supp.fit

Leucine and Branched-Chain Amino Acids: study protocols

17 study groups took Leucine together with Branched-Chain Amino Acids. These are the doses the studies gave. They are not a recommendation.

Leucine: what the research found →

Dose per serving from research: Leucine

10 study groups in 4 studies say how much Leucine participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 10 mg to 25 mg, 40% of 10 study groups.

Daily doseStudy groups
10 mg to 25 mg
4
25 mg to 50 mg
2
50 mg to 100 mg
0
100 mg to 250 mg
0
250 mg to 500 mg
0
500 mg to 1 g
0
1 g to 2.5 g
2
2.5 g to 5 g
2

Dose per serving from research: Branched-Chain Amino Acids

13 study groups in 2 studies say how much Branched-Chain Amino Acids participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 10 mg/kg to 25 mg/kg, 54% of 13 study groups.

Daily doseStudy groups
5 mg/kg or less
1
5 mg/kg to 10 mg/kg
1
10 mg/kg to 25 mg/kg
7
25 mg/kg to 50 mg/kg
2
50 mg/kg to 100 mg/kg
2

Commonly used together

10 of 17 study groups took Leucine and Branched-Chain Amino Acids with something else. Shown: what 3 or more different studies gave.

What was given together, not what works together.

Taken withStudy groups
Isoleucine
8

17 study groups

Study
The Effects of Timing of a Leucine-Enriched Amino Acid Supplement on Body Composition and Physical Function in Stroke Patients: A Randomized Controlled Trial
2020 · breakfast group · Adults aged 40 years and older admitted for rehabilitation after cerebral infarction, cerebral hemorrhage, or subarachnoid hemorrhage
1.6 g125 mL60 days23
The Effects of Timing of a Leucine-Enriched Amino Acid Supplement on Body Composition and Physical Function in Stroke Patients: A Randomized Controlled Trial
2020 · post-exercise group · Adults aged 40 years and older admitted for rehabilitation after cerebral infarction, cerebral hemorrhage, or subarachnoid hemorrhage
1.6 g125 mL60 days23
Post-exercise branched chain amino acid supplementation does not affect recovery markers following three consecutive high intensity resistance training bouts compared to carbohydrate supplementation
2016 · BCAA-CHO · Resistance-trained, apparently healthy males; mean age 21.8 years
3 g—4 days15
The daily valine requirement of healthy adult Indians determined by the 24-h indicator amino acid balance approach
2005 · valine intake 5 mg x kg(-1) x d(-1) · healthy, well-nourished Indian men
40 mg/kg5 mg/kg7 days—
The daily valine requirement of healthy adult Indians determined by the 24-h indicator amino acid balance approach
2005 · valine intake 10 mg x kg(-1) x d(-1) · healthy, well-nourished Indian men
40 mg/kg10 mg/kg7 days—
The daily valine requirement of healthy adult Indians determined by the 24-h indicator amino acid balance approach
2005 · valine intake 15 mg x kg(-1) x d(-1) · healthy, well-nourished Indian men
40 mg/kg15 mg/kg7 days—
The daily valine requirement of healthy adult Indians determined by the 24-h indicator amino acid balance approach
2005 · valine intake 20 mg x kg(-1) x d(-1) · healthy, well-nourished Indian men
40 mg/kg20 mg/kg7 days—
The daily valine requirement of healthy adult Indians determined by the 24-h indicator amino acid balance approach
2005 · valine intake 25 mg x kg(-1) x d(-1) · healthy, well-nourished Indian men
40 mg/kg25 mg/kg7 days—
The daily valine requirement of healthy adult Indians determined by the 24-h indicator amino acid balance approach
2005 · valine intake 30 mg x kg(-1) x d(-1) · healthy, well-nourished Indian men
40 mg/kg30 mg/kg7 days—
The daily valine requirement of healthy adult Indians determined by the 24-h indicator amino acid balance approach
2005 · valine intake 35 mg x kg(-1) x d(-1) · healthy, well-nourished Indian men
40 mg/kg35 mg/kg7 days—
Branched-chain amino acid interactions with reference to amino acid requirements in adult men: leucine metabolism at different valine and isoleucine intakes
1991 · Phase 1: leucine 40 mg/kg/day, valine 80 mg/kg/day, isoleucine 62 mg/kg/day · Healthy young adult men; six subjects were in phase 1
40 mg80 mg/kg5 days—
Branched-chain amino acid interactions with reference to amino acid requirements in adult men: leucine metabolism at different valine and isoleucine intakes
1991 · Phase 1: leucine 15 mg/kg/day, valine 80 mg/kg/day, isoleucine 62 mg/kg/day · Healthy young adult men; six subjects were in phase 1
15 mg80 mg/kg5 days—
Branched-chain amino acid interactions with reference to amino acid requirements in adult men: leucine metabolism at different valine and isoleucine intakes
1991 · Phase 1: leucine 15 mg/kg/day, valine 20 mg/kg/day, isoleucine 62 mg/kg/day · Healthy young adult men; six subjects were in phase 1
15 mg20 mg/kg5 days—
Branched-chain amino acid interactions with reference to amino acid requirements in adult men: leucine metabolism at different valine and isoleucine intakes
1991 · Phase 2: leucine 15 mg/kg/day, valine 20 mg/kg/day, isoleucine 62 mg/kg/day · Healthy young adult men; five subjects were in phase 2
15 mg20 mg/kg5 days—
Branched-chain amino acid interactions with reference to amino acid requirements in adult men: leucine metabolism at different valine and isoleucine intakes
1991 · Phase 2: leucine 40 mg/kg/day, valine 20 mg/kg/day, isoleucine 20 mg/kg/day · Healthy young adult men; five subjects were in phase 2
40 mg20 mg/kg5 days—
Branched-chain amino acid interactions with reference to amino acid requirements in adult men: leucine metabolism at different valine and isoleucine intakes
1991 · Phase 2: leucine 15 mg/kg/day, valine 20 mg/kg/day, isoleucine 20 mg/kg/day · Healthy young adult men; five subjects were in phase 2
15 mg20 mg/kg5 days—
Dileucine-supplemented essential amino acids support whole-body anabolism after resistance exercise and serum-stimulated cell-based anabolism
2025 · Branched-chain amino acid (BCAA) supplement · Healthy recreationally active adults, 27.0 ± 4.7 years old; 8 men and 4 women
3.1 g1.5 g1 day12
Leucine and Branched-Chain Amino Acids: study protocols | supp.fit