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Magnesium and Zinc: study protocols

21 study groups took Magnesium together with Zinc. These are the doses the studies gave. They are not a recommendation.

Magnesium: what the research found →

Dose per serving from research: Magnesium

21 study groups in 16 studies say how much Magnesium participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 100 mg to 250 mg, 67% of 21 study groups.

Daily doseStudy groups
50 mg to 100 mg
4
100 mg to 250 mg
14
250 mg to 500 mg
2
over 500 mg
1

Dose per serving from research: Zinc

21 study groups in 16 studies say how much Zinc participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 25 mg to 50 mg, 33% of 21 study groups.

Daily doseStudy groups
1 mg to 2.5 mg
3
2.5 mg to 5 mg
1
5 mg to 10 mg
4
10 mg to 25 mg
4
25 mg to 50 mg
7
50 mg to 100 mg
0
100 mg to 250 mg
1
over 250 mg
1

Commonly used together

16 of 21 study groups took Magnesium and Zinc with something else. Shown: what 3 or more different studies gave.

What was given together, not what works together.

Taken withStudy groups
Vitamin D
9
Calcium
7
Vitamin C
6
Vitamin E
6
Folic Acid
3

21 study groups

Study
The effect of melatonin, magnesium, and zinc on primary insomnia in long-term care facility residents in Italy: a double-blind, placebo-controlled clinical trial
2011 · supplemented group · Long-term care facility residents with primary insomnia; mean age 78.3 ± 3.9 years; sex not reported
225 mg11.3 mg8 weeks22
The impact of vitamins and/or mineral supplementation on blood pressure in type 2 diabetes
2004 · group M · People with type 2 diabetes; age and sex not reported
200 mg30 mg90 days16
Improvement of migraine symptoms with a proprietary supplement containing riboflavin, magnesium and Q10: a randomized, placebo-controlled, double-blind, multicenter trial
2015 · Verum (investigational nutritional product) · Adults aged 18–65 of either sex with migraine with or without aura, and at least 3 migraine attacks per month before recruitment
600 mg5 mg90 days63
Improving neuropathy scores in type 2 diabetic patients using micronutrients supplementation
2011 · Group MV · Patients with type 2 diabetes
250 mg20 mg120 days—
Magnesium-Zinc-Calcium-Vitamin D Co-supplementation Improves Hormonal Profiles, Biomarkers of Inflammation and Oxidative Stress in Women with Polycystic Ovary Syndrome: a Randomized, Double-Blind, Placebo-Controlled Trial
2018 · Magnesium-zinc-calcium-vitamin D co-supplementation · Women with polycystic ovary syndrome (PCOS); age not reported
200 mg8 mg12 weeks30
Supportive treatment of vascular dysfunction in pediatric subjects with obesity: the OBELIX study
2022 · Treatment group · Children aged 6–17 years with obesity (BMI above the 95th percentile for age)
300 mg7 mg26 weeks16
Improving neuropathy scores in type 2 diabetic patients using micronutrients supplementation
2011 · Group MVB · Patients with type 2 diabetes
250 mg20 mg120 days—
The impact of vitamins and/or mineral supplementation on blood pressure in type 2 diabetes
2004 · group MV · People with type 2 diabetes; age and sex not reported
200 mg30 mg90 days17
[Vitrum osteomag in prevention of osteoporosis in postmenopausal women: results of the comparative open multicenter trial]
2004 · Group 1: Vitrum Osteomag · Postmenopausal women with osteopenia; age range not reported
80 mg15 mg1 year125
Calcium and vitamin D fortified milk reduces bone turnover and improves bone density in postmenopausal women over 1 year
2018 · intervention · Chinese postmenopausal women in Malaysia; mean age 59 years
96 mg2.4 mg1 year61
The impact of vitamin and/or mineral supplementation on lipid profiles in type 2 diabetes
2004 · group M · Adults with type 2 diabetes; age and sex not reported
200 mg30 mg90 days16
Comparison of the effects of vitamins and/or mineral supplementation on glomerular and tubular dysfunction in type 2 diabetes
2005 · group M · Patients with type 2 diabetes; age range and sex not specified
200 mg30 mg90 days16
The impact of vitamin and/or mineral supplementation on lipid profiles in type 2 diabetes
2004 · group MV · Adults with type 2 diabetes; age and sex not reported
200 mg30 mg90 days17
Randomized Study of the Effects of Zinc, Vitamin A, and Magnesium Co-supplementation on Thyroid Function, Oxidative Stress, and hs-CRP in Patients with Hypothyroidism
2021 · intervention group · Adults aged 20–65 with hypothyroidism
250 mg30 mg10 weeks43
The Effects of Magnesium and Zinc Co-Supplementation on Biomarkers of Inflammation and Oxidative Stress, and Gene Expression Related to Inflammation in Polycystic Ovary Syndrome: a Randomized Controlled Clinical Trial
2018 · Magnesium and zinc co-supplementation · Women aged 18–40 with polycystic ovary syndrome diagnosed according to the Rotterdam criteria
500 mg440 mg12 weeks30
The effects of combined magnesium and zinc supplementation on metabolic status in patients with type 2 diabetes mellitus and coronary heart disease
2020 · Magnesium plus zinc group · Women aged 40–95 with type 2 diabetes mellitus and proven two- or three-vessel coronary heart disease
250 mg150 mg12 weeks27
A Trial on The Effects of Magnesium-Zinc-Calcium-Vitamin D Co-Supplementation on Glycemic Control and Markers of Cardio-Metabolic Risk in Women with Polycystic Ovary Syndrome
2017 · Magnesium-zinc-calcium-vitamin D co-supplementation · Women with polycystic ovary syndrome (PCOS)
200 mg8 mg12 weeks30
The effects of magnesium-zinc-calcium-vitamin D co-supplementation on biomarkers of inflammation, oxidative stress and pregnancy outcomes in gestational diabetes
2019 · Magnesium-zinc-calcium-vitamin D group · Women aged 18–40 with gestational diabetes mellitus, at 24–28 weeks’ gestation at diagnosis
200 mg8 mg6 weeks30
Comparison of the effects of vitamins and/or mineral supplementation on glomerular and tubular dysfunction in type 2 diabetes
2005 · group MV · Patients with type 2 diabetes; age range and sex not specified
200 mg30 mg90 days17
Differential effects of calcium- and vitamin D-fortified milk with FOS-inulin compared to regular milk, on bone biomarkers in Chinese pre- and postmenopausal women
2016 · Intervention (Int), premenopausal women · Premenopausal women, mean age 41 years; no specific condition stated
96 mg2.4 mg12 weeks—
Differential effects of calcium- and vitamin D-fortified milk with FOS-inulin compared to regular milk, on bone biomarkers in Chinese pre- and postmenopausal women
2016 · Intervention (Int), postmenopausal women · Postmenopausal women, mean age 59 years; no specific condition stated
96 mg2.4 mg12 weeks—
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