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Muscle cramps

Sudden involuntary muscle contractions, usually in the legs and often at night or during exercise. Trials count how often they happen, how long they last and how much they hurt.

5 supplements analyzed and ranked by clinical evidence.

Supplements5

Supplement Evidence

Electrolytes
Strong

Cramp threshold +0.86 Hz

Pain -0.7 scale

6567 studies·14 benefits
Potassium
Strong

K+ correction lowers cramps

+0.86 mmol/L

Less cramp pain

3197 studies·17 benefits
Calcium
Strong

Ca/Mg lowers cramps

Ca/Vit D prevents cramps

8772 studies·12 benefits
Magnesium
Strong

Cramp threshold +0.86 Hz

Pain -0.7 points

Fasciculation reduced

1834 studies·19 benefits
Diosmin
Moderate

Less cramps via swelling ↓

Pain relief, edema ↓

59 studies·8 benefits