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Casein: study protocols

14 study groups say how much Casein participants took a day. These are the doses the studies gave. They are not a recommendation.

Casein: what the research found →

Dose per serving from research

13 study groups in 9 studies say how much Casein participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 10 g to 25 g, 54% of 13 study groups.

Daily doseStudy groups
5 g or less
1
5 g to 10 g
0
10 g to 25 g
7
25 g to 50 g
4
50 g to 100 g
1

Commonly used together

5 of 14 study groups took Casein with something else. Shown: what 3 or more different studies gave.

What was given together, not what works together.

Taken withStudy groups
Leucine
3

14 study groups

Study
Pre-sleep Protein Ingestion Increases Mitochondrial Protein Synthesis Rates During Overnight Recovery from Endurance Exercise: A Randomized Controlled Trial
2023 · CAS (micellar casein protein treatment) · Healthy men aged 18–35 years
45 g1 day12
Leucine co-ingestion improves post-prandial muscle protein accretion in elderly men
2013 · PRO · Elderly men, mean age 74.3 years
20 g1 day—
Leucine co-ingestion improves post-prandial muscle protein accretion in elderly men
2013 · PRO+LEU · Elderly men, mean age 74.3 years
20 g1 day—
ACE inhibitory casein peptide lowers blood pressure and reshapes gut microbiota in a randomized double blind placebo controlled trial
2025 · HCP group · Adults aged 30–65 with prehypertension or hypertension; men and women
300 mg8 weeks54
Whey protein lowers blood pressure and improves endothelial function and lipid biomarkers in adults with prehypertension and mild hypertension: results from the chronic Whey2Go randomized controlled trial
2016 · Calcium caseinate · Men and women aged 30–77 years with prehypertension or mild hypertension (blood pressure 120/80–159/99 mm Hg), not taking antihypertensive or cholesterol-lowering medication
56 g8 weeks38
Hemp seed protein and its hydrolysate compared with casein protein consumption in adults with hypertension: a double-blind crossover study
2024 · Casein · Adults aged 18–75 with hypertension (SBP 130–160 mmHg and DBP ≤110 mmHg), both sexes
50 g6 weeks31
A Five-Ingredient Nutritional Supplement and Home-Based Resistance Exercise Improve Lean Mass and Strength in Free-Living Elderly
2020 · Muscle5 (M5) · Sedentary or low-active, free-living men aged 65 years or older, with normal to class 1/low-risk obesity and varying degrees of age-related muscle loss
16 g12 weeks22
Muscle protein synthesis in cancer patients can be stimulated with a specially formulated medical food
2011 · experimental medical food (EXP) · Adults aged 40 years or older with radiographic evidence of advanced cancer
48.4 g1 day12
Whey protein stimulates postprandial muscle protein accretion more effectively than do casein and casein hydrolysate in older men
2011 · Casein · Healthy older men, mean age 74 ± 1 years
20 g1 day—
Whey protein stimulates postprandial muscle protein accretion more effectively than do casein and casein hydrolysate in older men
2011 · Casein hydrolysate · Healthy older men, mean age 74 ± 1 years
20 g1 day—