D-Limonene
5 benefits mapped to clinical evidence across supplements.
Benefit Evidence
Research sources
Respiratory comfort (1)
- Efficacy and tolerability of myrtol standardized in acute bronchitis. A multi-centre, randomised, double-blind, placebo-controlled parallel group clinical trial vs. cefuroxime and ambroxol
PubMed ID: 10994153
Large randomized trial: myrtol (contains d‑limonene) produced substantially higher responder rates in acute bronchitis versus placebo — strong clinical respiratory benefit for the multicomponent product.
Oral health (1)
- Effect of toothpaste containing d-limonene on natural extrinsic smoking stain: a 4-week clinical trial
PubMed ID: 21250568
Large randomized double‑blind trial: toothpaste with 5% d‑limonene plus perlite significantly improved removal and prevention of tobacco stains — clear consumer oral/cosmetic benefit.
Inflammation (1)
- Impact of diet and nutraceutical supplementation on inflammation in elderly people. Results from the RISTOMED study, an open-label randomized control trial
PubMed ID: 26249791
d‑Limonene supplementation in a diet trial was associated with decreased fibrinogen and other inflammatory markers, supporting an anti‑inflammatory effect.
Metabolism (1)
- Impact of diet and nutraceutical supplementation on inflammation in elderly people. Results from the RISTOMED study, an open-label randomized control trial
PubMed ID: 26249791
In older adults, supplementation with d‑limonene (within a diet trial) was linked to improved fasting glucose, insulin and HOMA‑IR, indicating meaningful metabolic effects.
Digestive support (1)
- Efficacy and safety of a food supplement with standardized menthol, limonene, and gingerol content in patients with irritable bowel syndrome: A double-blind, randomized, placebo-controlled trial
PubMed ID: 35704960
Randomized human trial of a menthol–limonene–gingerol supplement produced a clinically meaningful reduction in IBS symptom scores; limonene-specific contribution uncertain (multicomponent).
Similar by evidence
Supplements the same benefits carry qualifying findings for — a fact about the evidence graph, not a recommendation to swap.
Products with D-Limonene
Search all24 products whose verified label declares D-Limonene — not every bottle that mentions it in a title.
Being studied right now
Recruiting clinical trials registered on ClinicalTrials.gov. A trial in progress has no result yet — this is what the field is asking, not what it found.