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Hyaluronic Acid

13 benefits mapped to clinical evidence across supplements.

Serves the goals:Bone & JointEssential HealthFitnessHair & SkinLongevity

Benefit Evidence

Joint comfort
Strong

Pain↓ Function↑

Pain↓ Function↑

36,295 people
Joint mobility
Strong

Knee pain/function -30%

Jaw opening/pain +

28,454 people
Skin hydration
Strong

Hydration +6.4%

Barrier/moisture +10.6%

19,830 people
Skin appearance
Strong

Wrinkles/hydration +1.0

Firmness/density +15%

Volume/folds -7.6d

17,906 people
Joints & tendons
Strong

Joints: pain/function +30%

Tendons: gliding −friction

Cartilage: biomarker ↓

21,337 people
Healthy aging
Strong

Wrinkles+higher satisfaction

Hydration+firmness+density

+15% / +22%

15,710 people
Skin repair
Strong

Healing faster +7.6d

Adhesions lower +23%

Collagen/wrinkles +12%

10,853 people
Hydration
Strong

Dryness relief + hydration

Tear stability, staining

10,923 people
Eye health
Strong

Staining/symptoms -3 pts

Tear stability/production +2s

Corneal healing +

9,574 people
Exercise recovery
Strong

Less pain, faster recovery

+23pp adhesions

-7.6d healing

8,939 people
Skin soothing
Strong

Healing + pain ↓

Adhesions/inflammation ↓

6,119 people
Oral health
Moderate

Mucositis ↓ severity/duration

Xerostomia ↓, saliva ↑

504 people
Hair & Nails
Weak

Hair density +91/ncm²

Wrinkle depth, evenness

88 people

Forms of Hyaluronic Acid

The form a label may print instead of Hyaluronic Acid. Each is a different substance with its own identifier, and none of them has research of its own — the studies are the ones on this page.

Sodium Hyaluronate

A salt or solvate of Hyaluronic Acid.

Similar by evidence

Supplements the same benefits carry qualifying findings for — a fact about the evidence graph, not a recommendation to swap.

Collagen

Shares 9 benefits: exercise recovery, hair & nails, healthy aging, joint comfort

Silica

Shares 9 benefits: hair & nails, healthy aging, hydration, joint comfort

Vitamin C

Shares 8 benefits: exercise recovery, hair & nails, healthy aging, joint comfort

Vitamin E

Shares 7 benefits: exercise recovery, eye health, hair & nails, healthy aging

L-Proline

Shares 6 benefits: exercise recovery, healthy aging, joint comfort, joints & tendons

Grape Seed Extract

Shares 6 benefits: exercise recovery, eye health, healthy aging, joints & tendons

Products with Hyaluronic Acid

Search all

945 products whose verified label declares Hyaluronic Acid — not every bottle that mentions it in a title.

Clean Nutraceuticals

Creatine for Women

Vitamin D (as cholecalciferol) 100 mcg ¡ Folate (as methyltetrahydrofolate) 400 mcg ¡ Biotin 10000 mcg +22 more

$32.95Creatine

Osteo Bi-Flex

Osteo Bi-Flex Triple Strength Glucosamine Chondroitin Supplement

Vitamin C 60 mg ¡ Manganese 2 mg ¡ Glucosamine HCl 1500 mg +8 more

$13.79Diet & Sports Nutrition

Osteo Bi-Flex

Osteo Bi-Flex Triple Strength Glucosamine Chondroitin Supplement

Vitamin C 60 mg ¡ Manganese 2 mg ¡ Glucosamine HCl 1500 mg +8 more

$24.44Chondroitin

Dr. Berg Nutritionals

Dr. Berg Multi Collagen Peptides Powder Types I, II, III, V, X

Vitamin C 90 mg ¡ Biotin 60 mcg ¡ Proprietary Blend 15.587 g +5 more

$37.99Collagen

Nature's Way

Nature's Way Joint Movement Glucosamine Liquid, Chondroitin, Berry

Vitamin D3 10 mcg ¡ Glucosamine Hydrochloride 2000 mg ¡ Chondroitin Sulfate 1200 mg +2 more

$14.99Chondroitin

Move Free

Move Free Advanced Joint Support, Glucosamine, Chondroitin + MSM

$19.99Combinations

Being studied right now

Recruiting clinical trials registered on ClinicalTrials.gov. A trial in progress has no result yet — this is what the field is asking, not what it found.

Low EnerGy DiEt iN Adolescents With Obesity and Type 2 Diabetes: The LEGEND StudyHyaluronic Acid ¡ Pediatric Obesity, Type 2 Diabetes ¡ 73 participants planned ¡ ClinicalTrials.govRecruitingComparison of Steroid, PRP,and PRP Plus Hyaluronic Acid Injection for Rotator Cuff Lesions.Hyaluronic Acid ¡ Rotator Cuff Lesions ¡ 80 participants planned ¡ ClinicalTrials.govRecruiting