Leucine and Whey Protein: study protocols

5 study groups took Leucine together with Whey Protein. These are the doses the studies gave. They are not a recommendation.

Dose per serving from research: Leucine

5 study groups in 5 studies say how much Leucine participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 5 g to 10 g, 80% of 5 study groups.

Daily dose	Study groups
2.5 g to 5 g	1
5 g to 10 g	4

5 study groups in 5 studies say how much Whey Protein participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 25 g to 50 g, 60% of 5 study groups.

Daily dose	Study groups
10 g to 25 g	2
25 g to 50 g	3

4 of 5 study groups took Leucine and Whey Protein with something else. Shown: what 3 or more different studies gave.

What was given together, not what works together.

Taken with	Study groups
Vitamin D	3

5 study groups

Study
Improving rehabilitation in sarcopenia: a randomized-controlled trial utilizing a muscle-targeted food for special medical purposes 2020 · Experimental formula · Adults aged 65 years or older with sarcopenia admitted for inpatient rehabilitation	5.6 g	40 g	8 weeks	70
Muscle protein synthesis in cancer patients can be stimulated with a specially formulated medical food 2011 · experimental medical food (EXP) · Adults aged 40 years or older with radiographic evidence of advanced cancer	8.32 g	23.8 g	1 day	12
Thirteen weeks of supplementation of vitamin D and leucine-enriched whey protein nutritional supplement attenuates chronic low-grade inflammation in sarcopenic older adults: the PROVIDE study 2019 · active group · Adults aged 65 years or older with mild to moderate physical-function limitations and class I or II sarcopenia	6 g	40 g	13 weeks	184
Leucine, Not Total Protein, Content of a Supplement Is the Primary Determinant of Muscle Protein Anabolic Responses in Healthy Older Women 2018 · WPI · Healthy older women, mean age 69 years	6 g	50 g	6 days	11
Safety and tolerability of 6-month supplementation with a vitamin D, calcium and leucine-enriched whey protein medical nutrition drink in sarcopenic older adults 2020 · One-serving WP-MND group during the open-label extension · Adults aged 65 years or older with sarcopenia who continued from the RCT	3 g	20 g	13 weeks	133