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Leucine: study protocols

40 study groups say how much Leucine participants took a day. These are the doses the studies gave. They are not a recommendation.

Leucine: what the research found →

Dose per serving from products

3,243 products in our catalogue print how much Leucine a serving holds.

Most common: 1 g to 2.5 g, 37% of 3,243 products.

Dose per servingProducts
50 mg or less
118
50 mg to 100 mg
58
100 mg to 250 mg
111
250 mg to 500 mg
216
500 mg to 1 g
289
1 g to 2.5 g
1,193
2.5 g to 5 g
1,132
over 5 g
126

Dose per serving from research

20 study groups in 3 studies say how much Leucine participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 25 mg/kg to 50 mg/kg, 80% of 20 study groups.

Daily doseStudy groups
10 mg/kg or less
1
10 mg/kg to 25 mg/kg
1
25 mg/kg to 50 mg/kg
16
50 mg/kg to 100 mg/kg
2

Commonly used together

27 of 40 study groups took Leucine with something else. Shown: what 3 or more different studies gave.

What was given together, not what works together.

Taken withStudy groups
Whey Protein
5
Casein
3
Vitamin D
3

40 study groups

Study
Which of the branched-chain amino acids increases cerebral blood flow in hepatic encephalopathy? A double-blind randomized trial
2018 · leucine group · Adults over 18 with cirrhosis and persistent hepatic encephalopathy
30 g1 year11
Improving rehabilitation in sarcopenia: a randomized-controlled trial utilizing a muscle-targeted food for special medical purposes
2020 · Experimental formula · Adults aged 65 years or older with sarcopenia admitted for inpatient rehabilitation
5.6 g8 weeks70
Leucine co-ingestion improves post-prandial muscle protein accretion in elderly men
2013 · PRO+LEU · Elderly men, mean age 74.3 years
2.5 g1 day—
Muscle protein synthesis in cancer patients can be stimulated with a specially formulated medical food
2011 · experimental medical food (EXP) · Adults aged 40 years or older with radiographic evidence of advanced cancer
8.32 g1 day12
Enriching a protein drink with leucine augments muscle protein synthesis after resistance exercise in young and older men
2017 · SFO + LEU · Young men aged 24 ± 6 years and older men aged 70 ± 5 years
4.2 g1 day18
Protein leucine content is a determinant of shorter- and longer-term muscle protein synthetic responses at rest and following resistance exercise in healthy older women: a randomized, controlled trial
2018 · CON · Healthy women aged 65–75 years
2.6 g—11
Leucine supplementation enhances integrative myofibrillar protein synthesis in free-living older men consuming lower- and higher-protein diets: a parallel-group crossover study
2016 · Leu supplement treatment · Healthy older men aged 65–85 years, consuming lower- or higher-protein diets
15 g3 days20
Protein leucine content is a determinant of shorter- and longer-term muscle protein synthetic responses at rest and following resistance exercise in healthy older women: a randomized, controlled trial
2018 · LEU · Healthy women aged 65–75 years
8.4 g—11
Leucine, Not Total Protein, Content of a Supplement Is the Primary Determinant of Muscle Protein Anabolic Responses in Healthy Older Women
2018 · LEU · Healthy older women, mean age 69 years
6 g6 days11
Daily requirement for and splanchnic uptake of leucine in healthy adult Indians
2001 · 14 mg leucine × kg⁻¹ × d⁻¹ intake · Healthy adult Indian men
14 mg6 days10