Clove
8 benefits mapped to clinical evidence across supplements.
Dose per serving from products
130 products in our catalogue print how much Clove a serving holds.
Most common: 25 mg to 50 mg, 45% of 130 products.
| Dose per serving | Products |
|---|---|
| 5 mg or less | 6 |
| 5 mg to 10 mg | 3 |
| 10 mg to 25 mg | 8 |
| 25 mg to 50 mg | 59 |
| 50 mg to 100 mg | 28 |
| 100 mg to 250 mg | 11 |
| 250 mg to 500 mg | 11 |
| over 500 mg | 4 |
Benefit Evidence
Oral heat pain +desensitization
Needle pain -1.7 VAS
Anal fissure healing +48%
Research sources
Oral health (8)
- A randomized clinical study to examine the oral hygiene efficacy of a novel herbal toothpaste with zinc over a 6-month period
PubMed ID: 33866666
6âmonth RCT of an herbal/zinc toothpaste containing clove showed substantial reductions in plaque, gingival index and bleeding versus fluoride control.
- A randomised double-blind placebo-controlled study on the effects of a herbal toothpaste on gingival bleeding, oral hygiene and microbial variables
PubMed ID: 21542426
12âweek doubleâblind RCT: multiâherb dentifrice containing clove improved plaque, bleeding and salivary anaerobic bacteria versus placebo.
- Effect of clove mouthwash on the incidence of ventilator-associated pneumonia in intensive care unit patients: a comparative randomized triple-blind clinical trial
PubMed ID: 36961592
Clove mouthwash substantially lowered VAP incidence and oral secretions in ventilated patients, indicating clinically meaningful oral antimicrobial/health effects.
- The effect of clove and benzocaine versus placebo as topical anesthetics
PubMed ID: 16530911
Topical clove gel produced significant oral mucosal anesthesia comparable to benzocaine in a randomized human study â directly relevant to dental/oral discomfort.
- Clinical efficacy of a herbal dentifrice on dentinal hypersensitivity: a randomized controlled clinical trial
PubMed ID: 24320906
12âweek randomized trial: herbal dentifrice (likely containing clove) significantly reduced dentinal hypersensitivity to air and cold vs placebo.
- Eugenol and carvacrol induce temporally desensitizing patterns of oral irritation and enhance innocuous warmth and noxious heat sensation on the tongue
PubMed ID: 23791894
Eugenol (from clove) produced rapid oral desensitization and altered pain perception in controlled human testsâmechanistic support for tooth/desensitizing effects.
- The effects of an Ayurvedic medicinal toothpaste on clinical, microbiological and oral hygiene parameters in patients with chronic gingivitis: a double-blind, randomised, placebo-controlled, parallel allocation clinical trial
PubMed ID: 26778391
6âmonth RCT in chronic gingivitis showed an Ayurvedic herbal toothpaste (includes clove) produced sustained, significant reductions in plaque, bleeding and pocket depth.
- The effects of a novel herbal toothpaste on salivary lactate dehydrogenase as a measure of cellular integrity
PubMed ID: 33064207
12âweek clinical trial of a herbal toothpaste (with clove) reduced plaque, gingival index and salivary LDH versus controlârobust oralâhealth signal for the product.
Pain relief (4)
- The effect of clove and benzocaine versus placebo as topical anesthetics
PubMed ID: 16530911
Human randomized subjectâblinded study: topical clove gel reduced needleâstick oral mucosa pain similar to 20% benzocaine â good evidence for local analgesic effect.
- Eugenol and carvacrol induce temporally desensitizing patterns of oral irritation and enhance innocuous warmth and noxious heat sensation on the tongue
PubMed ID: 23791894
Human psychophysics with eugenol (major clove constituent) showed rapid desensitization of oral irritation and altered pain perception, supporting topical analgesic potential.
- The effects of eugenol nanoemulsion on pain caused by arteriovenous fistula cannulation in hemodialysis patients: A randomized double-blinded controlled cross-over trial
PubMed ID: 32951708
Doubleâblind RCT: topical 4% eugenol nanoemulsion markedly reduced cannulation pain in hemodialysis patients â strong clinical analgesic signal for a clove constituent.
- Clove oil cream: a new effective treatment for chronic anal fissure
PubMed ID: 17573751
Topical clove oil cream improved chronic anal fissure healing and lowered anal pressures, with symptomatic/pain benefit reported in RCT.
Antimicrobial (2)
- Effect of clove mouthwash on the incidence of ventilator-associated pneumonia in intensive care unit patients: a comparative randomized triple-blind clinical trial
PubMed ID: 36961592
Randomized RCT: clove mouthwash halved ventilatorâassociated pneumonia vs chlorhexidine â strong clinical antimicrobial/antiâinfection effect in ICU setting.
- Investigation of the effectiveness of Syzygium aromaticum, Lavandula angustifolia and Geranium robertianum essential oils in the treatment of acute external otitis: a comparative trial with ciprofloxacin
PubMed ID: 23274083
Essentialâoil ear drop containing clove performed comparably to ciprofloxacin for external ear infection; clove was part of a multiâoil mix so its specific contribution is uncertain.
Respiratory comfort (1)
- Effect of clove mouthwash on the incidence of ventilator-associated pneumonia in intensive care unit patients: a comparative randomized triple-blind clinical trial
PubMed ID: 36961592
Clove mouthwash reduced ventilatorâassociated pneumonia incidence and secretions, a respiratory infection endpoint implying benefit for respiratory tract microbial burden/secretions.
Digestive support (1)
- [Inhibitory Effects of β-caryophyllene on Helicobacter pylori Infection: A Randomized Double-blind, Placebo-controlled Study]
PubMed ID: 31650795
RCT of βâcaryophyllene (a clove constituent) in H. pylori patients improved dyspepsia symptoms and lowered ILâ1β, directly supporting symptomatic digestive benefit.
Immune support (1)
- [Inhibitory Effects of β-caryophyllene on Helicobacter pylori Infection: A Randomized Double-blind, Placebo-controlled Study]
PubMed ID: 31650795
βâcaryophyllene RCT decreased serum ILâ1β, indicating an antiâinflammatory/immuneâmodulating effect of a clove constituent.
Skin repair (1)
- Clove oil cream: a new effective treatment for chronic anal fissure
PubMed ID: 17573751
Randomized trial: topical 1% clove oil cream markedly improved healing rates and reduced anorectal pressures in chronic anal fissure â strong woundâhealing evidence for topical clove oil.
Focus & concentration (1)
- Aromatherapy blend of thyme, orange, clove bud, and frankincense boosts energy levels in post-COVID-19 female patients: A randomized, double-blinded, placebo controlled clinical trial
PubMed ID: 35341944
Randomized doubleâblind trial: inhalation of an essentialâoil blend that included clove reduced fatigue and depressive symptoms vs placeboâstrong effect for the blend.
Similar by evidence
Supplements the same benefits carry qualifying findings for â a fact about the evidence graph, not a recommendation to swap.
Products with Clove
Search all379 products whose verified label declares Clove â not every bottle that mentions it in a title.
Being studied right now
Recruiting clinical trials registered on ClinicalTrials.gov. A trial in progress has no result yet â this is what the field is asking, not what it found.