supp.fit

Dihydroberberine

2 benefits mapped to clinical evidence across supplements.

Dose per serving from products

66 products in our catalogue print how much Dihydroberberine a serving holds.

Most common: 100 mg to 250 mg, 50% of 66 products.

Dose per servingProducts
50 mg or less
4
50 mg to 100 mg
20
100 mg to 250 mg
33
250 mg to 500 mg
8
over 500 mg
1

Benefit Evidence

Liver markers↓, 5-HT↓

Gut serotonin↓

33 people

Cholestasis markers down

Serotonin down

33 people

Research sources

Gut health (1)
  1. Gut microbiota-mediated berberine metabolism ameliorates cholestatic liver disease by suppressing 5-hydroxytryptamine production

    PubMed ID: 41087029

    Direct mechanistic evidence: gut microbes convert berberine to dhBBR and this conversion is central to observed effects, implicating an interaction with gut microbiota.

Liver support (1)
  1. Gut microbiota-mediated berberine metabolism ameliorates cholestatic liver disease by suppressing 5-hydroxytryptamine production

    PubMed ID: 41087029

    Strongest link: mechanistic data show microbial conversion to dhBBR mediates benefit in preclinical models, and a small human trial showed better recovery of liver enzymes (GGT, ALP) with berberine+UDCA vs UDCA alone (dhBBR not directly given but implicated).

Similar by evidence

Supplements the same benefits carry qualifying findings for — a fact about the evidence graph, not a recommendation to swap.

Products with Dihydroberberine

Search all

83 products whose verified label declares Dihydroberberine — not every bottle that mentions it in a title.

Being studied right now

Recruiting clinical trials registered on ClinicalTrials.gov. A trial in progress has no result yet — this is what the field is asking, not what it found.