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Vitamin K: study protocols

26 study groups say how much Vitamin K participants took a day. These are the doses the studies gave. They are not a recommendation.

Vitamin K: what the research found →

Dose per serving from products

4,480 products in our catalogue print how much Vitamin K a serving holds.

Most common: 50 mcg to 100 mcg, 34% of 4,480 products.

Dose per servingProducts
10 mcg or less
206
10 mcg to 25 mcg
675
25 mcg to 50 mcg
950
50 mcg to 100 mcg
1,528
100 mcg to 250 mcg
708
250 mcg to 500 mcg
122
500 mcg to 1 mg
131
over 1 mg
160

Dose per serving from research

26 study groups in 14 studies say how much Vitamin K participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 100 mcg to 250 mcg and 250 mcg to 500 mcg, 23% of 26 study groups each.

Daily doseStudy groups
50 mcg or less
2
50 mcg to 100 mcg
5
100 mcg to 250 mcg
6
250 mcg to 500 mcg
6
500 mcg to 1 mg
1
1 mg to 2.5 mg
0
2.5 mg to 5 mg
1
5 mg to 10 mg
1
10 mg to 25 mg
0
25 mg to 50 mg
4

Commonly used together

3 of 26 study groups took Vitamin K with something else, but nothing that 3 or more different studies gave.

26 study groups

Study
Vitamin K2 (menatetrenone) effectively prevents fractures and sustains lumbar bone mineral density in osteoporosis
2000 · vitamin K2-treated group · Patients with osteoporosis; age and sex not reported
45 mg2 years120
Menaquinone-7 supplementation improves arterial stiffness in healthy postmenopausal women. A double-blind randomised clinical trial
2015 · MK-7 · Healthy postmenopausal women
180 mcg3 years120
Vitamin K2 in Managing Nocturnal Leg Cramps: A Randomized Clinical Trial
2024 · vitamin K2 · Adults aged 65 years and older with at least 2 documented nocturnal leg cramp episodes during the 2-week screening period
180 mcg8 weeks103
Effects of maternal micronutrient supplementation on fetal loss and infant mortality: a cluster-randomized trial in Nepal
2003 · Multiple micronutrients · Pregnant women in rural Nepal
64 mcg——
Amelioration of osteoporosis by menatetrenone in elderly female Parkinson's disease patients with vitamin D deficiency
2002 · treated group · elderly female patients with Parkinson's disease and vitamin D and K deficiencies
45 mg1 year60
Menatetrenone ameliorates osteopenia in disuse-affected limbs of vitamin D- and K-deficient stroke patients
1998 · MK-4 group · Hemiplegic patients following stroke with vitamin D and K deficiencies
45 mg1 year54
Low-Dose Daily Intake of Vitamin K(2) (Menaquinone-7) Improves Osteocalcin γ-Carboxylation: A Double-Blind, Randomized Controlled Trials
2015 · 100 μg menaquinone-7 group (Study 1) · Postmenopausal women aged 50–69 years
100 mcg4 weeks—
Low-Dose Daily Intake of Vitamin K(2) (Menaquinone-7) Improves Osteocalcin γ-Carboxylation: A Double-Blind, Randomized Controlled Trials
2015 · MK-7 group (Study 2) · Subjects aged 20–69 years; sex and health condition not specified
100 mcg12 weeks—
Vitamin K supplementation in postmenopausal women with osteopenia (ECKO trial): a randomized controlled trial
2008 · vitamin K group · Postmenopausal women with osteopenia; mean age 59 years, range 40–82
5 mg4 years217
Menatetrenone versus alfacalcidol in the treatment of Chinese postmenopausal women with osteoporosis: a multicenter, randomized, double-blinded, double-dummy, positive drug-controlled clinical trial
2014 · Group M (menatetrenone) · Women aged 45–75 years, postmenopausal for at least 5 years, with osteoporosis
45 mg1 year118