supp.fit

Cat's Claw

4 benefits mapped to clinical evidence across supplements.

Dose per serving from products

216 products in our catalogue print how much Cat's Claw a serving holds.

Most common: 25 mg to 50 mg, 69% of 216 products.

Dose per servingProducts
25 mg or less
8
25 mg to 50 mg
148
50 mg to 100 mg
19
100 mg to 250 mg
11
250 mg to 500 mg
12
500 mg to 1 g
13
over 1 g
5

Benefit Evidence

Pain, joints ↓53%

TNF-alpha inhibition

85 people

Pain -53% joints

Assessment scores improved

85 people

Stomatitis severity down; similar to miconazole

Candida counts down

50 people

Pain, scores ↓

TNF-alpha inhibition

45 people

Research sources

Inflammation (2)
  1. Efficacy and safety of freeze-dried cat's claw in osteoarthritis of the knee: mechanisms of action of the species Uncaria guianensis

    PubMed ID: 11603848

    Clinical pain reduction in knee trial and in vitro TNF-alpha inhibition indicate anti-inflammatory activity.

  2. Randomized double blind trial of an extract from the pentacyclic alkaloid-chemotype of uncaria tomentosa for the treatment of rheumatoid arthritis

    PubMed ID: 11950006

    RA trial demonstrated reductions in tender/swollen joints consistent with reduced inflammatory activity over 24 weeks.

Joint comfort (2)
  1. Efficacy and safety of freeze-dried cat's claw in osteoarthritis of the knee: mechanisms of action of the species Uncaria guianensis

    PubMed ID: 11603848

    Four-week randomized trial showed reduced activity-related knee pain and better assessment scores—direct symptomatic joint benefit.

  2. Randomized double blind trial of an extract from the pentacyclic alkaloid-chemotype of uncaria tomentosa for the treatment of rheumatoid arthritis

    PubMed ID: 11950006

    24-week RCT in rheumatoid arthritis showed substantial reductions in tender (and some swollen) joint counts—strong clinical joint evidence.

Skin health (1)
  1. Evaluation of different treatment methods against denture stomatitis: a randomized clinical study

    PubMed ID: 24908596

    Topical Uncaria tomentosa gel reduced denture stomatitis severity comparable to miconazole—supports mucocutaneous health.

Antioxidant (1)
  1. Efficacy and safety of freeze-dried cat's claw in osteoarthritis of the knee: mechanisms of action of the species Uncaria guianensis

    PubMed ID: 11603848

    Study reported antioxidant activity in vitro alongside clinical pain benefit—supportive but mostly preclinical data.

Similar by evidence

Supplements the same benefits carry qualifying findings for — a fact about the evidence graph, not a recommendation to swap.

Products with Cat's Claw

Search all

476 products whose verified label declares Cat's Claw — not every bottle that mentions it in a title.

Being studied right now

Recruiting clinical trials registered on ClinicalTrials.gov. A trial in progress has no result yet — this is what the field is asking, not what it found.