Cissus Quadrangularis
4 benefits mapped to clinical evidence across supplements.
Dose per serving from products
23 products in our catalogue print how much Cissus Quadrangularis a serving holds.
Most common: 25 mg to 50 mg, 61% of 23 products.
| Dose per serving | Products |
|---|---|
| 25 mg to 50 mg | 14 |
| 50 mg to 100 mg | 2 |
| 100 mg to 250 mg | 0 |
| 250 mg to 500 mg | 5 |
| 500 mg to 1 g | 2 |
Dose per serving from research
7 study groups in 6 studies say how much Cissus Quadrangularis participants took a day.
These are the doses the studies gave. They are not a recommendation.
Most common: 250 mg to 500 mg, 43% of 7 study groups.
| Daily dose | Study groups |
|---|---|
| 250 mg or less | 1 |
| 250 mg to 500 mg | 3 |
| 500 mg to 1 g | 1 |
| 1 g to 2.5 g | 2 |
Benefit Evidence
Research sources
Metabolism (2)
- The Use of a Stem and Leaf Aqueous Extract of Cissus quadrangularis (CQR-300) to Reduce Body Fat and Other Components of Metabolic Syndrome in Overweight Participants
PubMed ID: 29912570
Single‑ingredient RCT showed marked reductions in fasting glucose and body fat—strong metabolic evidence.
- Effects of Dichrostachys glomerata and Cissus quadrangularis Extracts on GLP-1 Secretion and DPP-4 Activity in Overweight and Obese Individuals: A Randomized Controlled Trial
PubMed ID: 41597327
Incretin increases and DPP‑4 inhibition with weight loss indicate clear metabolic effects.
Weight management (2)
- The Use of a Stem and Leaf Aqueous Extract of Cissus quadrangularis (CQR-300) to Reduce Body Fat and Other Components of Metabolic Syndrome in Overweight Participants
PubMed ID: 29912570
Randomized, double‑blind single‑ingredient CQR‑300 trial with ~7.4 kg loss and large fat/glucose improvements—strong direct evidence.
- Effects of Dichrostachys glomerata and Cissus quadrangularis Extracts on GLP-1 Secretion and DPP-4 Activity in Overweight and Obese Individuals: A Randomized Controlled Trial
PubMed ID: 41597327
Large 16‑week RCT with standardized CQ extract showing ~4.7 kg loss plus GLP‑1 and DPP‑4 effects—robust evidence.
Wellbeing (2)
- The Use of a Stem and Leaf Aqueous Extract of Cissus quadrangularis (CQR-300) to Reduce Body Fat and Other Components of Metabolic Syndrome in Overweight Participants
PubMed ID: 29912570
Single‑ingredient trial with broad metabolic and body composition benefits supportive of general wellness.
- Effects of Dichrostachys glomerata and Cissus quadrangularis Extracts on GLP-1 Secretion and DPP-4 Activity in Overweight and Obese Individuals: A Randomized Controlled Trial
PubMed ID: 41597327
Robust RCT showing metabolic improvements (incretin, weight) that plausibly contribute to overall health.
Appetite suppression (1)
- Effects of Dichrostachys glomerata and Cissus quadrangularis Extracts on GLP-1 Secretion and DPP-4 Activity in Overweight and Obese Individuals: A Randomized Controlled Trial
PubMed ID: 41597327
Raised postprandial GLP‑1 and lowered DPP‑4 activity—mechanistically consistent with reduced appetite and observed weight loss.
Similar by evidence
Supplements the same benefits carry qualifying findings for — a fact about the evidence graph, not a recommendation to swap.
Products with Cissus Quadrangularis
Search all45 products whose verified label declares Cissus Quadrangularis — not every bottle that mentions it in a title.
Being studied right now
Recruiting clinical trials registered on ClinicalTrials.gov. A trial in progress has no result yet — this is what the field is asking, not what it found.