Nettle
5 benefits mapped to clinical evidence across supplements.
Dose per serving from products
179 products in our catalogue print how much Nettle a serving holds.
Most common: 25 mg to 50 mg, 54% of 179 products.
| Dose per serving | Products |
|---|---|
| 10 mg or less | 9 |
| 10 mg to 25 mg | 8 |
| 25 mg to 50 mg | 97 |
| 50 mg to 100 mg | 19 |
| 100 mg to 250 mg | 23 |
| 250 mg to 500 mg | 7 |
| 500 mg to 1 g | 15 |
| over 1 g | 1 |
Dose per serving from research
12 study groups in 9 studies say how much Nettle participants took a day.
These are the doses the studies gave. They are not a recommendation.
Most common: 250 mg to 500 mg, 42% of 12 study groups.
| Daily dose | Study groups |
|---|---|
| 100 mg to 250 mg | 3 |
| 250 mg to 500 mg | 5 |
| 500 mg to 1 g | 2 |
| 1 g to 2.5 g | 2 |
Benefit Evidence
Research sources
Urinary comfort (11)
- Serenoa repens associated with Urtica dioica (ProstaMEV) and curcumin and quercitin (FlogMEV) extracts are able to improve the efficacy of prulifloxacin in bacterial prostatitis patients: results from a prospective randomised study
PubMed ID: 19181486
Prospective randomized study: addition of Urtica-containing phytotherapeutic to antibiotics improved symptoms and QoL in chronic prostatitisârelevant to urinary/prostate comfort though a multi-component product.
- Combined extracts of Urtica dioica and Pygeum africanum in the treatment of benign prostatic hyperplasia: double-blind comparison of two doses
PubMed ID: 7509261
Fixed combination (nettle root + Pygeum) showed urinary symptom improvements; supports urinary benefit but attribution to nettle alone is uncertain.
- Combined sabal and urtica extract compared with finasteride in men with benign prostatic hyperplasia: analysis of prostate volume and therapeutic outcome
PubMed ID: 10971268
Large trial of saw palmetto + nettle performed similarly to finasteride for BPH symptomsâsupports symptomatic urinary benefit within a combination product.
- [Stinging nettle root extract (Bazoton-uno) in long term treatment of benign prostatic syndrome (BPS). Results of a randomized, double-blind, placebo controlled multicenter study after 12 months]
PubMed ID: 15045190
12-month randomized trial of nettle root extract alone with statistically significant IPSS improvementâgood long-term clinical evidence for urinary symptom relief.
- Long-term efficacy and safety of a combination of sabal and urtica extract for lower urinary tract symptoms--a placebo-controlled, double-blind, multicenter trial
PubMed ID: 15928959
Multicenter RCT of sabal+urtica demonstrating clinically meaningful I-PSS improvement vs placeboâsupports benefit though nettle was combined with saw palmetto.
- Urtica dioica for treatment of benign prostatic hyperplasia: a prospective, randomized, double-blind, placebo-controlled, crossover study
PubMed ID: 16635963
Large RCT of nettle root showing substantial, objective improvements in IPSS, Qmax and postvoid residualâstrong direct evidence for urinary symptom benefit.
- [Efficacy of a combined Sabal-urtica preparation in the symptomatic treatment of benign prostatic hyperplasia. Results of a placebo-controlled double-blind study]
PubMed ID: 16261945
Re-analysis showing PRO160/120 (sabal+urtica) reduced urgency/frequency and improved QoLâsupports urinary symptom relief within combination.
- [Combined extract of Sabal palm and nettle in the treatment of patients with lower urinary tract symptoms in double blind, placebo-controlled trial]
PubMed ID: 16708583
Double-blind trial of saw palmetto + nettle showing LUTS improvement and good tolerabilityâcombination evidence supports urinary comfort.
- Efficacy and safety of a combination of Sabal and Urtica extract in lower urinary tract symptoms--long-term follow-up of a placebo-controlled, double-blind, multicenter trial
PubMed ID: 18038253
Large trial showing clinically meaningful improvements in prostate/urinary symptoms with a fixed saw palmetto + nettle combination; nettle-specific contribution uncertain but benefits apply to urinary comfort.
- Fixed-dose combination PRO 160/120 of sabal and urtica extracts improves nocturia in men with LUTS suggestive of BPH: re-evaluation of four controlled clinical studies
PubMed ID: 24938176
Pooled analysis of saw palmetto + nettle combo showed reduced nocturia vs placebo; meaningful urinary comfort effect though combination product limits nettle attribution.
- Urtica Dioica Root Extract on Clinical and Biochemical Parameters in Patients with Benign Prostatic Hyperplasia, Randomized Controlled Trial
PubMed ID: 32981268
Randomized trial of Urtica dioica root extract improved IPSS and urinary symptoms â direct nettle root evidence for urinary benefit.
Inflammation (3)
- A Rosa canina - Urtica dioica - Harpagophytum procumbens/zeyheri Combination Significantly Reduces Gonarthritis Symptoms in a Randomized, Placebo-Controlled Double-Blind Study
PubMed ID: 28614869
Rosehip/nettle/devil's-claw formulation reduced OA pain and improved functionâconsistent with anti-inflammatory/analgesic effects within a combination product.
- Phytalgic, a food supplement, vs placebo in patients with osteoarthritis of the knee or hip: a randomised double-blind placebo-controlled clinical trial
PubMed ID: 20015358
Nutraceutical containing nettle reduced NSAID use and improved OA symptoms, implying anti-inflammatory/analgesic benefit for the formulation.
- The effect of hydro alcoholic Nettle (Urtica dioica) extracts on insulin sensitivity and some inflammatory indicators in patients with type 2 diabetes: a randomized double-blind control trial
PubMed ID: 22303583
Randomized trial showed reductions in ILâ6 and hsâCRP in diabetics after nettle extract, supporting antiâinflammatory activity.
Joint comfort (2)
- A Rosa canina - Urtica dioica - Harpagophytum procumbens/zeyheri Combination Significantly Reduces Gonarthritis Symptoms in a Randomized, Placebo-Controlled Double-Blind Study
PubMed ID: 28614869
12-week double-blind RCT of a rosehip/nettle/devil's-claw formulation showed reduced knee OA pain and improved function versus placeboâsupports symptom relief within a combination.
- Phytalgic, a food supplement, vs placebo in patients with osteoarthritis of the knee or hip: a randomised double-blind placebo-controlled clinical trial
PubMed ID: 20015358
Three-month randomized DBRCT of a nutraceutical (fish oils, nettle, zinc, vit E) reduced analgesic/NSAID use and improved WOMAC scores in OAâbenefit shown for the multi-ingredient product including nettle.
Blood sugar (2)
- Improved glycemic control in patients with advanced type 2 diabetes mellitus taking Urtica dioica leaf extract: a randomized double-blind placebo-controlled clinical trial
PubMed ID: 24273930
Randomized double-blind placebo-controlled trial of nettle leaf extract in insulin-treated T2DM showing significant reductions in fasting glucose, postprandial glucose and HbA1câstrong direct evidence.
- Silymarin, Olibanum, and Nettle, A Mixed Herbal Formulation in the Treatment of Type II Diabetes: A Randomized, Double-Blind, Placebo-Controlled, Clinical Trial
PubMed ID: 29228792
Randomized DBRCT showing improved fasting glucose and HbA1c but used a fixed combination (silymarin, frankincense, nettle), so effect cannot be attributed solely to nettle.
Antioxidant (2)
- The effect of hydro alcoholic nettle (Urtica dioica) extract on oxidative stress in patients with type 2 diabetes: a randomized double-blind clinical trial
PubMed ID: 22545363
Randomized trial in people with T2DM showed Urtica dioica extract increased total antioxidant capacity and SOD vs controlâdirect biomarker evidence of antioxidant support.
- Urtica Dioica Root Extract on Clinical and Biochemical Parameters in Patients with Benign Prostatic Hyperplasia, Randomized Controlled Trial
PubMed ID: 32981268
Nettle root extract trial reported decreased MDA and increased SOD activity, indicating antioxidant effects.
Similar by evidence
Supplements the same benefits carry qualifying findings for â a fact about the evidence graph, not a recommendation to swap.
Products with Nettle
Search all595 products whose verified label declares Nettle â not every bottle that mentions it in a title.