Astragalus
17 benefits mapped to clinical evidence across supplements.
Dose per serving from products
253 products in our catalogue print how much Astragalus a serving holds.
Most common: 25 mg to 50 mg, 23% of 253 products.
| Dose per serving | Products |
|---|---|
| 10 mg or less | 7 |
| 10 mg to 25 mg | 24 |
| 25 mg to 50 mg | 58 |
| 50 mg to 100 mg | 47 |
| 100 mg to 250 mg | 46 |
| 250 mg to 500 mg | 24 |
| 500 mg to 1 g | 22 |
| 1 g to 2.5 g | 24 |
| over 2.5 g | 1 |
Dose per serving from research
21 study groups in 16 studies say how much Astragalus participants took a day.
These are the doses the studies gave. They are not a recommendation.
Most common: 5 g to 10 g, 29% of 21 study groups.
| Daily dose | Study groups |
|---|---|
| 10 mg or less | 1 |
| 10 mg to 25 mg | 1 |
| 25 mg to 50 mg | 0 |
| 50 mg to 100 mg | 0 |
| 100 mg to 250 mg | 0 |
| 250 mg to 500 mg | 1 |
| 500 mg to 1 g | 3 |
| 1 g to 2.5 g | 0 |
| 2.5 g to 5 g | 4 |
| 5 g to 10 g | 6 |
| 10 g to 25 g | 3 |
| 25 g to 50 g | 2 |
Benefit Evidence
Immune/infection + lower
Recovery time -26%
Inflammation/renal protection +
Immune/infection + lower
Recovery time -26%
Inflammation/renal protection +
Research sources
Immune support (24)
- Immunopotentiating effects of four Chinese herbal polysaccharides administered at vaccination in chickens
PubMed ID: 18029798
Large poultry study: astragalus polysaccharide boosted vaccine antibody and T‑cell responses—preclinical immune support.
- [Modulatory effect of Astragalus membranaceus on Th1/Th2 cytokine in patients with herpes simplex keratitis]
PubMed ID: 15015443
Large RCT showing Th1/Th2 cytokine rebalancing in herpes keratitis—clear immunomodulatory effect.
- Efficacy and safety of zidovudine and zalcitabine combined with a combination of herbs in the treatment of HIV-infected Thai patients
PubMed ID: 16124442
Herbal combo added to ART increased CD4 and reduced HIV RNA; herb composition unclear but suggests immune benefit.
- Effect of astragalus injection on serious abdominal traumatic patients' cellular immunity
PubMed ID: 16571280
RCT: Astragalus aided restoration of CD4/CD8 after severe abdominal injury—direct immune recovery evidence.
- [Effects of radix Astragali injection on apoptosis of lymphocytes and immune function in patients with systemic lupus erythematosus]
PubMed ID: 16883914
SLE RCT: normalized T‑cell subsets and apoptosis markers—strong immunomodulatory signal.
- Clinical study on effect of Astragalus Injection and its immuno-regulation action in treating chronic aplastic anemia
PubMed ID: 17609906
Chronic aplastic anemia RCT: improved blood counts and reduced TNF/IL‑2 when Astragalus added—immune/hematologic benefit.
- [Effect of intravenous drip infusion of cyclophosphamide with high-dose Astragalus injection in treating lupus nephritis]
PubMed ID: 17498486
Lupus nephritis RCT: high‑dose Astragalus lowered infections and modulated immune markers when added to CTX.
- [Effect of cellular immune supportive treatment on immunity of esophageal carcinoma patients after modern two-field lymph node dissection]
PubMed ID: 17626759
Postoperative Shenqi (contains Astragalus) increased CD3+CD4+ and CD4/CD8 ratio in humans — direct immunomodulatory signal though multi‑herb formula limits specificity to Astragalus.
- [Effect of Astragalus on cytokines in patients undergoing heart valve replacement]
PubMed ID: 18655554
Perioperative Astragalus added to CPB prime reduced proinflammatory cytokines and raised IL‑10 in humans — clear immune/inflammatory modulation in a randomized setting.
- [Effect of compound astragalus recipe on lymphocyte subset, immunoglobulin and complements in patients with myasthenia gravia]
PubMed ID: 19526753
Compound Astragalus recipe altered lymphocyte subsets and complements in myasthenia gravis patients (RCT vs prednisone) — clinical immunomodulation evidence, multi‑component formula.
- Efficacy and safety of Astragalus membranaceus in the treatment of patients with seasonal allergic rhinitis
PubMed ID: 19504468
Astragalus‑containing supplement reduced rhinorrhea intensity and showed signals of symptom/QoL benefit in seasonal allergic rhinitis — suggests improved resistance to upper respiratory symptoms.
- [Clinical study of astragalus's preventing the recurrence of asthma in children]
PubMed ID: 21910341
In children with asthma, Astragalus reduced recurrence and modulated Th1/Th2 cytokines (greatest effect when combined with steroids) — clinical immune‑related benefit though confounded by combination therapy.
- [Effects of Radix Astragali on IL-1beta, TNF-alpha and antigen expression of peripheral blood mononuclear cells in patients with Graves disease]
PubMed ID: 22303710
RCT in Graves patients showed Astragalus addition lowered IL‑1β, TNF‑α and reduced immune cell activation markers.
- [Effects of Hengyan medicinal recipe on the regulation of immunity in patients with severe sepsis: a prospective clinical trial]
PubMed ID: 21315002
Also supports inflammation/immune findings (duplicate entry to reflect both IL and T‑cell effects).
- [Effects of Huangqi injection on infection factors in children with acute lymphoblastic leukemia]
PubMed ID: 24568907
Pediatric ALL RCT: Huangqi injections during chemo reduced infection rates and increased neutrophil counts (strong immune effect).
- Effects of antibacterial peptide on cellular immunity in weaned piglets
PubMed ID: 25403191
Weaned piglet study: Astragalus polysaccharide increased splenic T‑cell proliferation and peripheral T‑cell counts (robust cellular immune changes in animals).
- [Astragalus Granule Combined Auricular Point Sticking for Cough Variant Asthma in Children]
PubMed ID: 30641621
Astragalus granules reduced IgE, eosinophils and altered cytokines in children with cough-variant asthma — direct immunomodulatory effects in humans.
- A Randomized Controlled Trial Comparing a New D-Mannose-based Dietary Supplement to Placebo for the Treatment of Uncomplicated Escherichia coli Urinary Tract Infections
PubMed ID: 36621376
Multi-ingredient supplement including Astragalus produced large clinical/bacteriologic cures for UTI — suggests immune/antimicrobial benefit though multi-component.
- [Treatment of leucopenia with pure Astragalus preparation--an analysis of 115 leucopenic cases]
PubMed ID: 8580691
Pure Astragalus preparation produced dose‑dependent, clinically meaningful increases in WBC and leukopenia recovery.
- [Observation on effect of supplementary treatment by Astragalus injection in treating senile pulmonary tuberculosis patients]
PubMed ID: 12577419
Adjunctive Astragalus with TB therapy increased erythrocyte immune function (RBC‑C3b rosette) and improved sputum/X‑ray outcomes.
- [Effect of huangqi zengmian powder on interstitial response in patients with esophageal cancer at peri-operational period]
PubMed ID: 12577329
Perioperative Astragalus-containing powder increased local lymphocytic aggregation and mastocyte counts in tumor tissue (local immune activation).
- [Clinical study on effect of Astragalus in efficacy enhancing and toxicity reducing of chemotherapy in patients of malignant tumor]
PubMed ID: 12592686
RCT: Astragalus adjunct preserved WBC/platelets and improved CD4/CD8—direct immune-support signal.
- [Effect of astragalus injection combined with chemotherapy on quality of life in patients with advanced non-small cell lung cancer]
PubMed ID: 14626183
Advanced lung cancer RCT: adjunct Astragalus improved survival and QoL—likely via immune modulation.
- [Effect of milkvetch injection on immune function of children with tetralogy of Fallot after radical operation]
PubMed ID: 15307696
Post-op pediatric trial normalized immunoglobulins and lymphocyte subsets—robust immune modulation.
Detoxification (20)
- [Intervention of astragalus injection on the kidney injury after cardiopulmonary bypass of infants with congenital heart disease]
PubMed ID: 21812263
Infant CPB randomized study: Astragalus lowered postoperative TNF‑α/IL‑6 and urinary NAG — supports renal tubular protection in a vulnerable population.
- The protective effects of the traditional Chinese herbs against renal damage induced by extracorporeal shock wave lithotripsy: a clinical study
PubMed ID: 20607528
After ESWL, herbal treatment including Astragalus reduced urinary enzyme elevations and β2‑microglobulin vs control — protective effect on renal tubular injury markers.
- [Effects of astragalus injection on renal function in patients after cardiac valve replacement with cardiopulmonary bypass]
PubMed ID: 19526755
Randomized perioperative trial: Astragalus injection associated with smaller increases in BUN/Cr and urinary tubular injury markers after CPB — strong clinical renal‑protective evidence.
- [Effects of Astragalous Injection on oxidative stress status in maintenance hemodialysis patients]
PubMed ID: 18471409
Hemodialysis patients receiving Astragalus injection showed reduced oxidative stress and CRP — supportive of kidney‑related oxidative/inflammatory benefit.
- [Integrated treatment of traditional Chinese medicine and western medicine for early- and intermediate-stage diabetic nephropathy]
PubMed ID: 17666348
Multi‑herb preparation containing Astragalus improved proteinuria and fibrinogen in diabetic nephropathy patients — clinically meaningful renal endpoint improvements though multi‑component.
- [Effect of intravenous drip infusion of cyclophosphamide with high-dose Astragalus injection in treating lupus nephritis]
PubMed ID: 17498486
Lupus nephritis RCT: Astragalus + CTX decreased 24h urine protein and improved albumin—renal benefit.
- [Effect of Astragalus injection on platelet function and plasma endothelin in patients with early stage diabetic nephropathy]
PubMed ID: 12577356
Randomized study in early diabetic nephropathy: Astragalus injection reduced urinary albumin excretion and endothelin/platelet activation markers.
- A clinical investigation on 30 cases of senile benign renal arteriolosclerosis treated by huang qi gu jing yin
PubMed ID: 11789320
Astragalus‑containing decoction reported higher effectiveness rates in elderly renal arteriolosclerosis patients (clinical renal endpoint improvement).
- [Protective effects of astragali injection on tubular in patients with primary nephrotic syndrome]
PubMed ID: 16145898
RCT in primary nephrotic syndrome: decreased tubular injury markers and 24h protein, increased serum albumin—strong renal benefit.
- [Clinical observation on treatment of early diabetic nephropathy by milkvetch injection combined with captopril]
PubMed ID: 16355614
Three‑arm trial: Astragalus + captopril produced greatest UAER reduction and metabolic improvements—renal protection signal.
- [Effects of Mongolia Astragali Radix in protecting early cardiac and nephritic functions of patients of hypertension with metabolic syndrome]
PubMed ID: 28929695
Astragali Radix reduced microalbuminuria in hypertensive metabolic-syndrome patients — clinical renal benefit in larger randomized study.
- Add-on astragalus in type 2 diabetes and chronic kidney disease: A multi-center, assessor-blind, randomized controlled trial
PubMed ID: 38810556
48-week randomized trial: oral Astragalus slowed eGFR decline by 4.6 ml/min/1.73m2/year and lowered SBP in T2DM patients with macroalbuminuria — direct kidney-protective evidence.
- [Effects and Efficacy of Wenyang Huayin Yangxin Prescription on the Traditional Chinese Medicine Syndromes of Patients With Chronic Heart Failure Combined With Diuretic Resistance]
PubMed ID: 40109465
In diuretic‑resistant CHF patients, the TCM formula (including Astragalus) increased 24h urine volume and fractional excretion of sodium—direct renal/diuresis relevance.
- [Effect of Astragali and Angelica particle on proteinuria in Chinese patients with primary glomerulonephritis]
PubMed ID: 27468543
Multicenter RCT of an Astragali-containing formulation produced marked, sustained proteinuria reduction in primary glomerulonephritis — strong renal-support evidence (multi-herb).
- [Efficacy observation of Guan's quadruple therapy for kidney disease on the treatment of chronic renal failure]
PubMed ID: 25233647
Chronic renal failure trial using multi‑modal therapy including Astragalus reported improved Scr, BUN and 24h protein, but intervention was multi‑component and open‑label.
- [Treating lupus nephritis by a drug pair of radix astragali and rehmanniae radix combined with glucocorticoid: a preliminary clinical study]
PubMed ID: 25223180
Lupus nephritis RCT with Astragalus+Rehmannia reduced 24h urinary protein and lowered need for added prednisone—renal benefit.
- [Treatment of chronic primary glomerulopathy patients of Shen deficiency and dampness heat syndrome by yishen qingli granule combined low-dose Tripterygium wilfordii multiglycoside tablet: a clinical efficacy observation]
PubMed ID: 24517060
Large trial: Astragalus‑containing granule plus standard care improved proteinuria control and overall effectiveness in chronic primary glomerulopathy.
- [Effects of tangshen recipe on the homocysteine metabolism of patients with diabetic nephropathy]
PubMed ID: 21910334
Tangshen recipe (with Astragalus) improved oxidative and methylation markers in diabetic nephropathy, indicating multi‑faceted kidney support.
- [Effects of Astragalus injection on renal tubular function in patients with IgA nephropathy]
PubMed ID: 16841664
IgA nephropathy RCT: decreased urinary RBP/UNAG and urine protein with Astragalus injection—robust renal support evidence.
- [Clinical observation on treatment of diabetic nephropathy with compound fructus arctii mixture]
PubMed ID: 15307694
Herbal mixture including Astragalus reduced 24h urinary albumin and improved lipids/glucose in diabetic nephropathy (confounded).
Inflammation (18)
- [Effects of astragalus on cardiac function and serum tumor necrosis factor-alpha level in patients with chronic heart failure]
PubMed ID: 20929124
Astragalus granule adjunct in CHF lowered TNF‑α — clinically relevant anti‑inflammatory signal accompanying functional improvements.
- [Effect of Astragalus saponin on vascular endothelial cell and its function in burn patients]
PubMed ID: 12575608
Astragalus saponin reduced endothelial injury and inflammatory markers (ET, NO) in burn patients, indicating anti‑inflammatory effects.
- TA-65, A Telomerase Activator improves Cardiovascular Markers in Patients with Metabolic Syndrome
PubMed ID: 29546832
TA-65 lowered TNF-α in metabolic-syndrome patients in a randomized crossover trial — human anti-inflammatory signal.
- [Effect of milkvetch injection on immune function of children with tetralogy of Fallot after radical operation]
PubMed ID: 15307696
Post‑op pediatric study showed IL‑6 and TNF‑α decreased to normal—anti‑inflammatory signal.
- [Effect of Astragalus injection on plasma levels of apoptosis-related factors in aged patients with chronic heart failure]
PubMed ID: 16181532
Significant decreases in TNF‑α and IL‑6 in CHF patients after Astragalus—direct anti‑inflammatory evidence.
- [Effect of astraglus injection on serum apoptosis relevant factors in patients with chronic heart failure]
PubMed ID: 15957829
CHF RCT showed reduced TNF‑α with improved cardiac function—anti‑inflammatory effect.
- [Effects of radix Astragali injection on apoptosis of lymphocytes and immune function in patients with systemic lupus erythematosus]
PubMed ID: 16883914
SLE trial decreased Fas and inflammatory/apoptosis markers alongside improved T‑cell markers.
- Clinical study on effect of Astragalus Injection and its immuno-regulation action in treating chronic aplastic anemia
PubMed ID: 17609906
Aplastic anemia RCT showed decreased TNF‑α/IL‑2 with Astragalus—anti‑inflammatory/immune‑modulatory effect.
- [Effect of intravenous drip infusion of cyclophosphamide with high-dose Astragalus injection in treating lupus nephritis]
PubMed ID: 17498486
Lupus nephritis RCT: lower infection rates and improved inflammatory/immune markers with Astragalus adjunct.
- [Effect of Astragalus on cytokines in patients undergoing heart valve replacement]
PubMed ID: 18655554
Perioperative Astragalus in CPB reduced TNF‑α and IL‑8 and increased IL‑10 — strong randomized evidence of anti‑inflammatory action.
- [Effects of Astragalous Injection on oxidative stress status in maintenance hemodialysis patients]
PubMed ID: 18471409
Reduced CRP and oxidative markers with Astragalus injection in hemodialysis patients — supports systemic anti‑inflammatory effects.
- The protective effects of the traditional Chinese herbs against renal damage induced by extracorporeal shock wave lithotripsy: a clinical study
PubMed ID: 20607528
Herbal regimen including Astragalus led to smaller post‑ESWL rises in TNF‑α, NO and ET‑1 vs control — human evidence of anti‑inflammatory effect in an injury model.
- [Intervention of astragalus injection on the kidney injury after cardiopulmonary bypass of infants with congenital heart disease]
PubMed ID: 21812263
Infant CPB trial: perioperative Astragalus reduced postoperative TNF‑α and IL‑6 and urinary NAG — supports anti‑inflammatory and organ‑protective effects in vulnerable patients.
- [Effects of Radix Astragali on IL-1beta, TNF-alpha and antigen expression of peripheral blood mononuclear cells in patients with Graves disease]
PubMed ID: 22303710
Graves RCT: Astragalus addition led to greater decreases in IL‑1β and TNF‑α vs methimazole alone.
- [Effects of Hengyan medicinal recipe on the regulation of immunity in patients with severe sepsis: a prospective clinical trial]
PubMed ID: 21315002
Severe sepsis multi‑herb formula including Astragalus lowered IL‑6/IL‑10 and affected inflammatory profile.
- [Treatment of severe active systemic lupus erythematosus by PMC therapy combined langchuang fuzheng jiedu capsule: a clinical observation]
PubMed ID: 24432670
SLE study with Astragalus‑containing capsule reduced SLEDAI and ESR and allowed lower steroid dosing—anti‑inflammatory effect in autoimmune disease (multi‑herb).
- [Treatment of Chronic Endometritis by Penning Granule: a Clinical Randomized Controlled Trial]
PubMed ID: 30645842
Multi-herb granule (includes Astragalus) reduced endometrial inflammation markers (CD38, HIF-1α) and improved histology vs antibiotics — direct anti-inflammatory clinical effect.
- Effects of huoxin formula on the arterial functions of patients with coronary heart disease
PubMed ID: 31199705
Huoxin adjunct reduced CRP/IL‑18/TNF‑α/IL‑17 and MMP‑9 more than control — strong anti-inflammatory signal for the multi-herb formula including Astragalus.
Heart health (14)
- [Study on effect of Astragalus injection in treating congestive heart failure]
PubMed ID: 12575607
Randomized trial: Astragalus injection adjunct improved clinical heart‑function rates and LVEF/FS/SV/CO in congestive heart failure patients.
- [Effect of Milkvetch Injection on cardiac function and hemodynamics in children with tetralogy of Fallot after radical operation]
PubMed ID: 14714355
Post‑operative pediatric trial: faster hemodynamic recovery and shorter ICU stay—perioperative cardiac support signal.
- [Effect of Astragalus injection on plasma levels of apoptosis-related factors in aged patients with chronic heart failure]
PubMed ID: 16181532
Elderly CHF RCT: improved LVEF, decreased LV volumes and inflammatory/apoptosis markers—strong heart-support evidence.
- [Observation on collaborative treatment of dilated cardiomyopathy]
PubMed ID: 12577349
Integrated TCM+WM including Astragalus associated with better symptoms and fewer short‑term deaths in dilated cardiomyopathy (non‑specific regimen).
- [Effect of Astragalus membranaceus on erythrocyte sodium content and sodium transport in the coronary heart disease]
PubMed ID: 1667511
Direct IV Astragalus in coronary disease patients produced significant erythrocyte sodium‑pump changes; plausible cardiovascular benefit.
- [Effect of astragalus injection on immune function in patients with congestive heart failure]
PubMed ID: 12800417
CHF RCT showed improved NYHA scores and immune markers with Astragalus injection—direct cardiac benefit.
- Preventing effect of astragalus polysaccharide on cardiotoxicity induced by chemotherapy of epirubicin: A pilot study
PubMed ID: 35960075
Randomized trial: IV astragalus polysaccharide reduced troponin/CK‑MB and preserved LVEF vs chemo alone — direct cardioprotective evidence.
- [Effects and Efficacy of Wenyang Huayin Yangxin Prescription on the Traditional Chinese Medicine Syndromes of Patients With Chronic Heart Failure Combined With Diuretic Resistance]
PubMed ID: 40109465
Randomized inpatient study of a TCM formula (including Astragalus) in diuretic‑resistant CHF showed improved urine output, natriuresis and lower NT‑proBNP—strong heart‑support signal though multi‑herb.
- Effects of huoxin formula on the arterial functions of patients with coronary heart disease
PubMed ID: 31199705
Huoxin (multi-herb including Astragalus) improved arterial function and lowered inflammatory markers in stable coronary disease, but multi-herb and co-therapy confound attribution.
- Astragalus Membranaceus Improving Asymptomatic Left Ventricular Diastolic Dysfunction in Postmenopausal Hypertensive Women with Metabolic Syndrome: A Prospective, Open-Labeled, Randomized Controlled Trial
PubMed ID: 29483384
Large clinical trial showed dose-dependent improvements in diastolic function indices with Astragalus membranaceus — direct cardiac-support evidence.
- Clinical effect of Astragalus granule of different dosages on quality of life in patients with chronic heart failure
PubMed ID: 21390582
Randomized dose‑comparison: Astragalus granule improved LVEF, 6MWD and QoL in chronic heart failure in a dose‑dependent manner over 30 days — direct clinical cardiac benefit.
- [Effects of astragalus on cardiac function and serum tumor necrosis factor-alpha level in patients with chronic heart failure]
PubMed ID: 20929124
Adjunctive Astragalus granule in chronic heart failure reduced TNF‑α, increased LVEF and extended 6MWD after two weeks — randomized clinical heart‑function improvements.
- [Effect of astraglus injection on serum apoptosis relevant factors in patients with chronic heart failure]
PubMed ID: 15957829
CHF RCT: increased LVEF, decreased LVEDV and TNF‑α with Astragalus—consistent cardiac functional benefits.
- [Clinical study on effect of Astragalus injection on left ventricular remodeling and left ventricular function in patients with acute myocardial infarction]
PubMed ID: 12584831
Randomized AMI trial: Astragalus injection adjunct reduced adverse LV remodeling, improved LVEF and functional indices—strong cardioprotective signal.
Illness recovery (14)
- Effect of astragalus injection on serious abdominal traumatic patients' cellular immunity
PubMed ID: 16571280
Restoration of T‑cell markers after severe abdominal injury implies improved recovery trajectory.
- Effects of Astragalus membranaceus and Panax notoginseng Saponins Extract on the Pharmacokinetics of Whey Protein Absorption, Intestinal Permeability, and Muscle Function: A Pilot Study
PubMed ID: 41683325
Increased BCAA absorption and modest strength improvements support nutritional recovery/rehabilitation potential.
- Chronic fatigue syndrome post-COVID-19: triple-blind randomised clinical trial of Astragalus root extract
PubMed ID: 38834234
Astragalus root extract RCT lowered chronic fatigue prevalence post‑COVID—direct evidence for recovery support.
- Effect of Chinese Herbal Compound LC09 on Patients With Capecitabine-Associated Hand-Foot Syndrome: A Randomized, Double-Blind, and Parallel-Controlled Trial
PubMed ID: 32597691
Reduced HFS severity and pain facilitated better chemotherapy continuation and symptomatic recovery in treated patients.
- Effectiveness of Radix astragali and Salvia miltiorrhiza injection in treatment of skeletal muscle injury of aerobics athletes
PubMed ID: 30203777
Radix astragali + Salvia injection improved antioxidant and muscle-injury biomarkers and overall recovery metrics in aerobics athletes (large sample but combined therapy).
- [Effects of Huangqi injection on infection factors in children with acute lymphoblastic leukemia]
PubMed ID: 24568907
Huangqi injection during ALL induction chemo reduced infections and duration—direct recovery support during immunosuppressive therapy.
- [Intervention of astragalus injection on the kidney injury after cardiopulmonary bypass of infants with congenital heart disease]
PubMed ID: 21812263
Infant CPB study: perioperative Astragalus reduced cytokine rise and urinary NAG — evidence for organ‑protective recovery support in pediatric surgery.
- The protective effects of the traditional Chinese herbs against renal damage induced by extracorporeal shock wave lithotripsy: a clinical study
PubMed ID: 20607528
Multi‑herb regimen including Astragalus attenuated biochemical kidney injury and oxidative/inflammatory markers after ESWL — supports recovery from procedure‑related injury.
- [Effects of astragalus injection on renal function in patients after cardiac valve replacement with cardiopulmonary bypass]
PubMed ID: 19526755
Perioperative Astragalus injection reduced serum/urinary renal‑injury markers after cardiac surgery (CPB) — supports organ‑protective recovery post‑surgery.
- [Effect of Astragalus on cytokines in patients undergoing heart valve replacement]
PubMed ID: 18655554
Astragalus added to CPB prime reduced inflammatory cytokines and raised IL‑10 postoperatively — indicates improved inflammatory profile during recovery.
- [Effect of intravenous drip infusion of cyclophosphamide with high-dose Astragalus injection in treating lupus nephritis]
PubMed ID: 17498486
Lupus nephritis adjunctive therapy reduced infections and proteinuria and improved hematologic markers—supports recovery.
- [Effect of milkvetch injection on immune function of children with tetralogy of Fallot after radical operation]
PubMed ID: 15307696
Post‑operative immune normalization in children implies aided recovery.
- [Effect of Milkvetch Injection on cardiac function and hemodynamics in children with tetralogy of Fallot after radical operation]
PubMed ID: 14714355
Pediatric post‑op trial showed faster hemodynamic improvement and shorter ICU/recovery times with Astragalus injections.
- [Clinical study on effect of Astragalus in efficacy enhancing and toxicity reducing of chemotherapy in patients of malignant tumor]
PubMed ID: 12592686
Reduced cytopenias and better QoL during chemotherapy suggests facilitation of recovery from treatment stress.
Cell health (13)
- [Effect of Astragalus on cytokines in patients undergoing heart valve replacement]
PubMed ID: 18655554
CPB prime with Astragalus lowered proinflammatory cytokines and increased IL‑10 — anti‑inflammatory shifts that can reduce cellular injury.
- A Natural Astragalus-Based Nutritional Supplement Lengthens Telomeres in a Middle-Aged Population: A Randomized, Double-Blind, Placebo-Controlled Study
PubMed ID: 39275278
Randomized trial showed increased leukocyte telomere length and fewer very-short telomeres — direct cellular/protective biomarker improvements.
- Preventing effect of astragalus polysaccharide on cardiotoxicity induced by chemotherapy of epirubicin: A pilot study
PubMed ID: 35960075
IV astragalus polysaccharide reduced chemo-induced cardiac biomarker injury and preserved LVEF — indicates cellular protection against anthracycline toxicity.
- A Natural Product Telomerase Activator Lengthens Telomeres in Humans: A Randomized, Double Blind, and Placebo Controlled Study
PubMed ID: 26950204
TA-65 (Astragalus-derived telomerase activator) lengthened telomeres in older adults — direct cellular-level protective effect.
- Effects of Astragalus membranaceus root processed to different particle sizes on growth performance, antioxidant status, and serum metabolites of broiler chickens
PubMed ID: 23243245
Broiler study: Astragalus increased antioxidant enzymes (SOD, GSH‑Px) and reduced MDA—evidence of cellular oxidative protection in animals.
- [Effects of tangshen recipe on the homocysteine metabolism of patients with diabetic nephropathy]
PubMed ID: 21910334
Tangshen recipe (contains Astragalus) improved homocysteine‑related metabolism and oxidative‑stress markers in diabetic nephropathy — biochemical protection at cellular/metabolic level.
- The protective effects of the traditional Chinese herbs against renal damage induced by extracorporeal shock wave lithotripsy: a clinical study
PubMed ID: 20607528
Post‑ESWL randomized trial: multi‑herb regimen containing Astragalus attenuated rises in NO/ET‑1 and TNF‑α and preserved SOD activity — supports cellular/oxidative protection around injury.
- [Effects of astragalus injection on renal function in patients after cardiac valve replacement with cardiopulmonary bypass]
PubMed ID: 19526755
Perioperative Astragalus injection reduced serum/urinary markers of renal tubular injury after CPB — evidence of organ/cellular protection in humans.
- [Effects of Astragalous Injection on oxidative stress status in maintenance hemodialysis patients]
PubMed ID: 18471409
Hemodialysis RCT: Astragalus injection reduced AGEs, AOPP and MDA and CRP — robust human biochemical evidence of reduced oxidative/cellular stress.
- [Effect of intravenous drip infusion of cyclophosphamide with high-dose Astragalus injection in treating lupus nephritis]
PubMed ID: 17498486
Lupus nephritis trial reduced infections and renal proteinuria and improved hematologic parameters—supports organ/cellular protection.
- [Effects of radix Astragali injection on apoptosis of lymphocytes and immune function in patients with systemic lupus erythematosus]
PubMed ID: 16883914
SLE trial increased Bcl‑2 and decreased Fas expression—direct markers of reduced lymphocyte apoptosis/cellular protection.
- [Effect of Astragalus injection on plasma levels of apoptosis-related factors in aged patients with chronic heart failure]
PubMed ID: 16181532
Reduced apoptosis markers (sFas/sFasL) and inflammation in CHF—supports cellular protection.
- [Protective effects of astragali injection on tubular in patients with primary nephrotic syndrome]
PubMed ID: 16145898
Nephrotic syndrome RCT lowered tubular injury markers (RBP/NAG) and proteinuria—renal cellular protection signal.
Wellbeing (12)
- Effects of the traditional Chinese herb Astragalus membranaceus in patients with poststroke fatigue: A double-blind, randomized, controlled preliminary study
PubMed ID: 27773802
Astragalus improved fatigue, cognition and multiple QoL domains after stroke in an RCT — direct overall-wellness benefit.
- [Effects of Huangqi injection on infection factors in children with acute lymphoblastic leukemia]
PubMed ID: 24568907
Huangqi injections during ALL chemo lowered infections and improved neutrophil counts—clear clinical wellness benefit in pediatric oncology.
- Clinical effect of Astragalus granule of different dosages on quality of life in patients with chronic heart failure
PubMed ID: 21390582
Dose‑dependent improvements in QoL, LVEF and 6MWD in chronic heart failure suggest broad wellness benefits with Astragalus granule.
- Astragalus polysaccharide injection integrated with vinorelbine and cisplatin for patients with advanced non-small cell lung cancer: effects on quality of life and survival
PubMed ID: 21928106
Large RCT: Astragalus polysaccharide adjunct improved overall QOL and multiple symptom domains in advanced NSCLC patients — strong clinical evidence for wellness support.
- Myelophil, an extract mix of Astragali Radix and Salviae Radix, ameliorates chronic fatigue: a randomised, double-blind, controlled pilot study
PubMed ID: 19398067
Self‑reported fatigue improvement in chronic fatigue patients with Astragalus+Salvia indicates perceived wellness gains.
- [Effect of intravenous drip infusion of cyclophosphamide with high-dose Astragalus injection in treating lupus nephritis]
PubMed ID: 17498486
Lupus nephritis RCT improved multiple clinical outcomes including infections, albumin, RBC—meaningful overall benefit.
- [Effect of astragalus injection combined with chemotherapy on quality of life in patients with advanced non-small cell lung cancer]
PubMed ID: 14626183
Improved survival and QoL in NSCLC patients when Astragalus added to chemo—broad wellness signal.
- Effects of Astragalus membranaceus and Panax notoginseng Saponins Extract on the Pharmacokinetics of Whey Protein Absorption, Intestinal Permeability, and Muscle Function: A Pilot Study
PubMed ID: 41683325
Increased amino‑acid absorption and modest strength gains support functional wellness and recovery potential.
- Chronic fatigue syndrome post-COVID-19: triple-blind randomised clinical trial of Astragalus root extract
PubMed ID: 38834234
Astragalus root extract RCT reduced chronic fatigue in nurses — a clinically meaningful improvement in overall wellness.
- A Natural Astragalus-Based Nutritional Supplement Lengthens Telomeres in a Middle-Aged Population: A Randomized, Double-Blind, Placebo-Controlled Study
PubMed ID: 39275278
Telomere lengthening and reduced short-telomere fraction suggest systemic cellular benefits that could contribute to overall wellness.
- A Randomized Controlled Trial Comparing a New D-Mannose-based Dietary Supplement to Placebo for the Treatment of Uncomplicated Escherichia coli Urinary Tract Infections
PubMed ID: 36621376
Multi-ingredient supplement including Astragalus produced large clinical and microbiologic cures for UTIs — clear clinical wellness benefit for that regimen.
- Preventing effect of astragalus polysaccharide on cardiotoxicity induced by chemotherapy of epirubicin: A pilot study
PubMed ID: 35960075
Cardioprotective effects during cancer therapy likely contribute to improved clinical wellbeing and reduced treatment complications.
Energy & Fatigue (7)
- [Prospective clinical study of radix astragali and its compound prescription for treatment of β-thalassemia in children]
PubMed ID: 22613104
Astragalus increased hemoglobin by ~1 g/dL in β‑thalassemia children—likely to improve energy/oxygen delivery.
- Astragalus polysaccharide injection integrated with vinorelbine and cisplatin for patients with advanced non-small cell lung cancer: effects on quality of life and survival
PubMed ID: 21928106
Astragalus polysaccharide adjunct to chemotherapy improved fatigue and multiple QOL domains in NSCLC patients — clinical evidence of raised energy/wellness.
- Three-Component Herbal Tea Alleviates Prolonged Fatigue and Improves Sleep Quality: A Randomized Controlled Pilot Study
PubMed ID: 30482676
Herbal tea including Astragalus reduced prolonged fatigue vs no-intervention control — clinical signal for increased energy.
- Chronic fatigue syndrome post-COVID-19: triple-blind randomised clinical trial of Astragalus root extract
PubMed ID: 38834234
Triple‑blind RCT of Astragalus root extract significantly reduced chronic fatigue in nurses — direct evidence for increased energy/fatigue reduction.
- Effects of Astragalus membranaceus and Panax notoginseng Saponins Extract on the Pharmacokinetics of Whey Protein Absorption, Intestinal Permeability, and Muscle Function: A Pilot Study
PubMed ID: 41683325
Increased absorption of BCAAs and modest grip‑strength gains after Astragalus + Panax saponins support a role in physical energy/recovery.
- Myelophil, an extract mix of Astragali Radix and Salviae Radix, ameliorates chronic fatigue: a randomised, double-blind, controlled pilot study
PubMed ID: 19398067
Randomized pilot: Astragalus+Salvia reduced fatigue severity in adults with chronic fatigue — a direct signal for increased perceived energy.
- Effects of the traditional Chinese herb Astragalus membranaceus in patients with poststroke fatigue: A double-blind, randomized, controlled preliminary study
PubMed ID: 27773802
Randomized trial showed marked improvement in fatigue (BFI) in post-stroke patients taking Astragalus — strong human evidence for increased energy/fatigue reduction.
Blood circulation (6)
- [Effects of astragalus on cardiac function and serum tumor necrosis factor-alpha level in patients with chronic heart failure]
PubMed ID: 20929124
Astragalus adjunct increased LVEF and 6MWD and reduced TNF‑α in CHF patients — clinical evidence of improved cardiovascular function.
- [Clinical study on effect of Astragalus injection on left ventricular remodeling and left ventricular function in patients with acute myocardial infarction]
PubMed ID: 12584831
AMI study showed smaller adverse increases in LV volumes, better ejection/filling rates and improved endothelial markers—implying improved cardiac/vascular function.
- Effects of huoxin formula on the arterial functions of patients with coronary heart disease
PubMed ID: 31199705
Huoxin adjunct (contains Astragalus) improved IMT, ABI, and arterial stiffness measures vs control in stable coronary disease — direct circulation-related endpoints reported.
- [Effects and Efficacy of Wenyang Huayin Yangxin Prescription on the Traditional Chinese Medicine Syndromes of Patients With Chronic Heart Failure Combined With Diuretic Resistance]
PubMed ID: 40109465
Improvements in NT‑proBNP and diuresis in CHF suggest better hemodynamics and circulatory status (multi‑herb formula).
- [Prospective clinical study of radix astragali and its compound prescription for treatment of β-thalassemia in children]
PubMed ID: 22613104
Hemoglobin and RBC increases in β‑thalassemia improve oxygen‑carrying capacity and could enhance tissue perfusion/circulation.
- Clinical effect of Astragalus granule of different dosages on quality of life in patients with chronic heart failure
PubMed ID: 21390582
Dose‑dependent increases in LVEF and 6MWD in chronic heart failure indicate improved cardiac output and functional circulation.
Antioxidant (5)
- [Effects of Astragalous Injection on oxidative stress status in maintenance hemodialysis patients]
PubMed ID: 18471409
Strong human trial evidence: Astragalus injection lowered AGEs, AOPP and MDA in hemodialysis patients — robust antioxidant biomarker changes.
- [Clinical study on effect of Astragalus injection on left ventricular remodeling and left ventricular function in patients with acute myocardial infarction]
PubMed ID: 12584831
AMI trial showed decreased MDA and increased SOD with Astragalus injection adjunct—clinical antioxidant marker improvement.
- The protective effects of the traditional Chinese herbs against renal damage induced by extracorporeal shock wave lithotripsy: a clinical study
PubMed ID: 20607528
Post‑ESWL trial showed preservation of SOD activity and smaller rises in oxidative/inflammatory markers with Astragalus‑containing treatment — good antioxidant support.
- Effects of Astragalus membranaceus root processed to different particle sizes on growth performance, antioxidant status, and serum metabolites of broiler chickens
PubMed ID: 23243245
Broiler feeding RCT: increased TSOD and GSHPx and decreased MDA with Astragalus powder—strong animal evidence for antioxidant effects.
- [Effects of tangshen recipe on the homocysteine metabolism of patients with diabetic nephropathy]
PubMed ID: 21910334
Tangshen recipe (with Astragalus) improved glutathione/oxidative stress markers in diabetic nephropathy — clinical biochemical antioxidant signal.
Respiratory comfort (4)
- Efficacy and safety of Astragalus membranaceus in the treatment of patients with seasonal allergic rhinitis
PubMed ID: 19504468
Double‑blind RCT: Astragalus‑containing formula reduced rhinorrhea intensity in seasonal allergic rhinitis, with subgroup benefit — symptomatic respiratory relief.
- [Clinical study of astragalus's preventing the recurrence of asthma in children]
PubMed ID: 21910341
Randomized study in children found Astragalus reduced asthma recurrence and modulated cytokines (best effect when combined with steroids) — clinically relevant respiratory benefit.
- [Astragalus Granule Combined Auricular Point Sticking for Cough Variant Asthma in Children]
PubMed ID: 30641621
Astragalus granules (with standard inhaled meds) reduced inflammatory markers and sped cough resolution in children with cough-variant asthma — direct respiratory benefit.
- Jinbei oral liquid for idiopathic pulmonary fibrosis: a randomized placebo-controlled trial
PubMed ID: 39849152
26‑week RCT of a 12‑herb oral liquid (including Astragalus) in IPF showed a statistically significant TLC improvement—direct respiratory relevance though multi‑herb.
Healthy aging (4)
- A Natural Product Telomerase Activator Lengthens Telomeres in Humans: A Randomized, Double Blind, and Placebo Controlled Study
PubMed ID: 26950204
Low-dose TA-65 produced significant telomere lengthening over 12 months in older CMV+ adults — strong, direct aging-relevant biomarker evidence.
- [Effects of Astragalous Injection on oxidative stress status in maintenance hemodialysis patients]
PubMed ID: 18471409
Lowering AGEs and oxidative markers in hemodialysis patients is a mechanism relevant to biological aging — direct change in aging‑related biomarkers.
- A Natural Astragalus-Based Nutritional Supplement Lengthens Telomeres in a Middle-Aged Population: A Randomized, Double-Blind, Placebo-Controlled Study
PubMed ID: 39275278
Well-controlled randomized trial: significant leukocyte telomere lengthening and reduction in very-short telomeres — strong biomarker evidence for an anti‑aging cellular effect.
- Add-on astragalus in type 2 diabetes and chronic kidney disease: A multi-center, assessor-blind, randomized controlled trial
PubMed ID: 38810556
48-week trial in diabetic CKD slowed eGFR decline and lowered SBP — clinically meaningful organ-protective effect relevant to healthy aging.
Endurance (3)
- Clinical effect of Astragalus granule of different dosages on quality of life in patients with chronic heart failure
PubMed ID: 21390582
Dose‑dependent increases in 6‑minute walk distance in heart failure patients after Astragalus granule indicate clear improvement in functional stamina.
- Chronic fatigue syndrome post-COVID-19: triple-blind randomised clinical trial of Astragalus root extract
PubMed ID: 38834234
Reduction in chronic fatigue would be expected to increase perceived stamina/functional endurance.
- [Effects of astragalus on cardiac function and serum tumor necrosis factor-alpha level in patients with chronic heart failure]
PubMed ID: 20929124
Astragalus granule plus standard therapy increased 6MWD in chronic heart failure vs control (2‑week study) — direct functional stamina benefit.
Blood sugar (3)
- [Clinical observation on treatment of diabetic nephropathy with compound fructus arctii mixture]
PubMed ID: 15307694
Multi‑herb formula with Astragalus decreased postprandial glucose in diabetic nephropathy—confounded but relevant.
- [Clinical observation on treatment of early diabetic nephropathy by milkvetch injection combined with captopril]
PubMed ID: 16355614
Astragalus (alone or + captopril) groups showed decreased blood glucose and HbA1c in early diabetic nephropathy.
- Improving insulin resistance with traditional Chinese medicine in type 2 diabetic patients
PubMed ID: 19728183
Randomized trial in newly diagnosed T2DM: Tangible improvement in glucose disposal rate (insulin sensitivity) though multi‑herb TCM limits sole attribution to Astragalus.
Skin health (1)
- Effect of Chinese Herbal Compound LC09 on Patients With Capecitabine-Associated Hand-Foot Syndrome: A Randomized, Double-Blind, and Parallel-Controlled Trial
PubMed ID: 32597691
Topical LC09 (contains Astragalus) significantly reduced capecitabine-associated hand‑foot syndrome severity and pain in a randomized trial — direct skin-health benefit.
Mental clarity (1)
- Effects of the traditional Chinese herb Astragalus membranaceus in patients with poststroke fatigue: A double-blind, randomized, controlled preliminary study
PubMed ID: 27773802
Oral Astragalus improved cognitive domain scores in post-stroke fatigue RCT — moderate direct evidence for cognition benefit.
Digestive support (1)
- Effects of Astragalus membranaceus and Panax notoginseng Saponins Extract on the Pharmacokinetics of Whey Protein Absorption, Intestinal Permeability, and Muscle Function: A Pilot Study
PubMed ID: 41683325
Pilot RCT reported improved gut‑barrier markers and amino‑acid absorption—direct digestive relevance.
Similar by evidence
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Products with Astragalus
Search all751 products whose verified label declares Astragalus — not every bottle that mentions it in a title.
Being studied right now
Recruiting clinical trials registered on ClinicalTrials.gov. A trial in progress has no result yet — this is what the field is asking, not what it found.