supp.fit

Acne

Spots, blackheads and inflamed pores, usually on the face, back or chest. Trials count lesions before and after, and separate inflammatory lesions from non-inflammatory ones because the two respond differently.

9 supplements analyzed and ranked by clinical evidence.

Supplements9

Supplement Evidence

Prebiotics
Strong

Eczema severity −18

Allergy incidence −57%

Acne lesions −7

769 studies·15 benefits
Glutathione
Strong

Antioxidants↑, acne?

Lipid peroxidation↓

1244 studies·19 benefits
Inositol
Moderate

↓ insulin, androgens

+ acne score improvement

+86% ovulation

270 studies·17 benefits
Tea Tree Oil
Moderate

Lesions ↓38%

Severity, lesions

47 studies·9 benefits
Lactoferrin
Moderate

Inflammatory lesions -39%

Total lesions -23%

Sebum -31%

188 studies·15 benefits
Biotin
Weak

FPD -16.5

Growth improved

Lesions reduced

73 studies·14 benefits
Betaine
Weak

Less irritation, no acne change

AE −4.2 pp, no acne

118 studies·16 benefits
Chlorophyll
Weak

Lesions, sebum down

Clearance +67%

13 studies·10 benefits
Coptis
Weak

Acne severity ↓

Metabolic markers ↓

9 studies·13 benefits