Agmatine
3 benefits mapped to clinical evidence across supplements.
Dose per serving from research
5 study groups in 1 study say how much Agmatine participants took a day.
These are the doses the studies gave. They are not a recommendation.
Most common: 2.5 g to 5 g, 80% of 5 study groups.
| Daily dose | Study groups |
|---|---|
| 1 g to 2.5 g | 1 |
| 2.5 g to 5 g | 4 |
Benefit Evidence
Research sources
Metabolism (1)
- Lubiprostone in chronic kidney disease: Insights into mitochondrial function and polyamines from a randomized phase 2 clinical trial
PubMed ID: 40880481
High-quality RCT linked agmatine metabolism (aguA) and increased plasma spermidine to preserved eGFR, showing meaningful metabolic pathway effects.
Nerve health (1)
- Safety and Efficacy of Dietary Agmatine Sulfate in Lumbar Disc-associated Radiculopathy. An Open-label, Dose-escalating Study Followed by a Randomized, Double-blind, Placebo-controlled Trial
PubMed ID: 20447305
Clinical improvements in radiculopathy (pain, disability, some sensorimotor outcomes) indicate benefits to nerve-related clinical status.
Pain relief (1)
- Safety and Efficacy of Dietary Agmatine Sulfate in Lumbar Disc-associated Radiculopathy. An Open-label, Dose-escalating Study Followed by a Randomized, Double-blind, Placebo-controlled Trial
PubMed ID: 20447305
Randomized, double-blind placebo-controlled trial found clinically meaningful pain reduction with oral agmatine sulfate in lumbar radiculopathy.
Similar by evidence
Supplements the same benefits carry qualifying findings for — a fact about the evidence graph, not a recommendation to swap.
Products with Agmatine
Search all21 products whose verified label declares Agmatine — not every bottle that mentions it in a title.