Coptis
13 benefits mapped to clinical evidence across supplements.
Dose per serving from research
6 study groups in 1 study say how much Coptis participants took a day.
These are the doses the studies gave. They are not a recommendation.
Most common: 25 g to 50 g, 83% of 6 study groups.
| Daily dose | Study groups |
|---|---|
| 10 g or less | 1 |
| 10 g to 25 g | 0 |
| 25 g to 50 g | 5 |
Benefit Evidence
Research sources
Blood sugar (4)
- Chinese herbal medicine for obesity: a randomized, double-blinded, multicenter, prospective trial
PubMed ID: 25406653
Obesity RCT: formula with Coptis led to weight loss and improved insulin‑resistance index, consistent with better glycemic/metabolic control.
- The Clinical Efficacy of Gegen Qinlian Decoction in Treating Type 2 Diabetes is Positively Correlated with the Dose of Coptidis rhizoma: Three Randomized, Doubleblind, Dose-Parallel Controlled Clinical Trials
PubMed ID: 39650851
Dose‑parallel randomized trials show a clear dose–response: higher Coptis (berberine) doses produced significantly greater HbA1c and postprandial glucose reductions.
- Improving insulin resistance with traditional Chinese medicine in type 2 diabetic patients
PubMed ID: 19728183
Randomized trial with a TCM formula including Coptis improved insulin‑mediated glucose disposal by 24% in newly diagnosed T2D.
- [Effect of Tangyikang in improving the function of pancreatic islet beta cells in patients with latent autoimmune diabetes mellitus in adults]
PubMed ID: 19123322
In LADA patients, adding a Coptis‑containing formula improved a beta‑cell function index and reduced insulin dose requirements over 3 months.
Energy & Fatigue (1)
- The Clinical Efficacy of Gegen Qinlian Decoction in Treating Type 2 Diabetes is Positively Correlated with the Dose of Coptidis rhizoma: Three Randomized, Doubleblind, Dose-Parallel Controlled Clinical Trials
PubMed ID: 39650851
Dose‑related HbA1c and postprandial glucose reductions suggest more stable glycemic control, which can translate to steadier energy.
Blood circulation (1)
- Prospective multicenter clinical trial of Chinese herbal formula JZQG (Jiangzhuoqinggan) for hypertension
PubMed ID: 23336505
Blood‑pressure lowering and reduced waist circumference imply improved hemodynamic/metabolic circulation parameters versus comparator (multi‑herb formula).
Heart health (1)
- Prospective multicenter clinical trial of Chinese herbal formula JZQG (Jiangzhuoqinggan) for hypertension
PubMed ID: 23336505
Large multicenter trial: a Coptis‑containing formula lowered clinic and 24‑h ambulatory blood pressure comparably to irbesartan — clinically relevant cardiovascular benefit (multi‑herb).
Respiratory comfort (1)
- Efficacy and safety of mixture of ivy leaf extract and coptidis rhizome in the treatment of acute bronchitis: multicenter, randomized, double-blinded, active-controlled, parallel, therapeutic confirmatory clinical trial
PubMed ID: 38889376
Well‑powered randomized double‑blind trial: ivy‑leaf + Coptis rhizome syrup provided non‑inferior symptomatic relief in acute bronchitis over 7 days.
Metabolism (1)
- Chinese herbal medicine for obesity: a randomized, double-blinded, multicenter, prospective trial
PubMed ID: 25406653
Large RCT in obese subjects with ~1.7 kg greater weight loss and improved insulin resistance — consistent with increased metabolic/endocrine activity.
Weight management (1)
- Chinese herbal medicine for obesity: a randomized, double-blinded, multicenter, prospective trial
PubMed ID: 25406653
Large 24‑week RCT in 140 obese subjects: TCM formula containing Coptis produced ~1.7 kg greater weight loss versus low‑dose control (p<0.01).
Digestive support (1)
- [Active Crohn's disease treated with acupuncture and moxibustion:a randomized controlled trial]
PubMed ID: 29231405
Randomized trial in Crohn's disease: Coptis‑containing herb‑partition moxibustion improved abdominal pain, diarrhea and appetite compared with control.
Gut health (1)
- [Active Crohn's disease treated with acupuncture and moxibustion:a randomized controlled trial]
PubMed ID: 29231405
Improvement in Crohn's disease symptom scores (diarrhea, abdominal pain, anorexia) supports a role in balancing gut symptoms (multi‑component intervention).
Immune support (1)
- [Effect of Tangyikang in improving the function of pancreatic islet beta cells in patients with latent autoimmune diabetes mellitus in adults]
PubMed ID: 19123322
LADA trial including Coptis changed Th1/Th2 cytokines (↓IFN‑γ, ↑IL‑4) and improved beta‑cell index, indicating immunomodulatory effects in humans (multi‑herb).
Acne (1)
- [Effect of moxibustion on plaque psoriasis complicated with obesity]
PubMed ID: 37429654
Randomized trial in plaque psoriasis found greater PASI improvement when topical Coptis was used with moxibustion, directly supporting skin benefit.
Inflammation (1)
- [Effect of moxibustion on plaque psoriasis complicated with obesity]
PubMed ID: 37429654
Psoriasis trial showed greater clinical improvement (PASI) with Coptis ointment + moxibustion, consistent with anti‑inflammatory effects in skin disease.
Oral health (1)
- [The clinical study on the adjunctive effects of aqueous extract from coptis root for the treatment of chronic periodontitis]
PubMed ID: 15349657
Randomized clinical study: placing a Coptis extract membrane after scaling improved probing depth, attachment and bleeding on probing vs controls over 7 weeks.
Similar by evidence
Supplements the same benefits carry qualifying findings for — a fact about the evidence graph, not a recommendation to swap.
Products with Coptis
Search all41 products whose verified label declares Coptis — not every bottle that mentions it in a title.