Caffeine: study protocols
29 study groups say how much Caffeine participants took a day. These are the doses the studies gave. They are not a recommendation.
Dose per serving from products
1,641 products in our catalogue print how much Caffeine a serving holds.
Most common: 100 mg to 250 mg, 41% of 1,641 products.
| Dose per serving | Products |
|---|---|
| 10 mg or less | 54 |
| 10 mg to 25 mg | 85 |
| 25 mg to 50 mg | 236 |
| 50 mg to 100 mg | 394 |
| 100 mg to 250 mg | 679 |
| 250 mg to 500 mg | 179 |
| over 500 mg | 14 |
Dose per serving from research
18 study groups in 7 studies say how much Caffeine participants took a day.
These are the doses the studies gave. They are not a recommendation.
Most common: 50 mg to 100 mg, 44% of 18 study groups.
| Daily dose | Study groups |
|---|---|
| 25 mg to 50 mg | 2 |
| 50 mg to 100 mg | 8 |
| 100 mg to 250 mg | 3 |
| 250 mg to 500 mg | 4 |
| over 500 mg | 1 |
Commonly used together
1 of 29 study groups took Caffeine with something else, but nothing that 3 or more different studies gave.
29 study groups
| Study | |||
|---|---|---|---|
| Efficacy and safety of a fixed-dose combination of ibuprofen and caffeine in the management of moderate to severe dental pain after third molar extraction 2018 · Caffeine · Men and women aged 18–55 with moderate or severe postoperative dental pain after extraction of 3–4 impacted third molars | 100 mg | 1 day | 70 |
| Dose and timing effects of caffeine on subsequent sleep: a randomized clinical crossover trial 2025 · 100 mg caffeine, 12 hours before bedtime · Healthy males aged 18–40 years with moderate habitual caffeine intake (<300 mg/day) | 100 mg | 3 weeks | 23 |
| Dose and timing effects of caffeine on subsequent sleep: a randomized clinical crossover trial 2025 · 100 mg caffeine, 8 hours before bedtime · Healthy males aged 18–40 years with moderate habitual caffeine intake (<300 mg/day) | 100 mg | 3 weeks | 23 |
| Dose and timing effects of caffeine on subsequent sleep: a randomized clinical crossover trial 2025 · 100 mg caffeine, 4 hours before bedtime · Healthy males aged 18–40 years with moderate habitual caffeine intake (<300 mg/day) | 100 mg | 3 weeks | 23 |
| Multiple caffeine doses maintain vigilance during early morning operations 2005 · 50 mg caffeine group · Adults (28 men and 20 women), sleep-deprived during an overnight operation; age and health status not reported | 150 mg | 1 day | — |
| Early effects of caffeinated and decaffeinated coffee on subjective state and gender differences 2008 · Caffeine · Healthy undergraduate volunteers, mean age 22.03 years; men and women; no stated condition | 100 mg | 1 day | — |
| Effect of caffeine on ibuprofen analgesia in postoperative oral surgery pain 1991 · ibuprofen 100 mg with caffeine 100 mg · Outpatients with postoperative pain after surgical removal of impacted third molars; age and sex not specified | 100 mg | 1 day | — |
| Effect of caffeine on ibuprofen analgesia in postoperative oral surgery pain 1991 · ibuprofen 200 mg with caffeine 100 mg · Outpatients with postoperative pain after surgical removal of impacted third molars; age and sex not specified | 100 mg | 1 day | — |
| High dose caffeine citrate for extubation of preterm infants: a randomised controlled trial 2004 · 20 mg/kg/day caffeine citrate group · Neonates born at less than 30 weeks gestation who were ventilated for more than 48 hours | 20 mg/kg | — | — |
| High dose caffeine citrate for extubation of preterm infants: a randomised controlled trial 2004 · 5 mg/kg/day caffeine citrate group · Neonates born at less than 30 weeks gestation who were ventilated for more than 48 hours | 5 mg/kg | — | — |