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All study protocols

Arginine: study protocols

19 study groups say how much Arginine participants took a day. These are the doses the studies gave. They are not a recommendation.

Arginine: what the research found →

Dose per serving from products

1,044 products in our catalogue print how much Arginine a serving holds.

Most common: 500 mg to 1 g, 41% of 1,044 products.

Dose per servingProducts
50 mg or less
46
50 mg to 100 mg
47
100 mg to 250 mg
54
250 mg to 500 mg
123
500 mg to 1 g
426
1 g to 2.5 g
266
2.5 g to 5 g
68
over 5 g
14

Dose per serving from research

17 study groups in 13 studies say how much Arginine participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 2.5 g to 5 g, 53% of 17 study groups.

Daily doseStudy groups
2.5 g or less
1
2.5 g to 5 g
9
5 g to 10 g
3
10 g to 25 g
2
25 g to 50 g
2

Commonly used together

5 of 19 study groups took Arginine with something else, but nothing that 3 or more different studies gave.

19 study groups

Study
L-arginine role for stone lower ureter: A randomized controlled trial
2025 · L-Arginine group · Adults older than 18 with a single distal ureteral stone measuring 4–10 mm
1 g4 weeks51
Ultrasound evaluation of intrauterine growth restriction therapy by a nitric oxide donor (L-arginine)
2004 · L-arginine-treated group · Pregnant women with ultrasound-diagnosed intrauterine growth restriction
3 g20 days78
Decreased diabetes risk over 9 year after 18-month oral L-arginine treatment in middle-aged subjects with impaired glucose tolerance and metabolic syndrome (extension evaluation of L-arginine study)
2018 · L-arginine group · Middle-aged men and women with impaired glucose tolerance and metabolic syndrome
6.4 g540 days72
Effect of Preoperative Administration of Oral Arginine and Glutamine in Patients with Enterocutaneous Fistula Submitted to Definitive Surgery: a Prospective Randomized Trial
2020 · experimental group · Patients with enterocutaneous fistula undergoing definitive surgery
4.5 g7 days20
Randomized control trial of oral arginine therapy for children with sickle cell anemia hospitalized for pain in Nigeria
2021 · L-arginine · Children aged 5–17 years with sickle cell anemia hospitalized with vaso-occlusive pain crisis
300 mg/kg—35
L-Arginine is a feasible supplement to heal chronic anal fissure via reducing internal anal sphincter pressure: a randomized clinical trial study
2023 · L-Arginine · Adult men and women aged 18–65 with chronic anal fissure
3 g4 weeks33
Impairment of endothelial functions by acute hyperhomocysteinemia and reversal by antioxidant vitamins
1999 · Methionine-free fruit juice placebo load · Healthy adults aged 25 to 45 years; 10 men and 10 women
3 g1 day20
Long-term L-arginine supplementation improves small-vessel coronary endothelial function in humans
1998 · L-arginine · Adults with nonobstructive coronary artery disease and coronary endothelial dysfunction
9 g26 weeks—
Effects of l-Arginine Plus Vitamin C Supplementation on Physical Performance, Endothelial Function, and Persistent Fatigue in Adults with Long COVID: A Single-Blind Randomized Controlled Trial
2022 · l-arginine plus vitamin C · Men and women aged 20–60 with long COVID and persistent fatigue
3.32 g4 weeks25
Nutritional treatment for acquired immunodeficiency virus-associated wasting using beta-hydroxy beta-methylbutyrate, glutamine, and arginine: a randomized, double-blind, placebo-controlled study
2000 · HMB/Arg/Gln · HIV-infected adults with AIDS-associated wasting and at least 5% documented weight loss in the previous 3 months
14 g8 weeks22