Artichoke Extract
13 benefits mapped to clinical evidence across supplements.
Dose per serving from products
557 products in our catalogue print how much Artichoke Extract a serving holds.
Most common: 25 mg to 50 mg, 40% of 557 products.
| Dose per serving | Products |
|---|---|
| 10 mg or less | 19 |
| 10 mg to 25 mg | 37 |
| 25 mg to 50 mg | 223 |
| 50 mg to 100 mg | 106 |
| 100 mg to 250 mg | 93 |
| 250 mg to 500 mg | 45 |
| 500 mg to 1 g | 23 |
| over 1 g | 11 |
Dose per serving from research
14 study groups in 13 studies say how much Artichoke Extract participants took a day.
These are the doses the studies gave. They are not a recommendation.
Most common: 1 g to 2.5 g, 43% of 14 study groups.
| Daily dose | Study groups |
|---|---|
| 100 mg to 250 mg | 2 |
| 250 mg to 500 mg | 2 |
| 500 mg to 1 g | 4 |
| 1 g to 2.5 g | 6 |
Benefit Evidence
Research sources
Cholesterol (9)
- Effect on LDL-cholesterol of a large dose of a dietary supplement with plant extracts in subjects with untreated moderate hypercholesterolaemia: a randomised, double-blind, placebo-controlled study
PubMed ID: 23266743
Multi‑ingredient supplement including artichoke lowered LDL over 4 weeks; attribution to artichoke alone limited.
- Efficacy of Artichoke dry extract in patients with hyperlipoproteinemia
PubMed ID: 10758778
Large double‑blind RCT showing substantial decreases in total cholesterol, LDL and LDL/HDL ratio with artichoke extract alone.
- A Randomized, Double-Blind, Placebo-Controlled Clinical Trial on the Effect of a Dietary Supplement Containing Dry Artichoke and Bergamot Extracts on Metabolic and Vascular Risk Factors in Individuals with Suboptimal Cholesterol Levels
PubMed ID: 38892519
Dry artichoke+bergamot extract lowered TC and LDL and improved hs‑CRP in a 12‑week RCT (combination product).
- LDL-cholesterol-lowering effect of a dietary supplement with plant extracts in subjects with moderate hypercholesterolemia
PubMed ID: 22527287
Multi‑ingredient supplement including artichoke led to marked LDL and TC reductions; specific artichoke contribution uncertain.
- Effect of Dietary Supplementation with Eufortyn(®) Colesterolo Plus on Serum Lipids, Endothelial Reactivity, Indexes of Non-Alcoholic Fatty Liver Disease and Systemic Inflammation in Healthy Subjects with Polygenic Hypercholesterolemia: The ANEMONE Study
PubMed ID: 35631240
Combined artichoke+bergamot nutraceutical lowered TC and LDL vs placebo, with improvements in non‑HDL and hs‑CRP.
- Artichoke and Bergamot Phytosome Alliance: A Randomized Double Blind Clinical Trial in Mild Hypercholesterolemia
PubMed ID: 35010984
Bergamot+artichoke phytosome randomized trial reduced total and LDL cholesterol and raised HDL (combination product).
- Three-arm, placebo-controlled, randomized clinical trial evaluating the metabolic effect of a combined nutraceutical containing a bergamot standardized flavonoid extract in dyslipidemic overweight subjects
PubMed ID: 31225673
Nutraceutical including artichoke improved LDL and triglycerides in overweight dyslipidemic adults (multi‑ingredient trial).
- Beneficial effects of artichoke leaf extract supplementation on increasing HDL-cholesterol in subjects with primary mild hypercholesterolaemia: a double-blind, randomized, placebo-controlled trial
PubMed ID: 22746542
RCT showed HDL increase and LDL/total cholesterol reductions with artichoke leaf extract.
- A combined natural supplement lowers LDL cholesterol in subjects with moderate untreated hypercholesterolemia: a randomized placebo-controlled trial
PubMed ID: 23815518
Randomized trial of combination product including artichoke produced ~14% LDL reduction vs placebo.
Heart health (6)
- A combined natural supplement lowers LDL cholesterol in subjects with moderate untreated hypercholesterolemia: a randomized placebo-controlled trial
PubMed ID: 23815518
Randomized trial of a supplement containing artichoke (plus other ingredients) produced significant LDL reductions vs placebo.
- LDL-cholesterol-lowering effect of a dietary supplement with plant extracts in subjects with moderate hypercholesterolemia
PubMed ID: 22527287
Multi‑ingredient supplement including artichoke produced marked LDL/TC lowering; attribution to artichoke alone uncertain.
- Effect of Dietary Supplementation with Eufortyn(®) Colesterolo Plus on Serum Lipids, Endothelial Reactivity, Indexes of Non-Alcoholic Fatty Liver Disease and Systemic Inflammation in Healthy Subjects with Polygenic Hypercholesterolemia: The ANEMONE Study
PubMed ID: 35631240
Nutraceutical with artichoke and bergamot improved TC/LDL, hs‑CRP and endothelial function (multi‑ingredient formulation).
- A Randomized, Double-Blind, Placebo-Controlled Clinical Trial on the Effect of a Dietary Supplement Containing Dry Artichoke and Bergamot Extracts on Metabolic and Vascular Risk Factors in Individuals with Suboptimal Cholesterol Levels
PubMed ID: 38892519
Dry artichoke+bergamot trial improved lipids (TC, LDL, TG) and reduced hs‑CRP, supporting cardiometabolic benefit for the combination.
- Efficacy of Artichoke dry extract in patients with hyperlipoproteinemia
PubMed ID: 10758778
Large double‑blind RCT (n=143) showing substantial reductions in total cholesterol, LDL and LDL/HDL with artichoke extract alone.
- Beneficial effects of artichoke leaf extract supplementation on increasing HDL-cholesterol in subjects with primary mild hypercholesterolaemia: a double-blind, randomized, placebo-controlled trial
PubMed ID: 22746542
Double‑blind RCT (n=92) reported increased HDL and reduced LDL/total cholesterol with artichoke leaf extract.
Fat burn (4)
- A Randomized, Double-Blind, Placebo-Controlled Clinical Trial on the Effect of a Dietary Supplement Containing Dry Artichoke and Bergamot Extracts on Metabolic and Vascular Risk Factors in Individuals with Suboptimal Cholesterol Levels
PubMed ID: 38892519
Dry artichoke+bergamot extract reduced triglycerides and improved lipid profile in a 12‑week RCT.
- Artichoke and Bergamot Phytosome Alliance: A Randomized Double Blind Clinical Trial in Mild Hypercholesterolemia
PubMed ID: 35010984
Bergamot+artichoke reduced visceral adipose tissue and improved lipid profile, suggesting benefit for fat metabolism (combo product).
- Three-arm, placebo-controlled, randomized clinical trial evaluating the metabolic effect of a combined nutraceutical containing a bergamot standardized flavonoid extract in dyslipidemic overweight subjects
PubMed ID: 31225673
Multi‑ingredient nutraceutical including artichoke lowered triglycerides and LDL and improved HOMA‑IR in dyslipidemic overweight adults.
- Effects of artichoke leaf extract supplementation on metabolic parameters in women with metabolic syndrome: Influence of TCF7L2-rs7903146 and FTO-rs9939609 polymorphisms
PubMed ID: 29193419
Small RCT found genotype‑specific triglyceride reduction in women with metabolic syndrome (FTO A‑allele carriers) after artichoke extract.
Digestive support (3)
- Artichoke leaf extract reduces mild dyspepsia in an open study
PubMed ID: 12587688
Large open postal study reported substantial dyspepsia symptom and quality‑of‑life improvement (non‑blinded).
- Efficacy of artichoke leaf extract in the treatment of patients with functional dyspepsia: a six-week placebo-controlled, double-blind, multicentre trial
PubMed ID: 14653829
Well‑conducted RCT demonstrating improved overall dyspepsia symptoms and quality of life vs placebo.
- A double-blind, placebo-controlled, cross-over study to establish the bifidogenic effect of a very-long-chain inulin extracted from globe artichoke (Cynara scolymus) in healthy human subjects
PubMed ID: 20591206
Artichoke‑derived inulin produced prebiotic changes (bifidobacteria/lactobacilli) commonly associated with improved bowel regularity.
Gut health (3)
- Enhancing gut microbiota and microbial function with inulin supplementation in children with obesity
PubMed ID: 39033197
Jerusalem artichoke inulin in children with obesity increased microbiome diversity and beneficial taxa (strong microbiome evidence).
- Effects of inulin supplementation on body composition and metabolic outcomes in children with obesity
PubMed ID: 35906473
Jerusalem artichoke inulin altered body composition and (in related reports) microbiome signals; supports prebiotic/microbiome effects.
- A double-blind, placebo-controlled, cross-over study to establish the bifidogenic effect of a very-long-chain inulin extracted from globe artichoke (Cynara scolymus) in healthy human subjects
PubMed ID: 20591206
Randomized double‑blind crossover trial showed artichoke‑derived inulin significantly increased faecal bifidobacteria and lactobacilli and reduced Bacteroides‑Prevotella.
Bloating & gas (2)
- Efficacy of artichoke leaf extract in the treatment of patients with functional dyspepsia: a six-week placebo-controlled, double-blind, multicentre trial
PubMed ID: 14653829
Double‑blind RCT in functional dyspepsia showing greater symptom relief (includes bloating) vs placebo.
- Artichoke leaf extract reduces mild dyspepsia in an open study
PubMed ID: 12587688
Large open study reported ~40% reduction in dyspepsia symptoms (subjective, non‑blinded so lower confidence).
Detoxification (2)
- A new nutraceutical (Livogen Plus®) improves liver steatosis in adults with non-alcoholic fatty liver disease
PubMed ID: 35986358
Multi‑ingredient RCT including artichoke reduced liver fat (CAP) and improved HOMA‑IR; artichoke contribution uncertain but supports liver benefit in the tested formulations.
- Efficacy of artichoke leaf extract in non-alcoholic fatty liver disease: A pilot double-blind randomized controlled trial
PubMed ID: 29520889
RCT in NAFLD showed improved liver ultrasound and lowered ALT/AST—strong direct evidence of liver (detox) support.
Liver support (2)
- A new nutraceutical (Livogen Plus®) improves liver steatosis in adults with non-alcoholic fatty liver disease
PubMed ID: 35986358
Large multi‑ingredient RCT including artichoke reduced CAP (liver fat) and improved steatosis grade and HOMA‑IR.
- Efficacy of artichoke leaf extract in non-alcoholic fatty liver disease: A pilot double-blind randomized controlled trial
PubMed ID: 29520889
RCT in NAFLD showed marked improvements in liver ultrasound measures and lowered ALT/AST with artichoke leaf extract.
Inflammation (2)
- A Randomized, Double-Blind, Placebo-Controlled Clinical Trial on the Effect of a Dietary Supplement Containing Dry Artichoke and Bergamot Extracts on Metabolic and Vascular Risk Factors in Individuals with Suboptimal Cholesterol Levels
PubMed ID: 38892519
Dry artichoke+bergamot extract reduced hs‑CRP along with lipid improvements in a randomized trial.
- Effect of Dietary Supplementation with Eufortyn(®) Colesterolo Plus on Serum Lipids, Endothelial Reactivity, Indexes of Non-Alcoholic Fatty Liver Disease and Systemic Inflammation in Healthy Subjects with Polygenic Hypercholesterolemia: The ANEMONE Study
PubMed ID: 35631240
Combined nutraceutical with artichoke decreased hs‑CRP and improved endothelial reactivity (RCT evidence for anti‑inflammatory/vascular benefit).
Blood sugar (2)
- TCF7L2-rs7903146 polymorphism modulates the effect of artichoke leaf extract supplementation on insulin resistance in metabolic syndrome: a randomized, double-blind, placebo-controlled trial
PubMed ID: 30177026
RCT found genotype‑dependent reductions in insulin and HOMA‑IR (TCF7L2 subgroup), supporting potential glycemic benefit in genetic subgroups.
- Metabolic management in overweight subjects with naive impaired fasting glycaemia by means of a highly standardized extract from Cynara scolymus: a double-blind, placebo-controlled, randomized clinical trial
PubMed ID: 23440660
Double‑blind RCT of artichoke extract alone in overweight subjects with impaired fasting glucose showed reductions in fasting glucose, HOMA and HbA1c.
Antioxidant (1)
- Antioxidant response to artichoke leaf extract supplementation in metabolic syndrome: A double-blind placebo-controlled randomized clinical trial
PubMed ID: 28410922
Randonized trial in metabolic syndrome lowered oxidized LDL (ox‑LDL), an oxidative stress marker, though other antioxidant markers did not change.
Weight management (1)
- Artichoke and Bergamot Phytosome Alliance: A Randomized Double Blind Clinical Trial in Mild Hypercholesterolemia
PubMed ID: 35010984
Bergamot+artichoke phytosome trial reduced body weight (~1.19 kg), visceral adipose tissue and improved lipids over 2 months.
Appetite suppression (1)
- Appetite control and glycaemia reduction in overweight subjects treated with a combination of two highly standardized extracts from Phaseolus vulgaris and Cynara scolymus
PubMed ID: 21308825
Study of artichoke plus Phaseolus reported increased feelings of fullness (significant Haber score change); product was combined so attribution uncertain but effect strong.
Similar by evidence
Supplements the same benefits carry qualifying findings for — a fact about the evidence graph, not a recommendation to swap.
Products with Artichoke Extract
Search all1080 products whose verified label declares Artichoke Extract — not every bottle that mentions it in a title.
Being studied right now
Recruiting clinical trials registered on ClinicalTrials.gov. A trial in progress has no result yet — this is what the field is asking, not what it found.