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Bitter Melon

7 benefits mapped to clinical evidence across supplements.

Dose per serving from products

190 products in our catalogue print how much Bitter Melon a serving holds.

Most common: 25 mg to 50 mg and 50 mg to 100 mg, 22% of 190 products each.

Dose per servingProducts
10 mg or less
10
10 mg to 25 mg
23
25 mg to 50 mg
42
50 mg to 100 mg
42
100 mg to 250 mg
32
250 mg to 500 mg
24
500 mg to 1 g
9
over 1 g
8

Dose per serving from research

10 study groups in 7 studies say how much Bitter Melon participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 1 g to 2.5 g, 60% of 10 study groups.

Daily doseStudy groups
250 mg to 500 mg
1
500 mg to 1 g
1
1 g to 2.5 g
6
2.5 g to 5 g
2

See every study group

Benefit Evidence

Blood sugar
Moderate

Lower fasting glucose

HbA1c -1.15%

447 people
Metabolism
Moderate

Glucose control -15%

Insulin secretion +577.9

372 people

Glucose control, -1.15% HbA1c

Insulin resistance, lower FPG

163 people

TG ↓ -14 mg/dL

VLDL ↓ -0.1 mM

95 people

Triglycerides -14 mg/dL

HbA1c -1.15%

95 people

Pain/analgesic ↓

Glucose/weight ↓

75 people

Pain relief, -weight

Glucose drop, less analgesics

75 people

Research sources

Blood sugar (6)
  1. The effects of Momordica charantia (bitter melon) supplementation in patients with primary knee osteoarthritis: A single-blinded, randomized controlled trial

    PubMed ID: 30057048

    Knee OA trial reported reduced fasting glucose in bitter melon group—supports glycemic benefit in a clinical setting.

  2. Investigation of the Influence of a Bitter Melon Product on Indicators of Cardiometabolic Health in Adults with Prediabetes

    PubMed ID: 39536276

    12‑week prediabetes trial blunted increases in fasting glucose versus control—protective glycemic effect.

  3. Lower hypoglycemic but higher antiatherogenic effects of bitter melon than glibenclamide in type 2 diabetic patients

    PubMed ID: 25623883

    10‑week RCT showed clinically meaningful reductions in HbA1c and fasting glucose versus baseline/placebo.

  4. Bitter gourd (Momordica charantia L.) supplementation for twelve weeks improves biomarkers of glucose homeostasis in a prediabetic population

    PubMed ID: 40199408

    Controlled trials (incl. 12‑week) reported reductions in fasting glucose, fasting insulin and HOMA‑IR in prediabetics.

  5. Bitter gourd reduces elevated fasting plasma glucose levels in an intervention study among prediabetics in Tanzania

    PubMed ID: 29339109

    8‑week crossover in prediabetics lowered fasting glucose by ~5.6 mg/dL—significant glycemic effect.

  6. Hypoglycemic efficacy and safety of Momordica charantia (bitter melon) in patients with type 2 diabetes mellitus

    PubMed ID: 32951763

    12‑week RCT lowered fasting glucose (but not HbA1c)—modest glycemic benefit.

Metabolism (5)
  1. Bitter gourd (Momordica charantia L.) supplementation for twelve weeks improves biomarkers of glucose homeostasis in a prediabetic population

    PubMed ID: 40199408

    Controlled trials showing improved FPG, fasting insulin and HOMA‑IR in prediabetics provide robust metabolic support.

  2. Lower hypoglycemic but higher antiatherogenic effects of bitter melon than glibenclamide in type 2 diabetic patients

    PubMed ID: 25623883

    Randomized trial showed improvements in HbA1c, fasting glucose and triglycerides—strong metabolic evidence.

  3. Bitter gourd reduces elevated fasting plasma glucose levels in an intervention study among prediabetics in Tanzania

    PubMed ID: 29339109

    Prediabetes crossover trial lowered fasting glucose—meaningful metabolic impact.

  4. Hypoglycemic efficacy and safety of Momordica charantia (bitter melon) in patients with type 2 diabetes mellitus

    PubMed ID: 32951763

    12‑week RCT lowered fasting glucose though HbA1c unchanged—moderate metabolic support.

  5. Investigation of the Influence of a Bitter Melon Product on Indicators of Cardiometabolic Health in Adults with Prediabetes

    PubMed ID: 39536276

    Blunted fasting glucose increase in prediabetics suggests protective metabolic action.

Wellbeing (2)
  1. Lower hypoglycemic but higher antiatherogenic effects of bitter melon than glibenclamide in type 2 diabetic patients

    PubMed ID: 25623883

    Broad metabolic improvements (HbA1c, FPG, TG) in a randomized trial suggest general wellness benefits.

  2. Bitter gourd (Momordica charantia L.) supplementation for twelve weeks improves biomarkers of glucose homeostasis in a prediabetic population

    PubMed ID: 40199408

    Controlled trials showing improvements in FPG, insulin and HOMA‑IR support broader metabolic wellness.

Cholesterol (1)
  1. Lower hypoglycemic but higher antiatherogenic effects of bitter melon than glibenclamide in type 2 diabetic patients

    PubMed ID: 25623883

    10‑week RCT reduced triglycerides (though other cholesterol fractions less clear)—supports healthier lipid profile.

Heart health (1)
  1. Lower hypoglycemic but higher antiatherogenic effects of bitter melon than glibenclamide in type 2 diabetic patients

    PubMed ID: 25623883

    Reduced triglycerides in 10-week RCT—favors cardiovascular risk profile.

Inflammation (1)
  1. The effects of Momordica charantia (bitter melon) supplementation in patients with primary knee osteoarthritis: A single-blinded, randomized controlled trial

    PubMed ID: 30057048

    Improved pain and reduced analgesic use in osteoarthritis suggest possible anti‑inflammatory or analgesic effects.

Weight management (1)
  1. The effects of Momordica charantia (bitter melon) supplementation in patients with primary knee osteoarthritis: A single-blinded, randomized controlled trial

    PubMed ID: 30057048

    3‑month trial in knee OA reported modest weight reduction in bitter melon group.

Similar by evidence

Supplements the same benefits carry qualifying findings for — a fact about the evidence graph, not a recommendation to swap.

Products with Bitter Melon

Search all

426 products whose verified label declares Bitter Melon — not every bottle that mentions it in a title.

Being studied right now

Recruiting clinical trials registered on ClinicalTrials.gov. A trial in progress has no result yet — this is what the field is asking, not what it found.