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Appetite regulation

How steady hunger is across a day, rather than how strong it is at one moment. Trials track hunger and fullness ratings at intervals and compare how much is eaten at the next meal.

21 supplements analyzed and ranked by clinical evidence.

Supplements21

Supplement Evidence

Alfalfa
Strong

Intake↑, appetite

Hormones↓; intake↑

Rumen pH↑, intake↑

108 studies·11 benefits
Zinc
Strong

↑ Intake, appetite +

↓ Nausea/illness, +

1804 studies·17 benefits
Prebiotics
Strong

Appetite ↓ hunger, +fullness

Glucose/insulin ↓, PYY/GLP-1 ↑

Energy intake ↓

769 studies·15 benefits
Tryptophan
Moderate

↑ satiety hormones; ↓ intake

Trp/LNAA shifts; appetite changes

5-HTP/Trp ↓ hunger

413 studies·13 benefits
Hops
Moderate

↓ hunger, ↑ fullness

↓ food intake ~17%

48 studies·9 benefits
Alanine
Weak

↑ Alanine, satiety

-5.57% bodyweight, appetite

3028 studies·18 benefits
Isoleucine
Weak

Amino acids ↓ hunger

Amino acids ↓ intake

Amino acids ↑ satiety

86 studies·13 benefits
Green Tea Extract
Weak

↓weight/waist

↑GLP-1, ↓ghrelin

244 studies·17 benefits
Vitamin B9
Weak

↓ Insulin/hunger peak

+1.7 appetite score

↑ reported appetite/energy

2758 studies·14 benefits
Cinchona
Weak

Satiety/CCK ↑

Weight/fat loss -11%

9 studies·5 benefits
Acacia Fiber
Weak

Satiety↑ hunger↓

Glucose −5%

15 studies·6 benefits
Damiana
Weak

Slower emptying, −17% intake

Lower hunger, −5.1 kg

6 studies·5 benefits
Alanylglutamine
Weak

Mucositis, feeding tubes -53%

Weight loss, steroids reduced

54 studies·12 benefits
Oat Straw
Weak

+feed intake

+growth

1 study·3 benefits
Black Pepper
Weak

Appetite↓, fullness↑

Nausea↓, pulse↓

37 studies·13 benefits
Gentian
Weak

Weight/fat loss

Satiety +4.2

32 studies·2 benefits
Thiamine
Weak

↑ appetite, intake, weight

↓ fatigue, +10 mg/day

296 studies·23 benefits
Moringa
Weak

Lower hunger; glucose -

Better eating patterns

25 studies·12 benefits
Wormwood
Weak

Anorexia score ↓

Albumin/Hb unchanged

47 studies·9 benefits
Niacin
Weak

Leptin +2.38; FFA ↓

Leptin +26.8%; HOMA +42%

↑ appetite, +weight

+B3, +B12,D

859 studies·20 benefits
Iodine
Weak

PYY satiety +56%

Triglycerides -28%

1602 studies·17 benefits