMed ID: 15309429
Controlled feeding study showed rice bran oil reduced total and LDL cholesterol in mildly hypercholesterolemic men, implicating RBO (contains γ-oryzanol) in cholesterol lowering.
- Effects of combined dietary supplementation on oxidative and inflammatory status in dyslipidemic subjects
PubMed ID: 16487912
Multi-nutrient supplement including γ-oryzanol improved total cholesterol vs control over 4 months—supportive but not specific to γ-oryzanol.
Heart health (2)
- Daily consumption of γ-oryzanol-fortified canola oil, compared with unfortified canola and sunflower oils, resulted in a better improvement of certain cardiometabolic biomarkers of adult subjects with type 2 diabetes: a randomized controlled clinical trial
PubMed ID: 37817285
γ-oryzanol–fortified canola oil RCT lowered systolic BP (and improved metabolic markers) in T2DM patients, supporting cardiovascular risk-factor improvements in humans within an oil matrix.
- A blend of sesame oil and rice bran oil lowers blood pressure and improves the lipid profile in mild-to-moderate hypertensive patients
PubMed ID: 27055965
Large open dietary study replacing oil with sesame+rice-bran blend reduced systolic/diastolic BP and LDL in hypertensives; rice bran (γ-oryzanol-rich) implicated but effects confounded by blend and other factors.
Inflammation (2)
- Effects of combined dietary supplementation on oxidative and inflammatory status in dyslipidemic subjects
PubMed ID: 16487912
Multi-nutrient trial reported decreased TNF-α with the combination that included γ-oryzanol, indicating anti-inflammatory changes though attribution is uncertain.
- Added γ-oryzanol boosted anti-inflammatory effects of canola oil in adult subjects with type 2 diabetes: a randomized controlled clinical trial
PubMed ID: 37971692
RCT with γ-oryzanol–fortified canola oil showed large, significant reductions in hs-CRP, IL-6 and IFN-γ vs control, providing strong human evidence for anti-inflammatory effects (within oil matrix).
Blood sugar (2)
- Daily consumption of γ-oryzanol-fortified canola oil, compared with unfortified canola and sunflower oils, resulted in a better improvement of certain cardiometabolic biomarkers of adult subjects with type 2 diabetes: a randomized controlled clinical trial
PubMed ID: 37817285
12-week RCT in T2DM showed γ-oryzanol–fortified canola oil reduced HbA1c by ~0.7% and improved TG and BP, providing fairly strong human evidence for glycemic improvement within dietary oil substitution.
- Supplementing the standard diet with brown rice bran powder might effectively improve the metabolic syndrome characteristics and antioxidant status: an open label randomized controlled trial
PubMed ID: 39775811
Brown rice bran powder RCT reduced blood sugar in metabolic syndrome participants, supporting glucose-related benefit though multiple constituents in bran confound attribution.
Antioxidant (2)
- Rice Bran Oil Containing Gamma-Oryzanol Improves Lipid Profiles and Antioxidant Status in Hyperlipidemic Subjects: A Randomized Double-Blind Controlled Trial
PubMed ID: 30265563
RBO RCT showed dose-related increases in antioxidant measures (ORAC, FRAP) with higher γ-oryzanol-containing rice bran oil; effect likely from RBO matrix but supports antioxidant role.
- Effects of combined dietary supplementation on oxidative and inflammatory status in dyslipidemic subjects
PubMed ID: 16487912
Multi-nutrient trial that reported decreased ROS (oxidative stress) after 4 months in group containing γ-oryzanol, supporting antioxidant effects though attribution is confounded.
Mood balance (1)
- Efficacy of rice bran extract for alleviating depressive symptoms in adults: a randomized, double-blind, placebo-controlled trial
PubMed ID: 40409466
8-week RCT of rice bran extract (multi-component, includes γ-oryzanol) showed large, significant reductions in depressive symptom scores vs placebo, supporting mood benefits of rice bran extracts though specific role of γ-oryzanol is uncertain.
Weight management (1)
- Supplementing the standard diet with brown rice bran powder might effectively improve the metabolic syndrome characteristics and antioxidant status: an open label randomized controlled trial
PubMed ID: 39775811
Brown rice bran powder (source of γ-oryzanol) RCT in metabolic syndrome reduced weight and waist circumference; multiple components in bran make γ-oryzanol contribution plausible but uncertain.
Strength (1)
- Effects of gamma oryzanol supplementation on anthropometric measurements & muscular strength in healthy males following chronic resistance training
PubMed ID: 25109720
Small double-blind RCT during 9-week resistance training found modest increases in 1-RM bench press and leg curl with γ-oryzanol supplementation, supporting a possible small effect on strength.
Similar by evidence
Supplements the same benefits carry qualifying findings for — a fact about the evidence graph, not a recommendation to swap.
Products with Gamma Oryzanol
Search all119 products whose verified label declares Gamma Oryzanol — not every bottle that mentions it in a title.