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Salacia Reticulata

10 benefits mapped to clinical evidence across supplements.

Dose per serving from research

9 study groups in 5 studies say how much Salacia Reticulata participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 250 mg to 500 mg, 56% of 9 study groups.

Daily doseStudy groups
100 mg to 250 mg
2
250 mg to 500 mg
5
500 mg to 1 g
1
1 g to 2.5 g
1

See every study group

Benefit Evidence

Blood sugar
Moderate

Post-meal glucose ↓

HbA1c/FBS ↓

376 people

Glucose/insulin AUC ↓

Breath hydrogen ↑

152 people

Kidney stabilization, IL-6↓

CRP/IL-6↓, creatinine clearance stable

90 people

IL-6/CRP ↓

Homocysteine ↓

90 people

Lipids/glucose LDL, FBS

Inflammation/kidney TG −23.66%

60 people

LDL↓ (significant)

Triglycerides↓ 17-24%

60 people

Lipids, glucose −23.7%

Inflammation, kidney stability

60 people

Lower HbA1c, less fatigue

−0.36 HbA1c, dose↓

51 people

Weight loss −5.3 kg

Body fat −4.5%

40 people

T-cells +0.24

Bifidobacterium +29%

Immune age -2y

30 people

Research sources

Blood sugar (7)
  1. Appetite and Gut Hormones Response to a Putative α-Glucosidase Inhibitor, Salacia Chinensis, in Overweight/Obese Adults: A Double Blind Randomized Controlled Trial

    PubMed ID: 28805670

    Attenuated postprandial glucose/insulin AUC and increased breath/enteric‑peptide responses support a sugar‑absorption limiting effect.

  2. A double blind randomised placebo controlled cross over study of a herbal preparation containing Salacia reticulata in the treatment of type 2 diabetes

    PubMed ID: 15707755

    Randomized double‑blind crossover in T2D over 3 months showed clinically meaningful HbA1c reduction (strong clinical evidence).

  3. Effects of a medical food containing an herbal alpha-glucosidase inhibitor on postprandial glycemia and insulinemia in healthy adults

    PubMed ID: 15635348

    Dose–response trial increased breath hydrogen and lowered insulin (and trended to lower glucose)—supports reduced carbohydrate digestion/absorption.

  4. Extract of Salacia oblonga lowers acute glycemia in patients with type 2 diabetes

    PubMed ID: 17616771

    Dose‑dependent reductions in postprandial glucose and insulin in T2D patients—strong acute glycemic evidence.

  5. Effects of a nutritional supplement containing Salacia oblonga extract and insulinogenic amino acids on postprandial glycemia, insulinemia, and breath hydrogen responses in healthy adults

    PubMed ID: 15975493

    Healthy‑adult crossover showed ~25% lower postprandial glucose AUC and a large breath‑hydrogen rise—strong evidence of α‑glucosidase inhibition (reduced carbohydrate absorption).

  6. Short-term effect of G-400, polyherbal formulation in the management of hyperglycemia and hyperlipidemia conditions in patients with type 2 diabetes mellitus

    PubMed ID: 24976431

    Multi‑herb formula including Salacia lowered fasting/postprandial glucose and HbA1c, but ingredient‑specific attribution is uncertain.

  7. Salacia Extract Improves Postprandial Glucose and Insulin Response: A Randomized Double-Blind, Placebo Controlled, Crossover Study in Healthy Volunteers

    PubMed ID: 27803937

    Sucrose‑load study showed dose‑dependent insulin lowering and tended to blunt glucose—supports inhibition of sugar absorption.

Digestive support (4)
  1. Salacia Extract Improves Postprandial Glucose and Insulin Response: A Randomized Double-Blind, Placebo Controlled, Crossover Study in Healthy Volunteers

    PubMed ID: 27803937

    Healthy volunteer sucrose‑load study showed blunted insulin/glucose responses consistent with reduced carbohydrate breakdown.

  2. Effects of a nutritional supplement containing Salacia oblonga extract and insulinogenic amino acids on postprandial glycemia, insulinemia, and breath hydrogen responses in healthy adults

    PubMed ID: 15975493

    Acute trial showed increased breath hydrogen (carbohydrate malabsorption) and reduced glucose rise—direct digestive enzyme (α‑glucosidase) effects.

  3. Effects of a medical food containing an herbal alpha-glucosidase inhibitor on postprandial glycemia and insulinemia in healthy adults

    PubMed ID: 15635348

    Dose–response increases in breath hydrogen and lowered insulin indicate altered carbohydrate digestion/absorption.

  4. Improvement in Human Immune Function with Changes in Intestinal Microbiota by Salacia reticulata Extract Ingestion: A Randomized Placebo-Controlled Trial

    PubMed ID: 26630568

    4‑week study increased Bifidobacterium substantially—clear gut‑microbiota effect relevant to digestion.

Detoxification (2)
  1. Nephroprotective role of salacia chinensis in diabetic CKD patients: a pilot study

    PubMed ID: 22945782

    Diabetic CKD pilot showed stabilization of creatinine/creatinine clearance vs placebo and reduced IL‑6/homocysteine—direct renal benefit signal.

  2. Effects of Salacia oblonga on cardiovascular risk factors in chronic kidney disease patients: a prospective study

    PubMed ID: 25579717

    6‑month randomized CKD study reported stabilization of renal function and favorable biochemical changes—strong evidence in CKD populations.

Inflammation (2)
  1. Effects of Salacia oblonga on cardiovascular risk factors in chronic kidney disease patients: a prospective study

    PubMed ID: 25579717

    6‑month CKD RCT showed significant CRP and IL‑6 reductions—strong evidence of anti‑inflammatory effect in that population.

  2. Nephroprotective role of salacia chinensis in diabetic CKD patients: a pilot study

    PubMed ID: 22945782

    Diabetic CKD pilot reported IL‑6 decline and reduced homocysteine—indicative of reduced inflammatory burden.

Blood circulation (1)
  1. Effects of Salacia oblonga on cardiovascular risk factors in chronic kidney disease patients: a prospective study

    PubMed ID: 25579717

    Improved triglycerides and reduced inflammation in CKD may favor vascular health (moderate/indirect).

Cholesterol (1)
  1. Effects of Salacia oblonga on cardiovascular risk factors in chronic kidney disease patients: a prospective study

    PubMed ID: 25579717

    CKD trial showed reductions in triglycerides (and some cholesterol changes in diabetic subgroup), supporting lipid benefits.

Heart health (1)
  1. Effects of Salacia oblonga on cardiovascular risk factors in chronic kidney disease patients: a prospective study

    PubMed ID: 25579717

    CKD trial reported reduced triglycerides and inflammatory markers; these changes can benefit cardiovascular risk (moderate evidence).

Energy & Fatigue (1)
  1. A double blind randomised placebo controlled cross over study of a herbal preparation containing Salacia reticulata in the treatment of type 2 diabetes

    PubMed ID: 15707755

    Improved overall glycemic control (lower HbA1c) may contribute to steadier energy, though energy was not measured directly.

Weight management (1)
  1. Complementary treatment of obesity and overweight with salacia reticulata and vitamin d

    PubMed ID: 25008011

    Open randomized trial (Salacia + vitamin D + exercise) produced greater short‑term weight/fat loss, but effect is confounded.

Immune support (1)
  1. Improvement in Human Immune Function with Changes in Intestinal Microbiota by Salacia reticulata Extract Ingestion: A Randomized Placebo-Controlled Trial

    PubMed ID: 26630568

    Randomized 4‑week trial showed increased T‑cell activity, rise in Bifidobacterium and reduced 'immunological age'—direct immune benefit.

Similar by evidence

Supplements the same benefits carry qualifying findings for — a fact about the evidence graph, not a recommendation to swap.

Products with Salacia Reticulata

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3 products whose verified label declares Salacia Reticulata — not every bottle that mentions it in a title.