Peppermint Oil
10 benefits mapped to clinical evidence across supplements.
Dose per serving from products
61 products in our catalogue print how much Peppermint Oil a serving holds.
Most common: 25 mg to 50 mg, 30% of 61 products.
| Dose per serving | Products |
|---|---|
| 1 mg to 2.5 mg | 5 |
| 2.5 mg to 5 mg | 6 |
| 5 mg to 10 mg | 4 |
| 10 mg to 25 mg | 3 |
| 25 mg to 50 mg | 18 |
| 50 mg to 100 mg | 7 |
| 100 mg to 250 mg | 10 |
| 250 mg to 500 mg | 7 |
| over 500 mg | 1 |
Dose per serving from research
10 study groups in 6 studies say how much Peppermint Oil participants took a day.
These are the doses the studies gave. They are not a recommendation.
Most common: 100 mg to 250 mg, 50% of 10 study groups.
| Daily dose | Study groups |
|---|---|
| 100 mg to 250 mg | 5 |
| 250 mg to 500 mg | 0 |
| 500 mg to 1 g | 4 |
| 1 g to 2.5 g | 1 |
Commonly used together
4 of 10 study groups took Peppermint Oil with something else. Shown: what 3 or more different studies gave.
What was given together, not what works together.
| Taken with | Study groups |
|---|---|
| caraway oil | 4 |
Benefit Evidence
Research sources
Stomach comfort (18)
- Multicenter phase II randomized study evaluating dose-response of antiperistaltic effect of L-menthol sprayed onto the gastric mucosa for upper gastrointestinal endoscopy
PubMed ID: 22348831
Lâmenthol spray doseâdependently suppressed gastric peristalsis, indicating direct gastric relaxant effects.
- Efficacy of Peppermint oil in diarrhea predominant IBS - a double blind randomized placebo - controlled study
PubMed ID: 23416804
IBS (diarrheaâpredominant) trial showed reduced abdominal pain at 6 weeksâconsistent with calmer stomach symptoms.
- Outcomes of Aromatherapy in Nausea and Vomiting After Total Knee Arthroplasty
PubMed ID: 39066774
Large trial after knee arthroplasty found peppermint aromatherapy reduced antiemetic medication use despite similar nausea scores.
- Does peppermint oil relieve spasm during barium enema?
PubMed ID: 7551780
Peppermint reduced colonic spasm during barium enema, demonstrating smooth muscle relaxing GI action.
- Efficacy of a fixed peppermint oil/caraway oil combination in non-ulcer dyspepsia
PubMed ID: 9006790
Entericâcoated peppermint/caraway markedly improved pain and global dyspeptic symptoms, consistent with calming stomach discomfort.
- Enteric-coated peppermint-oil capsules in the treatment of irritable bowel syndrome: a prospective, randomized trial
PubMed ID: 9430014
Colpermin significantly reduced abdominal pain and distension in IBS patients, directly supporting a calmer/stomach symptom profile.
- Treatment of functional dyspepsia with a fixed peppermint oil and caraway oil combination preparation as compared to cisapride. A multicenter, reference-controlled double-blind equivalence study
PubMed ID: 10604046
Peppermint+caraway was equivalent to cisapride for dyspepsiaâstrong evidence of calming gastric symptoms.
- [Peppermint oil-caraway oil fixed combination in non-ulcer dyspepsia--comparison of the effects of enteric preparations]
PubMed ID: 10192108
Multicenter trial of enteric peppermint/caraway reduced dyspeptic pain intensity and frequency.
- Efficacy and tolerability of a fixed combination of peppermint oil and caraway oil in patients suffering from functional dyspepsia
PubMed ID: 11121917
Significant reductions in pain, pressure/heaviness and strong global improvement in functional dyspepsia.
- Enteric-coated, pH-dependent peppermint oil capsules for the treatment of irritable bowel syndrome in children
PubMed ID: 11148527
Children with IBS had high responder rate (75% reduced pain) indicating calmer abdominal symptoms.
- Peppermint oil reduces gastric spasm during upper endoscopy: a randomized, double-blind, double-dummy controlled trial
PubMed ID: 12665756
Peppermint relaxed stomach contractions faster/better than hyoscineâdirect calming effect.
- Randomized trial: Peppermint oil (menthol) pharmacokinetics in children and effects on gut motility in children with functional abdominal pain: 540âmg vs. 900âmg dose comparison
PubMed ID: 40390282
Higherâdose peppermint in children reduced colonic and wholeâgut contraction frequencyâclear physiological calming of gut activity.
- Peppermint oil (Mintoil) in the treatment of irritable bowel syndrome: a prospective double blind placebo-controlled randomized trial
PubMed ID: 17420159
IBS trial with 75% responder rate (>50% reduction)âclear calming of abdominal symptoms.
- The effect of enteric-coated, delayed-release peppermint oil on irritable bowel syndrome
PubMed ID: 19507027
Delayedârelease peppermint reduced abdominal pain and improved QoLâsupports calmer stomach.
- A Novel Delivery System of Peppermint Oil Is an Effective Therapy for Irritable Bowel Syndrome Symptoms
PubMed ID: 26319955
Targeted release formulation provided rapid and sustained symptom relief in IBS, including abdominal pain and urgency.
- Examining the Effect of Peppermint Oil on Postoperative Nausea After Cervical Surgery
PubMed ID: 39447066
Randomized study after cervical spine surgery showed large, significant reductions in postoperative nausea, vomiting and antiemetic use with peppermint aromatherapy.
- The combination of L-menthol and caraway oil does not affect gastric function but increases hunger in healthy subjects
PubMed ID: 39056471
Peppermint+caraway reduced certain dyspeptic symptoms though core gastric function measures were unchanged.
- Randomised trial: Peppermint oil (menthol) pharmacokinetics in children and effects on gut motility in children with functional abdominal pain
PubMed ID: 34528282
Delayedârelease peppermint reduced average abdominal pain in children and altered gut contractility (exploratory evidence).
Bloating & gas (15)
- Peppermint oil reduces gastric spasm during upper endoscopy: a randomized, double-blind, double-dummy controlled trial
PubMed ID: 12665756
Topical/solution peppermint relaxed gastric contractions faster than antispasmodic, consistent with reduced feeling of fullness/bloating.
- Randomised trial: Peppermint oil (menthol) pharmacokinetics in children and effects on gut motility in children with functional abdominal pain
PubMed ID: 34528282
Delayedârelease PMO in children associated with lower average abdominal pain and changes in gut contractility (exploratory).
- The combination of L-menthol and caraway oil does not affect gastric function but increases hunger in healthy subjects
PubMed ID: 39056471
Peppermint+caraway reduced epigastric burning, bloating and fullness in healthy volunteers.
- Randomized trial: Peppermint oil (menthol) pharmacokinetics in children and effects on gut motility in children with functional abdominal pain: 540âmg vs. 900âmg dose comparison
PubMed ID: 40390282
Reduced colonic contraction frequency with higher menthol exposure may reduce gasârelated symptoms.
- Does peppermint oil relieve spasm during barium enema?
PubMed ID: 7551780
Peppermint in barium enema reduced colonic spasmâmechanism consistent with reduced bloating/spasm.
- Efficacy of a fixed peppermint oil/caraway oil combination in non-ulcer dyspepsia
PubMed ID: 9006790
Entericâcoated peppermint/caraway produced large symptom improvements in dyspepsia including reduced pain/distension.
- Enteric-coated peppermint-oil capsules in the treatment of irritable bowel syndrome: a prospective, randomized trial
PubMed ID: 9430014
Large RCT (Colpermin) showed marked reductions in abdominal distension/bloating vs placebo.
- Treatment of functional dyspepsia with a fixed peppermint oil and caraway oil combination preparation as compared to cisapride. A multicenter, reference-controlled double-blind equivalence study
PubMed ID: 10604046
Peppermint+caraway equivalent to cisapride for dyspeptic symptoms, including improvements that would reduce bloating.
- [Peppermint oil-caraway oil fixed combination in non-ulcer dyspepsia--comparison of the effects of enteric preparations]
PubMed ID: 10192108
Large dyspepsia equivalence trial showed clinically relevant pain/fullness reduction (combination product).
- Efficacy and tolerability of a fixed combination of peppermint oil and caraway oil in patients suffering from functional dyspepsia
PubMed ID: 11121917
Large RCT showed significant reductions in fullness/pressure (43% vs 22%), directly relevant to bloating.
- Enteric-coated, pH-dependent peppermint oil capsules for the treatment of irritable bowel syndrome in children
PubMed ID: 11148527
High responder rate for pain in pediatric IBS may include improvements in gas symptoms though not specifically reported.
- Peppermint oil (Mintoil) in the treatment of irritable bowel syndrome: a prospective double blind placebo-controlled randomized trial
PubMed ID: 17420159
IBS trial with large symptomatic improvements including abdominal symptoms that commonly reflect bloating.
- The effect of enteric-coated, delayed-release peppermint oil on irritable bowel syndrome
PubMed ID: 19507027
Delayedârelease peppermint reduced abdominal pain and improved QoL in IBS, implying likely reduced bloating.
- A Novel Delivery System of Peppermint Oil Is an Effective Therapy for Irritable Bowel Syndrome Symptoms
PubMed ID: 26319955
Targetedârelease peppermint gave rapid, sustained IBS symptom relief including abdominal symptoms tied to bloating.
- A randomized placebo-controlled trial on the effects of Menthacarin, a proprietary peppermint- and caraway-oil-preparation, on symptoms and quality of life in patients with functional dyspepsia
PubMed ID: 28695660
Peppermint+caraway reduced dyspeptic pain/discomfortâsymptoms that overlap with bloating.
Digestive support (14)
- Efficacy and tolerability of a fixed combination of peppermint oil and caraway oil in patients suffering from functional dyspepsia
PubMed ID: 11121917
Enteric peppermint/caraway capsules significantly improved pain, fullness and global dyspepsia outcomes vs placebo.
- A randomized placebo-controlled trial on the effects of Menthacarin, a proprietary peppermint- and caraway-oil-preparation, on symptoms and quality of life in patients with functional dyspepsia
PubMed ID: 28695660
Peppermint+caraway capsule reduced pain/discomfort and improved QoL in functional dyspepsiaâsupports easier digestion.
- A Novel Delivery System of Peppermint Oil Is an Effective Therapy for Irritable Bowel Syndrome Symptoms
PubMed ID: 26319955
Targetedârelease peppermint produced rapid, sustained symptom relief in nonâconstipated IBS including abdominal symptoms tied to digestion.
- The effect of enteric-coated, delayed-release peppermint oil on irritable bowel syndrome
PubMed ID: 19507027
Delayedârelease peppermint reduced abdominal pain and improved QoL in IBSârelevant to digestive comfort.
- Peppermint oil (Mintoil) in the treatment of irritable bowel syndrome: a prospective double blind placebo-controlled randomized trial
PubMed ID: 17420159
Entericâcoated peppermint significantly improved IBS symptom scoresâconsistent with calmer/easier digestion.
- Peppermint oil reduces gastric spasm during upper endoscopy: a randomized, double-blind, double-dummy controlled trial
PubMed ID: 12665756
Peppermint solution relaxed the stomach faster/better than standard antispasmodic during endoscopyâpractical antispasmodic/digestive benefit.
- Multicenter phase II randomized study evaluating dose-response of antiperistaltic effect of L-menthol sprayed onto the gastric mucosa for upper gastrointestinal endoscopy
PubMed ID: 22348831
Lâmenthol sprayed on gastric mucosa doseâdependently suppressed gastric peristalsisâuseful endoscopically and shows GI pharmacologic activity.
- Randomised trial: Peppermint oil (menthol) pharmacokinetics in children and effects on gut motility in children with functional abdominal pain
PubMed ID: 34528282
Delayedârelease peppermint oil in children altered gut contractility and associated with lower abdominal pain (digestive symptom benefit).
- Randomized trial: Peppermint oil (menthol) pharmacokinetics in children and effects on gut motility in children with functional abdominal pain: 540âmg vs. 900âmg dose comparison
PubMed ID: 40390282
Doseârelated reductions in colonic and wholeâgut contraction frequency with menthol exposure indicate modulation of gut motility.
- Does peppermint oil relieve spasm during barium enema?
PubMed ID: 7551780
Peppermint reduced colonic spasm during barium enema, demonstrating smoothâmuscle relaxant GI effects relevant to digestion.
- Efficacy of a fixed peppermint oil/caraway oil combination in non-ulcer dyspepsia
PubMed ID: 9006790
Entericâcoated peppermint/caraway markedly improved pain and overall symptoms in nonâulcer dyspepsiaâclinically meaningful digestive benefit.
- Enteric-coated peppermint-oil capsules in the treatment of irritable bowel syndrome: a prospective, randomized trial
PubMed ID: 9430014
Large RCT (Colpermin) significantly improved abdominal pain, distension and other IBS symptoms (digestive symptom relief).
- Treatment of functional dyspepsia with a fixed peppermint oil and caraway oil combination preparation as compared to cisapride. A multicenter, reference-controlled double-blind equivalence study
PubMed ID: 10604046
Peppermint/caraway was equivalent to cisapride for functional dyspepsia, showing strong benefit for digestive symptoms.
- [Peppermint oil-caraway oil fixed combination in non-ulcer dyspepsia--comparison of the effects of enteric preparations]
PubMed ID: 10192108
Large multicenter trial showed enteric peppermint/caraway reduced dyspepsia pain and frequencyâclinically relevant for digestion comfort.
Pain relief (4)
- The effects of peppermint gel on prevention of pressure injury in hospitalized patients with head trauma in neurosurgical ICU: A double-blind randomized controlled trial
PubMed ID: 31780037
Topical peppermint gel reduced pressure injuries and likely produced soothing/cooling local effects on skin and underlying tissues.
- Effect of peppermint and eucalyptus oil preparations on neurophysiological and experimental algesimetric headache parameters
PubMed ID: 7954745
Topical peppermint+ethanol reduced headache sensitivity in healthy volunteers and improved relaxation measures.
- The effect of aromatherapy massage with peppermint oil on functional impairments in patients with knee osteoarthritis
PubMed ID: 40925064
Randomized trial: peppermint oil aromatherapy massage significantly reduced knee pain and improved function in knee osteoarthritisâdirectly supports musculoskeletal comfort.
- [Effectiveness of Oleum menthae piperitae and paracetamol in therapy of headache of the tension type]
PubMed ID: 8805113
Randomized doubleâblind crossover: 10% topical peppermint oil reduced tensionâtype headache pain within 15 minutes, similar to 1 g acetaminophen.
Mood balance (3)
- Effect of inhalation of peppermint essential oil aromatherapy on postoperative delirium in old patients following major lower limb joint arthroplasty surgery: A randomized controlled trial
PubMed ID: 41390992
Peppermint inhalation lowered postoperative anxiety scores and pain, supporting a moderate moodâuplifting effect in this setting.
- Effects of inhalation of peppermint oil after lumbar discectomy surgery on pain and anxiety levels of patients: A randomized controlled study
PubMed ID: 38072763
Postâop inhalation reduced anxiety and pain at later timepointsâconsistent with modest mood benefit.
- The effect of aromatherapy massage with lemon and peppermint essential oil on menopausal symptoms: A double-blinded, randomized placebo controlled clinical trial
PubMed ID: 37743153
Aromatherapy massage with peppermint reduced overall menopausal symptom scores (somatic/urogenital); mood improvements plausible though massage confounds attribution.
Mental clarity (3)
- Effect of inhalation of peppermint essential oil aromatherapy on postoperative delirium in old patients following major lower limb joint arthroplasty surgery: A randomized controlled trial
PubMed ID: 41390992
Large RCT showed a meaningful absolute reduction in early postoperative delirium with inhaled peppermintâstrong evidence for improved acute mental clarity.
- Effects of inhalation of peppermint oil after lumbar discectomy surgery on pain and anxiety levels of patients: A randomized controlled study
PubMed ID: 38072763
Inhaled peppermint after lumbar surgery reduced pain and anxiety at 3â4 h; may modestly improve subjective clarity in early postoperative period.
- Effect of peppermint and eucalyptus oil preparations on neurophysiological and experimental algesimetric headache parameters
PubMed ID: 7954745
Topical peppermint/eucalyptus improved cognitive performance measures in a crossover study.
Skin soothing (3)
- Effect of peppermint and eucalyptus oil preparations on neurophysiological and experimental algesimetric headache parameters
PubMed ID: 7954745
Topical peppermint preparations produced sensory/trigeminal effects consistent with cooling skin sensation in volunteers.
- Effective symptomatic treatment for severe and intractable pruritus associated with severe burn-induced hypertrophic scars: A prospective, multicenter, controlled trial
PubMed ID: 27207739
Hydrogel containing peppermint/menthol reduced severe scar itch; multiâingredient product but cooling/menthol likely contributed.
- The effects of peppermint gel on prevention of pressure injury in hospitalized patients with head trauma in neurosurgical ICU: A double-blind randomized controlled trial
PubMed ID: 31780037
Topical peppermint gel applied to ICU patients produced large protective effects on skin; topical menthol/peppermint reliably produces cooling sensation.
Focus & concentration (2)
- Effect of peppermint and eucalyptus oil preparations on neurophysiological and experimental algesimetric headache parameters
PubMed ID: 7954745
Crossover study showed improved cognitive performance with topical peppermint/eucalyptus.
- Effect of inhalation of peppermint essential oil aromatherapy on postoperative delirium in old patients following major lower limb joint arthroplasty surgery: A randomized controlled trial
PubMed ID: 41390992
Reduced delirium and lower anxiety after inhaled peppermint implies improved shortâterm attentional function in hospitalized elders.
Oral health (2)
- The effect of different essential oils used in stoma bags of individuals with colostomy remooval of odor, life satisfaction and effect on stoma fit: Randomized controlled study
PubMed ID: 39418824
Placing peppermint oil in colostomy bags reduced odor and improved life satisfactionâclear odor control effect in a pouch context.
- Prevention of radiotherapy-related oral mucositis with zinc and polyherbal mouthwash: a double-blind, randomized clinical trial
PubMed ID: 36864527
Polyherbal mouthwash containing peppermint oil reduced oral mucositis severity and pain vs placebo (multiple ingredients, effect not solely peppermint).
Appetite suppression (1)
- The combination of L-menthol and caraway oil does not affect gastric function but increases hunger in healthy subjects
PubMed ID: 39056471
Peppermint+caraway increased fasting hunger and reduced satiety in healthy volunteers, demonstrating a measurable effect on appetite.
Similar by evidence
Supplements the same benefits carry qualifying findings for â a fact about the evidence graph, not a recommendation to swap.
Products with Peppermint Oil
Search all137 products whose verified label declares Peppermint Oil â not every bottle that mentions it in a title.