Horse Chestnut
8 benefits mapped to clinical evidence across supplements.
Dose per serving from products
103 products in our catalogue print how much Horse Chestnut a serving holds.
Most common: 100 mg to 250 mg, 48% of 103 products.
| Dose per serving | Products |
|---|---|
| 50 mg or less | 6 |
| 50 mg to 100 mg | 6 |
| 100 mg to 250 mg | 49 |
| 250 mg to 500 mg | 27 |
| 500 mg to 1 g | 9 |
| 1 g to 2.5 g | 6 |
Benefit Evidence
Research sources
Blood circulation (4)
- Medical edema protection--clinical benefit in patients with chronic deep vein incompetence. A placebo controlled double blind study
PubMed ID: 1621440
RDBPC trial showed reduced leg volume and improved phlebodynamometry (replenishment time) indicating better venous flow.
- Aescin and troxerutin as a successful combination for the treatment of inner ear perfusion disturbances
PubMed ID: 18222671
Aescin-containing combo improved hearing in perfusion-related inner-ear disorders—suggests perfusion benefit (combination product).
- Comparative clinical efficacy and tolerability of oxerutins and horse chestnut extract in patients with chronic venous insufficiency
PubMed ID: 8737631
Moderate-sized trial showed leg-volume reductions versus comparator—supports improved circulation.
- Comparison of leg compression stocking and oral horse-chestnut seed extract therapy in patients with chronic venous insufficiency
PubMed ID: 8569363
Large RCT in CVI showed edema reduction equivalent to compression—strong indicator of improved venous circulation.
Joint mobility (3)
- Comparative clinical efficacy and tolerability of oxerutins and horse chestnut extract in patients with chronic venous insufficiency
PubMed ID: 8737631
Leg-volume reductions in postmenopausal CVI patients imply potential mobility benefit.
- Comparison of leg compression stocking and oral horse-chestnut seed extract therapy in patients with chronic venous insufficiency
PubMed ID: 8569363
Edema reduction in large RCT likely to facilitate mobility via less swelling and discomfort.
- Medical edema protection--clinical benefit in patients with chronic deep vein incompetence. A placebo controlled double blind study
PubMed ID: 1621440
Reduced leg volume and improved phlebodynamometry could translate to better mobility in CVI patients.
Swelling relief (3)
- Comparative clinical efficacy and tolerability of oxerutins and horse chestnut extract in patients with chronic venous insufficiency
PubMed ID: 8737631
AUC-based leg-volume reductions observed with HCE in postmenopausal CVI patients.
- Comparison of leg compression stocking and oral horse-chestnut seed extract therapy in patients with chronic venous insufficiency
PubMed ID: 8569363
Large, well-powered RCT showed clinically meaningful decrease in leg volume vs placebo.
- Medical edema protection--clinical benefit in patients with chronic deep vein incompetence. A placebo controlled double blind study
PubMed ID: 1621440
RDBPC trial showed statistically significant reductions in leg volume and circumference measures.
Vascular health (3)
- Comparison of leg compression stocking and oral horse-chestnut seed extract therapy in patients with chronic venous insufficiency
PubMed ID: 8569363
Robust RCT evidence of edema reduction comparable to compression supports broad vascular support in CVI.
- Medical edema protection--clinical benefit in patients with chronic deep vein incompetence. A placebo controlled double blind study
PubMed ID: 1621440
Randomized trial showing improved leg-volume and phlebodynamometry indicates systemic venous benefit.
- Comparative clinical efficacy and tolerability of oxerutins and horse chestnut extract in patients with chronic venous insufficiency
PubMed ID: 8737631
Clinical leg-volume improvements add moderate support for vascular benefits overall.
Pain relief (1)
- Comparison of leg compression stocking and oral horse-chestnut seed extract therapy in patients with chronic venous insufficiency
PubMed ID: 8569363
Symptom improvements reported in CVI RCTs suggest reduction in pain/discomfort.
Inflammation (1)
- Clinical efficacy of horsechestnut seed extract in the treatment of venous ulceration
PubMed ID: 16620045
Venous ulcer RCT: no healing benefit but reduced wound slough (marker of local inflammation) and fewer dressing changes.
Skin appearance (1)
- Clinical efficacy of horsechestnut seed extract in the treatment of venous ulceration
PubMed ID: 16620045
Venous ulcer trial: significant reduction in wound slough and fewer dressing changes → cleaner/healthier wound appearance.
Exercise recovery (1)
- Medical edema protection--clinical benefit in patients with chronic deep vein incompetence. A placebo controlled double blind study
PubMed ID: 1621440
Phlebodynamometry showed improved replenishment time/pressure—directly relevant to recovery after standing.
Similar by evidence
Supplements the same benefits carry qualifying findings for — a fact about the evidence graph, not a recommendation to swap.
Products with Horse Chestnut
Search all155 products whose verified label declares Horse Chestnut — not every bottle that mentions it in a title.