Artemisia Annua
9 benefits mapped to clinical evidence across supplements.
Dose per serving from research
6 study groups in 4 studies say how much Artemisia Annua participants took a day.
These are the doses the studies gave. They are not a recommendation.
Most common: 250 mg to 500 mg and 2.5 g to 5 g, 33% of 6 study groups each.
| Daily dose | Study groups |
|---|---|
| 250 mg to 500 mg | 2 |
| 500 mg to 1 g | 1 |
| 1 g to 2.5 g | 0 |
| 2.5 g to 5 g | 2 |
| 5 g to 10 g | 0 |
| 10 g to 25 g | 0 |
| over 25 g | 1 |
Benefit Evidence
Research sources
Wellbeing (10)
- Artemisia annua-sublingual immunotherapy for seasonal allergic rhinitis: A randomized controlled trial
PubMed ID: 32030780
SLIT reduced allergy symptom scores and produced immunologic tolerance markers, likely improving daily comfort/quality of life.
- Clinical Efficacy and Safety of Artesimia annua-Sublingual Immunotherapy in Seasonal Allergic Rhinitis Patients Based on Different Intervention Time
PubMed ID: 35413714
Randomized SLIT reduced combined symptom+medication scores during pollen seasons, indicating improved seasonal quality of life.
- Clinical efficacy in one-year treatment with Artemisia annua-SLIT drops in monosensitized and polysensitized individuals
PubMed ID: 37478537
One-year SLIT trial delivered clinically meaningful reductions in symptoms and medication use with good tolerability, supporting wellbeing.
- Evaluation of the effects of Artemisia Annua L. and Moringa Oleifera Lam. on CD4 count and viral load among PLWH on ART at Mbarara Regional Referral Hospital: a double-blind randomized controlled clinical trial
PubMed ID: 38627722
Increased CD4 counts and improved viral suppression with Artemisia (±Moringa) point to meaningful clinical and wellbeing improvements in people with HIV.
- Coseasonal initiation of Artemisia annua sublingual immunotherapy in children and adult patients with allergic rhinoconjunctivitis
PubMed ID: 39611955
One-year pediatric/adult SLIT trial showed significant symptom and medication score reductions, consistent with improved wellbeing.
- A pilot randomized, placebo-controlled clinical trial to investigate the efficacy and safety of an extract of Artemisia annua administered over 12 weeks, for managing pain, stiffness, and functional limitation associated with osteoarthritis of the hip and knee
PubMed ID: 26631103
Pilot OA trial showed clinically relevant reductions in pain/stiffness at the lower dose, indicating improved daily function and wellbeing.
- Effect of Artemisia annua extract on treating active rheumatoid arthritis: A randomized controlled trial
PubMed ID: 28035541
Adjunctive extract improved RA symptoms/function and reduced inflammatory markers, suggesting meaningful improvement in patient wellbeing.
- An open-label six-month extension study to investigate the safety and efficacy of an extract of Artemisia annua for managing pain, stiffness and functional limitation associated with osteoarthritis of the hip and knee
PubMed ID: 27806033
Open-label extension maintained WOMAC improvements and demonstrated continued tolerability, consistent with sustained wellbeing benefits.
- Artemisia annua and Artemisia afra tea infusions vs. artesunate-amodiaquine (ASAQ) in treating Plasmodium falciparum malaria in a large scale, double blind, randomized clinical trial
PubMed ID: 30668322
Large malaria RCT reported faster clinical recovery, higher cure rates, less gametocyte carriage and far fewer adverse events — major overall benefit.
- Effect of Artemisia annua and Artemisia afra tea infusions on schistosomiasis in a large clinical trial
PubMed ID: 30466622
Schistosomiasis trial produced faster egg clearance, hematologic recovery and fewer AEs vs praziquantel, improving patient recovery/wellbeing.
Immune support (7)
- Artemisia annua and Artemisia afra tea infusions vs. artesunate-amodiaquine (ASAQ) in treating Plasmodium falciparum malaria in a large scale, double blind, randomized clinical trial
PubMed ID: 30668322
Large RCT showing faster parasite and fever clearance and lower gametocyte carriage implies indirect immune-relevant outcomes via pathogen control.
- Coseasonal initiation of Artemisia annua sublingual immunotherapy in children and adult patients with allergic rhinoconjunctivitis
PubMed ID: 39611955
Year-long SLIT in children/adults reduced symptoms/medication use with good safety and implied immune tolerance effects.
- Effect of Artemisia annua extract on treating active rheumatoid arthritis: A randomized controlled trial
PubMed ID: 28035541
Adjunct A. annua extract in RA improved inflammatory markers (CRP/ESR/RF/CCP-Ab) and clinical disease measures, reflecting immune-modulating effects.
- Artemisia annua-sublingual immunotherapy for seasonal allergic rhinitis: A randomized controlled trial
PubMed ID: 32030780
Sublingual immunotherapy altered T‑cell subsets (↓Th2, ↑nTreg/Tr1), indicating immunomodulatory/tolerance-promoting effects.
- Clinical Efficacy and Safety of Artesimia annua-Sublingual Immunotherapy in Seasonal Allergic Rhinitis Patients Based on Different Intervention Time
PubMed ID: 35413714
Randomized SLIT study showed clinical improvement and reported immunologic effects consistent with immune modulation.
- Clinical efficacy in one-year treatment with Artemisia annua-SLIT drops in monosensitized and polysensitized individuals
PubMed ID: 37478537
One-year SLIT trial produced symptom/medication reductions and immunologic tolerance across sensitization statuses, supporting immune modulation.
- Evaluation of the effects of Artemisia Annua L. and Moringa Oleifera Lam. on CD4 count and viral load among PLWH on ART at Mbarara Regional Referral Hospital: a double-blind randomized controlled clinical trial
PubMed ID: 38627722
RCT in ART-treated patients showed significant CD4 increases and improved viral suppression over 12 months, indicating immune benefit.
Antimicrobial (5)
- Effects of Artemisia annua and Foeniculum vulgare on chickens highly infected with Eimeria tenella (phylum Apicomplexa)
PubMed ID: 24731599
Controlled chicken trial: leaf powder markedly reduced oocyst shedding (≈88% reduction) and lesion scores against E. tenella, strong anticoccidial effect (animal).
- Use of Artemisia annua as a natural coccidiostat in free-range broilers and its effects on infection dynamics and performance
PubMed ID: 22154969
Feeding dried A. annua leaves to broilers lowered parasite egg shedding significantly, though growth effects varied by genotype/sex.
- Anticoccidial effects of Artemisia annua ethanolic extract: prevention, simultaneous challenge-medication, and treatment
PubMed ID: 28766151
Ethanolic extract in chicks significantly reduced oocyst output and improved weight gain, especially as preventive—strong animal anticoccidial effect.
- Artemisia annua and Artemisia afra tea infusions vs. artesunate-amodiaquine (ASAQ) in treating Plasmodium falciparum malaria in a large scale, double blind, randomized clinical trial
PubMed ID: 30668322
Large double-blind RCT found Artemisia infusions cured falciparum malaria faster and more completely (D28 cure 96.4% for A. annua) than standard ACT.
- Effect of Artemisia annua and Artemisia afra tea infusions on schistosomiasis in a large clinical trial
PubMed ID: 30466622
Randomized trial showed Artemisia teas eliminated schistosome eggs faster than praziquantel with earlier 100% egg clearance and fewer adverse events.
Allergy relief (4)
- Artemisia annua-sublingual immunotherapy for seasonal allergic rhinitis: A randomized controlled trial
PubMed ID: 32030780
Randomized double-blind SLIT reduced nasal allergy scores and induced immunologic tolerance markers, demonstrating allergy symptom benefit.
- Clinical efficacy in one-year treatment with Artemisia annua-SLIT drops in monosensitized and polysensitized individuals
PubMed ID: 37478537
One-year SLIT produced clinically meaningful reductions in rhinoconjunctivitis symptoms and medication use with good tolerability.
- Clinical Efficacy and Safety of Artesimia annua-Sublingual Immunotherapy in Seasonal Allergic Rhinitis Patients Based on Different Intervention Time
PubMed ID: 35413714
Randomized SLIT reduced combined symptom+medication scores and was safe — clear allergy symptom benefit.
- Coseasonal initiation of Artemisia annua sublingual immunotherapy in children and adult patients with allergic rhinoconjunctivitis
PubMed ID: 39611955
One-year randomized trial in children/adults showed significant TRSS/TMS/CSMS-RC reductions vs control during pollen season.
Respiratory comfort (4)
- Coseasonal initiation of Artemisia annua sublingual immunotherapy in children and adult patients with allergic rhinoconjunctivitis
PubMed ID: 39611955
Year-long pediatric/adult SLIT trial showed significant TRSS reductions, indicating improved upper-respiratory comfort.
- Clinical efficacy in one-year treatment with Artemisia annua-SLIT drops in monosensitized and polysensitized individuals
PubMed ID: 37478537
One-year SLIT reduced seasonal rhinoconjunctivitis symptoms and medication needs — respiratory symptom benefit.
- Clinical Efficacy and Safety of Artesimia annua-Sublingual Immunotherapy in Seasonal Allergic Rhinitis Patients Based on Different Intervention Time
PubMed ID: 35413714
Pre-season SLIT reduced allergic rhinitis symptoms and medication use, implying better respiratory symptom control.
- Artemisia annua-sublingual immunotherapy for seasonal allergic rhinitis: A randomized controlled trial
PubMed ID: 32030780
Sublingual immunotherapy reduced nasal allergy symptoms (TNSS) and shifted immune profile toward tolerance, improving upper-airway comfort.
Digestive support (3)
- Effect of Artemisia annua and Artemisia afra tea infusions on schistosomiasis in a large clinical trial
PubMed ID: 30466622
Artemisia teas cleared schistosome eggs faster and caused markedly fewer GI adverse events (vomiting/abdominal pain) vs praziquantel.
- Effects of Artemisia annua and Foeniculum vulgare on chickens highly infected with Eimeria tenella (phylum Apicomplexa)
PubMed ID: 24731599
Infected chicks given A. annua leaf powder had less gut damage/lesion scores, consistent with improved digestive health (animal data).
- Artemisia annua and Artemisia afra tea infusions vs. artesunate-amodiaquine (ASAQ) in treating Plasmodium falciparum malaria in a large scale, double blind, randomized clinical trial
PubMed ID: 30668322
Large malaria RCT reported faster symptom/fever clearance and far fewer adverse events vs comparator, implying improved GI/tolerability.
Inflammation (3)
- Effect of Artemisia annua extract on treating active rheumatoid arthritis: A randomized controlled trial
PubMed ID: 28035541
Adjunct A. annua extract in RA improved clinical joint scores and lowered multiple inflammatory markers over 48 weeks.
- An open-label six-month extension study to investigate the safety and efficacy of an extract of Artemisia annua for managing pain, stiffness and functional limitation associated with osteoarthritis of the hip and knee
PubMed ID: 27806033
Open-label extension maintained symptomatic benefits and tolerability over months, supporting longer-term anti-inflammatory symptom control.
- A pilot randomized, placebo-controlled clinical trial to investigate the efficacy and safety of an extract of Artemisia annua administered over 12 weeks, for managing pain, stiffness, and functional limitation associated with osteoarthritis of the hip and knee
PubMed ID: 26631103
Small OA trial (12 weeks) found reduced pain/stiffness and improved WOMAC scores at low dose, suggesting anti-inflammatory effects.
Energy & Fatigue (2)
- Artemisia annua and Artemisia afra tea infusions vs. artesunate-amodiaquine (ASAQ) in treating Plasmodium falciparum malaria in a large scale, double blind, randomized clinical trial
PubMed ID: 30668322
Large malaria RCT produced faster fever/parasite clearance and fewer adverse events, which would be expected to restore energy more quickly.
- Effect of Artemisia annua and Artemisia afra tea infusions on schistosomiasis in a large clinical trial
PubMed ID: 30466622
Schistosomiasis trial showed faster egg clearance and hematologic recovery (Hb increase), plausibly improving patient energy/functional status.
Cold/flu relief (1)
- Artemisia annua and Artemisia afra tea infusions vs. artesunate-amodiaquine (ASAQ) in treating Plasmodium falciparum malaria in a large scale, double blind, randomized clinical trial
PubMed ID: 30668322
Large RCT showed Artemisia tea cleared fever faster (median ~24 h) than comparator (48 h) in uncomplicated falciparum malaria.
Similar by evidence
Supplements the same benefits carry qualifying findings for — a fact about the evidence graph, not a recommendation to swap.
Products with Artemisia Annua
Search all55 products whose verified label declares Artemisia Annua — not every bottle that mentions it in a title.
Being studied right now
Recruiting clinical trials registered on ClinicalTrials.gov. A trial in progress has no result yet — this is what the field is asking, not what it found.