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Cissus Quadrangularis: study protocols

7 study groups say how much Cissus Quadrangularis participants took a day. These are the doses the studies gave. They are not a recommendation.

Cissus Quadrangularis: what the research found →

Dose per serving from products

23 products in our catalogue print how much Cissus Quadrangularis a serving holds.

Most common: 25 mg to 50 mg, 61% of 23 products.

Dose per servingProducts
25 mg to 50 mg
14
50 mg to 100 mg
2
100 mg to 250 mg
0
250 mg to 500 mg
5
500 mg to 1 g
2

Dose per serving from research

7 study groups in 6 studies say how much Cissus Quadrangularis participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 250 mg to 500 mg, 43% of 7 study groups.

Daily doseStudy groups
250 mg or less
1
250 mg to 500 mg
3
500 mg to 1 g
1
1 g to 2.5 g
2

Commonly used together

None of these 7 study groups took Cissus Quadrangularis with anything else.

7 study groups

Study
The Use of a Stem and Leaf Aqueous Extract of Cissus quadrangularis (CQR-300) to Reduce Body Fat and Other Components of Metabolic Syndrome in Overweight Participants
2019 · CQR-300 · Adults aged 25–60 years with overweight (BMI 25–29.9), excluding people with diabetes and pregnant or lactating women
300 mg8 weeks30
The use of a Cissus quadrangularis/Irvingia gabonensis combination in the management of weight loss: a double-blind placebo-controlled study
2008 · CQ-only extract · Overweight or obese adults aged 21–44 years, men and women; people with diabetes and pregnant or lactating women were excluded.
300 mg10 weeks24
Cissus Quadrangularis enhances UCP1 mRNA, indicative of white adipocyte browning and decreases central obesity in humans in a randomized trial
2021 · CQ extract-treated group · Thai adults over 18 years with obesity (BMI ≥25 kg/m²); men and women
600 mg8 weeks15
Evaluation of osteogenic potential of Cissus quadrangularis on mandibular alveolar ridge distraction
2021 · Group II · Adults with atrophic posterior mandible requiring implant placement; mean age 56.7 years, 60% male and 40% female
250 mg6 weeks10
The effect of Cissus quadrangularis L. on delaying bone loss in postmenopausal women with osteopenia: A randomized placebo-controlled trial
2022 · CQ1.2 · Postmenopausal women older than 40 years with osteopenia, 1–10 years since their last period
1.2 g24 weeks—
The effect of Cissus quadrangularis L. on delaying bone loss in postmenopausal women with osteopenia: A randomized placebo-controlled trial
2022 · CQ1.6 · Postmenopausal women older than 40 years with osteopenia, 1–10 years since their last period
1.6 g24 weeks—
Effects of Dichrostachys glomerata and Cissus quadrangularis Extracts on GLP-1 Secretion and DPP-4 Activity in Overweight and Obese Individuals: A Randomized Controlled Trial
2025 · CQE 300 mg/day · Overweight or obese adults aged 25–59 years, with BMI 25–34.9 kg/m²
300 mg16 weeks62