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Policosanol

12 benefits mapped to clinical evidence across supplements.

Dose per serving from products

256 products in our catalogue print how much Policosanol a serving holds.

Most common: 5 mg to 10 mg, 64% of 256 products.

Dose per servingProducts
2.5 mg or less
3
2.5 mg to 5 mg
20
5 mg to 10 mg
165
10 mg to 25 mg
48
25 mg to 50 mg
12
over 50 mg
8

Dose per serving from research

63 study groups in 45 studies say how much Policosanol participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 5 mg to 10 mg, 52% of 63 study groups.

Daily doseStudy groups
2.5 mg or less
1
2.5 mg to 5 mg
6
5 mg to 10 mg
33
10 mg to 25 mg
19
25 mg to 50 mg
4

See every study group

Commonly used together

13 of 63 study groups took Policosanol with something else. Shown: what 3 or more different studies gave.

What was given together, not what works together.

Taken withStudy groups
Red Yeast Rice
9
Berberine
8
Coenzyme Q10
4
Folic Acid
4
Astaxanthin
3

Benefit Evidence

LDL/TC ↓ ~20%

HDL ↑ ~10-30%

4,358 people

Lipids: LDL↓ HDL↑

Platelets/BP: less clotting

3,675 people
Wellbeing
Moderate

Lipids/BP: -25%

+HDL, fewer events

Platelets: -48.7% HPR

2,122 people

Antiplatelet, -70%

Walking, lipids

1,117 people

SBP −7 to −14

DBP −14%

1,350 people

Lipids: LDL↓ HDL↑

Stroke recovery: mRS↓ 80-88%

Inflammation/platelets↓

823 people
Endurance
Moderate

Exercise + recovery

Walking +33–69%

424 people

Walking +55-69%

Stroke recovery mRS↓

424 people
Vitality
Moderate

Cardiovascular recovery +87.5%

Lipids/claudication better

534 people
Antioxidant
Moderate

Lipid oxidation +21%

HDL/LDL shifts

168 people

Exercise capacity +VO2max

Walking distance +55-59%

107 people

↓ BP, ↓ HbA1c

↑ HDL, +6.3%

72 people

Research sources

Cholesterol (32)
  1. Effects of policosanol in older patients with type II hypercholesterolemia and high coronary risk

    PubMed ID: 11253161

    179 older hypercholesterolemic patients: substantial LDL/TC reductions and large HDL increases.

  2. Nutraceutical pill containing berberine versus ezetimibe on plasma lipid pattern in hypercholesterolemic subjects and its additive effect in patients with familial hypercholesterolemia on stable cholesterol-lowering treatment

    PubMed ID: 22998978

    Large nutraceutical pill (berberine+RYY+policosanol) produced big LDL decreases, but policosanol likely not the main driver.

  3. Effect on LDL-cholesterol of a large dose of a dietary supplement with plant extracts in subjects with untreated moderate hypercholesterolaemia: a randomised, double-blind, placebo-controlled study

    PubMed ID: 23266743

    Multi-component plant supplement including policosanol lowered LDL vs placebo; policosanol's independent contribution unclear.

  4. [A randomized, double-blind, placebo-controlled study of the antilipemic efficacy and tolerability of food supplement policosanol in patients with moderate hypercholesterolemia]

    PubMed ID: 16583932

    Rice policosanol 10 mg lowered total cholesterol and raised Apo A‑I but did not change LDL—partial lipid impact.

  5. Effects of addition of policosanol to omega-3 fatty acid therapy on the lipid profile of patients with type II hypercholesterolaemia

    PubMed ID: 16050054

    Notable LDL/TC reductions and HDL increases were seen, but policosanol was given with omega-3 (confounding).

  6. A comparison of the effects of D-003 and policosanol (5 and 10 mg/day) in patients with type II hypercholesterolemia: a randomized, double-blinded study

    PubMed ID: 16444910

    Dose-related modest LDL reductions (>=15% in many subjects) and HDL increases reported, albeit less than comparator.

  7. Concomitant use of policosanol and beta-blockers in older patients

    PubMed ID: 15689053

    Three-year randomized elderly study showed large, durable LDL reductions and HDL increases—strong direct evidence for lipid benefits.

  8. Comparison of the efficacy and tolerability of policosanol with atorvastatin in elderly patients with type II hypercholesterolaemia

    PubMed ID: 12534315

    Elderly study showed ~23% LDL lowering and modest HDL rise.

  9. Effects of policosanol on older patients with hypertension and type II hypercholesterolaemia

    PubMed ID: 12099160

    Large trial (n=589) demonstrating substantial LDL/TC lowering and HDL rise.

  10. Efficacy and tolerability of policosanol in hypercholesterolemic postmenopausal women

    PubMed ID: 11708573

    Postmenopausal study (n=56) showing clear LDL/TC reductions and modest HDL increase.

  11. Effects of policosanol 20 versus 40 mg/day in the treatment of patients with type II hypercholesterolemia: a 6-month double-blind study

    PubMed ID: 11708574

    Dose-comparison RCT showing robust LDL reductions (~27–28%) and HDL increases.

  12. Effects of policosanol on postmenopausal women with type II hypercholesterolemia

    PubMed ID: 10923280

    Well-powered RCT in postmenopausal women showing large, dose-related LDL and HDL improvements.

  13. [Comparative effects of policosanol and two HMG-CoA reductase inhibitors on type II hypercholesterolemia]

    PubMed ID: 10436712

    RCT reporting ~24% LDL reduction and HDL increase comparable to some statins.

  14. A comparative study of policosanol Versus acipimox in patients with type II hypercholesterolemia

    PubMed ID: 10645516

    Smaller RCT reporting total cholesterol decrease and good tolerability versus acipimox.

  15. Effects of policosanol in patients with type II hypercholesterolemia and additional coronary risk factors

    PubMed ID: 10223782

    Large RCT (n=437) with clear, clinically meaningful LDL reductions and HDL increases.

  16. Comparative study of the efficacy and tolerability of policosanol and lovastatin in patients with hypercholesterolemia and noninsulin dependent diabetes mellitus

    PubMed ID: 10939029

    Diabetic RCT where policosanol reduced LDL/TC and raised HDL versus lovastatin.

  17. A two-year study on the efficacy and tolerability of policosanol in patients with type II hyperlipoproteinaemia

    PubMed ID: 8871266

    Two-year RCT showing sustained LDL/TC reductions and HDL increases.

  18. Comparison of the efficacy, safety and tolerability of original policosanol versus other mixtures of higher aliphatic primary alcohols in patients with type II hypercholesterolemia

    PubMed ID: 12503776

    110-patient RCT with clear dose-dependent LDL/TC reductions and HDL increases.

  19. A randomized, double-blind, placebo-controlled trial to evaluate efficacy and tolerability of an optimized botanical combination in the management of patients with primary hypercholesterolemia and mixed dyslipidemia

    PubMed ID: 21674629

    Botanical mix with policosanol lowered LDL and TC in RCT (small sample; multiple botanicals).

  20. A Randomized, Double-Blinded, Placebo-Controlled, Clinical Study of the Effects of a Nutraceutical Combination (LEVELIP DUO(®)) on LDL Cholesterol Levels and Lipid Pattern in Subjects with Sub-Optimal Blood Cholesterol Levels (NATCOL Study)

    PubMed ID: 33066334

    8‑week RCT of combined nutraceutical (includes policosanol) produced large LDL, TC and apoB reductions vs placebo.

  21. The short-term supplementation of monacolin K improves the lipid and metabolic patterns of hypertensive and hypercholesterolemic subjects at low cardiovascular risk

    PubMed ID: 29951651

    Short (1‑month) controlled trial of a monacolin‑rich nutraceutical containing policosanol produced marked LDL/TC reductions.

  22. A nutraceutical combination reduces left ventricular mass in subjects with metabolic syndrome and left ventricular hypertrophy: A multicenter, randomized, double-blind, placebo-controlled trial

    PubMed ID: 31371114

    Armolipid Plus reduced LDL and total cholesterol and also decreased left ventricular mass in metabolic syndrome patients.

  23. Comparison of Low-Dose Statin Versus Low-Dose Statin + Armolipid Plus in High-Intensity Statin-Intolerant Patients With a Previous Coronary Event and Percutaneous Coronary Intervention (ADHERENCE Trial)

    PubMed ID: 28781026

    Adding Armolipid Plus to low‑dose statin produced substantial incremental LDL lowering in high‑risk patients.

  24. Usefulness of Nutraceuticals (Armolipid Plus) Versus Ezetimibe and Combination in Statin-Intolerant Patients With Dyslipidemia With Coronary Heart Disease

    PubMed ID: 26611120

    In statin‑intolerant coronary patients, Armolipid Plus (contains policosanol) improved LDL target attainment vs ezetimibe (multi‑component).

  25. Multiple functions of policosanol in elderly patients with dyslipidemia

    PubMed ID: 32703038

    Elderly dyslipidemic cohort showed LDL decreases with policosanol in pragmatic settings (mixed designs).

  26. Efficacy of a nutraceutical combination on lipid metabolism in patients with metabolic syndrome: a multicenter, double blind, randomized, placebo controlled trial

    PubMed ID: 30885221

    Armolipid Plus improved LDL, total cholesterol and sdLDL properties over 24 weeks (multi‑ingredient).

  27. Short-Term Consumption of Cuban Policosanol Lowers Aortic and Peripheral Blood Pressure and Ameliorates Serum Lipid Parameters in Healthy Korean Participants: Randomized, Double-Blinded, and Placebo-Controlled Study

    PubMed ID: 30841655

    Dose‑response RCT in prehypertensive adults showed clinically meaningful LDL reductions with policosanol monotherapy.

  28. Efficacy and Safety of Policosanol Plus Fenofibrate Combination Therapy in Elderly Patients with Mixed Dyslipidemia: A Randomized, Controlled Clinical Study

    PubMed ID: 30286820

    Elderly dyslipidemic patients had LDL/non‑HDL/TC decreases with policosanol (alone and combined) in randomized setting.

  29. [Effects of policosanol combined with simvastatin on serum lipids and sex hormones in male patients with hyperlipidemia]

    PubMed ID: 24113041

    Policosanol added to simvastatin produced larger LDL and TC reductions vs simvastatin+placebo (RCT), though confounded by combination therapy.

  30. Nutraceutical approach to moderate cardiometabolic risk: results of a randomized, double-blind and crossover study with Armolipid Plus

    PubMed ID: 24528686

    Armolipid Plus (multi-ingredient including policosanol) lowered LDL comparably to low-dose pravastatin; role of policosanol uncertain.

  31. A combined natural supplement lowers LDL cholesterol in subjects with moderate untreated hypercholesterolemia: a randomized placebo-controlled trial

    PubMed ID: 23815518

    Combined supplement including policosanol reduced LDL and ApoB in untreated hypercholesterolemics; attribution uncertain.

  32. [Effects of policosanol on serum lipids and heme oxygenase-1 in patients with hyperlipidemia]

    PubMed ID: 23302671

    Policosanol 20 mg/day lowered total cholesterol in hyperlipidemic patients in an open randomized trial.

Heart health (20)
  1. A double-blind, placebo-controlled study of the effects of policosanol in patients with intermittent claudication

    PubMed ID: 10063942

    Clinically meaningful functional improvements in peripheral arterial disease support cardiovascular wellbeing.

  2. A nutraceutical combination reduces left ventricular mass in subjects with metabolic syndrome and left ventricular hypertrophy: A multicenter, randomized, double-blind, placebo-controlled trial

    PubMed ID: 31371114

    Reduction in left ventricular mass plus improved lipids in metabolic syndrome patients supports cardiac‑structure and risk benefits.

  3. Policosanol (sugarcane wax alcohols) 20 mg/day in Cuban Patients With Grade I Hypertension: A Randomized, Double-Blind, Multicenter Study

    PubMed ID: 41032504

    Multicenter RCT in hypertensives with robust BP and LDL improvements supports cardiovascular wellness.

  4. Efficacy and Safety of Policosanol (Sugarcane Wax Alcohols) 20 mg/Day in Cuban Prehypertensive Patients: A Randomized, Double-Blind, Multicentre Study

    PubMed ID: 40189869

    Large randomized monotherapy trial showed clinically meaningful BP and LDL reductions—strong overall cardiovascular benefit.

  5. Multiple functions of policosanol in elderly patients with dyslipidemia

    PubMed ID: 32703038

    Multiple favorable vascular and inflammatory marker changes in elderly dyslipidemic patients support CV wellness.

  6. Efficacy of a nutraceutical combination on lipid metabolism in patients with metabolic syndrome: a multicenter, double blind, randomized, placebo controlled trial

    PubMed ID: 30885221

    Armolipid Plus improved LDL and atherogenic LDL properties in metabolic syndrome, benefiting cardiovascular risk profile.

  7. Short-Term Consumption of Cuban Policosanol Lowers Aortic and Peripheral Blood Pressure and Ameliorates Serum Lipid Parameters in Healthy Korean Participants: Randomized, Double-Blinded, and Placebo-Controlled Study

    PubMed ID: 30841655

    Dose‑dependent BP and lipid improvements in prehypertensive adults are directly cardiovascular‑relevant.

  8. Efficacy and Safety of Policosanol Plus Fenofibrate Combination Therapy in Elderly Patients with Mixed Dyslipidemia: A Randomized, Controlled Clinical Study

    PubMed ID: 30286820

    Lipid improvements and reduced arterial stiffness in elderly are favorable for cardiovascular wellness.

  9. Safety and efficacy of policosanol in patients with high on-treatment platelet reactivity after drug-eluting stent implantation: two-year follow-up results

    PubMed ID: 27328023

    Reduction of platelet reactivity after stenting and fewer minor bleeds demonstrates clinically relevant cardiovascular protection.

  10. [Effects of policosanol combined with simvastatin on serum lipids and sex hormones in male patients with hyperlipidemia]

    PubMed ID: 24113041

    Add‑on to simvastatin produced larger LDL/TC drops which are favorable for cardiovascular health (combination confounded).

  11. [Effects of policosanol on serum lipids and heme oxygenase-1 in patients with hyperlipidemia]

    PubMed ID: 23302671

    Total-cholesterol reduction and HO-1 decrease could reflect cardiovascular wellness, albeit in an open-label trial.

  12. Effects of a nutraceutical combination (berberine, red yeast rice and policosanols) on lipid levels and endothelial function randomized, double-blind, placebo-controlled study

    PubMed ID: 19699071

    LDL reduction and modest FMD improvement with a multi-ingredient product suggest cardiovascular benefit but policosanol not isolated.

  13. A comparison of the effects of D-003 and policosanol (5 and 10 mg/day) in patients with type II hypercholesterolemia: a randomized, double-blinded study

    PubMed ID: 16444910

    Modest dose-related lipid improvements imply some heart-health relevance though effects were moderate.

  14. Concomitant use of policosanol and beta-blockers in older patients

    PubMed ID: 15689053

    Durable lipid improvements, HDL rise, BP lowering and good tolerability over 3 years indicate broad cardiovascular wellness benefits.

  15. Effects of policosanol on older patients with hypertension and type II hypercholesterolaemia

    PubMed ID: 12099160

    Large, long study showing lipid improvements, HDL rise, fewer vascular SAEs and BP lowering—broad cardiovascular benefit.

  16. Effects of policosanol in older patients with type II hypercholesterolemia and high coronary risk

    PubMed ID: 11253161

    Older hypercholesterolemic cohort showed major lipid benefits and improved cardiovascular capacity.

  17. Effects of policosanol on postmenopausal women with type II hypercholesterolemia

    PubMed ID: 10923280

    Postmenopausal RCT with meaningful LDL/HDL/TC changes and good safety, relevant to heart disease risk.

  18. Effects of policosanol in patients with type II hypercholesterolemia and additional coronary risk factors

    PubMed ID: 10223782

    Large RCT with robust LDL reduction, HDL rise and good tolerability—key for cardiovascular risk reduction.

  19. Long-term therapy with policosanol improves treadmill exercise-ECG testing performance of coronary heart disease patients

    PubMed ID: 9760006

    Clinical CHD outcomes: improved exercise responses and fewer ischemic events when used long-term (clinical cardiovascular signals).

  20. Comparative study of policosanol, aspirin and the combination therapy policosanol-aspirin on platelet aggregation in healthy volunteers

    PubMed ID: 9425618

    Strong antiplatelet effects (comparable/additive to aspirin) reduce thrombotic risk component of cardiovascular disease.

Wellbeing (8)
  1. Beneficial Effect of Cuban Policosanol on Blood Pressure and Serum Lipoproteins Accompanied with Lowered Glycated Hemoglobin and Enhanced High-Density Lipoprotein Functionalities in a Randomized, Placebo-Controlled, and Double-Blinded Trial with Healthy Japanese

    PubMed ID: 36982259

    12-week RCT with multiple favorable changes (BP/HDL/HbA1c) that could support general wellness.

  2. A two-year study on the efficacy and tolerability of policosanol in patients with type II hyperlipoproteinaemia

    PubMed ID: 8871266

    Two-year maintenance study demonstrating sustained lipid improvements and good tolerability over long term.

  3. Effects of policosanol in patients with type II hypercholesterolemia and additional coronary risk factors

    PubMed ID: 10223782

    Large RCT showing durable lipid benefits and safety supportive of long-term wellness maintenance.

  4. Effects of policosanol on older patients with hypertension and type II hypercholesterolaemia

    PubMed ID: 12099160

    Large trial with sustained lipid, BP and SAE reductions consistent with maintenance of cardiovascular wellness.

  5. Concomitant use of policosanol and beta-blockers in older patients

    PubMed ID: 15689053

    Long-term safety/tolerability plus sustained cardiometabolic improvements in elderly support general wellness maintenance.

  6. Safety and efficacy of policosanol in patients with high on-treatment platelet reactivity after drug-eluting stent implantation: two-year follow-up results

    PubMed ID: 27328023

    Reduced platelet reactivity with fewer minor bleeds in post‑stent patients is clinically valuable for ongoing cardiovascular maintenance.

  7. Efficacy and Safety of Policosanol (Sugarcane Wax Alcohols) 20 mg/Day in Cuban Prehypertensive Patients: A Randomized, Double-Blind, Multicentre Study

    PubMed ID: 40189869

    Large RCT showing BP and LDL improvements with good tolerability supports general wellness maintenance in prehypertensives.

  8. Policosanol (sugarcane wax alcohols) 20 mg/day in Cuban Patients With Grade I Hypertension: A Randomized, Double-Blind, Multicenter Study

    PubMed ID: 41032504

    Robust BP and LDL reductions with policosanol in hypertensive patients and good tolerability support maintenance of health.

Blood circulation (10)
  1. Safety and efficacy of policosanol in patients with high on-treatment platelet reactivity after drug-eluting stent implantation: two-year follow-up results

    PubMed ID: 27328023

    Demonstrated reduced platelet reactivity after stenting, directly supporting improved patency/flow and lower thrombotic risk.

  2. Effects of a nutraceutical combination (berberine, red yeast rice and policosanols) on lipid levels and endothelial function randomized, double-blind, placebo-controlled study

    PubMed ID: 19699071

    Endothelial function (FMD) improved with a multi-ingredient product including policosanol—suggesting better blood flow though not isolated.

  3. Effects of policosanol (10 mg/d) versus aspirin (100 mg/d) in patients with intermittent claudication: a 10-week, randomized, comparative study

    PubMed ID: 18388038

    Improved walking distance vs aspirin supports a circulation benefit in symptomatic PAD patients (small study).

  4. A long-term study of policosanol in the treatment of intermittent claudication

    PubMed ID: 11228084

    Two-year claudication trial reported improved walking distance and ankle/arm index, consistent with better circulation.

  5. A double-blind, placebo-controlled study of the effects of policosanol in patients with intermittent claudication

    PubMed ID: 10063942

    Marked increases in walking distance in claudication patients imply improved peripheral blood flow/tolerance.

  6. Comparative study of policosanol, aspirin and the combination therapy policosanol-aspirin on platelet aggregation in healthy volunteers

    PubMed ID: 9425618

    Large reductions in platelet aggregation (multiple agonists) support improved rheology and reduced microthrombotic risk.

  7. Multiple functions of policosanol in elderly patients with dyslipidemia

    PubMed ID: 32703038

    Large elderly cohort showed lower platelet aggregation and fewer circulating endothelial cells, consistent with better vascular health/flow.

  8. Effect of policosanol successive dose increases on platelet aggregation in healthy volunteers

    PubMed ID: 9076841

    Dose-dependent platelet aggregation inhibition in healthy volunteers supports improved blood flow potential.

  9. Short-Term Consumption of Cuban Policosanol Lowers Aortic and Peripheral Blood Pressure and Ameliorates Serum Lipid Parameters in Healthy Korean Participants: Randomized, Double-Blinded, and Placebo-Controlled Study

    PubMed ID: 30841655

    BP and HDL/LDL improvements in prehypertensives support healthier vascular dynamics.

  10. Efficacy and Safety of Policosanol Plus Fenofibrate Combination Therapy in Elderly Patients with Mixed Dyslipidemia: A Randomized, Controlled Clinical Study

    PubMed ID: 30286820

    Improvements in arterial stiffness (ba‑PWV) indicate better arterial compliance and likely improved flow.

Blood pressure (6)
  1. Concomitant use of policosanol and beta-blockers in older patients

    PubMed ID: 15689053

    Study reported BP lowering in elderly beta‑blocker users over long-term policosanol treatment.

  2. Policosanol (sugarcane wax alcohols) 20 mg/day in Cuban Patients With Grade I Hypertension: A Randomized, Double-Blind, Multicenter Study

    PubMed ID: 41032504

    Multicenter randomized trial in grade I hypertensives showed substantial SBP reductions (~−14 mmHg) with policosanol monotherapy.

  3. Short-Term Consumption of Cuban Policosanol Lowers Aortic and Peripheral Blood Pressure and Ameliorates Serum Lipid Parameters in Healthy Korean Participants: Randomized, Double-Blinded, and Placebo-Controlled Study

    PubMed ID: 30841655

    Randomized placebo study in prehypertensive adults showed dose‑dependent central/peripheral BP lowering with policosanol.

  4. Efficacy and Safety of Policosanol (Sugarcane Wax Alcohols) 20 mg/Day in Cuban Prehypertensive Patients: A Randomized, Double-Blind, Multicentre Study

    PubMed ID: 40189869

    Large randomized Cuban trial: policosanol 20 mg/day significantly lowered SBP/DBP vs placebo (monotherapy).

  5. Beneficial Effect of Cuban Policosanol on Blood Pressure and Serum Lipoproteins Accompanied with Lowered Glycated Hemoglobin and Enhanced High-Density Lipoprotein Functionalities in a Randomized, Placebo-Controlled, and Double-Blinded Trial with Healthy Japanese

    PubMed ID: 36982259

    12-week RCT in healthy adults showed a significant systolic BP reduction (~7.1%).

  6. Effects of policosanol on older patients with hypertension and type II hypercholesterolaemia

    PubMed ID: 12099160

    Large trial in older hypertensive hypercholesterolemic patients reported systolic BP decreases (trial-level effect).

Healthy aging (5)
  1. Multiple functions of policosanol in elderly patients with dyslipidemia

    PubMed ID: 32703038

    Large elderly cohort had improved vascular/inflammatory markers with policosanol or atorvastatin, relevant to healthy aging.

  2. Efficacy and Safety of Policosanol Plus Fenofibrate Combination Therapy in Elderly Patients with Mixed Dyslipidemia: A Randomized, Controlled Clinical Study

    PubMed ID: 30286820

    Elderly randomized trial showed lipid improvements and reduced arterial stiffness with policosanol.

  3. [Long-term effect of policosanol on the functional recovery of non-cardioembolic ischemic stroke patients: a one year study]

    PubMed ID: 28169410

    Improved post‑stroke functional outcomes support maintenance of function during aging (secondary implication).

  4. Concomitant use of policosanol and beta-blockers in older patients

    PubMed ID: 15689053

    Three-year elderly study showing durable lipid and BP improvements and good tolerability suggests relevance to healthy aging.

  5. Effects of policosanol in the functional recovery of non-cardioembolic ischemic stroke hypertensive patients

    PubMed ID: 30350844

    Marked functional recovery in hypertensive stroke patients implies benefits relevant to aging populations' function.

Endurance (6)
  1. A double-blind, placebo-controlled study of the effects of policosanol in patients with intermittent claudication

    PubMed ID: 10063942

    Large increases in initial and absolute claudication distances directly reflect improved endurance.

  2. A long-term study of policosanol in the treatment of intermittent claudication

    PubMed ID: 11228084

    Two-year claudication study showed sustained walking-distance improvements consistent with enhanced stamina.

  3. Long-term therapy with policosanol improves treadmill exercise-ECG testing performance of coronary heart disease patients

    PubMed ID: 9760006

    Improvements in VO2max and exercise tolerance in CHD patients indicate enhanced endurance.

  4. Effects of policosanol in the functional recovery of non-cardioembolic ischemic stroke hypertensive patients

    PubMed ID: 30350844

    Substantial functional recovery in hypertensive stroke subgroup implies improved activity endurance; direct endurance testing not reported.

  5. [Long-term effect of policosanol on the functional recovery of non-cardioembolic ischemic stroke patients: a one year study]

    PubMed ID: 28169410

    Improved mobility/function after stroke suggests better functional endurance in daily activities, though not exercise endurance per se.

  6. Effects of policosanol (10 mg/d) versus aspirin (100 mg/d) in patients with intermittent claudication: a 10-week, randomized, comparative study

    PubMed ID: 18388038

    Short-term improvement in walking distance vs aspirin suggests endurance benefit (limited by trial size/duration).

Exercise recovery (6)
  1. Effects of policosanol (10 mg/d) versus aspirin (100 mg/d) in patients with intermittent claudication: a 10-week, randomized, comparative study

    PubMed ID: 18388038

    Short-term randomized trial showed increased walking distance vs aspirin, supporting improved exercise recovery (small sample/duration).

  2. A long-term study of policosanol in the treatment of intermittent claudication

    PubMed ID: 11228084

    Two-year claudication study documented sustained improvements in walking distance and functional status.

  3. A double-blind, placebo-controlled study of the effects of policosanol in patients with intermittent claudication

    PubMed ID: 10063942

    Claudiation trial produced large increases in walking distance, implying improved post-exertion recovery/tolerance.

  4. Long-term therapy with policosanol improves treadmill exercise-ECG testing performance of coronary heart disease patients

    PubMed ID: 9760006

    Long-term CHD trial showed improved exercise-ECG responses and increased VO2max (functional recovery after exertion).

  5. Effects of policosanol in the functional recovery of non-cardioembolic ischemic stroke hypertensive patients

    PubMed ID: 30350844

    Subgroup stroke trial (hypertensive patients) showed marked functional recovery with policosanol+aspirin vs aspirin alone.

  6. [Long-term effect of policosanol on the functional recovery of non-cardioembolic ischemic stroke patients: a one year study]

    PubMed ID: 28169410

    Policosanol+aspirin after ischemic stroke produced large functional/mobility gains vs aspirin alone (direct recovery outcome).

Vitality (5)
  1. Long-term therapy with policosanol improves treadmill exercise-ECG testing performance of coronary heart disease patients

    PubMed ID: 9760006

    Improved functional capacity/VO2max in CHD patients suggests better overall physical vitality.

  2. A double-blind, placebo-controlled study of the effects of policosanol in patients with intermittent claudication

    PubMed ID: 10063942

    Marked improvements in walking distance and symptoms in claudication imply improved day-to-day vitality.

  3. Concomitant use of policosanol and beta-blockers in older patients

    PubMed ID: 15689053

    Long-term tolerability with sustained lipid and BP improvements in elderly may contribute to overall vitality in that population.

  4. [Long-term effect of policosanol on the functional recovery of non-cardioembolic ischemic stroke patients: a one year study]

    PubMed ID: 28169410

    Marked functional gains after stroke imply improved day‑to‑day vitality in treated patients.

  5. Effects of policosanol in the functional recovery of non-cardioembolic ischemic stroke hypertensive patients

    PubMed ID: 30350844

    Large functional recovery in hypertensive stroke subgroup supports improved overall vitality.

Antioxidant (3)
  1. Beneficial Effect of Cuban Policosanol on Blood Pressure and Serum Lipoproteins Accompanied with Lowered Glycated Hemoglobin and Enhanced High-Density Lipoprotein Functionalities in a Randomized, Placebo-Controlled, and Double-Blinded Trial with Healthy Japanese

    PubMed ID: 36982259

    Improved HDL functionality in Japanese adults suggests enhanced anti-oxidative HDL actions.

  2. Effects of policosanol and lovastatin on lipid profile and lipid peroxidation in patients with dyslipidemia associated with type 2 diabetes mellitus

    PubMed ID: 12837046

    Diabetic dyslipidemic trial showed increased LDL oxidation lag time (improved LDL resistance to oxidation).

  3. A randomized, double-blind, placebo-controlled trial to evaluate efficacy and tolerability of an optimized botanical combination in the management of patients with primary hypercholesterolemia and mixed dyslipidemia

    PubMed ID: 21674629

    Trial of botanical combination including policosanol showed reductions in oxidative stress markers (MDA/CRP reported).

Energy & Fatigue (2)
  1. Long-term therapy with policosanol improves treadmill exercise-ECG testing performance of coronary heart disease patients

    PubMed ID: 9760006

    VO2max and exercise performance gains indicate increased physiological energy/functional capacity.

  2. A double-blind, placebo-controlled study of the effects of policosanol in patients with intermittent claudication

    PubMed ID: 10063942

    Substantial increases in walking distance consistent with greater exercise-derived energy/endurance.

Metabolism (1)
  1. Beneficial Effect of Cuban Policosanol on Blood Pressure and Serum Lipoproteins Accompanied with Lowered Glycated Hemoglobin and Enhanced High-Density Lipoprotein Functionalities in a Randomized, Placebo-Controlled, and Double-Blinded Trial with Healthy Japanese

    PubMed ID: 36982259

    Reported modest HbA1c reduction and HDL improvements (metabolic parameter benefits).

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