Garlic
17 benefits mapped to clinical evidence across supplements.
Dose per serving from products
849 products in our catalogue print how much Garlic a serving holds.
Most common: 100 mg to 250 mg, 25% of 849 products.
| Dose per serving | Products |
|---|---|
| 5 mg or less | 33 |
| 5 mg to 10 mg | 13 |
| 10 mg to 25 mg | 42 |
| 25 mg to 50 mg | 135 |
| 50 mg to 100 mg | 195 |
| 100 mg to 250 mg | 209 |
| 250 mg to 500 mg | 145 |
| 500 mg to 1 g | 58 |
| over 1 g | 19 |
Dose per serving from research
88 study groups in 73 studies say how much Garlic participants took a day.
These are the doses the studies gave. They are not a recommendation.
Most common: 500 mg to 1 g, 44% of 88 study groups.
| Daily dose | Study groups |
|---|---|
| 100 mg or less | 5 |
| 100 mg to 250 mg | 5 |
| 250 mg to 500 mg | 13 |
| 500 mg to 1 g | 39 |
| 1 g to 2.5 g | 20 |
| 2.5 g to 5 g | 4 |
| over 5 g | 2 |
Commonly used together
18 of 93 study groups took Garlic with something else. Shown: what 3 or more different studies gave.
What was given together, not what works together.
| Taken with | Study groups |
|---|---|
| Fish Oil | 3 |
Benefit Evidence
Antibacterial -5.23×10^5
Anti-inflammatory improved
Antifungal cure +100%
Research sources
Heart health (47)
- Aged garlic extract improves adiponectin levels in subjects with metabolic syndrome: a double-blind, placebo-controlled, randomized, crossover study
PubMed ID: 23533302
AGE raised adiponectin in metabolic syndrome patients, a cardiometabolic protective change.
- Effects of an Optimized Aged Garlic Extract on Cardiovascular Disease Risk Factors in Moderate Hypercholesterolemic Subjects: A Randomized, Crossover, Double-Blind, Sustainedand Controlled Study
PubMed ID: 35276764
Optimized aged black garlic reduced diastolic BP in moderate hypercholesterolemia — beneficial cardiovascular effect.
- Antihypertensive Effects of an Optimized Aged Garlic Extract in Subjects with Grade I Hypertension and Antihypertensive Drug Therapy: A Randomized, Triple-Blind Controlled Trial
PubMed ID: 37686723
Low-dose aged black garlic modestly lowered home BP in medicated Grade I hypertensives — small supportive cardiac signal.
- Comparison of the efficacy and tolerance of a garlic preparation vs. bezafibrate
PubMed ID: 1288512
Randomized trial in hyperlipoproteinemia found garlic reduced lipids comparably to bezafibrate, supporting cardiovascular risk factor improvement.
- Relation of oxidative biomarkers, vascular dysfunction, and progression of coronary artery calcium
PubMed ID: 20152239
Sub-analysis linking improved oxidative/vascular biomarkers from AGE trials to less coronary calcification — mechanistic support for heart benefit.
- Aged Garlic Extract Reduces Low Attenuation Plaque in Coronary Arteries of Patients with Metabolic Syndrome in a Prospective Randomized Double-Blind Study
PubMed ID: 26764322
AGE reduced vulnerable (low-attenuation) coronary plaque in metabolic-syndrome patients in an RCT — strong plaque-stability signal.
- The effect of aged garlic extract on the atherosclerotic process - a randomized double-blind placebo-controlled trial
PubMed ID: 32349742
One-year AGE RCT lowered CAC progression and systolic BP and improved an inflammatory marker — clinically relevant heart outcomes.
- Beneficial effects of aged garlic extract and coenzyme Q10 on vascular elasticity and endothelial function: the FAITH randomized clinical trial
PubMed ID: 22858191
Aged garlic + CoQ10 RCT improved vascular elasticity and endothelial function, important cardioprotective markers.
- Efficacy of garlic (Allium sativum) on metabolic syndrome components in women with polycystic ovary syndrome: randomized controlled trial
PubMed ID: 40770379
In metabolic-syndrome/PCOS patients garlic reduced weight, LDL and SBP—favorable heart-risk factors.
- Effect of Encapsulated Purple Garlic Oil on Microvascular Function and the Components of Metabolic Syndrome: A Randomized Placebo-Controlled Study-The ENDOTALLIUM Study
PubMed ID: 38892688
Purple garlic oil decreased CRP and metabolic-syndrome components and improved microvascular function.
- Effect of garlic powder tablet on carotid intima-media thickness in patients with coronary artery disease: a preliminary randomized controlled trial
PubMed ID: 25573347
RCT in CAD patients showed prevention of CIMT progression—direct anti‑atherosclerotic benefit.
- Effect of garlic and fish-oil supplementation on serum lipid and lipoprotein concentrations in hypercholesterolemic men
PubMed ID: 9022529
Randomized trial in hypercholesterolemic men produced meaningful LDL/total‑cholesterol reductions.
- Hypertension and hyperlipidaemia: garlic helps in mild cases
PubMed ID: 2083170
Double‑blind RCT in mild hypertensives reduced diastolic BP and improved lipids—cardiovascular benefit.
- Treatment of hyperlipidaemia with garlic-powder tablets. Evidence from the German Association of General Practitioners' multicentric placebo-controlled double-blind study
PubMed ID: 2291748
Large multicenter RCT with ~12% total‑cholesterol and ~17% triglyceride reductions over 4 months.
- Therapy with garlic: results of a placebo-controlled, double-blind study
PubMed ID: 2083173
4‑month DBPC trial lowered cholesterol, triglycerides and BP—supports CV health.
- Can garlic reduce levels of serum lipids? A controlled clinical study
PubMed ID: 8506890
12‑week randomized trial lowered total cholesterol and LDL—supports heart health.
- Effect of garlic on platelet aggregation in patients with increased risk of juvenile ischaemic attack
PubMed ID: 8299665
Marked inhibition of platelet aggregation in at‑risk subjects—anti‑thrombotic CV mechanism.
- A double-blind crossover study in moderately hypercholesterolemic men that compared the effect of aged garlic extract and placebo administration on blood lipids
PubMed ID: 8942410
Aged garlic extract reduced total cholesterol, LDL and systolic BP in crossover trial.
- The antiatherosclerotic effect of Allium sativum
PubMed ID: 10381297
4‑year RCT showed slowed/reversed carotid/femoral plaque progression—strong anti‑atherosclerotic evidence.
- [Hypotensive effect of long-acting garlic tablets allicor (a double-blind placebo-controlled trial)]
PubMed ID: 11980131
RCT showed systolic/diastolic BP lowering in mild–moderate hypertension, a direct cardiovascular benefit.
- Effects of garlic on dyslipidemia in patients with type 2 diabetes mellitus
PubMed ID: 16320801
Modest improvements in total/LDL/HDL in type 2 diabetics, which are cardioprotective risk-factor changes.
- [Reduction of cardiovascular risk in primary prophylaxy of coronary heart disease]
PubMed ID: 15941145
Prolonged Allicor reduced modeled 10-year CHD risk and improved lipids in a randomized trial.
- [Allicor efficacy in lowering the risk of ischemic heart disease in primary prophylaxis]
PubMed ID: 16514811
Year-long Allicor trial lowered modeled ischemic heart disease risk and total/LDL cholesterol.
- Effects of anethum graveolens and garlic on lipid profile in hyperlipidemic patients
PubMed ID: 17328819
Enteric-coated garlic produced clinically meaningful cholesterol improvements over 6 weeks, supporting cardiovascular risk reduction.
- [Use of allicor to lower the risk of myocardial infarction]
PubMed ID: 17523399
Allicor lowered LDL and reduced calculated 10-year MI/sudden-death risk in CAD patients over 12 months.
- Lipid-lowering effects of time-released garlic powder tablets in double-blinded placebo-controlled randomized study
PubMed ID: 19060427
Human RCT showed reductions in total/LDL and increase in HDL—cardiovascular risk factors improved.
- Time-released garlic powder tablets lower systolic and diastolic blood pressure in men with mild and moderate arterial hypertension
PubMed ID: 19390538
RCT in hypertensive men showed clinically meaningful BP reductions, supporting cardiovascular benefit.
- Aged garlic extract lowers blood pressure in patients with treated but uncontrolled hypertension: a randomised controlled trial
PubMed ID: 20594781
Aged garlic extract produced clinically meaningful systolic BP reductions in uncontrolled hypertensives.
- The effects of time-released garlic powder tablets on multifunctional cardiovascular risk in patients with coronary artery disease
PubMed ID: 20958974
Time‑released garlic lowered LDL/total cholesterol and reduced 10‑year CV prognostic risk in coronary patients.
- Reduction of serum lipids by the intake of the extract of garlic fermented with Monascus pilosus: a randomized, double-blind, placebo-controlled clinical trial
PubMed ID: 22041543
Fermented garlic modestly lowered total and LDL cholesterol in humans—cardiometabolic benefit.
- Aged garlic extract reduces blood pressure in hypertensives: a dose-response trial
PubMed ID: 23169470
Dose–response RCT found ~11.8 mmHg systolic BP reduction—relevant to cardiovascular health.
- Differential responses of endothelial integrity upon the intake of microencapsulated garlic, tomato extract or a mixture: a single-intake, randomized, double-blind, placebo-controlled crossover trial
PubMed ID: 30280751
Single-dose biomarker changes in smokers (coagulation and vascular inflammation markers) suggest acute vascular effects.
- Garlic extract favorably modifies markers of endothelial function in obese patients -randomized double blind placebo-controlled nutritional intervention
PubMed ID: 29604599
3-month RCT in obese adults lowered arterial stiffness, hsCRP and LDL—direct cardiometabolic/vascular benefit.
- Aged garlic extract preserves cutaneous microcirculation in patients with increased risk for cardiovascular diseases: A double-blinded placebo-controlled study
PubMed ID: 31518044
1-year AGE trial increased skin microvascular perfusion in people at elevated CVD risk—supports vascular function.
- Effects of garlic powder supplementation on insulin resistance, oxidative stress, and body composition in patients with non-alcoholic fatty liver disease: A randomized controlled clinical trial
PubMed ID: 32507439
12-week trial in NAFLD improved insulin sensitivity and body composition—indirect benefit for cardiovascular risk.
- Effects of garlic powder supplementation on metabolic syndrome components, insulin resistance, fatty liver index, and appetite in subjects with metabolic syndrome: A randomized clinical trial
PubMed ID: 33974725
3-month RCT in metabolic syndrome improved multiple cardiometabolic risk factors (BP, lipids, waist) relevant to heart health.
- Successful improved peripheral tissue perfusion was seen in patients with atherosclerosis after 12 months of treatment with aged garlic extract
PubMed ID: 33590955
12-month RCT in coronary atherosclerosis patients improved endothelial-dependent responses and microvascular perfusion.
- Effects of Fermented Garlic Extract Containing Nitric Oxide Metabolites on Blood Flow in Healthy Participants: A Randomized Controlled Trial
PubMed ID: 36558397
Acute fermented-garlic study produced large, rapid BP reductions and increased carotid/cerebral/peripheral flow—strong haemodynamic effects.
- Garlic supplementation improves intestinal transit time, lipid accumulation product and cardiometabolic indices in subjects with metabolic syndrome: A randomized controlled trial
PubMed ID: 36721177
3-month RCT in metabolic-syndrome subjects improved intestinal transit and multiple cardiometabolic indices (LAP, CMI) relevant to heart health.
- LDL-Cholesterol-Lowering Effects of a Dietary Supplement Containing Onion and Garlic Extract Used in Healthy Volunteers
PubMed ID: 39203947
RDBPC trial (garlic+onion) reduced LDL/total cholesterol and oxidized‑LDL, favoring heart health.
- Randomized, double-blind clinical trial evaluating the impact of freeze-dried garlic extract capsules on blood pressure, lipid profile, and nitric oxide levels in individuals at risk for hypertension
PubMed ID: 39001718
Randomized trial showed BP lowering, lipid improvements and ↑NO—strong cardiovascular effects.
- Aged garlic extract, a modulator of cardiovascular risk factors: a dose-finding study on the effects of AGE on platelet functions
PubMed ID: 11238801
Aged garlic extract reduced platelet stickiness — plausible cardioprotective mechanism.
- Hypocholesterolemic effect of an enteric-coated garlic supplement
PubMed ID: 11444418
Enteric-coated garlic modestly lowered total and LDL cholesterol, which supports heart health.
- Aged garlic extract supplemented with B vitamins, folic acid and L-arginine retards the progression of subclinical atherosclerosis: a randomized clinical trial
PubMed ID: 19573556
Aged garlic + supplements reduced CAC progression and improved vascular reactivity (multi-ingredient trial).
- Effects of garlic on brachial endothelial function and capacity of plasma to mediate cholesterol efflux in patients with coronary artery disease
PubMed ID: 28554988
Improved endothelial function (FMD) and reduced hs-CRP in CAD patients after garlic tablets — direct vascular benefit.
- Anti-atherosclerotic therapy based on botanicals
PubMed ID: 23176379
Two-year RCT showing reduced carotid IMT and lowered LDL/serum atherogenicity with garlic powder (Allicor) — direct anti-atherosclerotic evidence.
- Reduction of blood lipid parameters by a 12-wk supplementation of aged black garlic: a randomized controlled trial
PubMed ID: 24976429
Aged black garlic raised HDL and lowered apoB in mild hypercholesterolemia — modestly favorable for heart health.
Cholesterol (25)
- Lipid-lowering effects of time-released garlic powder tablets in double-blinded placebo-controlled randomized study
PubMed ID: 19060427
Double‑blind RCT in hypercholesterolemic men showed significant decreases in total and LDL and increase in HDL.
- [Use of allicor to lower the risk of myocardial infarction]
PubMed ID: 17523399
Allicor lowered LDL by a clinically relevant margin in CAD patients over 12 months.
- Effects of anethum graveolens and garlic on lipid profile in hyperlipidemic patients
PubMed ID: 17328819
Six-week RCT showed significant decreases in total/LDL and increase in HDL with enteric-coated garlic.
- [Allicor efficacy in lowering the risk of ischemic heart disease in primary prophylaxis]
PubMed ID: 16514811
One-year Allicor trial produced significant reductions in total and LDL cholesterol (men > women).
- [Reduction of cardiovascular risk in primary prophylaxy of coronary heart disease]
PubMed ID: 15941145
Prolonged Allicor therapy improved lipids and reduced modeled 10-year CHD risk (randomized study).
- Effects of garlic on dyslipidemia in patients with type 2 diabetes mellitus
PubMed ID: 16320801
12-week RCT in type 2 diabetics showed meaningful decreases in total and LDL cholesterol and modest HDL rise.
- A double-blind crossover study in moderately hypercholesterolemic men that compared the effect of aged garlic extract and placebo administration on blood lipids
PubMed ID: 8942410
Aged garlic extract modestly lowered total cholesterol and LDL in crossover trial.
- Can garlic reduce levels of serum lipids? A controlled clinical study
PubMed ID: 8506890
12‑week DB trial produced significant decreases in total cholesterol and ~11% LDL reduction.
- Therapy with garlic: results of a placebo-controlled, double-blind study
PubMed ID: 2083173
4‑month DBPC trial lowered total cholesterol and triglycerides vs placebo.
- Treatment of hyperlipidaemia with garlic-powder tablets. Evidence from the German Association of General Practitioners' multicentric placebo-controlled double-blind study
PubMed ID: 2291748
Large multicenter RCT with ~12% total‑cholesterol and ~17% triglyceride reductions over 4 months.
- Effect of garlic and fish-oil supplementation on serum lipid and lipoprotein concentrations in hypercholesterolemic men
PubMed ID: 9022529
Randomized trial in hypercholesterolemic men showed clear decreases in total cholesterol and LDL.
- Efficacy of garlic (Allium sativum) on metabolic syndrome components in women with polycystic ovary syndrome: randomized controlled trial
PubMed ID: 40770379
RCT in PCOS/metabolic syndrome showed an ~8 mg/dL LDL reduction over 8 weeks vs placebo.
- Supplementation of garlic and coriander seed powder: Impact on body mass index, lipid profile and blood pressure of hyperlipidemic patients
PubMed ID: 30150192
Garlic (with coriander/mixture) produced within-group lipid improvements in hyperlipidemic patients over 60 days.
- Comparison of the efficacy and tolerance of a garlic preparation vs. bezafibrate
PubMed ID: 1288512
Garlic powder produced significant reductions in total cholesterol, LDL and triglycerides in hyperlipoproteinemia trial (comparable to bezafibrate).
- Reduction of blood lipid parameters by a 12-wk supplementation of aged black garlic: a randomized controlled trial
PubMed ID: 24976429
Aged black garlic modestly increased HDL and decreased apoB over 12 weeks in mild hypercholesterolemia (RCT).
- Anti-atherosclerotic therapy based on botanicals
PubMed ID: 23176379
Allicor garlic powder lowered LDL and serum atherogenicity over two years (RCT).
- Hypocholesterolemic effect of an enteric-coated garlic supplement
PubMed ID: 11444418
Enteric-coated garlic produced small but significant reductions in total and LDL cholesterol in humans.
- Effect of garlic powder supplementation on hepatic steatosis, liver enzymes and lipid profile in patients with non-alcoholic fatty liver disease: a double-blind randomised controlled clinical trial
PubMed ID: 32312333
NAFLD RCT showed significant decreases in triglycerides and improvements in lipids with garlic powder.
- Randomized, double-blind clinical trial evaluating the impact of freeze-dried garlic extract capsules on blood pressure, lipid profile, and nitric oxide levels in individuals at risk for hypertension
PubMed ID: 39001718
RDBPC trial in prehypertensive adults showed significant LDL and total cholesterol decreases.
- LDL-Cholesterol-Lowering Effects of a Dietary Supplement Containing Onion and Garlic Extract Used in Healthy Volunteers
PubMed ID: 39203947
Well‑conducted trial showed modest but consistent LDL and total cholesterol reductions (garlic+onion).
- Effects of garlic powder supplementation on metabolic syndrome components, insulin resistance, fatty liver index, and appetite in subjects with metabolic syndrome: A randomized clinical trial
PubMed ID: 33974725
3-month RCT in metabolic syndrome robustly improved HDL and triglycerides (and lowered other lipid-related indices).
- The effect of garlic (Allium sativum) supplementation on the lipid parameters and blood pressure levels in women with polycystic ovary syndrome: A randomized controlled trial
PubMed ID: 34496450
8-week RCT in PCOS women modestly lowered total and LDL cholesterol.
- Garlic extract favorably modifies markers of endothelial function in obese patients -randomized double blind placebo-controlled nutritional intervention
PubMed ID: 29604599
3-month randomized trial lowered LDL and improved lipid/inflammatory markers in obese adults.
- Reduction of serum lipids by the intake of the extract of garlic fermented with Monascus pilosus: a randomized, double-blind, placebo-controlled clinical trial
PubMed ID: 22041543
Randomized double‑blind trial showed significant decreases in total and LDL; triglyceride effect borderline.
- The effects of time-released garlic powder tablets on multifunctional cardiovascular risk in patients with coronary artery disease
PubMed ID: 20958974
12‑month randomized trial in coronary patients demonstrated significant LDL and total cholesterol reductions and lowered calculated risk.
Blood circulation (19)
- Beneficial effects of aged garlic extract and coenzyme Q10 on vascular elasticity and endothelial function: the FAITH randomized clinical trial
PubMed ID: 22858191
Aged garlic + CoQ10 improved pulse-wave velocity and digital endothelial function (direct circulation measures).
- The effect of aged garlic extract on the atherosclerotic process - a randomized double-blind placebo-controlled trial
PubMed ID: 32349742
AGE reduced systolic BP and CAC progression in a year-long RCT—favorable for overall circulation.
- Effects of garlic on brachial endothelial function and capacity of plasma to mediate cholesterol efflux in patients with coronary artery disease
PubMed ID: 28554988
Garlic tablets improved flow-mediated dilation (FMD) in post-angioplasty CAD patients — direct evidence of improved endothelial/vascular function.
- Anti-atherosclerotic therapy based on botanicals
PubMed ID: 23176379
Allicor reduced carotid IMT progression and serum atherogenicity — supports improved vascular health/circulation.
- Aged Garlic Extract Reduces Low Attenuation Plaque in Coronary Arteries of Patients with Metabolic Syndrome in a Prospective Randomized Double-Blind Study
PubMed ID: 26764322
AGE reduced vulnerable coronary plaque (LAP) in metabolic-syndrome patients — implies improved plaque stability/coronary circulation.
- Effect of Encapsulated Purple Garlic Oil on Microvascular Function and the Components of Metabolic Syndrome: A Randomized Placebo-Controlled Study-The ENDOTALLIUM Study
PubMed ID: 38892688
Purple garlic oil improved skin microvascular reactive hyperemia peak flow — improved microcirculation.
- Randomized, double-blind clinical trial evaluating the impact of freeze-dried garlic extract capsules on blood pressure, lipid profile, and nitric oxide levels in individuals at risk for hypertension
PubMed ID: 39001718
Significant increase in serum NO and BP reductions suggest improved endothelial function/circulation.
- Prospective, randomized, placebo-controlled, two-arm study to evaluate the efficacy of coadministration of garlic as a hydrogen sulfide donor and tadalafil in patients with erectile dysfunction not responding to tadalafil alone - A pilot study
PubMed ID: 39250620
Clinically meaningful improvement in erectile function (vascular outcome) after garlic juice in men on tadalafil.
- Evaluation of the Effect of Garlic Tablet as a Complementary Treatment for Patients with Diabetic Retinopathy
PubMed ID: 35875346
Adjunct garlic in DME lowered IOP and improved vision marginally—suggests ocular perfusion/pressure effects.
- Effects of Fermented Garlic Extract Containing Nitric Oxide Metabolites on Blood Flow in Healthy Participants: A Randomized Controlled Trial
PubMed ID: 36558397
Fermented garlic acutely increased carotid, cerebral and peripheral blood flow with large BP and perfusion changes.
- Successful improved peripheral tissue perfusion was seen in patients with atherosclerosis after 12 months of treatment with aged garlic extract
PubMed ID: 33590955
12-month RCT in coronary atherosclerosis patients significantly improved PORH and endothelial-dependent cutaneous perfusion (~21% treatment effect).
- Aged garlic extract preserves cutaneous microcirculation in patients with increased risk for cardiovascular diseases: A double-blinded placebo-controlled study
PubMed ID: 31518044
1-year AGE trial increased skin microvascular reactive hyperaemia vs placebo—improved microcirculatory function.
- Garlic extract favorably modifies markers of endothelial function in obese patients -randomized double blind placebo-controlled nutritional intervention
PubMed ID: 29604599
3-month RCT reduced arterial stiffness index (SI) and inflammatory markers—improves vascular function.
- Differential responses of endothelial integrity upon the intake of microencapsulated garlic, tomato extract or a mixture: a single-intake, randomized, double-blind, placebo-controlled crossover trial
PubMed ID: 30280751
Single-dose study altered prothrombin time and vascular-inflammation biomarkers in smokers—acute vascular biomarker changes.
- The role of garlic in hepatopulmonary syndrome: a randomized controlled trial
PubMed ID: 20352147
Improved arterial oxygenation and A–a gradient in hepatopulmonary syndrome indicates improved pulmonary circulation/oxygen transfer.
- The antiatherosclerotic effect of Allium sativum
PubMed ID: 10381297
Long‑term reduction in plaque progression implies improved arterial patency and circulatory function.
- Effect of garlic on platelet aggregation in patients with increased risk of juvenile ischaemic attack
PubMed ID: 8299665
Four weeks of garlic produced substantial reduction in platelet aggregation—improves microvascular flow/antithrombotic state.
- Effect of garlic powder tablet on carotid intima-media thickness in patients with coronary artery disease: a preliminary randomized controlled trial
PubMed ID: 25573347
Prevention of carotid thickening likely preserves arterial lumen and improves circulation.
- Aged garlic extract, a modulator of cardiovascular risk factors: a dose-finding study on the effects of AGE on platelet functions
PubMed ID: 11238801
Dose-ranging RCT: aged garlic extract reduced platelet adhesion and raised aggregation thresholds — direct circulation effect.
Blood pressure (15)
- The effect of garlic tablet on plasma lipids and platelet aggregation in nulliparous pregnants at high risk of preeclampsia
PubMed ID: 11788172
Trial in high‑risk pregnant women reported reduced incidence of hypertension (magnitude NR).
- A double-blind crossover study in moderately hypercholesterolemic men that compared the effect of aged garlic extract and placebo administration on blood lipids
PubMed ID: 8942410
Aged garlic extract modestly lowered systolic BP (~5.5%) in crossover trial.
- Therapy with garlic: results of a placebo-controlled, double-blind study
PubMed ID: 2083173
Four months of garlic powder lowered blood pressure compared with placebo.
- Hypertension and hyperlipidaemia: garlic helps in mild cases
PubMed ID: 2083170
DB RCT in mild hypertensives reduced diastolic BP by ~11–13 mmHg—strong BP effect.
- Efficacy of garlic (Allium sativum) on metabolic syndrome components in women with polycystic ovary syndrome: randomized controlled trial
PubMed ID: 40770379
8-week RCT showed ~5.5 mmHg lower SBP in garlic vs placebo in women with PCOS/metS.
- The effect of aged garlic extract on the atherosclerotic process - a randomized double-blind placebo-controlled trial
PubMed ID: 32349742
One-year AGE RCT reported an ~8 mmHg reduction in clinic systolic BP and lower CAC progression — strong BP-related outcome.
- Antihypertensive Effects of an Optimized Aged Garlic Extract in Subjects with Grade I Hypertension and Antihypertensive Drug Therapy: A Randomized, Triple-Blind Controlled Trial
PubMed ID: 37686723
Triple-blind RCT in medicated Grade I hypertensive patients showed small but detectable home BP reductions with aged black garlic over 12 weeks.
- Effects of an Optimized Aged Garlic Extract on Cardiovascular Disease Risk Factors in Moderate Hypercholesterolemic Subjects: A Randomized, Crossover, Double-Blind, Sustainedand Controlled Study
PubMed ID: 35276764
Standardized aged black garlic reduced diastolic blood pressure (~4.8 mmHg) in a randomized crossover trial — clinically meaningful BP effect.
- Aged garlic extract reduces blood pressure in hypertensives: a dose-response trial
PubMed ID: 23169470
Well‑designed dose–response RCT showed ~11.8 mmHg systolic reduction versus placebo at effective dose.
- Aged garlic extract lowers blood pressure in patients with treated but uncontrolled hypertension: a randomised controlled trial
PubMed ID: 20594781
Double‑blind RCT found ~10 mmHg SBP reduction in uncontrolled hypertensives with aged garlic extract.
- Time-released garlic powder tablets lower systolic and diastolic blood pressure in men with mild and moderate arterial hypertension
PubMed ID: 19390538
Double-blind RCT showed moderate, clinically meaningful systolic (~5–7 mmHg) and diastolic reductions with time-released garlic in mild-moderate hypertension.
- [Hypotensive effect of long-acting garlic tablets allicor (a double-blind placebo-controlled trial)]
PubMed ID: 11980131
Randomized placebo-controlled trial showed reductions in systolic and diastolic BP in mild–moderate hypertension.
- Randomized, double-blind clinical trial evaluating the impact of freeze-dried garlic extract capsules on blood pressure, lipid profile, and nitric oxide levels in individuals at risk for hypertension
PubMed ID: 39001718
Randomized double‑blind trial in prehypertensives showed statistically significant decreases in systolic and diastolic BP.
- Effects of Fermented Garlic Extract Containing Nitric Oxide Metabolites on Blood Flow in Healthy Participants: A Randomized Controlled Trial
PubMed ID: 36558397
Acute fermented-garlic induced large, rapid systolic/diastolic BP reductions (~−17/−12 mmHg) in healthy adults.
- Effects of garlic powder supplementation on metabolic syndrome components, insulin resistance, fatty liver index, and appetite in subjects with metabolic syndrome: A randomized clinical trial
PubMed ID: 33974725
3-month RCT lowered systolic BP by ~7.7 mmHg in metabolic-syndrome subjects—clinically meaningful sustained effect.
Inflammation (14)
- A randomized, double-blind, placebo-controlled clinical trial, evaluating the garlic supplement effects on some serum biomarkers of oxidative stress, and quality of life in women with rheumatoid arthritis
PubMed ID: 32159257
8-week RA RCT decreased MDA and improved symptoms—antioxidant/inflammatory improvements in autoimmune disease.
- Effects of garlic on brachial endothelial function and capacity of plasma to mediate cholesterol efflux in patients with coronary artery disease
PubMed ID: 28554988
hs-CRP decreased by ~29% in CAD patients after garlic tablets — direct anti-inflammatory signal.
- Relation of oxidative biomarkers, vascular dysfunction, and progression of coronary artery calcium
PubMed ID: 20152239
AGE trial sub-analysis linked improved oxidative biomarkers and vascular function to reduced coronary calcification — supports anti-inflammatory mechanism.
- Aged Garlic Extract Reduces Low Attenuation Plaque in Coronary Arteries of Patients with Metabolic Syndrome in a Prospective Randomized Double-Blind Study
PubMed ID: 26764322
Reduction in vulnerable coronary plaque with AGE implies reduced inflammatory plaque activity in metabolic-syndrome patients.
- The effect of aged garlic extract on the atherosclerotic process - a randomized double-blind placebo-controlled trial
PubMed ID: 32349742
AGE trial showed reduced IL-6 signal and less CAC progression — inflammatory marker improvement in a clinical RCT.
- Beneficial effects of aged garlic extract and coenzyme Q10 on vascular elasticity and endothelial function: the FAITH randomized clinical trial
PubMed ID: 22858191
AGE+CoQ10 lowered CRP and improved vascular markers over one year in intermediate-risk subjects.
- The effect of garlic tablet on pro-inflammatory cytokines in postmenopausal osteoporotic women: a randomized controlled clinical trial
PubMed ID: 23039014
RCT in postmenopausal osteoporotic women showed ~47% reduction in circulating TNF-α after one month of garlic tablets.
- Effect of Encapsulated Purple Garlic Oil on Microvascular Function and the Components of Metabolic Syndrome: A Randomized Placebo-Controlled Study-The ENDOTALLIUM Study
PubMed ID: 38892688
Purple garlic oil reduced hs-CRP and decreased metabolic-syndrome components over five weeks.
- The favorable effects of garlic intake on metabolic profiles, hs-CRP, biomarkers of oxidative stress and pregnancy outcomes in pregnant women at risk for pre-eclampsia: randomized, double-blind, placebo-controlled trial
PubMed ID: 25316559
In pregnant women at risk of pre‑eclampsia, garlic lowered hs‑CRP (inflammation marker) significantly vs placebo.
- Aged garlic extract supplementation modifies inflammation and immunity of adults with obesity: A randomized, double-blind, placebo-controlled clinical trial
PubMed ID: 29576354
6-week RCT reduced IL-6 and TNF-α in adults with obesity—direct anti-inflammatory biomarker reductions.
- The effect of a garlic supplement on the pro-inflammatory adipocytokines, resistin and tumor necrosis factor-alpha, and on pain severity, in overweight or obese women with knee osteoarthritis
PubMed ID: 30195882
12-week RCT in overweight women with knee OA lowered resistin and modestly reduced pain—anti-inflammatory signal with clinical effect.
- Garlic extract favorably modifies markers of endothelial function in obese patients -randomized double blind placebo-controlled nutritional intervention
PubMed ID: 29604599
3-month RCT reduced hsCRP and PAI-1 and improved arterial stiffness—clear anti-inflammatory and endothelial benefits.
- The effect of 12-week garlic supplementation on symptom relief in overweight or obese women with knee osteoarthritis
PubMed ID: 29790635
12-week trial improved stiffness in knee OA and showed symptom benefit consistent with reduced joint inflammation.
- Evaluating the effect of garlic extract on serum inflammatory markers of peritoneal dialysis patients: a randomized double-blind clinical trial study
PubMed ID: 30683061
8-week RCT in peritoneal dialysis patients produced significant CRP and ESR reductions.
Antimicrobial (13)
- The Efficacy of Aged Garlic Extract on Gingivitis - A Randomized Clinical Trial
PubMed ID: 30211991
4-month AGE reduced gum inflammation and bleeding—could reflect antimicrobial or anti-inflammatory effects in the oral cavity.
- Comparative evaluation of garlic extract mouthwash and chlorhexidine mouthwash on salivary Streptococcus mutans count - an in vitro study
PubMed ID: 21180674
7-day RCT: garlic extract mouthwash reduced Streptococcus mutans more than placebo and numerically more than chlorhexidine.
- [Study of the antioxidant drug "Karinat" in patients with chronic atrophic gastritis]
PubMed ID: 15088527
Combined antioxidant/garlic tablet inhibited H. pylori infection more than placebo in chronic atrophic gastritis (multi-ingredient study).
- Comparative evaluation of the antibacterial effect of Allium sativum, calcium hydroxide and their combination as intracanal medicaments in infected mature anterior teeth: A randomized clinical trial
PubMed ID: 35852013
Randomized clinical dental trial found garlic extract inside root canals reduced Enterococcus faecalis and Streptococcus species more effectively than calcium hydroxide—strong antimicrobial evidence in situ.
- Ajoene in the topical short-term treatment of tinea cruris and tinea corporis in humans. Randomized comparative study with terbinafine
PubMed ID: 10417874
Topical ajoene cured tinea corporis/cruris with efficacy similar to terbinafine (strong topical antifungal evidence).
- Efficacy of ajoene in the treatment of tinea pedis: a double-blind and comparative study with terbinafine
PubMed ID: 11050588
Topical 1% ajoene produced high mycologic cure rates for tinea pedis comparable or superior to terbinafine.
- <em>Allium Sativum</em> Oil as an Alternative Non-Vital Pulpotomy Medicament in Primary Teeth - A Randomised Controlled Trial
PubMed ID: 38462859
Allium sativum oil reduced bacterial counts comparably to formocresol in pulpotomy (local antibacterial effect).
- Antimicrobial activity of garlic, tea tree oil, and chlorhexidine against oral microorganisms
PubMed ID: 12553397
Garlic mouth rinse reduced mutans streptococci in a randomized trial (small sample, tolerability issues).
- Efficacy of garlic paste in oral candidiasis
PubMed ID: 15970035
Topical garlic paste was about as effective as clotrimazole for oral candidiasis (small RCT).
- Preventing airborne infection with an intranasal cellulose powder formulation (Nasaleze travel)
PubMed ID: 18029341
Intranasal powdered garlic extract markedly reduced airborne infections in a randomized blinded trial — strong antimicrobial/anti-infective signal in situ.
- Comparison of therapeutic effect of aqueous extract of garlic and nystatin mouthwash in denture stomatitis
PubMed ID: 22126338
Garlic mouthwash improved denture‑related oral inflammation nearly as well as nystatin—antifungal/antimicrobial oral application.
- Evaluation of TNF-α serum level in patients with recalcitrant multiple common warts, treated by lipid garlic extract
PubMed ID: 24910383
Topical lipid garlic extract achieved high cure rates for recalcitrant common warts in an RCT—strong topical antimicrobial/antiviral effect.
- Comparison of the therapeutic effects of Garcin(®) and fluconazole on Candida vaginitis
PubMed ID: 26512149
Randomized trial: oral garlic tablets improved symptoms and microbiological measures of Candida vaginitis versus baseline (clinical antimicrobial activity).
Immune support (9)
- [Study of the antioxidant drug "Karinat" in patients with chronic atrophic gastritis]
PubMed ID: 15088527
Combined antioxidant/garlic tablet inhibited H. pylori and improved gastric mucosa, indicating antimicrobial/immune-related benefit in the stomach (multi-ingredient).
- Preventing the common cold with a garlic supplement: a double-blind, placebo-controlled survey
PubMed ID: 11697022
Large double-blind RCT showed fewer colds and shorter illness duration with an allicin-containing garlic supplement.
- [Effect of long-acting garlic tablets "allicor" on the incidence of acute respiratory viral infections in children]
PubMed ID: 12718222
Substantial reductions in acute respiratory disease incidence suggest immune-enhancing effects in children.
- Aged garlic extract prevents a decline of NK cell number and activity in patients with advanced cancer
PubMed ID: 16484572
Aged garlic extract increased NK cell number and activity in advanced cancer patients (randomized trial).
- Preventing airborne infection with an intranasal cellulose powder formulation (Nasaleze travel)
PubMed ID: 18029341
Intranasal garlic extract markedly reduced infections and infection-days in travelers — strong evidence of protective effect vs airborne pathogens.
- Supplementation with aged garlic extract improves both NK and γδ-T cell function and reduces the severity of cold and flu symptoms: a randomized, double-blind, placebo-controlled nutrition intervention
PubMed ID: 22280901
AGE increased γδ‑T and NK cell proliferation and markedly reduced cold/flu symptom severity and duration in an RCT.
- Aged Garlic Extract Modifies Human Immunity
PubMed ID: 26764332
90-day AGE RCT increased γδ-T and NK cell activation/proliferation and reduced cold/flu symptom severity—strong immune support evidence.
- Aged garlic extract supplementation modifies inflammation and immunity of adults with obesity: A randomized, double-blind, placebo-controlled clinical trial
PubMed ID: 29576354
6-week AGE RCT increased γδ-T cells and reduced IL-6 and TNF-α in adults with obesity—immune-modulatory effects.
- The Efficacy of Aged Garlic Extract on Gingivitis - A Randomized Clinical Trial
PubMed ID: 30211991
4-month AGE reduced gum inflammation/bleeding—localized immune/mucosal benefit consistent with immune modulation.
Antioxidant (8)
- A randomized, double-blind, placebo-controlled clinical trial, evaluating the garlic supplement effects on some serum biomarkers of oxidative stress, and quality of life in women with rheumatoid arthritis
PubMed ID: 32159257
8-week RCT in women with RA increased TAC and decreased MDA (direct antioxidant outcomes).
- LDL-Cholesterol-Lowering Effects of a Dietary Supplement Containing Onion and Garlic Extract Used in Healthy Volunteers
PubMed ID: 39203947
Substantial reductions in oxidized‑LDL indicate antioxidant/anti‑oxidative effects (garlic+onion product).
- Effects of garlic powder supplementation on metabolic syndrome components, insulin resistance, fatty liver index, and appetite in subjects with metabolic syndrome: A randomized clinical trial
PubMed ID: 33974725
Metabolic-syndrome trial improved multiple metabolic markers; antioxidant outcome was not the primary endpoint but changes suggest oxidative benefits.
- Relation of oxidative biomarkers, vascular dysfunction, and progression of coronary artery calcium
PubMed ID: 20152239
AGE-related changes in oxidative biomarkers correlated with less coronary calcification — evidence linking garlic-related antioxidant effects to outcomes.
- Long-term garlic or micronutrient supplementation, but not anti-Helicobacter pylori therapy, increases serum folate or glutathione without affecting serum vitamin B-12 or homocysteine in a rural Chinese population
PubMed ID: 19056661
Long-term supplementation raised serum folate and (with vitamins/selenium) increased glutathione — supports antioxidant capacity.
- The favorable effects of garlic intake on metabolic profiles, hs-CRP, biomarkers of oxidative stress and pregnancy outcomes in pregnant women at risk for pre-eclampsia: randomized, double-blind, placebo-controlled trial
PubMed ID: 25316559
In pregnant women at risk for pre‑eclampsia, garlic tablets significantly increased glutathione (GSH) vs placebo.
- Garlic extract favorably modifies markers of endothelial function in obese patients -randomized double blind placebo-controlled nutritional intervention
PubMed ID: 29604599
3-month RCT reported increased total antioxidant status alongside reductions in inflammation and LDL.
- Effects of garlic powder supplementation on insulin resistance, oxidative stress, and body composition in patients with non-alcoholic fatty liver disease: A randomized controlled clinical trial
PubMed ID: 32507439
12-week RCT in NAFLD increased SOD and total antioxidant capacity and reduced MDA (clear antioxidant marker changes).
Respiratory comfort (6)
- [Influence of garlic moxibustion on the therapeutic effect in re-treatment patients of tuberculosis]
PubMed ID: 19186714
Garlic moxibustion added to TB treatment improved radiographic and sputum outcomes—clinical respiratory adjunct (combined therapy).
- [Effect of long-acting garlic tablets "allicor" on the incidence of acute respiratory viral infections in children]
PubMed ID: 12718222
Long-acting garlic tablets substantially reduced acute respiratory disease rates and improved a general health index in children.
- Aged Garlic Extract Modifies Human Immunity
PubMed ID: 26764332
90-day AGE RCT reduced cold/flu symptom severity and decreased days functionally impaired—clinical respiratory symptom benefit.
- Supplementation with aged garlic extract improves both NK and γδ-T cell function and reduces the severity of cold and flu symptoms: a randomized, double-blind, placebo-controlled nutrition intervention
PubMed ID: 22280901
AGED garlic extract greatly reduced severity and duration of cold/flu symptoms in healthy adults (respiratory illness benefit).
- The role of garlic in hepatopulmonary syndrome: a randomized controlled trial
PubMed ID: 20352147
Oral garlic markedly improved PaO2, A–a gradient and achieved high reversal of hepatopulmonary syndrome vs placebo.
- Preventing airborne infection with an intranasal cellulose powder formulation (Nasaleze travel)
PubMed ID: 18029341
Intranasal powdered garlic extract markedly reduced number of infections and infection-days in travelers (randomized blinded study).
Cold/flu relief (5)
- [Effect of long-acting garlic tablets "allicor" on the incidence of acute respiratory viral infections in children]
PubMed ID: 12718222
Reduced acute respiratory disease rates in children, implying fewer/less severe cold/flu episodes.
- Preventing airborne infection with an intranasal cellulose powder formulation (Nasaleze travel)
PubMed ID: 18029341
Intranasal garlic extract reduced infections and days ill in travelers, directly relevant to easing cold/flu burden.
- Supplementation with aged garlic extract improves both NK and γδ-T cell function and reduces the severity of cold and flu symptoms: a randomized, double-blind, placebo-controlled nutrition intervention
PubMed ID: 22280901
Aged garlic extract greatly reduced cold/flu symptom severity, days with suboptimal function and symptoms in a randomized trial.
- Aged Garlic Extract Modifies Human Immunity
PubMed ID: 26764332
90-day AGE RCT reduced cold/flu symptom severity and decreased days of functional impairment despite unchanged incidence—direct clinical benefit.
- Preventing the common cold with a garlic supplement: a double-blind, placebo-controlled survey
PubMed ID: 11697022
Allicin-containing garlic supplement RCT markedly reduced cold incidence, days ill, and duration per infection.
Weight management (6)
- Garlic supplementation improves intestinal transit time, lipid accumulation product and cardiometabolic indices in subjects with metabolic syndrome: A randomized controlled trial
PubMed ID: 36721177
3-month RCT improved lipid accumulation product and other cardiometabolic indices that correlate with central adiposity.
- Effects of garlic powder supplementation on insulin resistance, oxidative stress, and body composition in patients with non-alcoholic fatty liver disease: A randomized controlled clinical trial
PubMed ID: 32507439
12-week NAFLD RCT reduced waist circumference and body fat% and improved insulin sensitivity—meaningful body-composition effects.
- Effect of Raw Crushed Garlic (Allium sativum L.) on Components of Metabolic Syndrome
PubMed ID: 28956671
Small short-term study reported significant waist circumference reduction after 4 weeks of raw crushed garlic.
- Effects of garlic powder supplementation on metabolic syndrome components, insulin resistance, fatty liver index, and appetite in subjects with metabolic syndrome: A randomized clinical trial
PubMed ID: 33974725
3-month RCT reduced waist circumference and improved multiple metabolic-syndrome components relevant to weight/abdominal fat.
- Efficacy of garlic (Allium sativum) on metabolic syndrome components in women with polycystic ovary syndrome: randomized controlled trial
PubMed ID: 40770379
RCT reported ~2.7 kg greater weight loss in garlic vs placebo over 8 weeks in PCOS/metabolic syndrome patients.
- Supplementation of garlic and coriander seed powder: Impact on body mass index, lipid profile and blood pressure of hyperlipidemic patients
PubMed ID: 30150192
Garlic-containing interventions showed within-group BMI improvement over 60 days in hyperlipidemic patients.
Skin health (5)
- Aged garlic extract preserves cutaneous microcirculation in patients with increased risk for cardiovascular diseases: A double-blinded placebo-controlled study
PubMed ID: 31518044
1-year AGE RCT increased skin microvascular blood flow (reactive hyperaemia) in at-risk participants—supports skin perfusion.
- Successful improved peripheral tissue perfusion was seen in patients with atherosclerosis after 12 months of treatment with aged garlic extract
PubMed ID: 33590955
12-month RCT improved peripheral microcirculation and endothelial responses—likely beneficial for skin perfusion/healing.
- Evaluation of TNF-α serum level in patients with recalcitrant multiple common warts, treated by lipid garlic extract
PubMed ID: 24910383
Topical lipid garlic extract produced high cure rates for recalcitrant common warts in an RCT (skin outcome).
- Efficacy of ajoene in the treatment of tinea pedis: a double-blind and comparative study with terbinafine
PubMed ID: 11050588
Topical 1% ajoene was highly effective for tinea pedis (skin fungal infection) in a randomized trial.
- Ajoene in the topical short-term treatment of tinea cruris and tinea corporis in humans. Randomized comparative study with terbinafine
PubMed ID: 10417874
Topical ajoene cured tinea corporis/cruris at rates comparable to terbinafine (clinical skin benefit).
Blood sugar (5)
- Effects of garlic powder supplementation on metabolic syndrome components, insulin resistance, fatty liver index, and appetite in subjects with metabolic syndrome: A randomized clinical trial
PubMed ID: 33974725
3-month metabolic-syndrome RCT lowered insulin and improved fatty liver index—meaningful glycemic/metabolic improvements.
- Effects of garlic powder supplementation on insulin resistance, oxidative stress, and body composition in patients with non-alcoholic fatty liver disease: A randomized controlled clinical trial
PubMed ID: 32507439
12-week RCT in NAFLD patients produced significant decreases in fasting insulin and HOMA-IR—strong evidence for improved insulin sensitivity.
- Garlic (Allium sativum) supplementation with standard antidiabetic agent provides better diabetic control in type 2 diabetes patients
PubMed ID: 21959822
Randomized trial adding garlic to metformin yielded a small but statistically significant reduction in fasting blood glucose.
- Metabolic effects of time-released garlic powder tablets in type 2 diabetes mellitus: the results of double-blinded placebo-controlled study
PubMed ID: 17823766
Time-released garlic tablets lowered fasting glucose and fructosamine in a 4-week double-blind trial in type 2 diabetics (short duration but positive).
- Garlic supplementation improves intestinal transit time, lipid accumulation product and cardiometabolic indices in subjects with metabolic syndrome: A randomized controlled trial
PubMed ID: 36721177
3-month RCT improved several cardiometabolic indices; insulin/glucose effects reported as part of broader metabolic improvements.
Detoxification (4)
- Comparison of therapeutic effects of garlic and d-Penicillamine in patients with chronic occupational lead poisoning
PubMed ID: 22151785
Randomized trial: garlic capsules lowered blood lead levels and improved related symptoms comparably to d‑penicillamine.
- Long-term garlic or micronutrient supplementation, but not anti-Helicobacter pylori therapy, increases serum folate or glutathione without affecting serum vitamin B-12 or homocysteine in a rural Chinese population
PubMed ID: 19056661
Long-term supplementation (with vitamin/selenium context) increased glutathione — central to detoxification pathways.
- Effect of garlic powder supplementation on hepatic steatosis, liver enzymes and lipid profile in patients with non-alcoholic fatty liver disease: a double-blind randomised controlled clinical trial
PubMed ID: 32312333
Well-conducted RCT in NAFLD showed significant reductions in hepatic steatosis and ALT — direct liver support evidence.
- Efficacy and safety of fermented garlic extract on hepatic function in adults with elevated serum gamma-glutamyl transpeptidase levels: a double-blind, randomized, placebo-controlled trial
PubMed ID: 27743130
Fermented garlic extract modestly improved liver enzymes (ALT) in adults with mildly elevated GGT.
Digestive support (2)
- [Study of the antioxidant drug "Karinat" in patients with chronic atrophic gastritis]
PubMed ID: 15088527
Combined antioxidant/garlic tablet improved gastric symptoms and endoscopic mucosal markers in chronic atrophic gastritis (multi-ingredient trial).
- Garlic supplementation improves intestinal transit time, lipid accumulation product and cardiometabolic indices in subjects with metabolic syndrome: A randomized controlled trial
PubMed ID: 36721177
3-month RCT showed improved intestinal transit time in metabolic-syndrome subjects (direct digestive benefit).
Gut health (1)
- [Study of the antioxidant drug "Karinat" in patients with chronic atrophic gastritis]
PubMed ID: 15088527
Combined antioxidant/garlic tablet inhibited H. pylori and improved gastric mucosa in chronic atrophic gastritis — direct effect on a gastric pathogen (multi-ingredient trial).
Mental clarity (1)
- Effects of Fermented Garlic Extract Containing Nitric Oxide Metabolites on Blood Flow in Healthy Participants: A Randomized Controlled Trial
PubMed ID: 36558397
Acute fermented-garlic increased regional cerebral blood flow—physiologic basis for potential short-term cognitive/clarity effects.
Similar by evidence
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Products with Garlic
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Being studied right now
Recruiting clinical trials registered on ClinicalTrials.gov. A trial in progress has no result yet — this is what the field is asking, not what it found.