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Gamboge

10 benefits mapped to clinical evidence across supplements.

Benefit Evidence

Weight -5kg, waist -10cm

Fat loss, weight loss

519 people
Metabolism
Moderate

Lipid lowering: TC/LDL/TG

Insulin/glucose improved; weight ↓

296 people

Lower IL-6, IL-1β

GCF antioxidants +TAOC

208 people

Gingival inflammation biomarkers ↓

Urinary symptoms/flow improved

208 people

Antioxidants +18%

Inflammation markers down

99 people

Mood/anxiety/function +4.2

Post-stop worsening

152 people

Mood +4.2, anxiety

Functioning +4.5

152 people

Smoothness/texture +1.0

Acne/inflammation ↓

60 people

Hunger↓ Satiety↑

Snack intake↓

57 people

Glycogen +100%, insulin ↓

Strength/lean mass ↑

38 people

Research sources

Weight management (7)
  1. Efficacy of Slim339 in reducing body weight of overweight and obese human subjects

    PubMed ID: 17639559

    60‑day double‑blind trial of a multi‑extract product containing Garcinia showed meaningful average weight loss vs placebo (multi‑ingredient).

  2. Reduction of adipose tissue and body weight: effect of water soluble calcium hydroxycitrate in Garcinia atroviridis on the short term treatment of obese women in Thailand

    PubMed ID: 17215177

    In obese women on a 1000 kcal/day diet, calcium HCA produced modestly greater short‑term weight and fat loss vs placebo.

  3. Efficacy of 12 weeks supplementation of a botanical extract-based weight loss formula on body weight, body composition and blood chemistry in healthy, overweight subjects--a randomised double-blind placebo-controlled clinical trial

    PubMed ID: 17052970

    Botanical extract formula including Garcinia reduced body fat percentage though not total weight—support for body composition changes.

  4. Efficacy and tolerability of an herbal formulation for weight management

    PubMed ID: 23767862

    Pooled/published data for a mangosteen‑containing herbal blend showed substantial, significant weight and waist losses (blend product).

  5. Efficacy and tolerability of a novel herbal formulation for weight management

    PubMed ID: 23784895

    8‑week RCT of a mangosteen‑containing blend found clinically significant weight loss and improved adiponectin (blend product).

  6. IQP-GC-101 reduces body weight and body fat mass: a randomized, double-blind, placebo-controlled study

    PubMed ID: 24797657

    IQP‑GC‑101 (contains Garcinia cambogia) plus diet produced modest but significant extra weight and fat loss versus placebo.

  7. Efficacy and tolerability of Meratrim for weight management: a randomized, double-blind, placebo-controlled study in healthy overweight human subjects

    PubMed ID: 27558585

    Meratrim (contains mangosteen rind) produced ~5 kg weight loss and marked waist reduction vs placebo over 16 weeks—strong trial of a blend.

Metabolism (5)
  1. Efficacy and tolerability of Meratrim for weight management: a randomized, double-blind, placebo-controlled study in healthy overweight human subjects

    PubMed ID: 27558585

    Meratrim (includes mangosteen) produced weight loss and large triglyceride reductions—clinically meaningful metabolic effects (blend product).

  2. The effect of hydroxy citric acid supplementation with calorie-restricted diet on metabolic, atherogenic and inflammatory biomarkers in women with non-alcoholic fatty liver disease: a randomized controlled clinical trial

    PubMed ID: 35416190

    HCA + calorie restriction in NAFLD showed modest changes in metabolic markers, but effects were limited and mixed.

  3. Evaluation of the pharmacotherapeutic efficacy of Garcinia cambogia plus Amorphophallus konjac for the treatment of obesity

    PubMed ID: 18729243

    Garcinia+konjac produced substantial reductions in total and LDL cholesterol versus placebo—strong metabolic lipid effect (multi‑ingredient).

  4. Hypolipemic effect of Garcinia cambogia in obese women

    PubMed ID: 24133059

    Garcinia treatment significantly lowered triglycerides in obese women—clear metabolic lipid benefit (no weight change).

  5. Efficacy and tolerability of an herbal formulation for weight management

    PubMed ID: 23767862

    Herbal blend containing mangosteen improved weight/BMI and adiponectin—metabolic biomarker changes (multi‑ingredient).

Detoxification (2)
  1. The Clinical Effect of a Propolis and Mangosteen Extract Complex in Subjects with Gingivitis: A Randomized, Double-Blind, and Placebo-Controlled Clinical Trial

    PubMed ID: 39275315

    Oral propolis–mangosteen complex produced large reductions in crevicular inflammatory biomarkers indicating a strong local 'cleansing' anti‑inflammatory effect.

  2. Clinical and Immunological Efficacy of Mangosteen and Propolis Extracted Complex in Patients with Gingivitis: A Multi-Centered Randomized Controlled Clinical Trial

    PubMed ID: 34444764

    Oral mangosteen+propolis reduced gingival indices and crevicular IL‑6, supporting a gentle oral anti‑inflammatory/cleansing action.

Wellbeing (2)
  1. Evaluation of the Therapeutic Potential of Garcinia cambogia Alone or in Combination With Silodosin in the Management of LUTS/BPH: A Prospective Randomized Controlled Study

    PubMed ID: 40209997

    Garcinia extract improved LUTS/BPH measures (symptoms, PSA/prostate measures), suggesting a restorative effect on urologic physiological balance in men studied.

  2. The Clinical Effect of a Propolis and Mangosteen Extract Complex in Subjects with Gingivitis: A Randomized, Double-Blind, and Placebo-Controlled Clinical Trial

    PubMed ID: 39275315

    Multicenter RCT (propolis–mangosteen) produced large, significant reductions in gingival inflammatory biomarkers — supports rebalancing local inflammation.

Vitality (2)
  1. Effect of a mangosteen dietary supplement on human immune function: a randomized, double-blind, placebo-controlled trial

    PubMed ID: 19697997

    30‑day mangosteen product increased some T‑cell measures and lowered CRP in healthy middle‑aged adults—supports systemic vitality markers (complex product).

  2. Evaluation of Mangosteen juice blend on biomarkers of inflammation in obese subjects: a pilot, dose finding study

    PubMed ID: 19843321

    Mangosteen juice blend produced dose‑dependent CRP reductions and modest BMI/body‑fat changes—pilot evidence of systemic benefit.

Daily comfort (1)
  1. The efficacy of adjunctive Garcinia mangostana Linn. (mangosteen) pericarp extract for bipolar depression: 24-week randomised controlled trial

    PubMed ID: 40637133

    Improvements in depression/anxiety/functioning in bipolar depression imply a meaningful benefit to daily wellbeing for that clinical group.

Mood balance (1)
  1. The efficacy of adjunctive Garcinia mangostana Linn. (mangosteen) pericarp extract for bipolar depression: 24-week randomised controlled trial

    PubMed ID: 40637133

    24‑week RCT in bipolar depression showed modest but statistically significant improvements in depression and anxiety scores versus placebo.

Skin appearance (1)
  1. Clinical efficacy of herbal extracts in treatment of mild to moderate acne vulgaris: an 8-week, double-blinded, randomized, controlled trial

    PubMed ID: 31424962

    8‑week RCT with topical/oral herbal mix including mangosteen reduced acne lesion counts and local inflammatory markers — direct skin improvement evidence.

Appetite suppression (1)
  1. Short-term effects of a green coffee extract-, Garcinia c ambogia- and L-carnitine-containing chewing gum on snack intake and appetite regulation

    PubMed ID: 27885554

    Chewing gum with Garcinia, green coffee and L‑carnitine reduced snack intake and hunger in a short crossover trial (multi‑ingredient/gum format).

Energy & Fatigue (1)
  1. Combined extracts of Garcinia mangostana fruit rind and Cinnamomum tamala leaf supplementation enhances muscle strength and endurance in resistance trained males

    PubMed ID: 30348185

    Mangosteen-containing blend improved strength/endurance in resistance-trained men (likely energy/endurance effect; multi-herb formula).

Similar by evidence

Supplements the same benefits carry qualifying findings for — a fact about the evidence graph, not a recommendation to swap.

Products with Gamboge

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1 product whose verified label declares Gamboge — not every bottle that mentions it in a title.