Manuka Honey
6 benefits mapped to clinical evidence across supplements.
Dose per serving from products
22 products in our catalogue print how much Manuka Honey a serving holds.
Most common: 50 mg to 100 mg, 32% of 22 products.
| Dose per serving | Products |
|---|---|
| 5 mg or less | 1 |
| 5 mg to 10 mg | 5 |
| 10 mg to 25 mg | 0 |
| 25 mg to 50 mg | 2 |
| 50 mg to 100 mg | 7 |
| 100 mg to 250 mg | 0 |
| 250 mg to 500 mg | 6 |
| over 500 mg | 1 |
Benefit Evidence
Research sources
Antimicrobial (7)
- Randomized masked trial of the clinical efficacy of MGO Manuka Honey microemulsion eye cream for the treatment of blepharitis
PubMed ID: 31759183
Topical MGO manuka eye cream reduced lid-margin bacterial and Demodex load in blepharitis.
- Antibacterial efficacy of manuka honey, ocimum sanctum, curcuma longa and 0.2% chlorhexidine mouthwash on the level of streptococcus mutans and lactobacillus acidophilus - A randomized controlled trial
PubMed ID: 36254954
Two‑week mouthrinse RCT produced large reductions in cariogenic bacteria (S. mutans and L. acidophilus).
- Manuka honey vs. hydrogel--a prospective, open label, multicentre, randomised controlled trial to compare desloughing efficacy and healing outcomes in venous ulcers
PubMed ID: 18752540
Lower infection incidence and faster reduction of slough/wound size with manuka vs hydrogel in venous ulcers.
- Bacteriological changes in sloughy venous leg ulcers treated with manuka honey or hydrogel: an RCT
PubMed ID: 18666717
Randomized study showed 70% MRSA eradication in chronic venous ulcers with manuka vs 16% with hydrogel—strong antibacterial evidence.
- Manuka honey-impregnated dressings in the treatment of neuropathic diabetic foot ulcers
PubMed ID: 22985336
Diabetic foot-ulcer RCT documented rapid sterilization (high proportion sterile in week one) with manuka dressings.
- Randomized controlled trial of honey versus mupirocin to decolonize patients with nasal colonization of meticillin-resistant Staphylococcus aureus
PubMed ID: 29107078
Medical-grade honey cleared nasal MRSA in many adults (42.8%) though less often than mupirocin—potential alternative antimicrobial.
- Randomised controlled trial of topical antibacterial Manuka (Leptospermum species) honey for evaporative dry eye due to meibomian gland dysfunction
PubMed ID: 28585260
Adjunctive manuka eye products reduced some bacterial counts and improved signs in meibomian-gland dysfunction.
Skin repair (7)
- Novel Biomaterial Containing Gelatin, Manuka Honey, and Hydroxyapatite Enhanced Secondary Intention Healing Versus Standard Secondary Intention Healing in Mohs Surgical Defects on the Head and Distal Lower Extremities-A Randomized Controlled Trial: Pilot Study
PubMed ID: 37647156
Gelatin–manuka biomaterial reduced pain and produced thinner healed skin after Mohs surgery—favorable tissue-quality changes.
- Effect of manuka honey socket dressing on postoperative sequelae and complications following third molar extraction: A randomized controlled study
PubMed ID: 37164834
Randomized study after wisdom-tooth extraction: manuka application led to faster socket healing and fewer complications at day 7.
- Manuka honey vs. hydrogel--a prospective, open label, multicentre, randomised controlled trial to compare desloughing efficacy and healing outcomes in venous ulcers
PubMed ID: 18752540
Multicentre RCT in sloughy venous ulcers showed greater wound-area reduction and higher 12-week healing proportion with manuka vs hydrogel.
- Bacteriological changes in sloughy venous leg ulcers treated with manuka honey or hydrogel: an RCT
PubMed ID: 18666717
Randomized trial showed marked MRSA eradication in chronic venous ulcers with manuka, supporting infection-control-mediated healing.
- Manuka honey-impregnated dressings in the treatment of neuropathic diabetic foot ulcers
PubMed ID: 22985336
Randomized diabetic foot-ulcer study: manuka dressings produced faster healing and rapid sterilization vs standard care.
- Use of Honey Versus Standard Care for Hospital-Acquired Pressure Injury in Critically Ill Children: A Multicenter Randomized Controlled Trial
PubMed ID: 33181730
Multicenter RCT in critically ill children: medicated honey dressings significantly sped pressure-injury healing (median 7 vs 9 days).
- Effect of Manuka Honey on Eyelid Wound Healing: A Randomized Controlled Trial
PubMed ID: 27429228
After eyelid surgery, manuka reduced early scar pain and produced early subjective improvements though long-term objective scar appearance was similar.
Inflammation (4)
- Cost-effectiveness analysis of Manuka honey-Omega-3 combination treatments in treating oxidative stress of pediatric β-thalassemia major
PubMed ID: 38375720
Trial analysis showed reductions in oxidative-stress biomarkers when manuka (with/without omega‑3) was added—suggests anti-oxidative/anti-inflammatory effects.
- The efficacy of honey or olive oil on the severity of oral mucositis and pain compared to placebo (standard care) in children with leukemia receiving intensive chemotherapy: A randomized controlled trial (RCT)
PubMed ID: 36792398
Marked reductions in oral mucositis severity and pain in children imply decreased mucosal inflammation with topical manuka.
- Randomised assessor-masked trial evaluating topical manuka honey (Optimel) in treatment of meibomian gland dysfunction
PubMed ID: 33419788
Randomized trial of 16% manuka eye drops improved multiple objective signs of meibomian-gland dysfunction, implying anti-inflammatory/tear-film effects.
- Comparative effectiveness of adding omega-3 and Manuka honey combination to conventional therapy in preventing and treating oxidative stress in pediatric β-thalassemia major - a randomized clinical trial
PubMed ID: 37458648
Omega‑3 + manuka reduced oxidative-stress markers (8-iso-PGF2α) and LDH in children with β‑thalassemia—evidence of lowering oxidative/inflammatory stress (attributed to combination).
Oral health (4)
- Antibacterial efficacy of manuka honey, ocimum sanctum, curcuma longa and 0.2% chlorhexidine mouthwash on the level of streptococcus mutans and lactobacillus acidophilus - A randomized controlled trial
PubMed ID: 36254954
Randomized mouthrinse trial showed marked reductions in S. mutans, L. acidophilus and improved oral-hygiene index vs baseline, comparable to chlorhexidine.
- Efficacy of Manuka honey oral rinse in treatment of xerostomia among elderly patients: a randomized controlled trial
PubMed ID: 40410721
Randomized trial in elderly with dry mouth showed Manuka rinse markedly improved xerostomia symptoms, increased unstimulated salivary flow and oral health–related quality of life — direct oral-hygiene benefit.
- Effect of manuka honey socket dressing on postoperative sequelae and complications following third molar extraction: A randomized controlled study
PubMed ID: 37164834
Manuka applied in extraction sockets accelerated oral wound healing and reduced complications, supporting oral care outcomes.
- The effects of manuka honey on plaque and gingivitis: a pilot study
PubMed ID: 15125017
Chewable manuka product significantly reduced dental plaque and gum bleeding over 21 days in a pilot RCT.
Antioxidant (2)
- Cost-effectiveness analysis of Manuka honey-Omega-3 combination treatments in treating oxidative stress of pediatric β-thalassemia major
PubMed ID: 38375720
Economic/trial analysis confirmed reductions in oxidative-stress biomarkers when manuka (with/without omega‑3) was added to care.
- Comparative effectiveness of adding omega-3 and Manuka honey combination to conventional therapy in preventing and treating oxidative stress in pediatric β-thalassemia major - a randomized clinical trial
PubMed ID: 37458648
Omega‑3 + manuka group had significant reductions in oxidative-stress marker 8-iso-PGF2α and improved lipid markers in a randomized trial (combination effect).
Cough & throat (1)
- The efficacy of honey or olive oil on the severity of oral mucositis and pain compared to placebo (standard care) in children with leukemia receiving intensive chemotherapy: A randomized controlled trial (RCT)
PubMed ID: 36792398
Pediatric RCT: topical manuka mouthcare markedly reduced oral mucositis severity and pain during intensive chemotherapy—direct mucosal-soothing evidence.
Similar by evidence
Supplements the same benefits carry qualifying findings for — a fact about the evidence graph, not a recommendation to swap.
Products with Manuka Honey
Search all98 products whose verified label declares Manuka Honey — not every bottle that mentions it in a title.
Being studied right now
Recruiting clinical trials registered on ClinicalTrials.gov. A trial in progress has no result yet — this is what the field is asking, not what it found.