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Leucine and Valine: study protocols

8 study groups took Leucine together with Valine. These are the doses the studies gave. They are not a recommendation.

Leucine: what the research found →

Dose per serving from research: Leucine

7 study groups in 3 studies say how much Leucine participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 25 mg to 50 mg and 50 mg to 100 mg and 10 g to 25 g, 29% of 7 study groups each.

Daily doseStudy groups
25 mg to 50 mg
2
50 mg to 100 mg
2
100 mg to 250 mg
0
250 mg to 500 mg
0
500 mg to 1 g
0
1 g to 2.5 g
0
2.5 g to 5 g
1
5 g to 10 g
0
10 g to 25 g
2

Dose per serving from research: Valine

7 study groups in 3 studies say how much Valine participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 5 mg to 10 mg and 10 mg to 25 mg and 10 g to 25 g, 29% of 7 study groups each.

Daily doseStudy groups
5 mg to 10 mg
2
10 mg to 25 mg
2
25 mg to 50 mg
0
50 mg to 100 mg
0
100 mg to 250 mg
0
250 mg to 500 mg
0
500 mg to 1 g
0
1 g to 2.5 g
1
2.5 g to 5 g
0
5 g to 10 g
0
10 g to 25 g
2

Commonly used together

4 of 8 study groups took Leucine and Valine with something else. Shown: what 3 or more different studies gave.

What was given together, not what works together.

Taken withStudy groups
Isoleucine
4

8 study groups

Study
Anti-sarcopenic effect of leucine-enriched branched-chain amino acid supplementation among elderly chronic kidney disease patients: a double-blinded randomized controlled trial
2025 · oral mixed BCAA supplementation · Patients with chronic kidney disease aged over 65 years
4.5 g1.5 g12 weeks29
Acute oral administration of a tyrosine and phenylalanine-free amino acid mixture reduces exercise capacity in the heat
2013 · TYR-free · Healthy, moderately trained men unacclimated to exercise in the heat
22.5 g17.5 g1 day8
Acute oral administration of a tyrosine and phenylalanine-free amino acid mixture reduces exercise capacity in the heat
2013 · BAL · Healthy, moderately trained men unacclimated to exercise in the heat
22.5 g17.5 g1 day8
Attenuation of the protein wasting associated with bed rest by branched-chain amino acids
1999 · BCAA group · Healthy subjects undergoing bed rest
30 mmol30 mmol6 days8
Branched-chain amino acid interactions with reference to amino acid requirements in adult men: valine metabolism at different leucine intakes
1991 · 20 mg valine/kg body weight/day with 80 mg leucine/kg/day · Six young adult men
80 mg20 mg5 days6
Branched-chain amino acid interactions with reference to amino acid requirements in adult men: valine metabolism at different leucine intakes
1991 · 20 mg valine/kg body weight/day with 40 mg leucine/kg/day · Six young adult men
40 mg20 mg5 days6
Branched-chain amino acid interactions with reference to amino acid requirements in adult men: valine metabolism at different leucine intakes
1991 · 10 mg valine/kg body weight/day with 80 mg leucine/kg/day · Six young adult men
80 mg10 mg5 days6
Branched-chain amino acid interactions with reference to amino acid requirements in adult men: valine metabolism at different leucine intakes
1991 · 10 mg valine/kg body weight/day with 40 mg leucine/kg/day · Six young adult men
40 mg10 mg5 days6
Leucine and Valine: study protocols | supp.fit