Zinc, Vitamin B12 and Vitamin B6: study protocols
7 study groups took Zinc together with Vitamin B12 and Vitamin B6. These are the doses the studies gave. They are not a recommendation.
Dose per serving from research: Zinc
7 study groups in 7 studies say how much Zinc participants took a day.
These are the doses the studies gave. They are not a recommendation.
Most common: 5 mg to 10 mg, 71% of 7 study groups.
| Daily dose | Study groups |
|---|---|
| 5 mg to 10 mg | 5 |
| 10 mg to 25 mg | 1 |
| over 25 mg | 1 |
Dose per serving from research: Vitamin B12
6 study groups in 6 studies say how much Vitamin B12 participants took a day.
These are the doses the studies gave. They are not a recommendation.
Most common: 0.5 mcg to 1 mcg, 50% of 6 study groups.
| Daily dose | Study groups |
|---|---|
| 0.5 mcg to 1 mcg | 3 |
| 1 mcg to 2.5 mcg | 0 |
| 2.5 mcg to 5 mcg | 2 |
| 5 mcg to 10 mcg | 1 |
Dose per serving from research: Vitamin B6
6 study groups in 6 studies say how much Vitamin B6 participants took a day.
These are the doses the studies gave. They are not a recommendation.
Most common: 250 mcg to 500 mcg, 50% of 6 study groups.
| Daily dose | Study groups |
|---|---|
| 250 mcg to 500 mcg | 3 |
| 500 mcg to 1 mg | 0 |
| 1 mg to 2.5 mg | 1 |
| 2.5 mg to 5 mg | 2 |
Commonly used together
7 of 7 study groups took Zinc, Vitamin B12 and Vitamin B6 with something else. Shown: what 3 or more different studies gave. The 10 most common of 14.
What was given together, not what works together.
| Taken with | Study groups |
|---|---|
| Iron | 6 |
| Copper | 5 |
| Iodine | 5 |
| Vitamin A | 5 |
| Vitamin C | 5 |
| Vitamin D | 5 |
| Vitamin E | 5 |
| Folic Acid | 4 |
| Niacin | 4 |
| Vitamin K | 4 |
7 study groups
| Study | |||||
|---|---|---|---|---|---|
| Effects of maternal micronutrient supplementation on fetal loss and infant mortality: a cluster-randomized trial in Nepal 2003 · Multiple micronutrients · Pregnant women in rural Nepal | 30 mg | 2.6 mcg | 2.2 mg | — | — |
| Effect of micronutrient supplementation on diarrhoeal disease among stunted children in rural South Africa 2009 · multiple micronutrients · children aged 6–24 months; three cohorts: HIV-infected children, HIV-uninfected children born to HIV-infected mothers, and HIV-uninfected children born to HIV-uninfected mothers | 10 mg | 0.9 mcg | 500 mcg | 548 days | — |
| Effect of preventive supplementation with zinc and other micronutrients on non-malarial morbidity in Tanzanian pre-school children: a randomized trial 2012 · Multi-nutrients with zinc · Children aged 6–60 months with height-for-age z-score ≤−1.5 SD, in rural Tanzania | 10 mg | — | — | — | 151 |
| Effect on longitudinal growth and anemia of zinc or multiple micronutrients added to vitamin A: a randomized controlled trial in children aged 6-24 months 2010 · Multiple micronutrients · Children enrolled at 6 months and followed to 24 months in rural South Africa; HIV-infected and HIV-uninfected children, both sexes | 10 mg | 0.9 mcg | 500 mcg | 548 days | 126 |
| Maternal B-vitamin and vitamin D status before, during, and after pregnancy and the influence of supplementation preconception and during pregnancy: Prespecified secondary analysis of the NiPPeR double-blind randomized controlled trial 2023 · intervention · Women planning pregnancy; generally healthy, recruited before conception | 10 mg | 5.2 mcg | 2.6 mg | — | 870 |
| Multiple micronutrient supplementation improves micronutrient status in primary school children in Hai Phong City, Vietnam: a randomised controlled trial 2021 · intervention · Children aged 6–9 years, apparently healthy, in rural Hai Phong City, Vietnam; included undernourished, normal-weight, and overweight/obese children | 10 mg | 0.9 mcg | 500 mcg | 22 weeks | 175 |
| Nutraceutical approaches to homocysteine lowering in hypertensive subjects at low cardiovascular risk: a multicenter, randomized clinical trial 2016 · Normocis 400® group · Adults with stage 1 essential hypertension and hyper-homocysteinemia (HCys ≥15 μmol/L), without a history of cardiovascular or cerebrovascular disease; mean age 62.8 years, 63.5% male | 12.5 mg | 5 mcg | 3 mg | 60 days | 52 |